ライフサイエンスコーパス: amino acid sequence

1 oop of approximately 20 residues in the ExoU amino acid sequence.

2 roups according to substrate specificity and amino acid sequence.

3 r self-reaction depending on position in the amino acid sequence.

4 hat influence gene regulation in addition to amino acid sequence.

5 ricted to protein solubility prediction from amino acid sequence.

6 , but are otherwise unrelated in topology or amino acid sequence.

7 phase behavior of an IDP is sensitive to its amino acid sequence.

8 a-helical bundles of peptides with a similar amino acid sequence.

9 constructs by deleting large segments of its amino acid sequence.

10 site that may be remote from one another in amino acid sequence.

11 nate recognition sites, while preserving the amino acid sequence.

12 ecular weight incongruent with the predicted amino acid sequence.

13 ophilic characteristics without changing the amino acid sequence.

14 andemly repeating units of a conserved seven-amino acid sequence.

15 which is determined by the protein's primary amino acid sequence.

16 amily despite notable differences in primary amino acid sequence.

17 l properties of the isomers sharing the same amino acid sequence.

18 as GLP-1 and was abolished by scrambling its amino acid sequence.

19 by the viral nucleotide sequence but not the amino acid sequence.

20 t degeneration of their functionally optimal amino acid sequence.

21 mplest all-beta fold strongly depends on the amino acid sequence.

22 vo gene creation within a strongly conserved amino-acid sequence.

23 by replacing 61 amino acids with a novel 91-amino-acid sequence.

24 ction for many disordered regions from their amino acid sequences.

25 of AM2-TM, despite their markedly different amino acid sequences.

26 ochemical and structural properties of their amino acid sequences.

27 mRNA translation decodes nucleotide into amino acid sequences.

28 PKS-NRPS docking motifs possessing identical amino acid sequences.

29 ifferent enzyme kinetic profiles and primary amino acid sequences.

30 ely, which differ solely in their N-terminal amino acid sequences.

31 proteins as well as dissimilarities in their amino acid sequences.

32 ome without changing overall codon usage and amino acid sequences.

33 ional ensembles of IDPs are encoded by their amino acid sequences.

34 f which are interspersed with highly charged amino acid sequences.

35 well conserved despite overall divergence of amino acid sequences.

36 nd implement four novel types of padding the amino acid sequences.

37 borate gating structure as programmed by the amino acid sequences.

38 permus and used tandem MS to determine their amino acid sequences.

39 map-guided structure modeling starting from amino acid sequences.

40 s for photopigments derived from Rh1 and Rh2 amino acid sequences.

41 f structures, physicochemical properties and amino acid sequences.

42 hree-dimensional shape of a protein from its amino acid sequence(1).

43 kDa and 141 kDa) than expected based on the amino acid sequence (12 kDa, 24 kDa and 37 kDa, respecti

44 lls, indicated that residues at the edges of amino acid sequence 138-168 invoke intracellular localiz

45 he intracellular retention is present within amino acid sequence 138-168 of TMC1 N-terminus.

46 onoclonal antibodies raised against a P2X(7) amino acid sequence (200-216), whose conformation is dis

47 uberosum (potato) genome using phylogenetic, amino acid sequence, 3-D protein modeling, and gene stru

48 x (PSSM) of proteins, those derived from the amino-acid sequence (AAS), various matrix representation

49 We also provided the fusion transcript and amino acid sequences according to multiple breakpoints a

50 but it is also nearly 100% identical in its amino acid sequence across all sampled genomes.

51 p41 membrane-proximal external region (MPER) amino acid sequences across HIV-1 clades and the ability

52 TNC-C binding PL3 peptide (amino acid sequence: AGRGRLVR) was identified by in vitr

53 y-restricted presentation of a modified AIP1 amino acid sequence (AIP1S).

54 Amino acid sequence alignments between bVP24 and eVP24 a

55 that would be impossible to predict from the amino acid sequence alone.

56 Inputting the amino acid sequences alone, we further generated membran

57 Furthermore, by controlling the amino acid sequence along the bundlemer periphery, we us

58 verse molecules and what variations in their amino acid sequence alter their substrate selectivity?

59 ffect predictor (VEP) plugin, COCOS captures amino acid sequence alterations stemming from variants t

60 The only essential input is amino acid sequence, although available structural infor

61 efined by differences in donor-recipient HLA amino-acid sequence (amino-acid mismatch score, AMS; and

62 tand this specificity, we performed detailed amino acid sequence analyses and investigated the cataly

63 Through amino acid sequence analysis of S proteins of representa

64 context of NHFe(2) chemistry, provided by an amino acid sequence analysis through the families of the

65 ss spectrometry, lipoprotein reconstitution, amino acid sequence analysis, and molecular dynamics sim

66 bitor enzyme kinetics (Km and IC50), (2) its amino acid sequence and (3) its ability to activate calc

67 mplex, an all-atoms model is built using the amino acid sequence and a known structure of a related c

68 To examine the relationship between amino acid sequence and aggregation propensity, we made

69 an be substantially increased by varying its amino acid sequence and by this, serve as a starting poi

70 aK-the bacterial Hsp70-but both are based on amino acid sequence and energy calculations of qualitati

71 R-pMHC modelling pipeline takes as input the amino acid sequence and generates models of the TCR-pMHC

72 in PilA, the major protein subunit, both in amino acid sequence and in glycosylation patterns.

73 tative set of proteins/peptides with diverse amino acid sequence and length.

74 of NMR in establishing the relations between amino acid sequence and phase-separation propensity.

75 Amino acid sequence and predicted structural similarity

76 The precise amino acid sequence and prenyl group define a combinator

77 are powerful approaches for mapping both the amino acid sequence and PTMs; one of these techniques is

78 chnologies, the relation between a peptide's amino acid sequence and S/N remains largely nonquantitat

79 ese molecules and investigate the effects of amino acid sequence and sulfation modifications on throm

80 mycobacteria are evolutionarily unrelated in amino acid sequence and three-dimensional structure to t

81 atures obtained from InterPro, UniProtKB and amino acid sequences and show that this method improves

82 3a, respectively, and translated these into amino acid sequences and used for genotype variation ana

83 complementarity-determining region (CDR-L3) amino acid sequences and/or Vkappa,lambda-Jkappa,lambda

84 ve molecular mass of 50 kDa, as predicted by amino acid sequencing and mass analysis, confirming that

85 ted with sequence data types (nucleotide vs. amino acid sequences) and with different methods of phyl

86 served motifs in a particular order in their amino acid sequence, and are referred to as class beta M

87 ine learning to predict peptide S/N based on amino acid sequence, and identify specific physical prop

88 n all-atom 3D simulations of keratin primary amino acid sequences, and tyrosine phosphorylation predi

89 Thus, O-glycosylation, not amino acid sequence, appears to be the major factor gove

90 he intrinsic exchange rates derived from the amino acid sequence are not appropriate reference values

91 sequences and protein information, including amino acid sequences, are included.

92 and imaged using AuNS with the high-affinity amino acid sequence arginine-glycine-aspartic acid-pheny

93 diction of solubility that requires only the amino acid sequence as input.

94 The use of raw amino acid sequences as input for deep learning models f

95 that comprises two repeats of a canonical 18 amino acid sequence associated with straight alpha-helic

96 he CROP domain of TcdA centered on identical amino acid sequences at residues 2162-2189 and 2410-2437

97 udy was to improve the alignment between the amino acid sequences attached to the upper and lower aro

98 The amino acid sequence based predicted three dimensional (3

99 ied to cause polymorphism, but the intrinsic amino acid sequence basis for this polymorphism has been

100 Ten and 16 amino acid sequences, bearing a core of six and 12 rando

101 At the level of entry, differences in the amino acid sequences between the human and mouse ortholo

102 gnature of eukaryotic alphaHDPs derived from amino acid sequence, biochemical, and three-dimensional

103 clic peptide chemotype space not only at the amino acid sequence but also at the ring-forming moiety.

104 mRNAs with changed codon bias have the same amino acid sequence but attain different conformations,

105 AAVrh.10 and AAVrh.39 are 98% identical in amino acid sequence but only ~93.5% identical to AAV8.

106 that TPT recognition and binding depended on amino acid sequences but not on secondary, tertiary or q

107 e a panel of chimeric viruses with identical amino acid sequences but nucleotide sequences derived fr

108 pared the folding of proteins with different amino acid sequences but the same basic structure, or fo

109 actin are nearly indistinguishable in their amino acid sequence, but are encoded by different genes

110 The fold of a protein is encoded by its amino acid sequence, but how complex multimeric proteins

111 tated peptide peaks with their corresponding amino acid sequence by database search and subsequent MA

112 y (MALDI-TOF) and the determination of their amino acid sequences by electrospray ionisation mass spe

113 ines that seek the identification of peptide amino acid sequences by matching experimental tandem mas

114 he two copies of H2A are nearly identical in amino acid sequence, CAG repeat stability depends on H2A

115 'D3 domain through a relatively unstructured amino acid sequence, called here the N-terminal linker.

116 ied eukaryotes possess a tandemly repeated 7-amino-acid sequence, called the canonical CTD, which orc

117 sage 11 or 12 (P11/P12) had no nucleotide or amino acid sequence changes from the original virus in s

118 mer using biophysicochemical features of its amino acid sequence combined with quantification of 4-me

119 their 3D protein structure as well as their amino acid sequence compared with a data set of known pr

120 sically disordered regions (IDRs) having low amino acid sequence complexity.

121 ased on differences in gene neighborhood and amino acid sequence conservation and present the crystal

122 ces that are subject to GC usage and primary amino acid sequence constraints.

123 ost's glycosylation machinery, and, if their amino acid sequences contain consensus sequons for N-lin

124 ic, cation-pai, and aromatic interactions in amino acid sequence-dependent LLPS.

125 measurement of their masses and independent amino acid sequence determination by tandem MS, allowing

126 ges at the six positions in which the target amino acid sequence differed.

127 We hypothesized that amino acid sequence differences between rod- and cone-sp

128 Mapping of isoform amino acid sequence differences for SK2 onto the recentl

129 ctural similarities, despite sometimes large amino acid sequence differences.

130 Significant amino acid sequence divergence among these AID orthologs

131 alpha-helices positioned in membranes; (iv) amino acid sequences, domain architecture, functional an

132 links messenger RNA nucleotide sequence with amino acid sequence during protein synthesis.

133 d to craft a folded protein structure and an amino acid sequence encoding that structure.

134 We introduce a model of amino acid sequence evolution that accounts for the stat

135 he NCoR/SMRT complex, by removing almost all amino-acid sequences except the methyl-CpG binding and N

136 apus reveals that DGAT2 enzymes with similar amino acid sequences exhibit starkly contrasting acyl-do

137 all accessions and are the most conserved in amino acid sequence for most accessions.

138 ugh the identification of an archaic-derived amino acid sequence for the collagen type X, alpha-1 (CO

139 There are 20(200) possible amino-acid sequences for a 200-residue protein, of which

140 imized Likelihood estimate of immunoGlobulin Amino-acid sequences), for calculating the probability o

141 ple biophysical metrics of "developability." Amino acid sequences from 137 antibodies in advanced cli

142 Therapeutic peptides are short amino acid sequences (generally considered <50 amino aci

143 EigenTHREADER takes a query amino acid sequence, generates a map of intra-residue co

144 ich, by definition, do not alter the primary amino acid sequence, have no effect on protein structure

145 pical activator of Cdk1 and Cdk2 that has no amino acid sequence homology to cyclins, are sterile and

146 complex with the ability to scan and compare amino acid sequence identities of bound class I and II p

147 fied an Mtb protein (PPE15) that showed weak amino acid sequence identities with mammalian perilipin-

148 P11B1 is unavailable and the enzyme has high amino acid sequence identity (93%) to a closely related

149 Functional complementation correlates with amino acid sequence identity between orthologs, but vari

150 proteins also display extreme divergence in amino acid sequence identity between STs (i.e., 59%-61%

151 urface antigens of G. lamblia that show >90% amino acid sequence identity between the two human-patho

152 s ten genes coding for proteins sharing high amino acid sequence identity with members of the Ros/Muc

153 Specificity was defined by 100% amino acid sequence identity with tick-borne pathogen pr

154 Despite only 57% amino acid sequence identity, the Ab from a MARV-naive d

155 Even though both proteins share about 90% amino acid sequence identity, they exhibit different ope

156 MT1-5 and encoding polypeptides sharing >40% amino acid sequence identity, were expressed in Escheric

157 to that of TSP1, consistent with their high amino acid sequence identity.

158 in domain organization they display just 31% amino acid sequence identity.

159 ntain the DCCL-conserved motif but share low amino acid sequence identity.

160 The encoded proteins share ~85% amino acid sequence identity.

161 In contrast, deletions that included an 80-amino-acid sequence immediately downstream resulted in h

162 alizes on a highly conserved Asp-Ser-Leu-Asp amino acid sequence in ACPs to which acyl groups attach.

163 of the NLGN family and consists of a unique amino acid sequence in humans that is not evolutionarily

164 n at multiple sites along the spectrin-betaV amino acid sequence in the lineage leading to mammals, t

165 s of decoy peptides derived from the primary amino acid sequence in the SOD2-binding site in hsp70.

166 the impact of different ways of padding the amino acid sequences in a hierarchical Enzyme Commission

167 pe-labeled peptides to validate the proposed amino acid sequences in the database, demonstrating the

168 f variation in specific areas of the protein amino acid sequences in the human population has defined

169 Here, we identify a 28-amino-acid sequence in the TJ adaptor protein ZO-1, whic

170 The present study determined the complete amino acid sequence, in silico 3D structure modeling, an

171 This peptidic natural product exhibited an amino acid sequence including several beta-alanines that

172 ibody sequencing protocols, 100% of antibody amino acid sequences, including identity of Leu and Ile

173 The predicted amino acid sequence indicated SfPER's domain structure a

174 Furthermore, analyses of the allergens' amino acid sequences indicated that they had potential f

175 11 teleost Sws2 photopigments for which both amino acid sequence information and experimentally measu

176 Rigorous validation of amino acid sequence is fundamental in the characterizati

177 rate of synthesis are linked to a protein's amino acid sequence is still not well defined.

178 the intricate relationship among a protein's amino acid sequence, its cotranslational nascent-chain e

179 cles imbued the proapoptotic "KLA" peptides (amino acid sequence: KLAKLAKKLAKLAK) with two key proper

180 Binding of UBA5 to UFM1 is mediated via an amino acid sequence, known as the UFM1-interacting seque

181 How variations in amino acid sequences lead to loss of ancestral activity

182 ehalogenases that are distinguishable at the amino acid sequence level, implying different modes of e

183 m those of commercial vaccine strains at the amino acid sequence level.

184 coded by a wide range of seemingly unrelated amino acid sequences, making it difficult to recognize f

185 These data support the concept that specific amino acid sequence modifications can reduce insulin imm

186 odern methods employ the alignment of DNA or amino acid sequences, mostly not genome-wide but only on

187 ine side chain even in highly repetitive RGG amino acid sequence motifs found in numerous proteins wi

188 atients, there was a cluster of related CDR3 amino acid sequences observed for 18 out of 34 MS patien

189 The amino acid sequence of a protein encodes the blueprint o

190 The amino acid sequence of a protein is the blueprint from w

191 The genetic code, which defines the amino acid sequence of a protein, also contains informat

192 ne, a method that predicts, from the primary amino acid sequence of a protein, which amino acids are

193 dict contacting residue pairs given only the amino acid sequence of a protein.

194 are nucleotide substitutions that alter the amino acid sequence of a protein.

195 The amino acid sequence of AtxA1 is identical to that of Atx

196 The amino acid sequence of DAIP contains 5 potential glutami

197 Our near-infrared tracer is based on the amino acid sequence of exendin-4 and targets the glucago

198 Small variations in the primary amino acid sequence of extracellular matrix proteins can

199 Although some variants do change the amino acid sequence of genes (2.2%), only 3 of the 31 Eo

200 ted how natural interstrain variation in the amino acid sequence of gO influences the biology of HCMV

201 The C-terminal 15-amino acid sequence of K2 is remarkably conserved across

202 In this report, for the first-time, the amino acid sequence of LTPs in lentil has been confirmed

203 The amino acid sequence of mammalian Cx36 harbors a phosphor

204 The amino acid sequence of mouse PAT1 is similar to that of

205 The complete amino acid sequence of nsLTP1 established by intact prot

206 We show that the entire amino acid sequence of R5 interacts with silica during s

207 The amino acid sequence of SpvD is highly conserved across d

208 Thus, the amino acid sequence of the arginine patch can predict th

209 ilable into our analysis and investigate the amino acid sequence of the Bombali virus proteins at the

210 ternal initiation in the mAb adalimumab (the amino acid sequence of the drug Humira) when expressed i

211 ge of which genes are expressed when and the amino acid sequence of the encoded proteins, is direly n

212 identified, for the first time, the minimal amino acid sequence of the full-length Piezo1 that can f

213 ess this issue, we rationally engineered the amino acid sequence of the highly cardiotoxic LC H6 by i

214 yringe delivery, it is also dependent on the amino acid sequence of the multidomain peptide.

215 a particular gate represented by a specific amino acid sequence of the oestrogen receptor (ER).

216 ensemble, which in turn, depend on the exact amino acid sequence of the protein.

217 The amino acid sequence of the RBS naturally varies across a

218 Although the primary amino acid sequence of the RPT domain differs vastly amo

219 position within the TF binding site and the amino acid sequence of the TF.

220 in, stemming from differences in the primary amino acid sequence of the various subclasses, as well a

221 onism is highly species specific because the amino acid sequences of BST-2 are different among animal

222 In fact, the amino acid sequences of BST-2 differ among primate anima

223 The amino acid sequences of farnesyl diphosphate synthase (F

224 The amino acid sequences of four putative B cell epitopes in

225 loyed for HSA and BSA, and variations in the amino acid sequences of HSA and BSA exist; these account

226 mputational studies suggest that the primary amino acid sequences of IDRs encode a variety of their i

227 molecular features that are preserved in the amino acid sequences of orthologous intrinsically disord

228 We thus illustrate how the amino acid sequences of proteins can encode a wide range

229 Evolutionary information contained in the amino acid sequences of proteins specifies the biologica

230 mined the chemical relationships between the amino acid sequences of the complementarity-determining

231 to the FPs of influenza and HIV, the primary amino acid sequences of the FPs of beta-CoVs in 3 differ

232 n this study, we determined the location and amino acid sequences of the FPs of S glycoproteins of 3

233 Minor differences in the amino acid sequences of the opsins are known to lead to

234 orly understood, in part because the primary amino acid sequences of these regions are poorly conserv

235 Analysis of amino acid sequences of three bZIPs does not identify in

236 er, the relationship between the hydrophobic amino acid sequences of transmembrane domains and their

237 The deduced amino acid sequences of UDA have eight out of nine typic

238 cement of cysteine at position 53 of the 191-amino-acid sequence of 22 kDa human GH (hGH) with serine

239 stricted CD8(+) T-cell epitopes from the 693-amino-acid sequence of the VP13/14 protein.

240 Here, we compared the amino-acid sequences of 16 proteins present in the corne

241 We tested the effect of ligand binding and amino acid sequence on the structure and dynamics of the

242 We identified the amino acid sequence on VP4 and its cholangiocyte binding

243 g the probability of generating a given CDR3 amino acid sequence or motif, with or without V/J restri

244 Randomizing the amino-acid sequence or lengthening it had little effect.

245 Changes of amino acid sequences outside the Lys(87)-Leu(122) centra

246 cJHEH) was characterized in terms of deduced amino acid sequence, phylogeny, homology modeling and do

247 role in providing information on the primary amino acid sequence, post-translational modifications, a

248 annotated in the Orange domain, which is an amino acid sequence present in eukaryotic DNA-binding tr

249 utations at up to 53 residues (18%) of their amino acid sequence, primarily distributed across the DN

250 t sequence encoding schemes, including local amino acid sequence profile, secondary structure, solven

251 o-EM structure of DNA-PKcs, allowing precise amino acid sequence registration in regions uninterprete

252 po pathway components and uncovered a unique amino acid sequence required for it.

253 Bioinformatic analysis of the IQGAP1 amino acid sequence revealed potential cleavage sites fo

254 Substance P (SP) [SP + 3H](3+) ion (SP(3+); amino acid sequence RPKPQQFFGLM-NH2).

255 -known levels of protein structure: primary (amino acid sequence), secondary (helices, sheets and tur

256 We identified that Rv1075c amino acid sequence shares similarities with other bacte

257 The amino acid sequence showed 98% similarity and 53% identi

258 t not other IL-1R family members, exhibit an amino acid sequence similar to binding site A of human a

259 g temperatures, which did not correlate with amino acid sequence similarities.

260 ntation was variable and correlated with the amino acid sequence similarity between the homologous ge

261 ependent on structural stability rather than amino acid sequence similarity.

262 rein, two bombolitins displaying significant amino-acid-sequence similarity, BII and BL6, were assess

263 Fixed changes in amino acid sequence, such as A82V in the EBOV glycoprote

264 sion of synaptotagmin-2, which lacks a seven amino acid sequence that contains the phosphorylation si

265 rrently reported protein ligases contain the amino acid sequence that is recognized by that same liga

266 r immune responses, the persistence of viral amino acid sequences that are the major targets of cellu

267 ctions require high affinity for nonspecific amino acid sequences that are ubiquitous in proteins.

268 of this relationship is the total number of amino acid sequences that can fold to a target protein s

269 We thereby identified an 11-amino-acid sequence that is highly conserved in four Luk

270 which allows the facile modification of the amino acid sequence, the introduction of unnatural amino

271 For proteins, variations in the primary amino acid sequence, the secondary structures, and terti

272 timizing the cyclization linker, length, and amino acid sequence, the tightest cyclic peptide achieve

273 ite the lack of detectable similarity in the amino acid sequences, the 2.7 angstrom resolution cryoEM

274 Amino acid sequencing then showed that this effect invol

275 Based on 866 different amino acid sequences this protein is divided into three

276 f dimers are generated by threading a target amino acid sequence through several structural templates

277 ion at the level of both gene expression and amino acid sequence, thus resulting in differences in le

278 an be modified through modest changes in its amino acid sequence to bind and display diverse proteins

279 ol for aligning long diverged nucleotide and amino acid sequences to assembly graphs.

280 In addition to the binding of preferred amino acid sequences to its substrate-binding pocket, ca

281 al amino acids and engineered site-selective amino acid sequences to preserve both activity and struc

282 A protocol for mapping amino-acid sequences to coarse-grained beads enables the

283 Here, we apply deep learning to unlabeled amino-acid sequences to distill the fundamental features

284 Comparison of rodent and human FLAP amino acid sequences together with an analysis of a publ

285 fined by their nucleotide, rather than their amino acid sequence, using targeted editing of the mouse

286 about proteoforms arising from combinatorial amino acid sequence variations and post-translational mo

287 We identified amino acid sequence variations in GRMZM2G075262 that seg

288 stiffness of the PA scaffolds, dependent on amino acid sequence, was found to determine the macrosco

289 ictions for the transmembrane helices to the amino acid sequence we identified a linker of ~20 residu

290 ibrils containing point substitutions in the amino acid sequence, we also show that charged residues

291 RBD to identify new binding modes, and their amino acid sequences were designed to optimize target bi

292 While no clones that shared the same CDR3 amino acid sequences were seen in either HC or MS patien

293 encoded complementarity-determining region 3 amino acid sequence, which could be generated by canonic

294 ake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a b

295 existing tools can not perform alignment of amino acid sequences, which could prove useful in variou

296 DOGL4 shares only limited homology in amino acid sequence with DOG1, a major regulator of seed

297 entire human proteome tiled in contiguous 49 amino acid sequences with 25 amino acid overlaps, enable

298 trains, and this phenomenon was dependent on amino acid sequences within the viral ligand UL18.

299 ation suggest that the subtle differences in amino-acid sequence within the substrate-binding loop re

300 As with modern biology, amino acid sequence would have been a primary determinan