ライフサイエンスコーパス: amine group

1 een the carboxyl group of 5caC and a primary amine group.

2 ing reaction to install an electron donating amine group.

3 rable to nucleophilic addition of a tethered amine group.

4 he 4-substituent of the pyrroline ring is an amine group.

5 ation of Asn 95 in recognizing the substrate amine group.

6 25, which is in close proximity to the alpha-amine group.

7 ar general base catalysis by the neighboring amine group.

8 how evidence of an equatorially coordinating amine group.

9 cytotoxin (TCT) without affecting a critical amine group.

10 int chirality in the vicinity of a secondary amine group.

11 umber of methyl substituents on the terminal amine group.

12 termediate is intramolecularly trapped by an amine group.

13 -trans-retinal by drugs containing a primary amine group.

14 n a single nanodrop solvates both protonated amine groups.

15 formation of urea linkages at the expense of amine groups.

16 , through reactions with its pendant primary amine groups.

17 fying other analytes containing free primary amine groups.

18 wer than that of the compounds with tertiary amine groups.

19 :1 relationship between bound Au complex and amine groups.

20 pH-dependent due to the protonation of their amine groups.

21 drolysis and amidization of surface-tethered amine groups.

22 ctionalized polystyrene beads having pendant amine groups.

23 ditionally acylated the C4' hydroxyl and C3' amine groups.

24 act as a bioisostere of hydroxyl, thiol, or amine groups.

25 ability of the amine and with the number of amine groups.

26 in films having varying densities of surface amine groups.

27 covalent cross-linking at both ammonium and amine groups.

28 sicles with excellent surface display of the amine groups.

29 ccharide, which may be due to the absence of amine groups.

30 H-bonding interactions between phosphate and amine groups.

31 as well as replacing the carboxylic acid and amine groups.

32 pling reagents and then reacted with protein amine groups.

33 -PS composite surfaces via their superficial amine groups.

34 The amine groups (0.285 mmol of amine per gram of functional

35 ponent bearing either a terminal amide or an amine group (40%) revealed analogous trends.

36 Additionally, the incorporation of amine groups allows covalent coupling of the QDs to the

37 methylene-4-nitrostyrene from amine group to amine group along oligoethyleneimine tracks up to eight

38 has a His-brace in which the His-1 terminal amine group also coordinates to a copper.

39 ugh ionic interaction if its N17' protonated amine group (an "address") with a nonconserved acidic re

40 ration transfer effect (GluCEST) between its amine group and bulk water, with potential for in vivo i

41 After the ITO surface functionalization with amine groups and covalently attached biotin, the device

42 soporous nanoparticles (MSNs) decorated with amine groups and loaded with liraglutide (LRT) for oral

43 is governed by interactions between specific amine groups and protein residues, and that this is not

44 -carbon chain triamine with terminal primary amine groups and replacement of the eighth methylene by

45 wn that apart from the nature and density of amine groups and the spatial separation of the acidic an

46 t pH 5.0 or 7.2 resulted in the oxidation of amine groups and, for collagen type II, the specific dec

47 9, with d9 indicating a deuterated trimethyl amine group) and meeting folate-intake recommendations.

48 ppositely charged paper (protonated tertiary amine groups) and the anionic groups of the reagents.

49 identified as a mixture of nitro, imine, and amine groups, and following reduction, there was suffici

50 was covalently bound to agarose via terminal amine groups, and the variables examined were GAG concen

51 er solubility of drugs containing a tertiary amine group are reported.

52 s suggest that the interactions at the alpha-amine group are stronger for full agonists such as gluta

53 so suggest that in biological mixtures where amine groups are abundant, the trapping of EPO-generated

54 n pH at the surface of the particles as free amine groups are generated.

55 raamide complexes with four appended primary amine groups are measured as a function of pH.

56 ded conformation in which the two protonated amine groups are solvated by a single water nanodrop.

57 zeolite frameworks doped with methylene and amine groups are studied using density functional theory

58 These amine groups are then converted to corresponding N-diaze

59 ity, large surface area and high fraction of amine groups as aptamer binding sites.

60 exclusive accessibility of nsPCR to primary amine groups, as demonstrated by its general applicabili

61 s containing either a carboxylic group or an amine group at the C-3 position were synthesized and cov

62 zeolites can accommodate both methylene and amine groups at high concentrations with minimal strain.

63 mong the best substrates, whereas those with amine groups at the 5-position were poor substrates.

64 Analogues with cyclic basic amine groups attached via ethoxy linkages at the C-8 pos

65 g the concentration of carboxylic groups and amine groups before and after membrane modification with

66 similar to that of thiophenol, aniline, and amine groups but not as that of hydroxyl.

67 from a tertiary to a secondary to a primary amine group, but that solvent insertion dominates in all

68 re they are commonly modified at their alpha-amine group by formylation or acetylation.

69 ilon-SUK containing both carboxylic acid and amine groups can be either protonated or deprotonated de

70 eakly acidic silanol/aluminol with secondary amine groups can mimic proline catalysts and are more ef

71 ependent from pH 8 to pH 4 (the pK(a) of the amine group conjugate acid).

72 These data showed that the four amine groups contribute significantly to proton-catalyze

73 the strength of the interaction at the alpha-amine group correlates with the extent of cleft closure

74 le (THCz) scaffold, containing two essential amine groups, displayed bactericidal activity against a

75 The N-terminus primary amine group does not make a significant contribution to

76 Materials functionalized with amine groups dominate this field, largely because of the

77 Protonation of amine groups doubles the strength of hydrophobic interac

78 nctionalization of the supports with primary amine groups either using an organosilane ((3-aminopropy

79 Within the secondary amine group, elevated adjusted odds ratios were observed

80 Past studies have focused on the free amine groups, especially those in amino acids, as HAN pr

81 ed polyethylene glycol (PEG) film containing amine groups, followed by the self-assembly of gold nano

82 The Pcs were functionalized with an amine group for covalent conjugation purposes and were d

83 ed by using electrochemical technique and an amine group for immobilizing biomolecules; thus, it is i

84 d the necessity of hydroxy quinoline and the amine group for La(3+) ion binding and the glyco-moiety

85 by alternate solvation of the two protonated amine groups for clusters with up to 10 water molecules.

86 ion, there was sufficient amounts of primary amine groups for covalent attachment of a polyethylene g

87 Furthermore, the reported affinity of amine groups for semiconducting SWNTs, as opposed to the

88 nal theory simulations confirmed the role of amine groups for stabilizing key intermediates through h

89 m tryptophan only in the absence of the free amine group, formed HANs at levels 57-76% of those by tr

90 L3), Leu267(7.32), and Ile274(7.39), and the amine group forms a hydrogen bond with the side chain of

91 Since the alpha-amine group forms bridging interactions at the cusp of t

92 in the presence or in the absence of primary amine group from aminophospholipids and amino acids.

93 ase activity is detected upon transfer of an amine group from an amino donor substrate to glyoxylate,

94 een carboxylic groups of rGO-Fc(COOH)(2) and amine groups from enzyme.

95 ffect that the degree of substitution of the amine group has on B-N bonding versus solvent insertion.

96 with different substitutions on the pendant amine groups have been synthesized (R = H (1), Me (2), a

97 alogues such as compound 13 containing basic amine groups have significantly increased PI3K inhibitor

98 s proton could be transferred to the leaving amine group, helping overcome a significant energy barri

99 ock copolymer bearing halogen bond-accepting amine groups, higher-order structures were obtained in b

100 After linking DNA to the amine groups, hybridization reactions with fluorescently

101 ses competitive hydrogen bonding between the amine groups (hydrogen-donor) and the phosphate/carbonyl

102 el 6-(difluoromethoxy)-2,5-dimethylpyridin-3-amine group in 19e contributed to the potency and improv

103 en-bonds between the phosphate group and the amine group in eggPE and LPE was observed with infrared

104 for late functional group conversion of a p-amine group in the peptides to the desired affinity labe

105 ous conditions show that the presence of one amine group in the second sphere leads to a cleavage of

106 ected as rapid selective acylation of the 2'-amine group in two sequence contexts.

107 They attack amine groups in amino acids, peptides and proteins to fo

108 ffinity to the donor groups (COO(-) and some amine groups in its deprotonated form, NH2) of cysteine

109 Covalent modification of primary amine groups in multiply protonated or deprotonated poly

110 y TL) is a metabolite of Hcy and reacts with amine groups in proteins to form stable amides, homocyst

111 tive ligands on surfaces by diluting surface amine groups in self-assembled and cross-linked monolaye

112 r interactions of zwitterionic phosphate and amine groups in sphingosine-1 phosphate (S1P) to conserv

113 In the presence of dCO2, the amine groups in the chitosan get protonated to convert n

114 e of both alkyl tails in the outer shell and amine groups in the core/inner shell.

115 The ability to covalently modify primary amine groups in the gas phase with N-hydroxysuccinimide

116 rought about by acylation of surface-exposed amine groups in the initial step of the bioconjugation p

117 otonated silicic acid and a polymer when the amine groups in the polymer are protonated.

118 dity than MOF-5, a likely consequence of the amine groups in the structure, although, in contrast to

119 Iron porphyrins with one or four tertiary amine groups in their second sphere are used to investig

120 reasing gradually as the density of terminal amine groups increases as a function of generation.

121 Trp(9)) of the linear peptide: their charged amine groups interact with acidic residues from TM2 and

122 thesis, methods that directly install a free amine group into C(sp(3))-H bonds remain unprecedented.

123 at it is carbamylated, since an unprotonated amine group is available to act as a Lewis base and form

124 Interestingly, although the amine group is buried in the hydrophobic core, the hydro

125 partial agonist kainate, in which the alpha-amine group is constrained in a pyrrolidine ring.

126 The amine group is found to substantially aid in the removal

127 rage parallel to the bilayer normal, and the amine group is oriented toward the headgroups of the lip

128 Geometrically similar diads in which one amine group is secondary, or both are secondary, are goo

129 structure-selective chemical reaction at 2'-amine groups is a robust technology for interrogating lo

130 ogel) pH sensor based on covalently attached amine groups is described.

131 Finally, the availability of the surface amine groups is further demonstrated by their reaction w

132 elix to show that an aligned pair of primary amine groups is uniquely competent to catalyze crossed a

133 This finding suggests that replacing an amine group (K side chain) with a primary amide group (Q

134 The Lys173 amine group lies just 6 A from the amine group of the co

135 A chlorine bleaching converted the amine groups located on the MOF linker to active N-chlor

136 ldehyde/acid, and by adduct formation at the amine group ( N-acylation with aldehydes and carboxylic

137 with the number of methylene groups between amine groups, [N-3-N-4-N] and [N-3-N-3-N], respectively.

138 functionalized with mixture of carboxyl and amine groups NDandante or amine NDamine, carboxyl NDvox

139 umidity, which facilitates formation of free amine groups needed for the initial reaction with dihydr

140 PS NP coated with primary amine groups (NH2) possessed positively charged surfaces

141 neither naphthalene-based modifiers without amine groups nor those with tertiary amine moieties are

142 hydrogenation catalysis, occurs through the amine group, not the aromatic ring as is widely believed

143 uggesting that 5MPCA modification by protein amine groups occurs in vivo.

144 Isopeptide bonds (IPBs)-formed between the amine group of a Lys residue and the carboxamide/carboxy

145 formed between a free, unprotonated, primary amine group of a lysine side chain in the peptide and th

146 The protonated amine group of AdoMet could provide a proton via a water

147 an acetyltransferase that blocks the primary amine group of amino acids on charged tRNA molecules, th

148 surface via cation exchange and the cationic amine group of an adjacent molecule.

149 oup of bestatin, which mimics the N-terminal amine group of an incoming peptide, binds to Zn2 with a

150 Locating the central amine group of desmethoxyverapamil near the selectivity

151 n abstraction of a proton from the substrate amine group of dimethylglycine prior to C-H bond breakag

152 kage between carboxylic acid group of HA and amine group of dopamine.

153 The simulations suggest that the amine group of GABA forms cation-pi interactions with Ty

154 red by conjugation to the free thiol and the amine group of gamma GSK, respectively, resulting in for

155 n H-bond between the N-3 of the 5'-C and the amine group of Gln-148.

156 ts was developed that react with the primary amine group of glycerophosphoethanolamine (PE) lipids to

157 carboxylate group of D23 and the side chain amine group of K28 that indicate salt bridge interaction

158 m, suggesting weak interactions at the alpha-amine group of kainate.

159 neral base to deprotonate either the epsilon-amine group of Lys-142 or to activate a water molecule a

160 The amine group of lysine can accept up to three methyl grou

161 e developed conditions to modify the epsilon-amine group of lysine in tryptic peptides with O-methyli

162 onventional antibody conjugation through the amine group of lysine or the thiol group of cysteine res

163 lic-acid group on SWNT-COOH and the terminal amine group of PA6.

164 he strength of the interactions at the alpha-amine group of the agonist with the protein in all but o

165 Additionally, the interactions at the alpha-amine group of the agonists have also been probed by stu

166 n ether (21C7 and 24C8 derivatives) over the amine group of the axle.

167 cal shifts, a pKa of 7.7 is measured for the amine group of the catalytic residue T1, confirming that

168 he Lys173 amine group lies just 6 A from the amine group of the conserved essential Lys92 side chain

169 Recent work suggests that the amine group of the GABA molecule may form a cation-pi bo

170 Our structures suggest that the amine group of the glmS ribozyme-bound coenzyme performs

171 nteraction of the protein with the aliphatic amine group of the ligand is very similar for the all of

172 or three (me3) methyl groups attached to the amine group of the lysine side chain.

173 ers an acyl chain from a phospholipid to the amine group of the N-terminal cysteine residue of the ap

174 s of the interactions between the N-terminus amine group of the peptide and several lipid atoms shows

175 substrate by hydrogen bonding to either the amine group of the peptide linkage or a backbone carbony

176 ity of a salt bridge between the sulfate and amine groups of 3-O-sulfoglucosamine is explored through

177 The interaction of both of the two amine groups of a diamine molecule with the sensor is es

178 ral different anionic species at the pyrrole amine groups of an oxoporphyrinogen unit within the supr

179 t, conventional conjugation methods that use amine groups of antibodies for covalent immobilization r

180 re the functionalization of the free primary amine groups of APLs using amine-reactive isotopic N,N-d

181 Imine bonds between primary amine groups of chitosan and carbonyl groups of antifung

182 ween the acetoacetate groups and the primary amine groups of chitosan, forming vinylogous urethane li

183 bonding between phospholipid head groups and amine groups of chitosan.

184 d C6 hydroxyl groups of alpha-mangostin with amine groups of different pKa values.

185 film by covalent bond formation between the amine groups of enzyme or NAD(+) and the carboxylic acid

186 the first direct NMR characterization of the amine groups of glucosamine and 3-O-sulfoglucosamine in

187 d by hydrogen bonds between the carboxyl and amine groups of glycine molecules.

188 ction of nitrated AuNPs@4-HTP((ox)) with the amine groups of NEDa, the fluorescence of NEDa was quenc

189 of the dendron derivatives to the peripheral amine groups of PAMAM followed by reduction.

190 ith antibodies (taking advantage of the many amine groups of PANI).

191 imidate, which can form a covalent bond with amine groups of proteins.

192 icles together with the high affinity of the amine groups of the analyte for the nanoparticle surface

193 ylic groups of the 4-carboxyphenyl layer and amine groups of the antibody.

194 ps on the polymer and the positively charged amine groups of the drugs.

195 etween the carboxylic acid and an accessible amine groups of the functional molecule.

196 In the formed complex, the charged amine groups of the polycation mainly interact with DNA

197 The amine groups of the stationary phase determine the charg

198 xysuccinimide and simultaneous coupling with amine groups of two growing peptide chains, with excelle

199 A subgroup of HIPs, in which N-terminal amine groups of various peptides are linked to aspartic

200 feature is the incorporation of a secondary amine group, offering unique tight hydrogen-bonding capa

201 or untargeted chiral metabolomics of hydroxy/amine groups (-OH/-NH(2)) containing metabolites, includ

202 by two carboxylic acid groups and the single amine group on an appended side chain of GdL(1) and form

203 yze a condensation reaction between the free amine group on lysine and the BHB carboxylic acid, there

204 l substrate, L,L-SDAP, by the absence of the amine group on the amino acid side chain.

205 of the band at 1529 nm, which is due to the amine group on the beads, or the increase of the amide b

206 We found that an amine group on the side chain of this residue is necessa

207 ted with the remaining primary and secondary amine groups on PEI to afford anionic functionalities.

208 ly 682+/-5 ns) dye was covalently coupled to amine groups on the 800 nm diameter silica spheres in or

209 n the carboxyl groups on the CNT surface and amine groups on the detection DNA probes.

210 Next, the amine groups on the graphene surface were activated usin

211 tion of carboxylic groups and an increase in amine groups on the membrane active layer, consistent wi

212 lable reagent, acetaldehyde-d4, to label the amine groups on the monoamines via reductive amination.

213 determined that the added steric bulk of the amine groups on the P2N2 ligands hinders catalysis and t

214 dy reveals the clean deamination of terminal amine groups on the particle surfaces by NO, exemplifyin

215 acetylene than ethylene while the functional amine groups on the pore/cage surfaces further enforce t

216 Hyaluronic acid is covalently linked to amine groups on the surface of these plates by 1-ethyl-3

217 Subsequent covalent crosslinking with amine groups on the tissue surface further improves the

218 formed by nucleophilic attack of either the amine group or the sulfhydryl group of the substrate on

219 ructural features, such as the nature of the amine group or the terminal part of the fatty acid.

220 ecule contact, including possible effects of amine group oxidation and molecular conformation.

221 nanofiber sheets are decorated with primary amine groups, permitting covalent functionalization of t

222 (trans) of 2.6 and 3.1, and of the enalapril amine group, pK(cis) and pK(trans) of 5.9 and 5.6.

223 AMACE1 was coupled via its primary amine group (pKa 8.2) under aqueous conditions to four m

224 ffective antagonists had a partially charged amine group predicted to penetrate the channel pore, ant

225 In contrast, blocking free amine groups preexisting in the stroma with acetic anhyd

226 / N-hydroxysuccinimide (EDC/NHS) between the amine group present in the probe and carboxylic groups p

227 esidues present on the enzyme periphery with amine groups present on a novel redox polymer, poly[viny

228 e aldehyde groups of BNPs, which can bind to amine groups present within lesional skin, leading to lo

229 ng hydrogen bonding between the carbonyl and amine groups present within the monolayer structure.

230 t His-225, in deprotonation of the substrate amine group prior to FAD reduction.

231 neutral or charged (alkylammonium siloxides) amine groups, prior to CO(2) adsorption, is also address

232 eared to prevent adhesion, whereas secondary amine groups promoted adhesion, in agreement with previo

233 n was exothermic, presumably because of DOPE amine group protonation.

234 ons impart interdroplet adherence, while the amine groups provide access to pH-triggered coalescence.

235 At low pH, which protonates the LY97241 amine group, recovery from block at hyperpolarized poten

236 e-wide transcriptome analysis shows that the amine groups reduce the perturbations caused by GO on ce

237 H(3)) incorporating 61.44 molecules/nm(2) of amine groups, resulting in a positively charged zeta pot

238 ral to proton-coupled transport and that the amine group serves the same functional role as the Na2 i

239 In addition, computations indicate that the amine groups shift their pKa values due to the confined

240 nsubstituted willardiines with primary alpha-amine groups similar to that of the full agonist glutama

241 For BA with more than two amine groups (spermine, spermidine), the removal rate wa

242 istribution in DPPE molecules shows that the amine groups strongly interact with the phosphate and ca

243 ased on polymers containing simple aliphatic amine groups substantially reduce the work function of c

244 containing a thiol, a thioether, or an extra amine group such as arginine, cysteine, lysine, methioni

245 hocking of the methane-rich mixture produced amine groups, suggesting the possible synthesis of amino

246 Binding of AuCl(4)(-) to amine groups tethered to the interior of a 2 nm siloxane

247 c compounds of environmental concern contain amine groups that are positively charged at environmenta

248 and direct methods to convert C-H bonds into amine groups that are prevalent in many commodity chemic

249 ic homo- and copolymers containing secondary amine groups that can be converted into nitric oxide (NO

250 a pocket of the appropriate size bordered by amine groups that could aid in the binding of DDT throug

251 ganic framework functionalized with tertiary amine groups that exhibits high capacities for radioacti

252 ael-retro-Michael reactions between adjacent amine groups that move it up and down the track.

253 substrates, producing a homogeneous layer of amine groups that serve as sites for DNA attachment.

254 ompounds with hydrocarbon ester and tertiary amine groups, the bulk polymer itself is elastomeric and

255 ate HAAs by N-hydroxylation of the exocyclic amine group; the resultant N-hydroxy-HAA metabolites for

256 o an intermediate bearing a fluorochrome and amine groups, then reacted with either HIV-Tat peptide o

257 n sponge effect" associated with multivalent amine groups, this class of ligand-exchanged QDs is able

258 Covalent binding via reaction of one amine group to a boron-doped, smooth Si-Cl substrate is

259 ation of alpha-methylene-4-nitrostyrene from amine group to amine group along oligoethyleneimine trac

260 of DNA oligonucleotides carrying a catalytic amine group to effect the aqueous S(N)Ar arylation of 2'

261 The succinimide ester group reacts with the amine group to initiate antibody surface immobilization,

262 e compounds exploit their positively-charged amine group to mimic the carbocationic sterol intermedia

263 Intramolecular H transfer from the amine group to one of the two O atoms in the nitro group

264 c activation by N-oxidation of the exocyclic amine group to produce N-hydroxylated metabolites, which

265 provides a surface that readily reacts with amine groups to allow covalent immobilization of antibod

266 Inhibitors require at least two amine groups to be effective.

267 c alkylation of a polymeric scaffold bearing amine groups to give synzymes that catalyze the Kemp eli

268 ing agent, to convert polymer-bound tertiary amine groups to less chloramine-reactive quaternary ammo

269 These capsules were decorated with amine groups to present a positively charged outer coron

270 inding and to a lowered pK(a) of a substrate amine group upon binding P450 2D6.

271 ical peptide labels that are coupled to free amine groups usually after protein digestion to enable t

272 against S. pyogenes were conjugated to Ptyr amine group via biotin-NeutrAvidin coupling.

273 factors is transformation of a nitro into an amine group via reduction with a low-valent titanium in

274 g of the crowded substitution at the central amine group was found to be the reason for the presence

275 late via cleavage of a carbamate linkage, an amine group was left that provided an attachment site fo

276 er functionalization with multiple azide and amine groups was achieved without degradation of the ket

277 Methylation of the amine groups was not found to prevent the reaction betwe

278 The hydroxyalkylammonium-(amine) group was introduced at the 5' position of the 2'

279 ted with vitamin B(6), which lacks a primary amine group, was variable at this pH.

280 inating in a reactive carboxylate, ester, or amine group were full, potent human A(3)AR agonists.

281 ylation, N-methylation, and attachment of an amine group were identified in zebrafish embryos.

282 that two primary and at least one secondary amine group were required.

283 Different primary amine groups were found to be (potential) labeling sites

284 thalic acid) with 2-amino terephthalic acid, amine groups were incorporated into the framework to pro

285 OSCs with primary amine groups were reacted with isotopic formaldehydes to

286 When primary amine groups were reintroduced by azide-alkyne coupling,

287 trostatic interactions provided by secondary amine groups were sufficient to capture PFAS with higher

288 onfirmed the surface modification of CNTs by amine groups, whereas dynamic light scattering establish

289 zed via click chemistry, and the other is an amine group which can also be functionalized by classic

290 e disulfide bridge and provided the terminal amine group, which facilitates addition of a cross-linke

291 The degree of site-isolation of the amine groups, which affect the material's catalytic prop

292 he stable and complete modification of these amine groups, which can be reversible upon the addition

293 o functionalize the treated surfaces to form amine groups, which were further activated with glutaral

294 p produced amphiphilic polymers with pendant amine groups, which, at pH ~5, adopted an intrachain H-b

295 also for cyclic sulfamidates bearing a free amine group, while other strategies failed to achieve a

296 relative position of the internal secondary amine group with respect to the terminal groups.

297 First, interaction of an inhibitor's amine group with the conserved active-site Asp is essent

298 Reaction of amine groups with activated esters would be catalyzed by

299 rom specific interactions of the amidine and amine groups with the active-site residues of trypsin an

300 It reveals the carboxyl and amine groups would heal charged defects via electrostati