ライフサイエンスコーパス: amenable

1 Fast-growing, genetically amenable, and stress-tolerant cyanobacteria are desirabl

2 via small interfering RNA (siRNA) may be an amenable approach for TNBC targeted treatment.

3 electrode deposition process makes them less amenable as low-cost and disposable components.

4 iption initiation in bacteria are especially amenable because the promoter recognition and melting st

5 arch due to its efficiency and utility under amenable BSL2 protocols.

6 rrent approaches, considerably extending the amenable coupling partners.

7 systemic infection model in the genetically amenable Drosophila melanogaster host, in which parasite

8 address this issue, we used the genetically amenable Drosophila pupal photoreceptor and follicular e

9 phila Efa6 in experimentally and genetically amenable fly neurons.

10 has a radiochemical and radionuclidic purity amenable for (132)La/(135)La-based cancer theranostic ap

11 The methodology was amenable for a multi-gram scale-up to deliver 2-alkyl-N-

12 The developed protocol is amenable for a scale-up reaction, and synthetic utility

13 acterized specificities to generate peptides amenable for identification by high-throughput tandem ma

14 These algorithms are amenable for incorporation into Earth System Models that

15 ell-free synthesis, although not practically amenable for large-scale enzyme production, provides a w

16 eurons harboring SOD1(G93A) is impaired, but amenable for pharmacological interventions aiming to acc

17 opump was 270 muL/min at only 10 V, which is amenable for POC applications with lower power consumpti

18 Therefore, the chicken embryo heart is amenable for study via the Langendorff preparation under

19 ted that the methodology described herein is amenable for the incorporation of biomolecules.

20 The formed ynones serve as precursors amenable for the synthesis of bioactive compounds.

21 crophage-dependent signaling cascade that is amenable for the treatment of gastric cancer.

22 closer to underlying neurobiology, are more amenable for uncovering links to genetics.

23 ck the potential of the PSC model to make it amenable for use with a broader range of assays and a gr

24 ffers a first-step towards a multi-factorial amenable IBD platform that could be scaled up to assess

25 Our results demonstrate a therapeutically amenable, KLF7-driven pathway that promotes PDAC growth

26 e performance of freezer-ready iNs in an HTS-amenable phenotypic assay that measured neurite outgrowt

27 In addition the extension of amenable substrates and the new product motifs that can

28 and function of human blood vessels and are amenable systems for modelling and identifying the regul

29 anobodies coupled to single-molecule imaging-amenable tags could allow superresolution analysis of en

30 ach that employed liquid chromatography (LC)-amenable thin-film microextraction (TFME) devices to fur

31 that, regardless of cause or context, may be amenable to "inflammo-stabilization." CSS research must

32 This radical-mediated process is amenable to a broad range of substrates and provides pro

33 The mild conditions are amenable to a diverse range of primary and secondary alk

34 The dearomatized products are amenable to a multitude of further derivatizations rangi

35 The disclosed method is amenable to a range of differentially substituted benzyl

36 nd the conditions proved to be mild and were amenable to a variety of functional groups.

37 positional analysis of an individual animal, amenable to a wide range of behavioral tasks.

38 tial results showed that this method is also amenable to access N-thioacyl sulfamates.

39 cost, high-reward educational outreach event amenable to all disciplines of science.

40 d by altered hemoglobin beta-chain synthesis amenable to allogeneic HSC transplantation and HSC gene

41 nerate large, multidimensional data that are amenable to analysis by new informatics approaches along

42 zymatic cleavage reactions in organelles are amenable to analysis by this new reporter strategy.

43 the methods, the general workflow should be amenable to analysis of other stereoisomers when two ste

44 may be detectable presymptomatically and be amenable to anti-inflammatory treatment.

45 aspects of the viral life cycle that may be amenable to antiviral targeting as well as key features

46 B (and standard N&B) MATLAB software package amenable to any standard confocal or TIRF microscope.

47 fy five source-specific chemical end-members amenable to apportionment.

48 d protein expression workflows and should be amenable to automation for accelerating enzyme screening

49 hodological instructions into discrete steps amenable to automation.

50 kground from the unchelated state, and to be amenable to barium sensing through fluorescence microsco

51 lt antibodies, including several that may be amenable to better vaccine responses.

52 docytidine (2'-AzCyd), a modified nucleoside amenable to bioorthogonal labeling with SPAAC chemistry.

53 eered biomaterial-based immunological niches amenable to biopsy to provide insights into the phenotyp

54 rchitectural distortions and asymmetries are amenable to biopsy with digital breast tomosynthesis-gui

55 This drug class is amenable to block-and-lock functional cure approaches, a

56 standard amniotic grafts and were therefore amenable to both running and interrupted 7-0 Vicryl sutu

57 om bioactive cyclization, a strategy that is amenable to broad application in pharmaceutical design.

58 of their underlying component parts, but is amenable to calculation.

59 uses, defined as those that are preventable, amenable to care, or both.

60 of RNA substrates under reaction conditions amenable to catalysis by the hairpin ribozyme.

61 vealed that the 3V wall is not static and is amenable to cell movements.

62 argement of the lysosome compartment that is amenable to cell sorting and pooled screens.

63 Phosphorylation makes cyclin L2 amenable to cellular degradation, leading to restriction

64 e tool to probe protein systems that are not amenable to characterization by x-ray crystallography, N

65 ffective alternative in cancers that are not amenable to checkpoint inhibitors or other immunotherapi

66 We also demonstrate that TWJ ligands are amenable to chemically induced synthetic lethality strat

67 d to virtually any integral membrane protein amenable to classic biophysical studies and for which a

68 les makes a key part of the noncoding genome amenable to clinical analysis.

69 ned workflows for high-throughput proteomics amenable to clinical applications.

70 f antiandrogen resistance in prostate cancer amenable to clinical testing using available targeted th

71 drugs were classified as non-dialyzable (not amenable to clinically significant removal by extracorpo

72 nsion over the course of a month and is also amenable to clonal analysis of HSC heterogeneity.

73 We show that all surface azide moieties are amenable to cluster-surface strain-promoted alkyne-azide

74 Identification of the subset of the proteome amenable to CMA degradation could further expand our und

75 at cognitive processing speed and memory are amenable to cognitive training interventions.

76 reference tables, for ease-of-use and to be amenable to computational applications.

77 zation step was shown to be a transformation amenable to continuous flow processing allowing for a dr

78 LSCs by PARP1 inhibition, which renders them amenable to control by NK cells in vivo.

79 are intracellular and are not enzymes per se amenable to conventional drug targeting.

80 utes to tackle complex diseases, not usually amenable to conventional vaccine strategies.

81 nts who had coronary artery disease that was amenable to coronary-artery bypass grafting (CABG) and w

82 ers (left intrahisian block), which was most amenable to corrective His bundle pacing by recruitment

83 ion and/or pulmonary hypertension may not be amenable to corrective repair.

84 These alloys are amenable to crack-free 3D printing via electron beam mel

85 p an expanded toolkit of autophagy reporters amenable to CRISPR/Cas9 screening.

86 was mainly slow growing pulmonary metastases amenable to curative resection.

87 inoma of the bladder, ureter, or urethra not amenable to curative surgery and not candidates for cisp

88 ctable hepatocellular carcinoma that was not amenable to curative treatment; no previous systemic tre

89 -printed parts and common hardware, which is amenable to deployment with microfluidic devices for poi

90 The model is amenable to detailed mathematical analysis and gives ins

91 cy, and storage, expressed as biomass), both amenable to detecting rapid ecosystem change.

92 g the capture antibody, the platform is also amenable to different biomarkers and may enable future d

93 tate electron density distributions are thus amenable to direct experimental observation.

94 As SpliMLiB beads are monoclonal, they were amenable to direct functional screening in water-in-oil

95 tibility of engineered RsRubisco, an isoform amenable to directed evolution.

96 nable to assay essential genes which are not amenable to disruption.

97 We show that this method is amenable to diverse proximity triggers and capable of re

98 h generates 3' terminal adducts that are not amenable to DNA repair and thus compromise genome stabil

99 cterization of pathogenic mechanisms and are amenable to drug tests.

100 l concentrations as low as ~10 cells/muL are amenable to effective trapping in the presence of an abu

101 Moreover, many species are not amenable to either large-scale sampling or laboratory cr

102 degenerative mitral regurgitation surgically amenable to either leaflet resection or preservation wer

103 y distribution are limited, our findings are amenable to experimental check and, moreover, suggest a

104 stasis and HSR, with functional consequences amenable to experimental evaluation.

105 a function of F between the 2 models may be amenable to experimental testing.

106 ries and superior mechanical properties, are amenable to exquisite strain manipulation with a broad t

107 es is challenging because they are often not amenable to extrinsic tags, are diverse in nature, and a

108 0 to 8.0, and wtPKM2 is optimally active and amenable to FBP-mediated allosteric regulation at pH(i)

109 This transformation was also found to be amenable to flow reaction conditions.

110 divergences or Precambrian spicules were not amenable to fossilization.

111 Thus, hPSC-derived tissues are amenable to functional improvement by circadian modulati

112 an allotrope of carbon with a planar surface amenable to functionalization and nanoscale dimensions t

113 Moreover, the dearomatized products are amenable to further elaborations, providing functionaliz

114 transwell migration assays and its design is amenable to future integration into multiplexed high-thr

115 rginine, as its N-acetyl isopropyl ester, is amenable to GC analysis using a 15 m midpolarity DB-35 c

116 ome signal loss, with fractions subsequently amenable to gene expression analysis and in vitro cell c

117 exhibited sufficient genetic variation to be amenable to genetic improvement with selective breeding

118 ferentiated cell types; they are thus highly amenable to genetic screens and to defining molecular co

119 the murine Gaa gene, this model is also not amenable to genome-editing based therapeutic approaches.

120 e head domain glycans, suggesting N2 is more amenable to glycan additions.

121 Both methods are amenable to gram-scale vinylstannane synthesis as well a

122 vide precision editing options in cell types amenable to HDR, especially when byproducts of DSBs must

123 public health policies and interventions or amenable to health care to create a list of avertable NC

124 e molecular subset of SCCs that are uniquely amenable to HER2 blocking therapies.

125 rogramming algorithm for RNA folding that is amenable to heuristics that make it run in O(n) time and

126 in microfluidic chambers of defined size are amenable to high resolution live imaging of their dynami

127 ing the binding of AZIN to antizyme that are amenable to high throughput screening.

128 TING as a powerful kinetic in vitro platform amenable to high throughput screens and as a broadly app

129 k in a unifying tool called SEPATH, which is amenable to high throughput sequencing studies across a

130 public policies and health interventions or amenable to high-quality health care-to assess trends at

131 of adhesion-associated factors and an assay amenable to high-throughput applications.

132 lly analyzed in a widely used format that is amenable to high-throughput applications.

133 is a powerful short-term transplant platform amenable to high-throughput drug screening studies, yet

134 ibute to the growing demand for technologies amenable to high-throughput phenotyping.

135 re either not commercially available or less amenable to high-throughput testing.

136 variational problem was recently shown to be amenable to highly efficient convex programming methods

137 This CarD FP assay is amenable to HTS and is an enabling tool for future novel

138 ontexture increases, new targets that may be amenable to imaging are being defined.

139 ulprit vessel if there was unstented segment amenable to imaging.

140 idity or functional limitations in cases not amenable to improvement with surgery.

141 to demonstrate that DNA oligonucleotides are amenable to in-solution HDX/MS in native conditions.

142 Our PCH architecture is amenable to industrial production as an intrinsic materi

143 and flexible scoring system is intuitive and amenable to integration for machine learning, network an

144 Our VCSEL biosensor is amenable to integration with miniaturized electronics, w

145 nd cellular recruitment in a system which is amenable to intervention for various studies in basic bi

146 anding of risk factors and pathways that are amenable to intervention is essential to decrease this u

147 However, mechanisms that may be amenable to intervention to reduce risk are unknown.

148 mes, and help distinguish frailty phenotypes amenable to intervention.

149 ife-sensitive periods are at least partially amenable to interventions later in life.

150 ese findings and assess pathways that may be amenable to interventions to ameliorate CM and SMA.

151 organ damage in situ requires animal models amenable to intravital imaging.

152 t, monolayer cell cultures, making the model amenable to investigate changes in nuclear mechanics due

153 The syntheses are amenable to large scale manufacturing.

154 eses are often long, complex, and not easily amenable to large-scale production.

155 ansions and urbanization as being especially amenable to large-scale spatial approaches.

156 acute necrotizing pancreatitis in cases not amenable to less invasive endoscopic and/or surgical pro

157 An asymmetric synthesis, amenable to library preparation of structurally diverse

158 Mild hepatic injury in this group may be amenable to lifestyle modifications.

159 and in GPR151-expressing cell lines that are amenable to ligand screens.

160 s the functions of HIV capsid protein and is amenable to long-acting therapy owing to its high potenc

161 with a manageable safety profile, making it amenable to long-term dosing in these patients.

162 Efficient spiral image acquisitions were amenable to low field strength and generated increased s

163 ulting in an unshielded PRC7 epitope that is amenable to mAb recognition upon renaturation.

164 naturally occurring regulatory systems more amenable to manipulation by removing or recoding their n

165 Some of these pathways are amenable to manipulation through dietary modifications o

166 within biological systems that aren't always amenable to many of the metrological concepts applied in

167 for intrinsic UV absorbance analysis and is amenable to medium throughput with the same constructs a

168 are present in adult melanomas and could be amenable to MEK inhibition.

169 ions of interfering molecules and is readily amenable to miniaturization by association with existing

170 red spin-photon interface, all in a material amenable to modern semiconductor fabrication.

171 but several distinct regions of the gRNA are amenable to modification.

172 encies (e.g., tens of Hz), thereby making it amenable to modulate sound and color simultaneously yet

173 The assay, which we show is amenable to multiplexed detection in a single lateral-fl

174 istidine in complex or heterogeneous systems amenable to neither solid-state nor solution NMR spectro

175 L(+) B-cell progenitor transformation and is amenable to non-tyrosine kinase inhibition.

176 oil exposure in caudal fin, a tissue that is amenable to nonlethal sampling.

177 graft-versus-host disease (GVHD) population amenable to novel, reduced-intensity treatments.

178 more, the resulting unsaturated products are amenable to numerous options for diversification.

179 Systemic free thiols are amenable to nutritional or therapeutic intervention.

180 eptor and antagonist/receptor binding and is amenable to optical, electrochemical, and mass-sensitive

181 bition potency and a pharmacokinetic profile amenable to oral dosing while controlling CYP450 and hER

182 gene-endowed targeting solutions that may be amenable to pathway amplification.

183 striction triad from the second pore is less amenable to perturbation than that of the first pore, su

184 es, which greatly expands the chemical space amenable to phage display.

185 nd can help to identify mechanistic pathways amenable to pharmacological intervention.

186 ns in tumor inflammation and immunity may be amenable to pharmacological manipulation and offer new c

187 uman neurodegenerative disease, which may be amenable to pharmacological therapies.

188 These pathophysiological pathways might be amenable to pharmacological therapy to reduce the risk o

189 tably applied to a broader range of diseases amenable to phenotypic drug discovery.

190 SCA3 phenotype in Drosophila was completely amenable to PNKP complementation.

191 laboratory chemistry analyzers that are not amenable to point-of-care analysis or home monitoring an

192 ad sequencing improves this issue, it is not amenable to precise quantitation, which limits its utili

193 es, identify additional patients potentially amenable to precision therapy.

194 ildren, and to calculate what proportion are amenable to precision therapy.

195 h among gynecological cancers, but is poorly amenable to preoperative diagnosis.

196 t difficult to predict and might be the most amenable to prevention strategies.

197 Asthma phenotypes are currently not amenable to primary prevention or early intervention bec

198 development for a variety of disease targets amenable to protein delivery and precise gene correction

199 developed to analyze this data require cells amenable to pseudo-time analysis or require datasets wit

200 e positives make the output of the algorithm amenable to quality control for verification.

201 iral propagation within cells previously not amenable to Raman microspectroscopic examination.

202 by developing a strain of influenza A virus amenable to rapid compositional characterization through

203 n centers in a way that is modular and thus, amenable to rapid diversity incorporation.

204 eir single-site nature they are usually only amenable to reactions that involve single molecules.

205 ndocrine cells are uniquely identifiable and amenable to recording as individual cultured neurons or

206 hydrazine and benzophenone, with the latter amenable to recycling.

207 gregations of sequelae that were selected as amenable to rehabilitation.

208 that can be delivered by inhalation and are amenable to relatively inexpensive large scale productio

209 oma (ASPS); measurable disease with one site amenable to repeated biopsies; an ECOG performance statu

210 have been considered for sepsis and might be amenable to repurposing for COVID-19.

211 or deep-seated soft-tissue malignancies not amenable to resection participated in a single-arm phase

212 tonation approach, but were shorter and more amenable to scale-up.

213 nt antibody types in serum and plasma and is amenable to scaling.

214 approximately 50%), indicating that patients amenable to second surgery do not represent a specific m

215 ctions in eukaryotic cells, while also being amenable to selective inhibition.

216 Fortunately, we found that PixJ crystals are amenable to serial femtosecond crystallography (SFX) ana

217 bacterial communities that are otherwise not amenable to single-cell analysis, such as natural microb

218 is thermally stable to 320 degrees C and is amenable to sintering into monolithic, polycrystalline d

219 promoter are transcriptional modulators and amenable to small molecule targeting.

220 in (LBD) of RORgammat was discovered that is amenable to small-molecule drug discovery.

221 own to be a transcriptional silencer that is amenable to small-molecule targeting for MYC suppression

222 se populations of sessile organisms that are amenable to spatial point process analyses, enabling inf

223 bgroups of patients with thyroid dysfunction amenable to specific preventive strategies and intervent

224 of anatase TiO(2) nanocrystallites, that are amenable to spectroscopic and electrochemical characteri

225 e reduced flavin as a co-substrate, are less amenable to spectroscopic investigation.

226 d properties of the occlusion unit, uniquely amenable to ssNMR, thus appears to be a key to explainin

227 l functions such as contractile force and be amenable to standard multiwell-plate manipulations.

228 in 6 patients with HER3-positive tumors not amenable to standard treatment.

229 nical specimens are not available in amounts amenable to standard workflows.

230 tate-space point-process models, making them amenable to statistical inference.

231 eta-analysis (all studies whose results were amenable to statistical pooling).

232 1-5 metastatic lesions, with all metastases amenable to stereotactic ablative radiotherapy (SABR).

233 plate dsDNA into a higher-ordered state less amenable to strand invasion by RAD51-coated ssDNA filame

234 adth of decision-process parameters that are amenable to strategic adjustment and the value in levera

235 us identify protein sequences that are more amenable to structural analysis.

236 in which particular homologs were unusually amenable to structure recovery in folding simulations co

237 sil deposits with well-preserved melanosomes amenable to studies of fossil colour and anatomy.

238 antation period of human development are not amenable to study in vivo.

239 uvium largely limited to smaller sand-bodies amenable to study in-situ by rovers.

240 Saccharomyces cerevisiae is amenable to studying membrane traffic by live-cell fluor

241 demonstrate that the collected fractions are amenable to subsequent DNA extraction, short tandem repe

242 ly applicable to cellular complexes that are amenable to subtomogram averaging.

243 etical, computer-generated materials will be amenable to successful experimental synthesis.

244 Even though both issues may be amenable to surgical management, combining lung transpla

245 ent option, especially in cases that are not amenable to surgical resection.

246 When hepatic recurrences after ALPPS was amenable to surgical/ablative treatment, median CSS was

247 tudy presented with gestational hypertension amenable to surveillance and timed delivery to improve o

248 Brains encode behaviors using neurons amenable to systematic classification by gene expression

249 ecently, there was no hornwort model species amenable to systematic experimental investigation, which

250 3A) receptor, we identify positions that are amenable to tagging with an environmentally sensitive re

251 errant tau in FTD patient-derived neurons is amenable to targeted degradation, representing an import

252 d ESCC cell model harboring a SMARCA4 allele amenable to targeted proteolysis and identify SMARCA4-de

253 Both mechanisms may be amenable to targeted treatment with existing drugs.

254 ry, we reveal an essential metabolic pathway amenable to targeting in NSCLC.

255 nching system can be extended to any analyte amenable to the detection with homogeneous sandwich assa

256 a sets within clinical microbiology that are amenable to the development of AI diagnostics include ge

257 rative, to utilize sampling methods that are amenable to the ESM approach.

258 of predicting AEs for 2-drug combinations is amenable to the Likelihood Ratio Test (LRT).

259 t also that the cyclization is efficient and amenable to the presence of a range of cycloalkenones an

260 ly predicting pyrimidines to be particularly amenable to the protocol.

261 he design combines various advantages: it is amenable to the same mathematical treatment as standard

262 This strategy is amenable to the stereocontrolled syntheses of trisacchar

263 onstationary isotope labeling approaches are amenable to the study of photoautotrophic and secondary

264 This new method is amenable to the synthesis of alternating diblock polymer

265 ring systems biology approaches particularly amenable to their interrogation.

266 m in disease, and reveals a molecular target amenable to therapeutic exploitation.

267 iptional networks leading to HF progression, amenable to therapeutic intervention in the adult heart.

268 pomorphic allele with a later disease onset, amenable to therapeutic intervention.

269 s of immunity and inflammation that might be amenable to therapeutic intervention.

270 data indicate that spinal cord microglia are amenable to therapeutic reprogramming via systemic manip

271 These receptors could be amenable to therapeutic targeting aimed at modulating T(

272 of ALX/FPR2 in revascularization that may be amenable to therapeutic targeting in diseases associated

273 ated pathways in AD pathogenesis that may be amenable to therapeutic targeting.

274 rations and altered pathways, including many amenable to therapeutic targeting.

275 pathobiologic pathway relevant to asthma and amenable to therapeutic targeting.

276 lated beta-catenin activity and which may be amenable to therapies that target these pathways.

277 d heterometallic titanium-organic frameworks amenable to these principles is relentlessly limited by

278 roves that quasi-2D sulvanite nanosheets are amenable to thin-film deposition and could show superior

279 bacterial genomes made them the first to be amenable to this approach but the sequences are availabl

280 s common classes of ligand could likewise be amenable to this approach.

281 4-amino-indoles are amenable to this process, with acyl group installation a

282 es, contain too many cysteine residues to be amenable to this strategy, and therefore there is tremen

283 c pulmonary hypertension (CTEPH) that is not amenable to thromboendarterectomy or is recurrent/persis

284 ency comb spectroscopy is shown to be highly amenable to time-resolved ATR-SEIRAS.

285 ion, however, may be detrimental, and agents amenable to tissue targeting for therapeutic application

286 column chromatography, render this reaction amenable to tonne-scale manufacturing.

287 e used with sedation in children who are not amenable to traditional imaging.

288 he reporting of overall survival in ways not amenable to traditional methods of meta-analysis, and vi

289 e evidence that DAAM2-associated SRNS may be amenable to treatment using actin regulating compounds.

290 c anhydrase inhibitor therapy and ultimately amenable to treatment with intravitreal anti-vascular en

291 l four cases, the anaphylaxis reactions were amenable to treatment with low-dose intravenous adrenali

292 lpha-heterosubstituted peroxy compounds, are amenable to useful synthetic elaboration.

293 The isolated Bcat products were amenable to various downstream functionalization reactio

294 ibly switchable fluorescent proteins (RSFPs) amenable to various nanoscopy schemes.

295 tionally simple under mild conditions and is amenable to various nucleophile classes, including azole

296 These compounds are amenable to various transformations including halogen ex

297 organism or in vitro culture system that is amenable to viral transduction to simultaneously profile

298 Pigment patterns in fish are among the most amenable traits for studying the cellular basis of adult

299 cells on the subminute time scale has become amenable using dynamic nuclear polarization-enhanced (13

300 es and fills in gaps in order to perceive an amenable version of reality.