ライフサイエンスコーパス: alphavbeta5 integrin

1 uitment via Rac1 both require MFG-E8-ligated alphavbeta5 integrin.

2 sis independently of the OS binding receptor alphavbeta5 integrin.

3 irectly associates with the beta5 subunit of alphaVbeta5 integrin.

4 tors that mediate this uptake, they lack the alphavbeta5 integrin.

5 hich tetraspanins CD9 and CD81 link JAM-A to alphavbeta5 integrin.

6 a by interacting with glomerular endothelial alphavbeta5 integrin.

7 sue and cell lines expressed alphavbeta3 and alphavbeta5 integrins.

8 rved with antibodies against alphaVbeta3 and alphaVbeta5 integrins.

9 ization studies suggest that alphaVbeta3 and alphaVbeta5 integrins also play roles in KSHV entry.

10 an sulfate proteoglycan-bound AAV-2 requires alphaVbeta5 integrin and activation of the small GTP-bin

11 etinal pigment epithelial (RPE) cells employ alphavbeta5 integrin and CD36 receptors to phagocytose p

12 ique profile of receptors, in particular the alphavbeta5 integrin and CD36.

13 Rac1 activation during phagocytosis requires alphavbeta5 integrin and its ligand milk fat globule EGF

14 a3, alpha5, beta1, alpha5beta1, alphavbeta3, alphavbeta5 integrins and CD36) and inhibitors of specif

15 Expression of alphavbeta3- or alphavbeta5-integrins and selectins is widespread on blo

16 s with soluble alpha3beta1, alphaVbeta3, and alphaVbeta5 integrins, and cumulative inhibition was obs

17 cRGD) with nanomolar activity as alphavbeta3/alphavbeta5 integrin antagonists.

18 These data indicate that alphavbeta3 or alphavbeta5 integrins are not essential for tumor growth

19 These data indicate that alphavbeta3 and alphavbeta5 integrins are not essential for vascular dev

20 alphavbeta3 or alphavbeta5 integrins are widely expressed on blood and

21 unction-blocking monoclonal antibody against alphavbeta5 integrin, as could differentiation in the wi

22 JAM-A binds Csk and inhibits the activity of alphavbeta5 integrin-associated Src.

23 rotein stonin1 as a marker for non-canonical alphaVbeta5 integrin-based adhesions and demonstrate by

24 Stratified squamous epithelia express the alphavbeta5 integrin, but in squamous cell carcinomas (S

25 bona fide engulfment pathway in concert with alphavbeta5 integrin by regulating cytoskeletal assembla

26 ng endothelial cell monolayers via RhoA- and alphavbeta5 integrin-dependent mechanisms.

27 Daily alphavbeta5 integrin-dependent phagocytosis of spent pho

28 cid uptake through alphavbeta3 integrin- and alphavbeta5 integrin-dependent phosphorylation of Akt by

29 ntially express alphavbeta1, alphavbeta3 and alphavbeta5 integrins during differentiation in vitro.

30 e alpha1beta1, alpha2beta1, alphavbeta3, and alphavbeta5 integrins each support dermal microvascular

31 ind that proper regulation of CIL depends on alphavbeta5 integrin engagement.

32 to loss of either the phagocytosis receptor alphavbeta5 integrin, expressed by the RPE but not by ph

33 phagocytosis was evaluated by knocking down alphavbeta5 integrin expression with siRNA against the h

34 asts as well as motility, matrix deposition, alphavbeta5 integrin expression, and radical oxygen spec

35 The alphavbeta5 integrin-FAK-mediated pathway regulates phag

36 Inhibition of alphavbeta3 or alphavbeta5 integrin function has been reported to suppr

37 Using its alphaVbeta5 integrin, HSG cells attached to BSP but not

38 The role of alphavbeta5 integrin in phagocytosis was evaluated by kn

39 used to determine levels of alphavbeta3 and alphavbeta5 integrins in TM tissue and cultures of norma

40 nt phosphatidylserine with the RPE receptors alphavbeta5 integrin, inducing cytosolic signaling towar

41 Cilengitide is a selective alphavbeta3 and alphavbeta5 integrin inhibitor.

42 The alphavbeta5 integrin is known to promote Ad cell entry.

43 ng and internalization studies indicate that alphaVbeta5 integrin is not a primary attachment recepto

44 3 integrin expression and signalling through alphavbeta5 integrin may be critical to continued differ

45 The alphavbeta5 integrin may have an important role in acute

46 In summary, our results indicate that alphaVbeta5 integrin-mediated endocytosis of AAV-2 occur

47 expression of mutant beta5 integrin, nor was alphavbeta5 integrin-mediated engulfment modulated by cl

48 h cell surface alpha3beta1, alphaVbeta3, and alphaVbeta5 integrin molecules and tyrosine kinase ephri

49 nd OPN knockdown inactivated alphavbeta3 and alphavbeta5 integrins, negligibly affecting their expres

50 We suggest that the alphavbeta5 integrin plays a critical role in the traffi

51 Here we determined that alphaVbeta5 integrin plays a part in efficient AAV infec

52 pidermal growth factor like 8 (MFGE8) to the alphavbeta5 integrin promotes termination of insulin rec

53 activated promptly after light onset via the alphavbeta5 integrin receptor and its ligand MFG-E8, thu

54 se results demonstrate an essential role for alphavbeta5 integrin receptors and their downstream sign

55 Cilengitide, an inhibitor of alphavbeta3 and alphavbeta5 integrin receptors, demonstrated minimal tox

56 ro through interactions with alphavbeta3 and alphavbeta5 integrin receptors.

57 broblast-to-CAF activation, which depends on alphavbeta5-integrin redistribution of pFAK-independent

58 Knockdown of alphavbeta5 integrin reduced phagocytosis by approximate

59 selective exchange of components on a stable alphaVbeta5 integrin scaffold.

60 This study supports the idea that alphaVbeta5 integrin serves as a co-receptor for AAV-2 v

61 Genetically defined cells expressing alphaVbeta5 integrin showed increased susceptibility to

62 the retinal pigment epithelium (RPE) employs alphavbeta5 integrin to recognize spent photoreceptor ou

63 that bound to VN, competing with alphavbeta3/alphavbeta5 integrin/VN binding, thus promoting cell det

64 ics that selectively bind to alphavbeta3 and alphavbeta5 integrins were synthesized and covalently do

65 e two vitronectin receptors, alphavbeta3 and alphavbeta5 integrin, which have been shown to cooperate