ライフサイエンスコーパス: alternative

1 but carbonate rocks may serve as a potential alternative.

2 pneumonia can be a reasonable and inclusive alternative.

3 emerging as a more versatile and economical alternative.

4 echanical relays have emerged as a promising alternative.

5 ar chiral aldehyde over the achiral branched alternative.

6 vatives are being investigated as preferable alternatives.

7 d urbanization and absence of viable cleaner alternatives.

8 l to fully understand the trade-offs between alternatives.

9 's superior performance relative to existing alternatives.

10 s, static metasurfaces are used as competent alternatives.

11 mitigation benefits compared to fossil fuel alternatives.

12 Cassette exons and alternative 3' splice sites were the most frequently fou

13 dynamic interplay between distinct RBPs and alternative 5' UTRs in neuronal development and undersco

14 However, recent work proposes an alternative account of efficiency: In certain contexts,

15 luding dampening of the T helper 1 response, alternative activation of macrophages, efferocytosis, an

16 eased mortality for polymyxins compared with alternative agents.

17 ates that are orders of magnitude lower than alternative algorithms while substantially increasing th

18 on using 2-bromoethylamine was applied as an alternative alkylation strategy to introduce artificial

19 iption factor)-binding motifs, inferred from alternative alleles at the haQTLs, implied a surprising

20 ss preanalytic challenges, we first consider alternative anatomic sites for specimen collection, then

21 ZIKV NS1 protein may be an alternative antigen for vaccine development, since antib

22 nesses of HRP2-based diagnosis compared with alternative antigens.

23 rs (nAChRs) as a lead for the development of alternative antivenoms.

24 is activated through the classical (CP), the alternative (AP), and the lectin pathway (LP) based on t

25 An alternative approach is to change the magnetic state dir

26 o not align with underlying neurobiology, an alternative approach is to identify neurobiologically in

27 Here, we used an alternative approach to interpret the functional signifi

28 Here an alternative approach to the existing selective reverse I

29 s to be unfeasible, and the "treatment stage alternative" approach, which proposes further therapeuti

30 Alternative approaches aim to infuse allogeneic mesenchy

31 While alternative approaches exist, most analysts are not fami

32 Thus, the field has sought alternative approaches that harness the dimensions of em

33 Alternative approaches that use relaxed bwa parameter se

34 Here we use an alternative architecture that realizes a giant atom by c

35 increasing drive to minimize usage, and what alternatives are currently available.

36 , structured RNA elements represent a potent alternative as drug targets.

37 to be an important consideration in chemical alternatives assessment.

38 ses were undertaken to examine the effect of alternative assumptions and uncertainty in model paramet

39 metal batteries are considered as attractive alternatives beyond lithium-ion batteries.

40 g., donepezil, epoetin alfa); (3) drugs with alternative biologic explanations for the association (e

41 ally constrained HDAC8 inhibitors present an alternative biological probe for further determining the

42 BRS Xingu is presented as an alternative blackberry with potential for industrializat

43 Rapid-set liquid bandages are efficient alternatives but lack durability or inherent infection c

44 e strips are an emerging, minimally invasive alternative, but global transcriptomic profiling in earl

45 he enzymatic synthesis of DNA is a promising alternative, but thus far has not been well demonstrated

46 roducts covering the classical/lectin (C4d), alternative (C3bBbP) and common pathway (C3bc, C5a, and

47 g a multipronged approach: We have chosen an alternative Cas protein (CasRx), inserted the deaminase

48 These include convection-enhanced delivery, alternative catheter delivery, and neuro-surgically appl

49 sistant to single-agent chemotherapy receive alternative chemotherapy regimens, which, although effec

50 Mice were trained in a two-alternative choice task, in which they had to associate

51 heparan sulfate proteoglycans (HSPGs) act as alternative co-receptors for RSPO3 using a combination o

52 ed, thus supporting the use and transport of alternative collection media and specimen types under a

53 models to quantify potential net impacts of alternative compensation policies on biodiversity (indic

54 ts within complement factor H (CFH), a major alternative complement pathway regulator, are associated

55 an ApoE activated both the classical and the alternative complement pathways.

56 We used stability selection as an alternative computational approach to identify an optima

57 gate, which distinguishes between closed and alternative conformations.

58 How neural activity and attention to choice alternatives contribute to reward decisions during tempo

59 which arise during choices between economic alternatives defined by two attributes.

60 9.1%; 95% CI, 4.0-14.2; P = .04) and with an alternative definition of clinically relevant serrated p

61 space, between the sclera and choroid, is an alternative delivery technique developed with the ration

62 2% of presumed germinomas on imaging yielded alternative diagnoses on biopsy, adding support for path

63 esentation, histopathology, and exclusion of alternative diagnoses were summarized.

64 higher sensitivity than previously described alternative diagnostic methods and showed a broad linear

65 of planar chirality by lithiation, with the alternative diastereoisomer formed by use of a deuterium

66 The alternative diastereoisomers were formed selectively by

67 The HIV Prevention Trials Network (HPTN) 067/Alternative Dosing to Augment PrEP Pill Taking (ADAPT) S

68 rms, but the macroevolutionary processes and alternative drivers explaining this pattern remain elusi

69 roval of tolvaptan, safer and more effective alternative drugs are clearly needed to slow disease pro

70 itu methane conditions were observed, making alternative electron acceptors important to support AOM

71 omotes redox reactions through generation of alternative electron transfer pathways, while it reduces

72 iderable efforts have ensued to characterize alternative electrophiles that exhibit irreversible or r

73 Their utility as alternative electrophilic warheads for chemical biologic

74 The alternative endogenous ligand macrophage migration inhib

75 An alternative explanation is that multimers could become e

76 hers have challenged such findings, offering alternative explanations.

77 We propose an alternative falsification test that compares IV balance

78 mples), it is optimal to draw one sample per alternative, favoring breadth.

79 of App1 as an in vitro synthesis tool and an alternative for capsule polymer provision.

80 Biological control is a potential alternative for management of this severe plant pathogen

81 balanced data, which is simple and can be an alternative for performing feature selection in class-im

82 this scalable method provides a sustainable alternative for preparing N,O-biaryl compounds that are

83 dization LC-MS/MS was considered an improved alternative for quantitation of ASOs and metabolites in

84 es integrating nanomaterials offers a viable alternative for rapid and sensitive determination of the

85 of N(2) to NH(3) is emerging as a promising alternative for sustainable and distributed production o

86 us redox flow batteries (RFBs) are promising alternatives for large-scale energy storage.

87 the limitations of HbA(1c), and we consider alternatives for monitoring glycaemic control.

88 We discuss alternatives for risk prediction, including a secondary

89 Nanoencapsulation provides new alternatives for the food industry, enabling a controlle

90 at FCEVs could compete with conventional and alternative fuel vehicles by 2035.

91 w accumulating evidence of antibiosis and of alternative functions of antibiotics exhibited at subinh

92 for repression of specific retinal fates and alternative gene regulatory networks.

93 specificity transitions would be limited in alternative geometries.

94 As a potential bentonite alternative, grape seeds powder (GSP) was added to four

95 New key questions focused on the yield of alternative HBV screening strategies and the accuracy of

96 dex, physical activity, alcohol consumption, Alternative Healthy Eating Index, and diabetes.

97 1-heterodifunctionalized product in favor of alternative homodifunctionalized, 1,2-heterodifunctional

98 Careful monitoring may be an alternative if patients and providers can adhere to freq

99 h for healthier and environmentally friendly alternatives in agriculture.

100 Latent block models can be alternatives in this case but they also often show subop

101 nase inhibitors could lay the foundation for alternative infectious disease therapy using available t

102 ted in the years that followed, with several alternative interpretations put forth to explain the eff

103 This alternative is supported by new evidence from real-time

104 An alternative is to introduce genome editing reagents and

105 Based on six alternative land-use plans, we identified the synergies

106 integrated the C-circle assay [a marker for alternative lengthening of telomeres (ALT)], TERT mRNA e

107 First, we show that the selection of alternative life histories depends on both the mean and

108 lls engaged PD-1(+) macrophages, inducing an alternative M2-like program, which had crippling effects

109 In Malawi, the limited availability of alternatives means that strategies to prevent the spread

110 Despite the rising popularity of plant-based alternative meats, there is limited evidence of the heal

111 This basic tenet was challenged by an alternative mechanism, in which the major reaction of HO

112 This alternative mechanistic paradigm decouples the bond-brea

113 fy and pattern the endoderm while repressing alternative mesectoderm fates.

114 The derived equations create an alternative method for estimating label incorporation.

115 is of volatile oxidation compounds can be an alternative method for p-anisidine value.

116 In addition to our findings, an alternative method of modeling time-dependent inhibition

117 ITC-SIS serves as a good alternative method to detect disease susceptibility loci

118 Thus, DoMY-Seq provides an unbiased alternative method to rapidly identify the domains invol

119 p utilizing vacuum infiltration, which is an alternative method to stable transformation.

120 oteomics analysis has emerged as a promising alternative method when seeking to assess panels of prot

121 T expression and telomere length suggests an alternative method whereby tumor cells escape the critic

122 wcasing the advantages of this protocol over alternative methodologies.

123 For interactive design much faster alternative methods are required.

124 test kits, underscoring the urgent need for alternative methods for rapid and accurate diagnosis of

125 ard (PCR, qPCR, RT-qPCR) methods, therefore, alternative methods have been reviewed.

126 loration and development of both classic and alternative methods of detecting biothreat agents.

127 ics and mathematical modeling, we develop an alternative model of scaling driven by feedback downregu

128 ster is a powerful system for characterizing alternative myosin isoforms and modeling muscle diseases

129 the intervention effects, while considering alternative network processes, such as reciprocity, tran

130 The presumption has been that alternative nitrogenases are fail-safe enzymes that are

131 Currently, there is only one alternative non-invasive system based on Optical coheren

132 te to pyruvate, the dimeric form of PKM2 has alternative, nonglycolysis functions as a transcriptiona

133 may eventually result in the development of alternative, novel treatments for corneal dystrophies, w

134 Here, we develop a simple method to test an alternative null hypothesis: that lineage-specific genes

135 pare a null hypothesis OS3 of 18% against an alternative of 43%.

136 mework, the available evidence and potential alternatives on how to establish tau positivity (T+) for

137 eins (AltProts) translated from nonannotated Alternative Open reading frame (AltORFs) were discovered

138 riptions omitted affected children receiving alternative or no treatment and some antidepressants can

139 that during cold conditioning, activation of alternative oxidase (AOX) occurs pre-climacterically.

140 que, there is a need to develop and validate alternative parameters to assess liver fat.

141 Alternative paths in a network play an important role in

142 Inhibition of the alternative pathway (AP) of complement by saliva from An

143 Alternative pathway (AP) regulatory factors were quantif

144 dy represents a potent inhibitor of both the alternative pathway and the terminal pathway, with possi

145 th its low expression and the presence of an alternative pathway for Ca(2+) uptake into photoreceptor

146 Kountz et al have discovered an alternative pathway for carnitine metabolism in the gut

147 ity adaptation, and furthermore, provides an alternative pathway to refine PC output.SIGNIFICANCE STA

148 s re-positioned themselves as negotiating an alternative perspective of normalcy in the stage from ab

149 We offer an alternative perspective: semantic space theory.

150 We introduce an alternative photosynthesis model (beta (PSII) model) inc

151 endosomes by causing increased binding to an alternative plasma membrane partner, ITSN1.

152 these systems, motivating the development of alternative platforms.

153 induction is evolutionarily conserved during alternative polarization of mouse and human macrophages.

154 Alternative polyadenylation (APA) contributes to transcr

155 Alternative splicing (AS) and alternative polyadenylation (APA) generate diverse trans

156 to study the impact of genetic variation on alternative polyadenylation (APA) in the nuclear and tot

157 usage, epigenetic factors potentially affect alternative polyadenylation (APA).

158 use of poly-beta-hydroxybutyrate (PHB) is an alternative polymer that can be considered environment f

159 scopy, autopsy), comparisons (world regions, alternative polyp definitions, adenoma), outcomes (preva

160 An alternative possibility, however, is that research data

161 ysiology and highlights how diverse roles of alternative protein isoforms can contribute to unique as

162 Recently, Alternative Proteins (AltProts) translated from nonannot

163 standards and summarizes the compendial and alternative rapid microbial test methods available for p

164 g their possible role as intermediates in an alternative reaction path.

165 zymes, including their structure, mechanism, alternative reactivity, and maturation.

166 onance (FO-SPR) technique is presented as an alternative readout for PCR utilizing NAzymes.

167 ad acquired resistance through engagement of alternative receptor tyrosine kinases either through upr

168 ed the LITAF-like protein CDIP1 as a second, alternative receptor.

169 ern the coupling of replication processes to alternative recognition-mediated reactivity modes.

170 on of resident epithelial cells is impaired, alternative regeneration mechanisms can occur.

171 mination have long been thought to represent alternative risk-spreading strategies, but current evide

172 ant cells use the extracellular matrix as an alternative route for cell-cell communication.

173 Here we present an alternative route to creating flat bands that does not i

174 ion of travel history data, but also suggest alternative routes of virus migration that are plausible

175 ivacaftor (17), requiring investigation into alternative routes.

176 en collection, then discuss self-collection, alternative sampling devices, and transport media.

177 ese NASAR mRNAs merit further development as alternative SARS-CoV-2 vaccines.

178 Although the PubMLST scheme outperformed the alternative scheme, the adh-1 locus must be retired from

179 e.g. the 5' miR-217 isomiR) are endowed with alternative seed sequences and share less than half of t

180 Alternative self-propagating protein states or strains g

181 This study reveals an alternative sequence for the synthesis of compounds that

182 ere consistent with the literature data, and alternatives showed similar sorption behavior as PFAAs.

183 Here, we show that the alternative sigma factor sigma(I) is essential in the ab

184 eports that suggest that GR expression is an alternative signaling mechanism that can bypass AR block

185 ting the activity of these enzymes, however, alternative solutions are required to avoid the side-eff

186 Therefore, alternative solutions to increase the quantity and quali

187 ory ossicles, we evaluate the ossicles as an alternative source of ancient DNA.

188 ns by superimposing stable isotope data from alternative sources to better estimate the success of na

189 Our results are robust to alternative specifications and variable definitions.

190 Alternative splicing (AS) and alternative polyadenylatio

191 udies led to the surprising observation that alternative splicing among single cells is highly variab

192 A response to cocaine and instead results in alternative splicing and chromatin accessibility events,

193 RBM10 also regulates alternative splicing and controls cancer cell proliferat

194 DAF-2B arises via alternative splicing and retains the extracellular ligan

195 Our data shed light on the relevance of p73 alternative splicing and show that the full-length C ter

196 RNA-seq datasets show a preponderance of 3' alternative splicing events in fam50a KO, suggesting a r

197 ll-length transcript analysis links multiple alternative splicing events together and allows for bett

198 study, we profiled gene expression changes, alternative splicing events, and DNA methylation pattern

199 increased awareness of the potential role of alternative splicing in the etiology of cancer.

200 ne the molecular mechanisms of cell-specific alternative splicing of a functionally validated exon in

201 experiments, we found that depending on the alternative splicing of exon 1, type I splice variants (

202 Alternative splicing of MOCS1 within exons 1 and 9 produ

203 We conclude that alternative splicing of MyD88 may provide a sensitive me

204 Alternative splicing of Shtn1 at the C terminus and down

205 ntly when O-GlcNAc levels are low, yet other alternative splicing pathways change minimally.

206 Alternative splicing regulates ECR conformation and rece

207 factor RELA to intragenic regions regulates alternative splicing upon NF-kappaB activation by the vi

208 This review focuses on alternative splicing, 3' end processing, miRNA-mediated

209 to the associations between gene expression, alternative splicing, and DNA methylation that may shape

210 te to this phenotype are observed, including alternative splicing, and mRNA expression levels of prot

211 and is associated with cis-acting elements, alternative splicing, and RNA-binding factors.

212 MBNL1, a protein involved in alternative splicing, is consistently overexpressed in M

213 , differential expression of isoforms due to alternative splicing, while the second major mechanism-R

214 althy individuals-especially with regards to alternative splicing-are lacking for most primary cell t

215 mediated changes to transcript abundance and alternative splicing.

216 dependence on pre-mRNA splicing and accurate alternative splicing.

217 tream and downstream of annotated ORFs, from alternative start sites nested within annotated ORFs and

218 DoseGAN was compared to alternative state-of-the-art dose prediction algorithms

219 bind to regulatory gene regions, an elegant alternative strategy employs small RNA guides, Piwi-inte

220 ut in addition may help provide a useful new alternative strategy to control ovarian tumor progressio

221 the predicted substrate 5-OHBza and with two alternative substrates, the MtCobT product 5-OHBza-RP an

222 are exclusively dependent on plant nectar or alternative sugar sources.

223 f gonorrhea cases expected under current and alternative surveillance strategies over a 50-year simul

224 Here, we report an alternative symmetry (P2) of the chemotaxis apparatus th

225 e characteristics that make them a promising alternative system for supplying several bioactive compo

226 ation by silver nanoparticles may provide an alternative technique for the development of other nanom

227 two extraction processes (an innovative and alternative technique, pressurized liquid extraction, an

228 e restricting the gene expression program of alternative Th fates.

229 interneurons may constitute a less invasive alternative than subthalamic stimulation.

230 c N(2) reduction to ammonia is an attractive alternative that can potentially enable ammonia synthesi

231 ing coupled with mass spectrometry offers an alternative that has seen increased use, especially in c

232 when making decisions between more than two alternatives, the decision-maker can even report a secon

233 Finally, alternative theranostic radionuclides and treatment stra

234 t disease phenotypes and provide avenues for alternative therapeutic approaches.

235 tion will be highlighted alongside potential alternative therapeutic options and their limitations.

236 rget is not easily achieved by all patients, alternative therapeutic options are currently being eval

237 interfering particles, which are an emerging alternative therapeutic.

238 by a set of standard chemotherapy drugs, and alternative therapies are used only when a patient has d

239 Considering the necessity of alternative therapies for this disease of high economic

240 mmunopharmacotherapy is being explored as an alternative therapy option and is based upon antibody-op

241 Ac]hu11B6-IgG(3) was a functionally enhanced alternative to [(225)Ac]hu11B6-IgG(1) but offered no imp

242 n, the BM chip may serve as a human-specific alternative to animal testing for the study of BM pathop

243 esting their utility as a minimally invasive alternative to biopsies for detecting disease biomarkers

244 luation of the R2* relaxation rate can be an alternative to biopsy for assessing LIC.

245 olved in arid environments as a water-saving alternative to C(3) photosynthesis.

246 g off-the-shelf and 3D-printable parts as an alternative to commercial devices.

247 y emerging technologies led to a sustainable alternative to control microorganisms.

248 MH can be an alternative to conventional pasteurization for OJMB proc

249 practice and could make for a cost-effective alternative to conventional stain-based protocols for st

250 ntial of IONPs to serve as safe and improved alternative to gadolinium-based chelates.

251 ablish lithium-ion substrates as a promising alternative to ILs for advanced thin-film devices.

252 her conservative management is an acceptable alternative to interventional management for uncomplicat

253 provides a rapid, accurate and reproducible alternative to labor intensive manual gating strategies.

254 We feel that the alternative to making these changes will lead to further

255 ymeric heart valves seem to be an attractive alternative to mechanical and biological prostheses as t

256 portending a potential avenue to develop an alternative to natural biomarkers.

257 UVV was demonstrated to be a cost-effective alternative to no vaccination.

258 low-voltage coagulation can be an effective alternative to other mechanical and thermal treatments f

259 nslational decay efficiency that could be an alternative to other methods to assess transcript transl

260 promising ecologically viable and renewable alternative to petroleum fuels, with the potential to re

261 rbon (M-N-C) catalysts as the most promising alternative to PGM catalysts.

262 viral particles/mL, making it an attractive alternative to RT-PCR assays.

263 n technical-reasoning skills is not the only alternative to social accounts; another possibility is t

264 itive conclusions about the use of MP, as an alternative to static CS.

265 valve implantation (TMVI) is emerging as an alternative to surgical mitral valve replacement in sele

266 ing Staphylococcus aureus Cas9 (SauCas9), an alternative to the most commonly used genome editing pro

267 rthermore, H1 provides a structural platform alternative to the native fold for RNase P to bind and m

268 n room as a fast, quantitative method, as an alternative to the qualitative and subjective pathologic

269 cine xenotransplantation-a long-investigated alternative to the scarce availability of human organs f

270 sible cell platform would be desirable as an alternative to the time-consuming purification of LCs fr

271 uminyls") have been reported, which offer an alternative to this textbook description: these reagents

272 ast few years as a computationally efficient alternative to time-consuming and computationally demand

273 support the use of the DNA-DGT sensor as an alternative to traditional sampling and analysis methods

274 erature indicators (TTIs), promised to be an alternative to unsatisfactory roasting temperature measu

275 elta T cells, and macrophages, are promising alternatives to alphabeta CAR-T adoptive therapy.

276 Benign selection agents serve as alternatives to antibiotics, which are costly and risk s

277 d extracellular matrix (ECM) technologies as alternatives to autogenous soft tissue grafts for period

278 d herein are viewed as promising sustainable alternatives to BPA and BPF.

279 l resistance has prompted the development of alternatives to combat bacterial infections.

280 r-based strategies have emerged as potential alternatives to conventional methods in miRNA quantifica

281 ation with membrane separation, eco-friendly alternatives to conventional procedures.

282 halide perovskites have emerged as promising alternatives to lead halide perovskites in optoelectroni

283 New atom-economical alternatives to Wittig chemistry are needed to construct

284 this method demonstrate its potential as an alternative tool for HIV screening during pregnancy.

285 n long-read sequencing solve inaccuracies in alternative transcript identification of full-length tra

286 Use of alternative transcription start sites located within the

287 's ability to accurately detect differential alternative transcriptional regulation events and associ

288 ation by OCM opens new avenues to understand alternative translation mechanisms involved in stress to

289 lasses of licensed antimicrobials, have made alternative treatment options for AMR pathogens increasi

290 Alternative tumour suppressor pathways need to be explor

291 zonic acid are efficiently prepared using an alternative two-step procedure and controlled hydrogenat

292 Coturnix coturnix japonica) is an attractive alternative, very similar to the chicken, but with the d

293 e improvements of our approach over existing alternatives via simulation as well as a previously publ

294 e used RNA mNGS to assess the frequencies of alternative viral infections in SARS-CoV-2 RT-PCR-negati

295 Single-nucleus RNA sequencing provides an alternative way to obtain transcriptome profiles of such

296 As an alternative, we sought to use deep learning (DL) for LV

297 The least hazardous of the considered alternatives were melamine and bis(2-ethylhexyl)-tetrabr

298 s from potato, pea, and grape seed as recent alternative, were compared to unfined control wines.

299 XR and a number of PFAS compounds, including alternatives whose activity on hPXR has not been experim

300 Pd-catalysts represent an appealing alternative, yet their use remains sparse due to undesir