ライフサイエンスコーパス: amino-terminal

1 tibodies map to major linear epitopes in the amino terminal 1 to 14 residues of AB, the antibodies di

2 They all share an amino-terminal 11-mer repeat (11mr) amphipathic region s

3 chimeric gene coding for the soybean native amino-terminal 86 amino acids fused to an insensitive sh

4 The amino-terminal 91-amino-acid domain of human MX2 confers

5 eric MX1/2 proteins, we demonstrate that the amino-terminal 91-amino-acid domain of MX2 confers full

6 nanometer diameter ovoid structures with 2-3 amino-terminal Abeta antibody binding sites, distinct fr

7 NatE complex can be a major contributor for amino-terminal acetylation at the ribosome exit tunnel.

8 Amino-terminal acetylation is a critical co-translationa

9 Amino-terminal acetylation is among the most ubiquitous

10 eins in a eukaryotic cell carried out by six amino-terminal acetyltransferases (NATs).

11 ubstrate accessibility of PhCCD1 through the amino-terminal addition of membrane destination peptides

12 e large, 140-250-kilodalton enzymes, with an amino-terminal alpha-helical region and a carboxy-termin

13 branes, which is mediated exclusively by the amino-terminal ALPS motif.

14 acetyl group to the alpha-amino group of the amino-terminal amino acid of proteins, which causes the

15 In vitro, dACE2, which lacks 356 amino-terminal amino acids, was non-functional in bindin

16 r data support a stepwise model in which the amino-terminal amphipathic helix of GTP-bound Sar1 stabl

17 lectron microscopy analyses to show that the amino-terminal amphipathic helix of SecA and the ribosom

18 that lies within the combined properties of amino terminal and transactivation domains.

19 e determined sites of phosphorylation in the amino-terminal and carboxy-terminal domains that are pos

20 ) is flanked in all FGFs by highly divergent amino-terminal and carboxy-terminal sequences of variabl

21 X-ray crystal structures for the soluble amino-terminal and ligand-binding domains of glutamate r

22 nstrating extensive interactions between the amino-terminal and ligand-binding domains.

23 s large conformational rearrangements of the amino-terminal and ligand-binding domains.

24 The 5'-exon is held between the Prp8 amino-terminal and linker domains, and base-pairs with U

25 res of actin complexes with the unstructured amino-terminal and the leucine-rich repeat carboxy-termi

26 t nonglycosylated XXT2 lacking its cytosolic amino-terminal and transmembrane domain displays high ca

27 actions among cytoplasmic domains, including amino-terminal ankyrin repeats.

28 The amino-terminal aptamers probe were then attached to the

29 e-like N() with a disordered solvent-exposed amino-terminal beta-strand.

30 ve small-molecule inhibitors that target the amino-terminal bromodomains of BRD4, have been shown to

31 t transgenic mice to explore the role of the amino-terminal (BubR1(N)) and internal (BubR1(I)) Cdc20-

32 Forty amino-terminal C protein residues are dispensable for th

33 We previously identified the amino-terminal C2 domain of PKCtheta as a phosphotyrosin

34 he 'small' and 'large' SRs contain a compact amino-terminal catalytic domain, but differ conspicuousl

35 Bub3 promotes binding of BubR1's conserved, amino terminal Cdc20 binding domain to a site in Cdc20 t

36 of FGF2, whereas IGF1 displayed homogeneous amino-terminal cleavage with complete removal of the bom

37 otiomyceta, has an unusual structure with an amino-terminal coiled-coil and a carboxy-terminal zinc b

38 her analysis of conserved amino acids in the amino-terminal conserved domain revealed that the tyrosi

39 We demonstrated that the amino-terminal conserved domain was essential for Arabid

40 We have investigated the influence of the amino terminal copper and nickel binding (ATCUN) motif o

41 We report here the amino terminal crystal structures of wild-type FMRP, and

42 protein interactions can occur through their amino-terminal CTS region.

43 ), as a low oxygen affinity (high-K (m)O(2)) amino-terminal cysteine dioxygenase that transduces the

44 pha-amino and sulfhydryl substituents of its amino-terminal cysteine residue.

45 ADO catalyzes the conversion of amino-terminal cysteine to cysteine sulfinic acid and is

46 nteraction between ORF31 and ORF24, (ii) the amino-terminal cysteine-rich and carboxyl-terminal basic

47 ion of cysteine residues clustered within an amino-terminal cytoplasmic domain.

48 of Burkitt's lymphomas, aggregate within an amino-terminal degron important for proteasomal destruct

49 We identified two HSV-1 ICP27 amino-terminal deletion mutants with a similar release d

50 Amino-terminal deletions of PGD2 fusions with a free C t

51 The amino terminal dendrimers were analyzed by diffusion-ord

52 e present an easy and efficient synthesis of amino terminal dendrons, combining protection/deprotecti

53 ide bond formation A (DsbA) proteins and the amino-terminal dimerization domain of macrophage infecti

54 ICP55 is unusual, as it involves breaking an amino-terminal diserine that is not known as an ICP55 su

55 chemoreceptor channel TRPA1 via formation of amino-terminal disulphide bonds, which results in sustai

56 cocrystallization of this molecule with the amino terminal domain (ATD) of the hmGlu2 receptor prote

57 g through the entire molecule composed of an amino terminal domain (ATD), a ligand-binding domain (LB

58 nding site in the GluN1-GluN2B NMDA receptor amino terminal domain and show that the interaction of t

59 s of activity that reside between the GluN2C amino terminal domain and the GluN2C agonist binding dom

60 udies have added S1PR2 as a receptor for the amino terminal domain of Nogo-A, and have demonstrated s

61 how allosteric inhibitors, acting within the amino terminal domain, further stabilize the LBD layer.

62 KSHV-infected cells, which binds through its amino terminal domain.

63 n constructs have revealed the importance of amino-terminal domain (46-290) for memory suppression wh

64 receptor (AR) is recruited by ELK1, via its amino-terminal domain (A/B), as a transcriptional co-act

65 The amino-terminal domain (ATD) of AMPA receptors (AMPARs) a

66 olutionarily distinct structural domains: an amino-terminal domain (ATD), a ligand-binding domain (LB

67 t binds to an extracellular domain called an amino-terminal domain (ATD).

68 ain (LBD) and structural rearrangement of an amino-terminal domain (ATD).

69 , PrP(Sc) We examined the role of the PrP(c) amino-terminal domain (N-terminal domain [NTD], amino ac

70 r with each protomer containing an L30e-like amino-terminal domain (NTD) and a SPOUT methyltransferas

71 re clearly define the roles of the HTLV-1 CA amino-terminal domain (NTD) and CA CTD in particle bioge

72 a methionine residue at the junction of the amino-terminal domain (NTD) and the carboxy-terminal dom

73 HIV-1 capsid protein contains an amino-terminal domain (NTD) comprising seven alpha-helic

74 Furthermore, the GluN1 amino-terminal domain adopts a more open conformation wh

75 , uncharged linker between the lethal factor amino-terminal domain and diphtheria toxin A chain exped

76 e processing of N-glycosylation sites in the amino-terminal domain and downstream linker region.

77 ermine, an allosteric potentiator, opens the amino-terminal domain cleft of both the GluN2B subunit a

78 and binding of allosteric modulators to the amino-terminal domain determine the open probability of

79 We show how Cbln1 hexamers "anchor" GluD2 amino-terminal domain dimers to monomeric beta-NRX1.

80 rmore, the Arabidopsis HDR contains an extra amino-terminal domain following the transit peptide that

81 spectroscopy that the Escherichia coli NusG amino-terminal domain forms a complex with the acidic re

82 d and twisted fashion through interdigitated amino-terminal domain interactions, form a kinked centra

83 anine-rich kinase (SPAK) binding site in the amino-terminal domain is conserved.

84 One protein that binds Rb1 through the amino-terminal domain is encoded by Thoc1, a required co

85 The FliG amino-terminal domain is organized in a regular array wi

86 binds to m(6)A-containing mRNA, whereas the amino-terminal domain is responsible for the localizatio

87 The unusually long amino-terminal domain of 550 residues that precedes the

88 edicted to code for a protein containing the amino-terminal domain of DNAJB1, a homolog of the molecu

89 ne-distal immunoglobulin-variable (IgV)-like amino-terminal domain of each is crucial to these intera

90 The amino-terminal domain of ExsA (NTD) is thought to mediat

91 different ORF34 domains interacted with the amino-terminal domain of HIF-1alpha.

92 Second, the NS5 RdRP domain also binds the amino-terminal domain of hSTAT2.

93 Additionally, we demonstrate that the amino-terminal domain of human and bank vole PrP(c)s req

94 o may recognize the helical structure of the amino-terminal domain of Izumo1.

95 3Kgamma revealed that only the noncatalytic, amino-terminal domain of p110gamma was necessary and suf

96 We find that an amino-terminal domain of PCM1 can restore ciliogenesis a

97 Snu114 and the amino-terminal domain of Prp8 position U5 snRNA to inser

98 ate by hydrogen bonding to a tyrosine in the amino-terminal domain of Prp8.

99 wn assays and showed that hsp70 binds to the amino-terminal domain of SOD2.

100 in CHO cells, we show that the cleft of the amino-terminal domain of the GluN2B subunit, which has a

101 The HIV-1 matrix (MA) protein is the amino-terminal domain of the HIV-1 precursor Gag (Pr55Ga

102 We demonstrate that the amino-terminal domain of the normal prion protein, PrP(c

103 tive activity mediated by the ligand-mimetic amino-terminal domain of the receptor.

104 its located two regions in the extracellular amino-terminal domain of the subunit: the E loop (a loop

105 a more extensive set of interactions in the amino-terminal domain plays some role in the actions of

106 nteraction and cell-to-cell movement and the amino-terminal domain required for importin-alpha intera

107 tization is accompanied by disruption of the amino-terminal domain tetramer in AMPA, but not kainate,

108 DNA binding protein that binds via its small amino-terminal domain to high affinity arm-type DNA site

109 In a proposed model for AMPAR assembly, the amino-terminal domain underlies the formation of a dimer

110 In this study, the HTLV-1 capsid amino-terminal domain was found to provide distinct cont

111 The amino-terminal domain with a fold distinct among known T

112 These data suggest that interactions of the amino-terminal domain with the rest of the PrP(c) molecu

113 These domains, together with the amino-terminal domain, constitute a network of superheli

114 chinery depends on the integrity of both the amino-terminal domain, containing a number of putative R

115 of the MCM complex specifically bound to the amino-terminal domain, while MCM6 bound to both the amin

116 nded domain and papain-like proteases by its amino-terminal domain.

117 y bioinformatics and mutagenesis in the TGB1 amino-terminal domain.

118 be an essential triple-arginine motif in the amino-terminal domain.

119 mainly contributed by the residues from the amino-terminal domain.

120 es (Ser(44), Ser(46), and Ser(48)) within an amino-terminal domain.

121 racellular interactions through the receptor amino-terminal domain.

122 resolve the crystal structure of ACF7's NT (amino-terminal) domain, which mediates F-actin interacti

123 the interface of the ligand binding and the amino terminal domains in a homology model of GluN1/GluN

124 Cocrystallization of 14a with the amino terminal domains of hmGlu2 and hmGlu3 combined wit

125 employing recombinant human mGlu2/3 receptor amino terminal domains, molecular modeling, and site-dir

126 In the absence of Ro, the GluN2A and GluN2B amino-terminal domains (ATDs) adopt "closed" and "open"

127 itive homo- and hetero-dimerization of their amino-terminal domains (ATDs) is a key step controlling

128 architectural diversity involving additional amino-terminal domains (NTDs).

129 and 349-402 for synaptic suppression, while amino-terminal domains including NLS1 are dispensable.

130 r the suppression of axonal branching, while amino-terminal domains including NLS1 are dispensable.

131 elical bundle, directly interacting with the amino-terminal domains of adjacent subunits.

132 udied high-affinity interactions between the amino-terminal domains of GluA2 and GluA3 AMPA receptors

133 ts in proteasome-mediated degradation of the amino-terminal domains of NLRP1B, liberating a carboxyl-

134 rovided a platform for further dissection of amino-terminal domains of nsp3.

135 C1ql2 and C1ql3 specifically bound the amino-terminal domains of postsynaptic GluK2 and GluK4 K

136 ere the actions of two proteases release the amino-terminal domains of SREBPs that travel to the nucl

137 -RAG2 heterotetramer is 'Y-shaped', with the amino-terminal domains of the two RAG1 chains forming an

138 dence that the inherent conformations of the amino-terminal domains vary based on the subunit and mat

139 of isolated water-soluble ligand-binding and amino-terminal domains, as well as solving the first cry

140 COP9 signalosome, eIF3) or MPN (Mpr1, Pad1, amino-terminal) domains constitute the structural core o

141 Interestingly, deleting the amino-terminal EF-hands activates proteolysis prematurel

142 We previously reported the amino-terminal eight residues of the HIV-1-fusion peptid

143 ned in frame with a CPD (YARKARRQARR) at the amino-terminal end and hexahistidine at the carboxy-term

144 in the carboxyl-terminal end of ECL2 and the amino-terminal end of ECL3, and Cys(10)-sec not efficien

145 d by abnormal polyglutamine expansion in the amino-terminal end of the huntingtin protein (Htt) and c

146 h ligands, the crystal structure of the Flfl amino-terminal EVH1 domain bound to a CENP-C peptide rev

147 Activation of PKR required the amino-terminal EVH1 domain of Dcp1a.

148 was found for 8 mutations distributed among amino terminal, exonuclease and catalytic domains.

149 foamy virus (PFV) consists of four domains: amino terminal extension (NED), amino terminus (NTD), ca

150 One paralog of each protein contains an amino-terminal extension that targets proteins to mitoch

151 phorylation sites to the otherwise divergent amino-terminal extensions on these pollen sPPases.

152 ructural studies have been restricted to the amino-terminal extracellular domain, providing little un

153 peptide hormones, has been restricted to the amino-terminal extracellular domain, thus providing litt

154 depends on interactions taking place at the amino-terminal (FERM) and carboxyl-terminal (FAT) domain

155 es of the same NS1 monomer, consisting of an amino-terminal foot, a head and body domains connected t

156 receptor protomers, extracellular domain and amino terminal fragment (NTF), and the 7TM or C-terminal

157 Further, when an amino-terminal fragment (Met(1)-Arg(33)) of the N170K/K2

158 tify a prostate apoptosis response-4 (Par-4) amino-terminal fragment (PAF) that is released by divers

159 The amino-terminal fragment of Ara h 1, a member of a family

160 y of the BPP fraction was due to the 5-7 kDa amino-terminal fragment of Ara h 1.

161 se-11 cleaves gasdermin D, and the resulting amino-terminal fragment promotes both pyroptosis and NLR

162 Ligation of uPAR with the amino-terminal fragment recruited alpha5beta1 integrin a

163 with the urokinase receptor binding domain (amino-terminal fragment) leads to enhanced migration of

164 Within the amino-terminal fragment, a functional J domain is necess

165 e gasdermin proteins to produce pore-forming amino-terminal fragments causes inflammatory cell death

166 g simulations, evidenced that both chain and amino terminal function characterized by higher hydrophi

167 previously characterized viruses expressing amino-terminal fusions, this virus expresses more VP26 f

168 ry similar domain architecture, including an amino terminal GTPase domain and two extended helical bu

169 40-60 amino acid residues each, spanning the amino-terminal half of Erb1.

170 of CI (cylindrical inclusion) and P3N-PIPO (amino-terminal half of P3 fused to Pretty Interesting Po

171 ving two helicase modules, of which only the amino-terminal helicase domain appears to be catalytical

172 hat a mutant form of human Dicer lacking the amino-terminal helicase domain can process double-strand

173 and the negatively charged EDGE motif on the amino terminal helix of G(i3).

174 An amino-terminal helix from each of two subunits of the ca

175 An amino-terminal helix location underpins the covalent lin

176 In contrast, removal of the amino-terminal hydrophilic SPX domain does not affect th

177 a conserved PtdSer binding pocket within the amino-terminal IgV domain.

178 HopQ binds the amino-terminal IgV-like domain of human CEACAM1, CEACAM3

179 PECAM-1 homophilic interactions, mediated by amino-terminal immunoglobulin homology domain 1, contrib

180 ophilic-binding domain, which is composed of amino-terminal immunoglobulin homology domains 1 and 2 (

181 interactions, known to be mediated by its 2 amino-terminal immunoglobulin homology domains, are esse

182 Moreover, data on carboxyl- and amino-terminal interactions were not provided, as the am

183 ignature of three amino acids located at the amino-terminal intracellular region.

184 BA-KEN-ABBA motifs, and association with the amino-terminal KEN box required to form the MCC.

185 al Akt/NO synthase activation, reduced c-Jun amino terminal kinase phosphorylation, and decreased oxi

186 We further show that c-Jun amino-terminal kinase (JNK) plays a pivotal role in medi

187 The c-Jun amino-terminal kinase (JNK) plays a role in inflammation

188 Here we demonstrate that c-Jun amino-terminal kinase (JNK) signaling is crucial for ger

189 l-regulated kinase 1/2 (ERK1/2), p38 and Jun amino-terminal kinase (JNK), which consequently potentia

190 ular signal-regulated kinase, p38, and c-Jun amino-terminal kinase mitogen-activated protein kinase (

191 Amino-terminal LANA attaches to chromosomes by binding h

192 A construct lacking the amino-terminal leader and transmembrane domain caused cy

193 The amino-terminal ligand binding domain of SIRPalpha is hig

194 An amino-terminal linker within FAK is essential for its bi

195 n human LAMB2 cluster in or near the laminin amino-terminal (LN) domain, a domain required for extrac

196 By contrast, interaction with the amino-terminal longin domain conferred specificity on VA

197 Hexamethylene amiloride binds the polar amino-terminal lumen, whereas acidic pH affects the carb

198 plicating distal effects of the carboxyl- on amino-terminal membrane binding.

199 ophobic amino acids, which projects from the amino-terminal membrane-binding domain.

200 of both FGF2 and IGF1, suggesting that FGF2 amino-terminal microheterogeneity does not alter mitogen

201 proteins as truncated forms showed that the amino-terminal modular low-density lipoprotein receptor

202 p.R3S substitution occurs within a conserved amino-terminal motif (RRKQxxP) of BCL11B and reduces int

203 murine TRPC6 FRET constructs with homologous amino-terminal mutations (M131T, G108S) that had been id

204 This binding also triggers exposure of an amino-terminal myristate moiety, which anchors Gag to th

205 In the circulation, alpha2AP undergoes both amino terminal (N-terminal) and carboxyl terminal (C-ter

206 uding the highly conserved membrane-proximal amino-terminal (N-terminal) region, is distinct from oth

207 ecies, directly interacts with the cytosolic amino terminal (NT) domain of the yeast Golgi V-ATPase a

208 In Arabidopsis thaliana Gln-specific amino-terminal (Nt)-amidase (NTAQ1) controls the express

209 e Factor transcription factors (ERFVIIs) via amino-terminal (Nt-) cysteine [1, 2].

210 The amino-terminal nucleotide binding domain rotates to clos

211 phenotypes, whereas missense variants within amino terminal or ligand-binding domains (misATD+LBD) an

212 ntaining point mutations or deletions in the amino-terminal or the carboxy-terminal regions of the E

213 We show here that amino-terminal p53 (ATp53) mutations often result in the

214 as well as a chimeric protein containing the amino-terminal part of AtCGL160 and Synechocystis sp. PC

215 CTX)) and bone formation (procollagen type I amino-terminal peptide (PINP)) were estimated using Cox

216 Monitoring of amino-terminal peptides showed that Arabidopsis ICP55 wa

217 ase domain from the inhibitory action of the amino-terminal photosensory portion of the photoreceptor

218 tiana tabacum) pollen tubes, SEC3a displayed amino-terminal Pleckstrin homology-like domain (SEC3a-N)

219 t huntingtin protein (mHTT) with an expanded amino-terminal polyglutamine (poly(Q)) stretch.

220 in, we present the solution structure of the amino-terminal portion of mouse HOP2, which contains a t

221 We propose that the amino-terminal portion of p33 is unstructured when VacA

222 xf2/Panx complex formation and show that the amino-terminal portion of Panx is sufficient to induce t

223 ustered missense mutations were found at the amino-terminal portion of the delta subunit of guanine n

224 Using 5 synthetic peptides that spanned the amino-terminal portion of the hMPV N protein, we identif

225 ing FrmR(E64H) reveals that an FrmR-specific amino-terminal Pro(2) is proximal to Cys(35), and these

226 and outcomes are worse; however, the role of amino-terminal pro-B-type natriuretic peptide (NT-proBNP

227 -directed medical therapy (GDMT) by reducing amino-terminal pro-B-type natriuretic peptide (NT-proBNP

228 To determine whether an amino-terminal pro-B-type natriuretic peptide (NT-proBNP

229 Combined measurement of soluble ST2 and amino-terminal pro-B-type natriuretic peptide at 12 hour

230 e combination of results for soluble ST2 and amino-terminal pro-B-type natriuretic peptide provides e

231 The combination of soluble ST2 and amino-terminal pro-B-type natriuretic peptide showed exc

232 lue of serial measurement of soluble ST2 and amino-terminal pro-B-type natriuretic peptide to clinica

233 ers elevated (soluble ST2, >/= 500 ng/mL and amino-terminal pro-B-type natriuretic peptide, >/= 4,500

234 pe NP (BNP) level of 250 pg/mL or less or an amino-terminal pro-brain-type NP (NT-proBNP) decrease of

235 Advanced cardiac stage III patients (amino-terminal pro-natriuretic peptide type B >8500 ng/L

236 hemoconcentration, weight loss, reduction in amino terminal, pro B-type natriuretic peptide, increase

237 t of high-sensitivity C-reactive protein and amino-terminal probrain natriuretic peptide is debated.

238 , apolipoprotein B/apolipoprotein A-1 ratio, amino-terminal probrain natriuretic peptide, high-sensit

239 ssense point mutation in the procollagen III amino terminal propeptide segment (PIIINP) of collagen,

240 Decreased levels of serum procollagen type 1 amino-terminal propeptide and tartrate-resistant acid ph

241 the first exercise bout for determination of amino-terminal propeptide of collagen I content.

242 elatin 1 h before exercise showed double the amino-terminal propeptide of collagen I in their blood,

243 mains, but genetic evidence suggests that an amino-terminal protein interaction domain is also import

244 JAK2 induced the phosphoactivation of c-Jun amino-terminal protein kinase (JNK) and the downstream t

245 Upon dsDNA engagement, the AIM2 amino-terminal pyrin domain (PYD) is responsible for dow

246 as proSAAS (named after four residues in the amino terminal region) has many attractive properties.

247 le metabolites (most likely depending on the amino-terminal region around the highly conserved cystei

248 Moreover, its amino-terminal region binds FLASH, an RDH-specific 3'-en

249 The amino-terminal region forms a tight dimerization domain

250 The MDM2 amino-terminal region is sufficient to bind NDUFS1, alte

251 These results indicate that the amino-terminal region of HDAg is in close contact with t

252 ere pS denotes phosphoserine) located in the amino-terminal region of HopQ1.

253 etiological missense variants cluster in the amino-terminal region of human BCL11A, and we demonstrat

254 We show that the amino-terminal region of JAZ10.4 contains a cryptic MYC2

255 An amino-terminal region of LifA shares homology with the c

256 We determined that the amino-terminal region of SidE was essential for SidJ-med

257 tion that links the activity of SidJ and the amino-terminal region of SidE, which is required to modu

258 otal of six SN-HPCs for mutations within the amino-terminal region of the gene CTNNB1 (cadherin-assoc

259 er caused by polyglutamine expansions in the amino-terminal region of the huntingtin (Htt) protein.

260 hat MLO homooligomerization, mediated by the amino-terminal region of the protein, and carboxyl-termi

261 mutation affecting structural aspects of the amino-terminal region of the protein, and support the co

262 - map, density corresponding to the immature amino-terminal region of VI indicates that in the absenc

263 etic studies show critical roles for both an amino-terminal region of Zta and the basic DNA binding d

264 Wnt inhibitors that act by cleaving the Wnt amino-terminal region to inactivate specific Wnt ligands

265 roach showed that replacement of the pre-TM1 amino-terminal region with the corresponding P2X2 recept

266 irectly with the plasma membrane through its amino-terminal region.

267 s observed for HLA peptides derived from the amino terminal regions of the proteins, suggesting that

268 minal interactions were not provided, as the amino-terminal regions of murine and human TRPC6 were no

269 Amino-terminal regions of secretin-family peptides conta

270 on whereas carboxyl domain (598-854) and the amino-terminal residues (1-45) including the nuclear loc

271 We found that the extreme amino-terminal residues of the chemokine XCL1 (Val(1), G

272 ncated form, termed tAlv-a1-pHCl, lacking 37 amino-terminal residues that precede the N-terminal heli

273 ExoS is bifunctional, with an amino-terminal RhoGAP and a carboxy-terminal ADP-ribosyl

274 in-ligases, characterized by the presence of amino-terminal RING (really interesting new gene) and PH

275 The protein contains one amino-terminal RNA recognition motif (RRM) known to bind

276 membrane localization of PBS1 is mediated by amino-terminal S-acylation.

277 ins are synthesized as precursors containing amino-terminal Sec signal peptides and are exported thro

278 H1 gene encodes a two-domain protein with an amino-terminal Sec14-like phosphatidylinositol transfer

279 s a conformational change, incorporating the amino-terminal segment of the RCL into serpin beta-sheet

280 This required the amino-terminal sequence of CAII, a region that binds oth

281 iates translation from codon 1, possesses an amino-terminal signal sequence, and is a type one integr

282 mitochondrial proteins are synthesized with amino-terminal signal sequences.

283 und that Ptenl(-/-) mice, which lack the NH2-amino terminal splice variant of PTEN, were unable to er

284 findings demonstrate that the occurrence of amino-terminal structural homogeneity may be associated

285 Our new data demonstrate that the very amino-terminal subdomain of Venezuelan equine encephalit

286 The sensitivity to amino-terminal substitution was specific for DAT, becaus

287 l sequence, outer membrane localization, and amino-terminal surface exposure.

288 ate that CENP-B directly binds both CENP-A's amino-terminal tail and CENP-C, a key nucleator of kinet

289 anslational addition of methyl groups to the amino terminal tails of histone proteins regulates cellu

290 Histone amino-terminal tails (N-tails) are required for cellular

291 We show that the amino-terminal tails of the catalytic subunit of Pol alp

292 s characterized into 3 distinct domains: the amino terminal, the tandem repeat, and the carboxyl term

293 while DNA intimately contacts the downstream amino-terminal tier of the MCM motor ring.

294 ctional inactivation, their relevance in the amino-terminal transactivation domain is unclear.

295 RDs (UT-69, UT-155, and (R)-UT-155) bind the amino-terminal transcriptional activation domain AF-1, w

296 duced response, GIRK phosphorylation at this amino terminal tyrosine residue (Y12) enhances channel d

297 like lectins that recognize sialoglycans via amino-terminal V-set domains.

298 of this new study demonstrate that the very amino-terminal VEEV capsid-specific subdomain SD1 is a c

299 l-terminal yellow fluorescent protein-SlGGB1/amino-terminal yellow fluorescent protein-Gbeta heterodi

300 The amino-terminal zinc (N) finger of GATA1 critically contr