ライフサイエンスコーパス: amino sugar

1 -2,4,6-trideoxy-alpha-d-glycopyranose (UDP-4-amino-sugar).

2 der selection for binding to a model acyclic amino sugar.

3 protected Cerny epoxides and three protected amino sugars.

4 rived acetyl-coenzyme A is used to acetylate amino sugars.

5 le others are related to the biosynthesis of amino sugars.

6 ing natural products such as amino acids and amino sugars.

7 as well as sum total content of neutral and amino sugars.

8 5)N stable isotope probing (SIP) approach to amino sugars.

9 icrobial-derived compounds like proteins and amino sugars.

10 etamido-altrose to their corresponding UDP-4-amino-sugars.

11 range of biologically significant imino and amino sugars [1,4-dideoxy-1,4-imino-D-allitol, 3,6-dideo

12 intermediate that was converted to the novel amino sugar, 1-amino-1-deoxy-2-C-methylerythritol.

13 antified the extracellular gross fluxes of 2 amino sugars, 18 amino acids, and 4 amino acid enantiome

14 out the growth phase of P. furiosus, the UDP amino sugars accumulated (to approximately 14 mM) only d

15 /dermatan sulfates contained only acetylated amino sugar (acetylated galactosamine (GalNAc).

16 based and high-throughput screens against an amino-sugar acetyltransferase enzyme, PglD, involved in

17 leotides, biogenic carboxylic acids, sugars, amino sugars, amino acids and condensing agents.

18 ctams, cyclic urethanes, hydroxy amines, and amino sugars among other important building blocks and i

19 ropeptides were determined by amino acid and amino sugar analysis and matrix-assisted laser desorptio

20 The amino sugar anchors in the major groove of the DNA and p

21 ch to measure soil extracellular metabolite (amino sugar and amino acid) concentrations and fluxes ba

22 reduced levels of several metabolites of the amino sugar and nucleotide sugar metabolic pathways, inc

23 last coupling reaction between the anomeric amino sugar and the oligoamide fragment was carried out

24 ercially unavailable (15)N and (13)C labeled amino sugars and amino acids by hydrolyzing peptidoglyca

25 ets, including microbial necromass biomarker amino sugars and SOC, from two long-term agricultural fi

26 trasaccharidic repeating unit containing two amino sugars and two uronic acids bearing threonine as s

27 carbohydrate-like moieties, (2) peptides or amino sugars, and (3) COO-bonded alkyls.

28 ieties, (2) lignin residues, (3) peptides or amino sugars, and (4) COO-bonded alkyls.

29 uded hexoses, uronic acids, 6-deoxy-hexoses, amino sugars, and alditols.

30 by HPr was important for the utilization of amino sugars, and allosteric inhibition of Adk activity

31 ge of pharmaceutical compounds, amino acids, amino sugars, and natural products.

32 at a number of unusual sugars including many amino sugars are found in these polysaccharides and that

33 These reactive amino sugars are not easily accessible under Maillard re

34 We propose that E. coli recognizes the amino sugars as a harbinger of potential host defence ac

35 C-C-IRMS) for the analysis of (15)N-enriched amino sugars as alditol acetate derivatives prior to app

36 ncorporation of extraneous nitrogen (N) into amino sugars (AS) could reflect the contribution of micr

37 mine synthesis by N-acetylation of the UDP-4-amino-sugar at the C4 position.

38 had an identical structure consisting of an amino sugar backbone of -->6)-alpha-GlcNAc-(1-->4)-beta-

39 alyzes the first step in the biosynthesis of amino sugars by transferring the amino group from l-glut

40 Amino sugars can be used as indices to evaluate the role

41 n trait-associated gene ontology (GO) terms "amino sugar catabolic process", "regulation of fat cell

42 system has been used to demonstrate that an amino sugar characteristic of 14-membered macrolides (D-

43 rdinating the remodeling and recycling of an amino sugar component released from the mycobacterial ce

44 comprehensive analysis of existing biomarker amino sugar data published between 1996 and 2018, combin

45 lso able to ligate 2-oxoglutarate to other 4-amino-sugar derivatives to form UDP-Yelose, UDP-Solosami

46 The amino sugar epimerase N-acetylmannosamine-6-phosphate 2-

47 us, while GalNAc appears to be the preferred amino sugar for the linkage of oligosaccharides to the B

48 robustness of alditol acetate derivatives of amino sugars for the GC-C-IRMS analysis of (15)N-enriche

49 N-acetyl glucosamine (NAG) is a natural amino sugar found in various human tissues with previous

50 ible, component-based synthetic route to the amino sugar fragment of the lincosamide antibiotics is d

51 colytic pathway for utilization of the three amino sugars, GlcNAc, ManNAc, and sialic acid.

52 GLUT2 can transport the amino sugar glucosamine (GlcN), which could increase sub

53 J774 macrophages is rapidly inhibited by the amino sugar glucosamine.

54 Here, we investigated the effect of isomeric amino sugars glucosamine, galactosamine, and their N-ace

55 The amino sugars glucosamine, n-acetyl glucosamine, and gala

56 Methods to analyze neutral and amino sugars have been established for a long time, but

57 is and elongation (FAE), tricarboxylic acid, amino sugar, heme, lipoate, and shikimate metabolism.

58 ontributes to the release of SpA by removing amino sugars [i.e., N-acetylmuramic acid-N-acetylglucosa

59 llowing for the first time quantification of amino sugars in seawater without preconcentration.

60 for the GC-C-IRMS analysis of (15)N-enriched amino sugars in terms of linearity over an enrichment ra

61 GC was achieved using commercially available amino sugars, including glucosamine, mannosamine, galact

62 found for glucosamine, indicating that this amino sugar is released through peptidoglycan and chitin

63 ge of biomolecules such as lipids, proteins, amino sugars, lignins, and tannins in DON from runoff an

64 3 is decorated with less-explored rare deoxy amino sugars like d-quinosamine and d-viosamine, along w

65 ial metabolism and with shifts in DOM toward amino sugars, likely released by cell lysis rather than

66 Pathway analysis revealed the most impact on amino sugar, lysine, sialic acid, hyaluronan and heparan

67 pathways involved in the utilization of this amino-sugar may allow the development of drugs to combat

68 e (GlcNAc), opposite to the pattern of other amino sugar metabolism pathways.

69 a central role in RNA-mediated regulation of amino-sugar metabolism.

70 cal clearing agent, termed UbasM: Urea-Based Amino-Sugar Mixture, that rapidly renders fixed tissue s

71 estion of whether the cells also recycle the amino sugar moieties of cell wall murein has remained un

72 a is auxotrophic for the bacterial cell wall amino sugar N-acetylmuramic acid.

73 Herein we demonstrate that DnmZ is an amino sugar nitrososynthase that initiates the conversio

74 bundance of proteins were mainly involved in amino sugar, nucleotide sugar and fatty acid metabolism,

75 this problem, several nucleic acids based on amino-sugar nucleotides have been studied, and as expect

76 have studied several model systems based on amino-sugar nucleotides.

77 ed in the synthesis and transfer of the free amino sugar of PS A.

78 = O center abstracts the H5'' atom from the amino sugar of the substrate, with subsequent attack of

79 ation pathways for 15 hexoses, pentoses, and amino sugars of biological origin have been assessed.

80 The amino sugars of the murein are also efficiently recycled

81 sal of a minimal monooxygenase mechanism for amino sugar oxidation by ORF36.

82 Indeed, deoxy and amino sugars play important roles in the virulence of gr

83 reover, uptake analysis and profiling of the amino sugar pool revealed that NagA inactivation blocks

84 on the fate and levels of the intracellular amino sugar pool.

85 cella species due to the absence of the rare amino sugar quinovosamine in the three other species.

86 dase and that it is essential for PG-derived amino sugar recycling via an unusual pathway.

87 ing a ring cleavage remnant of the innermost amino sugar residue of an N-glycan can be relied upon to

88 ha-(1-->1)-linked to the reducing (proximal) amino sugar residue.

89 dition of aminoarabinose [positively charged amino sugar residue], and retention of 3-hydroxydecanoat

90 ycan precursor was (13)C-labeled on all four amino sugar residues and enzymatically derivatized to pr

91 n 1 order of magnitude slower than those for amino-sugar ribonucleotides under the same conditions, a

92 aled that it is composed of an unusual three amino-sugar sequence repeat of [-3)XylNAc4OAc(alpha1-3)G

93 Glucosamine (GlcN) is an amino sugar sold over-the-counter and is widely used as

94 iles are also consistent with the GDP-linked amino sugar substrate entering the active site in its un

95 In addition, amino sugars such as glucosamine, which do not ionize in

96 cids, fatty acids, amines, alcohols, sugars, amino-sugars, sugar alcohols, sugar acids, organic phosp

97 phosphorylase is a major regulatory point in amino sugar synthesis in encysting Giardia and that its

98 stry to forge strategic bonds within complex amino sugar targets and employs a glycal epoxide as a ve

99 The PS A of 9343 contains an unusual free amino sugar that is essential for abscess formation by t

100 (Neu5Ac) is a negatively charged nine-carbon amino sugar that is often the peripheral sugar in human

101 tained by studying mutants unable to recycle amino sugars, the pathway for recycling is revealed.

102 This amino sugar then undergoes a NAD dependent oxidative dea

103 s involved in the four-electron oxidation of amino sugars to nitroso sugars.

104 he acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N'-diacetylbacillosamine, util

105 , 4, 6-trideoxy-alpha-D-glucopyranose (UDP-4-amino-sugar) to form UDP-BacAc(2).

106 he pathway variations were attributed to the amino sugar transport, phosphorylation, and deacetylatio

107 Streptomyces fradiae to utilise a different amino sugar, tylM2 was integrated into S. erythraea SGT2

108 They were identified as two uridylated amino sugars, UDP N-acetylglucosamine and UDP N-acetylga

109 [R]-gamma-Py-Ind) were coupled with selected amino sugars using DIEA in DMF.

110 We found that the UDP-4-amino-sugar was readily synthesized from UDP-GlcNAc in a

111 Detection limits for amino sugars were between 1 and 4 nM (signal-to-noise ra

112 Amino sugars were determined in natural samples, includi

113 Furthermore, the amino sugars were found to form fructosazine, react with

114 of citrate, acetyl coenzyme A, or the UDP-4-amino-sugar were solved.

115 entral role in the biosynthesis of deoxy and amino sugars, which are involved in a variety of biologi