ライフサイエンスコーパス: alveolar epithelium

1 y accounted for by greater protection of the alveolar epithelium.

2 drenergic receptor-cAMP signaling pathway in alveolar epithelium.

3 the formation and differentiation of mammary alveolar epithelium.

4 cular phenotype of type I pneumocytes of the alveolar epithelium.

5 tivation and inflammation along the delicate alveolar epithelium.

6 t IL-1beta may promote repair of the injured alveolar epithelium.

7 of local factors that cause apoptosis in the alveolar epithelium.

8 ed with transcripts located in bronchial and alveolar epithelium.

9 (2+)](i) increases and cPLA(2) activation in alveolar epithelium.

10 al Na+ flux and Na, K-ATPase function in rat alveolar epithelium.

11 ithelium yet robust staining was seen in the alveolar epithelium.

12 um transport and Na,K-ATPase function in the alveolar epithelium.

13 ic signaling plays a pivotal role in healthy alveolar epithelium.

14 r epithelium yet no staining was seen in the alveolar epithelium.

15 ction in the fluid transport capacity of the alveolar epithelium.

16 of P. carinii organisms aggregated along the alveolar epithelium.

17 e, pulmonary interstitium, and bronchial and alveolar epithelium.

18 e electrophysiologic properties of the human alveolar epithelium.

19 es the bioelectric barrier properties of the alveolar epithelium.

20 the existence of other water channels in the alveolar epithelium.

21 s, there was marked staining of hyperplastic alveolar epithelium.

22 ction, which contributed to the newly formed alveolar epithelium.

23 indicating a toxicological mechanism for the alveolar epithelium.

24 l steps of nanoparticle transcytosis through alveolar epithelium.

25 ized by infectious exacerbations and loss of alveolar epithelium.

26 acterizes the COPD GWAS gene ADGRG6 in human alveolar epithelium.

27 ms of injury to the lung endothelium and the alveolar epithelium.

28 ells (AT1s) during the repair of the damaged alveolar epithelium.

29 hat causes endocytosis of Na,K-ATPase by the alveolar epithelium.

30 depended on active ion transport across the alveolar epithelium.

31 on of hypoxia-inducible factor 1alpha in the alveolar epithelium.

32 the production of surfactant proteins in the alveolar epithelium.

33 murine model of RelA mutated throughout the alveolar epithelium.

34 within tracheal, bronchial, bronchiolar, and alveolar epithelium.

35 e mediators is selectively elaborated by the alveolar epithelium.

36 uired for wound repair and remodeling of the alveolar epithelium.

37 ch activated Notch1 was overexpressed in the alveolar epithelium.

38 fferences between the cells that make up the alveolar epithelium.

39 as enriched in the lung and localized to the alveolar epithelium.

40 onstitute approximately 60% of the pulmonary alveolar epithelium.

41 in (average 0.2 mum) liquid layer lining the alveolar epithelium.

42 imic the cellular heterogeneity in the human alveolar epithelium.

43 and secreted into the alveolar space by the alveolar epithelium.

44 vascular endothelium, plus CCR6 to traverse alveolar epithelium.

45 fluid reabsorption, via Na,K-ATPase, in the alveolar epithelium.

46 robably by downregulating Na,K-ATPase in the alveolar epithelium.

47 cell proliferation and decreased survival of alveolar epithelium.

48 se arising from impaired regeneration of the alveolar epithelium after injury.

49 d the normal fluid transport capacity of the alveolar epithelium after prolonged hemorrhagic shock, w

50 ation between the levels of 4-HNE adducts in alveolar epithelium, airway endothelium, and neutrophils

51 We conclude that injury to the alveolar epithelium allows the release of proinflammator

52 ht stimulate regeneration of the compromised alveolar epithelium, an etiology-defining event in sever

53 er-specific histone modifications in primary alveolar epithelium and A549 lung adenocarcinoma cells.

54 betaAR) regulate active Na+ transport in the alveolar epithelium and accelerate clearance of excess a

55 VID-19 characterized by direct injury of the alveolar epithelium and an impairment in its regeneratio

56 The effects of HCA on the alveolar epithelium and capillary endothelium are not we

57 ) are collectins expressed in the airway and alveolar epithelium and could have a role in the regulat

58 aracterized by apoptosis and necrosis of the alveolar epithelium and endothelium.

59 and up-regulation of Fas/FasL expression in alveolar epithelium and in infiltrating cells during the

60 growth factor expression by the bronchiolar-alveolar epithelium and lung macrophages.

61 We showed that AKAP13 is expressed in the alveolar epithelium and lymphoid follicles from patients

62 ticity is a temporally acquired trait of the alveolar epithelium and presents an alternative mode of

63 teric inhibitor enhanced regeneration of the alveolar epithelium and promoted accelerated recovery of

64 -directional transport of protein across the alveolar epithelium and restored alveolar fluid clearanc

65 lentivirus vectors for gene transfer to the alveolar epithelium and suggests that differences exist

66 w tidal volume ventilation protects both the alveolar epithelium and the endothelium in this model of

67 rting water across the apical surface of the alveolar epithelium and the epithelia of submucosal glan

68 The Na,K-ATPase has been localized to the alveolar epithelium and the importance of its role in co

69 in scleroderma lung tissue localized to the alveolar epithelium and the pulmonary interstitium which

70 events would affect the permeability of the alveolar epithelium and ultimately lead to epithelial ba

71 proliferation and differentiation of mammary alveolar epithelium and up-regulation of p21(WAF1) and p

72 ductance regulator (CFTR) ion channel in the alveolar epithelium, and airspace liquid absorption was

73 upregulation after injury, its induction by alveolar epithelium, and its release into both lumenal a

74 idirectional transport of protein across the alveolar epithelium, and restored alveolar liquid cleara

75 d-induced lung injury on the function of the alveolar epithelium, and secondly to determine whether p

76 endothelial cells, such as the bronchial and alveolar epithelium, and systemically by the excessive i

77 Na+ transport across the alveolar epithelium, and thus alveolar fluid resorption,

78 ffects of chronic alcohol abuse on the human alveolar epithelium are essentially unknown.

79 n vitro stretching experiments indicated the alveolar epithelium as the likely major source.

80 thelial alarmin, constitutively expressed in alveolar epithelium at steady state in both mice and hum

81 by a number of mechanisms (e.g., damage the alveolar epithelium, biotrauma).

82 are multipotent, generating both airway and alveolar epithelium, but are selective progenitors of al

83 at Mycobacterium tuberculosis penetrates the alveolar epithelium by downregulating its barrier proper

84 activation of TLRs and virus binding to the alveolar epithelium by resident constituents of the pulm

85 xpressing L188Q SFTPC exclusively in type II alveolar epithelium by using the Tet-On system.

86 The transfer of protective genes to the alveolar epithelium can attenuate lung injury if accompl

87 d, and their ability to transfect model lung alveolar epithelium cells in vitro was demonstrated.

88 (SARS-CoV-2) may induce a redox imbalance in alveolar epithelium cells, causing apoptosis, increased

89 Of the 14 claudins expressed by the alveolar epithelium, claudin-3, claudin-4, and claudin-1

90 The alveolar epithelium consists of type II cells, which sec

91 ed that overexpression of Na,K-ATPase in the alveolar epithelium could counterbalance these changes a

92 mmary glands exhibited a progressive loss of alveolar epithelium, culminating in lactation failure.

93 e niche, delaying repair and regeneration of alveolar epithelium during bacterial pneumonia.

94 med to determine the role of beta-catenin in alveolar epithelium during bleomycin-induced lung fibros

95 ls resulted in precocious differentiation of alveolar epithelium during pregnancy and the activation

96 resence resulted in the dedifferentiation of alveolar epithelium followed by a transdifferentiation i

97 tion of vectorial fluid transport across the alveolar epithelium following haemorrhagic shock is medi

98 res a normal fluid transport capacity of the alveolar epithelium following hemorrhagic shock by inhib

99 xchange, but a functional cell that protects alveolar epithelium from injury.

100 ugh the interaction of Pneumocystis with the alveolar epithelium has been well documented, very littl

101 uggest that compromising p53 function in the alveolar epithelium impairs recovery of the lung from bl

102 ng was increased in alveolar macrophages and alveolar epithelium in 95% O(2).

103 e other important functions in repair of the alveolar epithelium in acute lung injury (ALI).

104 force for reabsorption of water through the alveolar epithelium in addition to other ion channels su

105 However, the role of the alveolar epithelium in any of these pathogenic processes

106 ietic progenitor cells to regenerate injured alveolar epithelium in newborn mice.

107 structure and composition of the airway and alveolar epithelium in regions of fibrosis.

108 ASCs) that can contribute to both airway and alveolar epithelium in the distal murine lung.

109 res a normal fluid transport capacity of the alveolar epithelium in the early phase following haemorr

110 findings demonstrate a pivotal role for the alveolar epithelium in the maintenance of alveolar homeo

111 study was to investigate the function of the alveolar epithelium in the setting of reperfusion lung i

112 ving effects on injured lung endothelium and alveolar epithelium, including enhancing the resolution

113 ,K-ATPase subunit gene overexpression in the alveolar epithelium increases Na,K-ATPase function and l

114 ofluidic organ-on-a-chip lined by human lung alveolar epithelium interfaced with pulmonary endotheliu

115 ents in lung encounters serial barriers: the alveolar epithelium, interstitium, and capillary endothe

116 Injury to the alveolar epithelium is a critical event in ALI, and accu

117 The alveolar epithelium is a key regulator of the innate imm

118 T8-expressing aberrant basaloid cells in the alveolar epithelium is associated with impaired tissue r

119 thogenesis, in which recurrent injury to the alveolar epithelium is believed to drive aberrant wound

120 The alveolar epithelium is characteristically abnormal in fi

121 The alveolar epithelium is composed of alveolar type 1 (AT1)

122 The alveolar epithelium is composed of the flat type I cells

123 ary fibrosis, where repetitive injury to the alveolar epithelium is considered a key factor in pathog

124 Repair of the alveolar epithelium is critical for clinical recovery; h

125 Here, we show that collaboration with the alveolar epithelium is critical for controlling infectio

126 Therefore, the regenerative capacity of the alveolar epithelium is critical for recovery from these

127 Active re-absorption of Na+ across the alveolar epithelium is essential to maintain lung fluid

128 After birth, the alveolar epithelium is exposed to environmental pathogen

129 The absence of ex vivo models of human alveolar epithelium is hindering an understanding of cor

130 The alveolar epithelium is lined by surfactant, a lipoprotei

131 Improper regeneration of the alveolar epithelium is often associated with severe pulm

132 Injury to and/or dysfunction of the alveolar epithelium is strongly implicated in IPF diseas

133 These findings suggest that the alveolar epithelium is the primary target of Fas-mediate

134 ral infection from conducting airways to the alveolar epithelium is therefore a pivotal event in infl

135 Although commitment of the alveolar epithelium is unaffected, alpha-SMA+ mesenchyma

136 ch damage pulmonary vascular endothelium and alveolar epithelium, leads to alveolar oedema and pulmon

137 ate that the fluid transport capacity of the alveolar epithelium may be well preserved in the allogra

138 ator-induced nitric oxide (NO) production by alveolar epithelium may exceed that of other lung cell t

139 on, functional differentiation, and death of alveolar epithelium occur repeatedly with each pregnancy

140 energic receptor (beta2AR) function into the alveolar epithelium of beta1AR-/-/beta2AR-/- and beta1AR

141 Directed expression of TGFbeta3 in the alveolar epithelium of lactating mice using a beta-lacto

142 tein were constitutively expressed in normal alveolar epithelium of mice, and IL-10R were constitutiv

143 NA (adCFTR) to increase CFTR function in the alveolar epithelium of normal rats and mice.

144 beta(2)AR gene transfer to the alveolar epithelium of normal rats improved membrane-bou

145 ivary and lacrimal glands and is abundant in alveolar epithelium of the lung.

146 s, including heart, skeletal muscle, and the alveolar epithelium of the lung.

147 beta-catenin gene in differentiating mammary alveolar epithelium of the mouse results in the generati

148 well as gamma-GCS mRNA levels in airway and alveolar epithelium (p < 0.01).

149 otein-D, which is primarily localized to the alveolar epithelium plasma soluble receptor for advanced

150 Alveolar epithelium plays a pivotal role in protecting t

151 beta-Catenin in the alveolar epithelium protects against bleomycin-induced f

152 Progenitors of the alveolar epithelium remain largely mysterious, so the pr

153 physiological roles of AHR expressed in the alveolar epithelium remain unclear.

154 to organoids composed of organized airway or alveolar epithelium, respectively.

155 crobial factors, but fails to restore normal alveolar epithelium responsible for gas exchange.

156 eased proliferation and reduced apoptosis of alveolar epithelium, resulting in increased formation of

157 This highlights the alveolar epithelium's importance as a key signaling brid

158 Overexpression of a human beta2AR in the alveolar epithelium significantly increased AFC in norma

159 hat IL-10, constitutively produced by normal alveolar epithelium, stimulates signal transduction thro

160 itment maneuvers on the lung endothelium and alveolar epithelium, the net effect in clinical acute lu

161 actant production, type II cells protect the alveolar epithelium through increased expression of NRF2

162 r ability to protect the endothelium and the alveolar epithelium through multiple paracrine mechanism

163 d endogenous beta-catenin in differentiating alveolar epithelium through the deletion of exon 3 (amin

164 and Cl(-) transport occurs across the entire alveolar epithelium (TI and TII cells) rather than only

165 ologic concentrations of adenosine allow the alveolar epithelium to counterbalance active Na(+) absor

166 how Legionella-infected macrophages use the alveolar epithelium to metabolically process myeloid cel

167 The ability of the alveolar epithelium to prevent and resolve pulmonary ede

168 IL-1 induces the alveolar epithelium to produce granulocyte-macrophage co

169 trategies aimed at increasing the ability of alveolar epithelium to resorb the edema should lead to b

170 nsible for the shock-mediated failure of the alveolar epithelium to respond to catecholamines in rats

171 nsible for the shock-mediated failure of the alveolar epithelium to respond to catecholamines in rats

172 esized that FRH augments the response of the alveolar epithelium to TNF-alpha receptor family signali

173 e lung production of NO and a failure of the alveolar epithelium to up-regulate vectorial fluid trans

174 lecular characteristics of the healthy human alveolar epithelium, we have developed a new method to i

175 he role of beta-catenin signaling in mammary alveolar epithelium, we have stabilized endogenous beta-

176 expression becomes restricted to the distal alveolar epithelium whereas Foxp1 expression is observed

177 damage occurs primarily in distal airway and alveolar epithelium, whereas sFasL is present throughout

178 es are regulated by ion transport across the alveolar epithelium, which is composed of alveolar type

179 extracellularly in the hypophase lining the alveolar epithelium, which is highly enriched in lung su

180 ted suppression of NF-kappaB activity in the alveolar epithelium with a resultant increase in suscept

181 bility of the injured lung to repopulate the alveolar epithelium with functional cells.

182 at simulates the initial apical infection of alveolar epithelium with SARS-CoV-2 by using induced plu

183 gly, keratinizing squamous metaplasia of the alveolar epithelium with significantly increasing manife