ライフサイエンスコーパス: amino-terminal domain

1 KSHV-infected cells, which binds through its amino terminal domain.

2 f a conserved triple serine motif within the amino-terminal domain.

3 nd stability of the intrinsically disordered amino-terminal domain.

4 e open reading frame (ORF) within the common amino-terminal domain.

5 fs, referred to as LR1 and LR2, in the EBNA1 amino-terminal domain.

6 responsible for substrate specificity in the amino-terminal domain.

7 Down-regulation of TBK1 requires the amino-terminal domain.

8 diated crosslinking of annexin-1 through its amino-terminal domain.

9 glutathione to the APS reduction site on the amino-terminal domain.

10 de and one within the variable region of the amino-terminal domain.

11 f a basic amino acid (HKH) motif on the Cx40 amino-terminal domain.

12 uman GLI2 mutants, now containing the entire amino-terminal domain.

13 n the positively charged residues within the amino-terminal domain.

14 ins 6 and 7 functionally cooperated with the amino-terminal domain.

15 nded domain and papain-like proteases by its amino-terminal domain.

16 es (Ser(44), Ser(46), and Ser(48)) within an amino-terminal domain.

17 y bioinformatics and mutagenesis in the TGB1 amino-terminal domain.

18 be an essential triple-arginine motif in the amino-terminal domain.

19 racellular interactions through the receptor amino-terminal domain.

20 mainly contributed by the residues from the amino-terminal domain.

21 t the interface between the GluN1 and GluN2B amino-terminal domains.

22 may stem from differential regulation by the amino-terminal domains.

23 n-heparin-binding regions of the fibronectin amino-terminal domains.

24 panning domain to productively interact with amino-terminal domains.

25 separation of the two dimeric extracellular amino-terminal domains.

26 specific core-type binding sites whereas the amino-terminal domain (1-70) is responsible for cooperat

27 n constructs have revealed the importance of amino-terminal domain (46-290) for memory suppression wh

28 receptor (AR) is recruited by ELK1, via its amino-terminal domain (A/B), as a transcriptional co-act

29 beta barrel into and the translocation of an amino-terminal domain across the outer membrane.

30 Furthermore, the GluN1 amino-terminal domain adopts a more open conformation wh

31 a negative charge substitution (N2E) in the amino terminal domain allow unequivocal separation of th

32 recombinant fragments encoding the utrophin amino-terminal domain alone or in combination with vario

33 ull-length utrophin more faithfully than the amino-terminal domain alone.

34 ing cross-over between the twofold symmetric amino terminal domain and a twofold symmetric ligand bin

35 From fits of the amino terminal domain and LBD domains into the density m

36 nding site in the GluN1-GluN2B NMDA receptor amino terminal domain and show that the interaction of t

37 s of activity that reside between the GluN2C amino terminal domain and the GluN2C agonist binding dom

38 ccurs between the extracellular zinc-binding amino terminal domain and the glutamate-binding domain o

39 dicted from the primary sequence of P3H1: an amino-terminal domain and a carboxyl-terminal domain cor

40 In utrophin, the amino-terminal domain and an adjacent string of the firs

41 , uncharged linker between the lethal factor amino-terminal domain and diphtheria toxin A chain exped

42 e processing of N-glycosylation sites in the amino-terminal domain and downstream linker region.

43 e report the crystal structure of the capsid amino-terminal domain and examine the self-association p

44 Our data indicate that the amino-terminal domain and first 10 consecutive spectrin-

45 ecular interaction mediated by Arg-61 in the amino-terminal domain and Glu-255 in the carboxyl-termin

46 omains were found to face the cytoplasm (the amino-terminal domain and loops B and D), and the other

47 monomeric nucleocapsid (N) proteins with its amino-terminal domain and positions them for assembly in

48 sponses through disruption or removal of the amino-terminal domain and relief of Zn(2+) inhibition.

49 Cdc14A binds to Wee1 at its amino-terminal domain and reverses CDK-mediated Wee1 pho

50 is an enhanced binding affinity between the amino-terminal domain and the CaM-binding sequence of th

51 tion of new contact interactions between the amino-terminal domain and the CaM-binding sequence that

52 rine protease motif (GDSGSP) in the secreted amino-terminal domain, and the predicted peptide shows m

53 o acid (HKH) motif at positions 15-17 on the amino terminal domain are essential for this inhibitory

54 r identified the juxtamembrane region of its amino-terminal domain as the region of covalent attachme

55 of isolated water-soluble ligand-binding and amino-terminal domains, as well as solving the first cry

56 The amino terminal domain (ATD) of ionotropic glutamate rece

57 cocrystallization of this molecule with the amino terminal domain (ATD) of the hmGlu2 receptor prote

58 g through the entire molecule composed of an amino terminal domain (ATD), a ligand-binding domain (LB

59 omain (LBD) and more recently for the larger amino terminal domain (ATD).

60 ssembly involve an initial step in which the amino terminal domains (ATD) assemble as dimers.

61 uN2A-GluN2D chimeric subunits implicates the amino-terminal domain (ATD) as a strong determinant of a

62 of modulator compounds to the extracellular amino-terminal domain (ATD) distinct from the L-glutamat

63 gulated by binding of small compounds to the amino-terminal domain (ATD) in a subtype-specific manner

64 The amino-terminal domain (ATD) of AMPA receptors (AMPARs) a

65 Here, we report that the extracellular amino-terminal domain (ATD) of the NR2 subunit controls

66 The amino-terminal domain (ATD) of yeast mitochondrial RNA p

67 olutionarily distinct structural domains: an amino-terminal domain (ATD), a ligand-binding domain (LB

68 molecules, such as zinc, which bind to their amino-terminal domain (ATD).

69 mmon architecture, including the 400-residue amino-terminal domain (ATD).

70 molecular process principally encoded by the amino-terminal domain (ATD).

71 t binds to an extracellular domain called an amino-terminal domain (ATD).

72 ain (LBD) and structural rearrangement of an amino-terminal domain (ATD).

73 In the absence of Ro, the GluN2A and GluN2B amino-terminal domains (ATDs) adopt "closed" and "open"

74 itive homo- and hetero-dimerization of their amino-terminal domains (ATDs) is a key step controlling

75 The extracellular amino-terminal domains (ATDs) of the ionotropic glutamat

76 subtypes is regulated by their extracellular amino-terminal domains (ATDs).

77 were explored using a homology model of the amino-terminal domain based on a crystal structure of an

78 perties of Int appear to be intrinsic to the amino-terminal domain because the phenotype of L64A was

79 r nucleoprotein complexes that form when its amino-terminal domain binds to arm-type DNA sequences th

80 An intertwined layer of amino-terminal domains bound to accessory (arm) DNAs sha

81 enhances the transcriptional activity of the amino-terminal domain by increasing the alpha-helical co

82 Our results indicate that ligand binding to amino-terminal domains can alter the behavior of synapti

83 NAP) have shown that the conformation of the amino-terminal domain changes substantially between the

84 ermine, an allosteric potentiator, opens the amino-terminal domain cleft of both the GluN2B subunit a

85 ncident replacement of the deduced cytosolic amino-terminal domain CoaT(N) with ZiaA(N) (in ziaR-(p)

86 The amino-terminal domain comprises the C-helix subdomain an

87 COP9 signalosome, eIF3) or MPN (Mpr1, Pad1, amino-terminal) domains constitute the structural core o

88 These domains, together with the amino-terminal domain, constitute a network of superheli

89 The amino-terminal domain containing the ligand recognition

90 chinery depends on the integrity of both the amino-terminal domain, containing a number of putative R

91 The rest of the amino-terminal domain contains a large number of possibl

92 The amino-terminal domain contains four CXXXC sequence repea

93 s and found that only the construct with the amino-terminal domain deleted, Hsp93-DeltaN, had reduced

94 and binding of allosteric modulators to the amino-terminal domain determine the open probability of

95 , binds at the interface of the GluN1/GluN2B amino terminal domain dimer by an induced-fit mechanism.

96 We show how Cbln1 hexamers "anchor" GluD2 amino-terminal domain dimers to monomeric beta-NRX1.

97 -associated protein and demonstrate that its amino-terminal domain disengages p53 from Numb, triggeri

98 ging charge or polarity), while those in the amino-terminal domains exhibited neither a preponderance

99 rmore, the Arabidopsis HDR contains an extra amino-terminal domain following the transit peptide that

100 rix protein Megator requires its coiled-coil amino-terminal domain for spindle matrix localization, s

101 epresented three related groups, whereas the amino-terminal domains formed four groupings.

102 spectroscopy that the Escherichia coli NusG amino-terminal domain forms a complex with the acidic re

103 how allosteric inhibitors, acting within the amino terminal domain, further stabilize the LBD layer.

104 40 (Cx40) gap junctions, and two cytoplasmic amino-terminal domain glutamate residues are essential f

105 ress the problem, we generated the GPIbalpha amino terminal domain (GPIbalpha-N) fully sulfated on th

106 Pairwise comparisons between Kunitz and amino-terminal domain groups demonstrated that dN was co

107 Hh signalling is mediated by its amino-terminal domain (HhN), which is dually lipidated a

108 This region of the protein includes the amino-terminal domain I as well as the subsequent linker

109 the crystal structure of the well-conserved amino-terminal domain I has been determined.

110 demonstrated that phosphorylation within the amino-terminal domain I is essential for transcription,

111 In correlation, a series of deletions in the amino-terminal domain impair nuclear as well as cytoplas

112 the interface of the ligand binding and the amino terminal domains in a homology model of GluN1/GluN

113 ny unresolved issues include the role of the amino-terminal domain in AMPA receptor signaling and the

114 and 349-402 for synaptic suppression, while amino-terminal domains including NLS1 are dispensable.

115 r the suppression of axonal branching, while amino-terminal domains including NLS1 are dispensable.

116 by determining the solution structure of its amino-terminal domain (Int(N), residues Met1 to Leu64) i

117 d and twisted fashion through interdigitated amino-terminal domain interactions, form a kinked centra

118 inal DNA binding domain and a less conserved amino-terminal domain involved in binding small-molecule

119 y interaction between carboxyl and hexameric amino terminal domains is shown to generate the curvatur

120 anine-rich kinase (SPAK) binding site in the amino-terminal domain is conserved.

121 One protein that binds Rb1 through the amino-terminal domain is encoded by Thoc1, a required co

122 Our results suggest that, whereas the amino-terminal domain is essential for primary interacti

123 with the inner envelope membrane through its amino-terminal domain is important for the functions of

124 rR with only one active site cysteine in the amino-terminal domain is inactivated at rates comparable

125 The amino-terminal domain is inserted by the YidC pathway wh

126 The P protein amino-terminal domain is natively unfolded; to probe its

127 We show that the amino-terminal domain is not a simple "accessory" elemen

128 The FliG amino-terminal domain is organized in a regular array wi

129 Indeed, when this amino-terminal domain is removed, the protein is retaine

130 binds to m(6)A-containing mRNA, whereas the amino-terminal domain is responsible for the localizatio

131 which encodes a 21-amino-acid insert in the amino-terminal domain, is a key determinant of GluN1/Glu

132 length hTDP-43, but not a mutant lacking its amino-terminal domain, led to progressive loss of ommati

133 ls when the lethal factor (LF) binds via its amino-terminal domain, LF(N), to oligomeric forms of act

134 force for translocation of LF, EF and the LF amino-terminal domain (LFN) through the PA63 pore.

135 ences in the conformational stability of the amino-terminal domain mediate neurodegeneration.

136 DG-like TNKS-interacting motifs in the EBNA1 amino-terminal domain mediated binding with the ankyrin

137 employing recombinant human mGlu2/3 receptor amino terminal domains, molecular modeling, and site-dir

138 the potential LPS-binding site(s) within the amino-terminal domain, mutations were introduced into C1

139 merlin truncation mutants with impaired GST-amino-terminal domain (N-term or NTD)/GST-carboxy-termin

140 , PrP(Sc) We examined the role of the PrP(c) amino-terminal domain (N-terminal domain [NTD], amino ac

141 m rabbits immunized with the non-collagenous amino-terminal domain (NC1) of human type VII collagen,

142 rate that plasmin can cleave the native NR2A amino-terminal domain (NR2A(ATD)), removing the function

143 r with each protomer containing an L30e-like amino-terminal domain (NTD) and a SPOUT methyltransferas

144 re clearly define the roles of the HTLV-1 CA amino-terminal domain (NTD) and CA CTD in particle bioge

145 a methionine residue at the junction of the amino-terminal domain (NTD) and the carboxy-terminal dom

146 HIV-1 capsid protein contains an amino-terminal domain (NTD) comprising seven alpha-helic

147 mitotic CDK, Clb2/Cdc28, binds tightly to an amino-terminal domain (NTD) of Cdc6, and that Cdc6 in th

148 tains a proteolytically processed 38-residue amino-terminal domain (NTD) that is essential for basal-

149 g motifs and an approximately 200-amino acid amino-terminal domain (NTD) with known functions includi

150 e we identify missense mutations in Hsp104's amino-terminal domain (NTD), which is conserved among Hs

151 iptional activation functions in the LBD and amino-terminal domain (NTD).

152 architectural diversity involving additional amino-terminal domains (NTDs).

153 has additional cellular targets besides the amino terminal domain of clathrin and thus cannot be use

154 r of the interaction of amphiphysin with the amino terminal domain of clathrin, and shown to inhibit

155 e residues, E9 and E13, from the cytoplasmic amino terminal domain of Cx40 with the corresponding lys

156 Leu22 resides within the 8 kDa amino terminal domain of DNA polymerase beta, which exhi

157 Finally, addition of excess amino terminal domain of galectin-3 inhibited incorporat

158 We created a series of mutants within the amino terminal domain of GluN1 that change patient antib

159 udies have added S1PR2 as a receptor for the amino terminal domain of Nogo-A, and have demonstrated s

160 n to the E or K 9 and 13 loci located on the amino terminal domain of these two connexins.

161 Cocrystallization of 14a with the amino terminal domains of hmGlu2 and hmGlu3 combined wit

162 tedly, the structural similarity between the amino-terminal domain of 10-formyltetrahydrofolate dehyd

163 The unusually long amino-terminal domain of 550 residues that precedes the

164 The amino-terminal domain of A20, which is a de-ubiquitinati

165 Our crystal structure of the amino-terminal domain of an archaeal AAA ATPase of unkno

166 the virulent strain H37Rv, in contrast, the amino-terminal domain of annexin-1 was removed by proteo

167 creasing the conformational stability of the amino-terminal domain of apoE increased aggregation rate

168 endoplasmic reticulum, lysines in the short amino-terminal domain of BST2 are ubiquitinated by K5, r

169 nteraction requires the heavily glycosylated amino-terminal domain of C1INH.

170 cysteine binding motif within helix A in the amino-terminal domain of calmodulin (CaM) that permits t

171 ructural changes that selectively modify the amino-terminal domain of CaM from those that modulate th

172 The amino-terminal domain of class B G protein-coupled recep

173 egion of natural peptide ligands bind to the amino-terminal domain of class B GPCRs, how their biolog

174 The structurally unique amino-terminal domain of class II G protein-coupled rece

175 lathrin bound to the spindle directly by the amino-terminal domain of clathrin heavy chain.

176 The amino-terminal domain of collagen type XI alpha1 chain i

177 ween the Cu(+)-metallochaperone Atx1 and the amino-terminal domain of Cu(+)-transporter PacS(N) detec

178 A soluble sulphated amino-terminal domain of DARC, but not one modified to p

179 Conversely, the expression of the amino-terminal domain of DLC-1 acts as a dominant negati

180 edicted to code for a protein containing the amino-terminal domain of DNAJB1, a homolog of the molecu

181 ne-distal immunoglobulin-variable (IgV)-like amino-terminal domain of each is crucial to these intera

182 ely weak protein-protein complex between the amino-terminal domain of enzyme I and the phosphocarrier

183 The amino-terminal domain of ExsA (NTD) is thought to mediat

184 The amino-terminal domain of FimD is observed in an ideal po

185 nteraction was disrupted by mutations in the amino-terminal domain of Gag3, which is predicted to lie

186 The amino-terminal domain of gamma(1)34.5 interacts with IKK

187 The amino-terminal domain of HCF has been proposed to form a

188 different ORF34 domains interacted with the amino-terminal domain of HIF-1alpha.

189 Second, the NS5 RdRP domain also binds the amino-terminal domain of hSTAT2.

190 Additionally, we demonstrate that the amino-terminal domain of human and bank vole PrP(c)s req

191 Fusion proteins containing the amino-terminal domain of human p14(ARF) linked to green

192 we have solved the crystal structure of the amino-terminal domain of human Su(fu)(27-268) at 2.65 A

193 o may recognize the helical structure of the amino-terminal domain of Izumo1.

194 and also show that a potential alpha-helical amino-terminal domain of LANA was important for HIF-1alp

195 erent clones contained parts of the Q/N-rich amino-terminal domain of Mca1p/Yca1p with the Sup35 part

196 ineered a partially humanized variant of the amino-terminal domain of mouse apoE (T61R mouse apoE) to

197 lex nucleated by the binding of Nam1p to the amino-terminal domain of mtRNA polymerase (Rpo41p).

198 tment on a recombinant fusion protein of the amino-terminal domain of NR2B revealed that tPA-mediated

199 n of intermolecular interactions between the amino-terminal domain of one protomer and the linker reg

200 3Kgamma revealed that only the noncatalytic, amino-terminal domain of p110gamma was necessary and suf

201 lage-associated protein is homologous to the amino-terminal domain of P3H1 and also contains four CXX

202 We find that an amino-terminal domain of PCM1 can restore ciliogenesis a

203 olated mutations in the poorly characterized amino-terminal domain of PerA which affect its ability t

204 Snu114 and the amino-terminal domain of Prp8 position U5 snRNA to inser

205 ate by hydrogen bonding to a tyrosine in the amino-terminal domain of Prp8.

206 ligand, and in this study we found that the amino-terminal domain of Rns does not form homodimers in

207 We determined the x-ray structure of the amino-terminal domain of SAS-6 from zebrafish, and we sh

208 This is analogous to a deletion of the amino-terminal domain of Sec3p, which prevents an intera

209 f human Shh, showing that a highly conserved amino-terminal domain of Shh is important for the format

210 wn assays and showed that hsp70 binds to the amino-terminal domain of SOD2.

211 ngly disrupting binding, indicating that the amino-terminal domain of Su(fu) likely impacts Gli bindi

212 t the structure is remarkably similar to the amino-terminal domain of the alpharetrovirus, avian leuk

213 e use budding yeast to show that a conserved amino-terminal domain of the Dpb2 subunit of Pol epsilon

214 e conferred by the lid region located in the amino-terminal domain of the enzymes, whereas surprising

215 in CHO cells, we show that the cleft of the amino-terminal domain of the GluN2B subunit, which has a

216 The HIV-1 matrix (MA) protein is the amino-terminal domain of the HIV-1 precursor Gag (Pr55Ga

217 The very amino-terminal domain of the huntingtin protein is direc

218 , correlates with the degree of order in the amino-terminal domain of the J protein.

219 We show that CIQ does not bind to the amino-terminal domain of the NMDA receptor and does not

220 We demonstrate that the amino-terminal domain of the normal prion protein, PrP(c

221 d ~4-kDa fragment (Arg(27)-Arg(67)) from the amino-terminal domain of the NR2B protein.

222 racil deeply within a pocket, located in the amino-terminal domain of the polymerase.

223 alpha/beta induction, but also implicate the amino-terminal domain of the protein in this function.

224 nd H-NS through interactions mediated by the amino-terminal domain of the protein.

225 tive activity mediated by the ligand-mimetic amino-terminal domain of the receptor.

226 to a three-dimensional homology model of the amino-terminal domain of the rho1 GABA(C) receptor, they

227 A homology model of the amino-terminal domain of the secretin receptor was devel

228 its located two regions in the extracellular amino-terminal domain of the subunit: the E loop (a loop

229 The amino-terminal domain of the VEEV capsid protein contain

230 Understanding of the conformation of the amino-terminal domain of these receptors has been substa

231 ized for the cysteine-rich, disulfide-bonded amino-terminal domain of these receptors, detailed insig

232 pite recent solution of the structure of the amino-terminal domain of this receptor and that of sever

233 alcitonin covalently label the extracellular amino-terminal domain of this receptor.

234 The entire amino-terminal domain of VEEV capsid protein was found t

235 d four tyrosine phosphorylation sites in the amino-terminal domain of villin.

236 alysis of the chimeras demonstrated that the amino-terminal domain of Vpx is important for the enhanc

237 Thus, the amino-terminal domain of ZiaA inverts the metals exporte

238 elical bundle, directly interacting with the amino-terminal domains of adjacent subunits.

239 Truncation mutants showed that the amino-terminal domains of alpha(1B)- or alpha(1D)-ARs ar

240 ligand binding, usually associated with the amino-terminal domains of AraC/XylS family members.

241 To delineate the amino-terminal domains of gK involved in virus-induced c

242 udied high-affinity interactions between the amino-terminal domains of GluA2 and GluA3 AMPA receptors

243 ts in proteasome-mediated degradation of the amino-terminal domains of NLRP1B, liberating a carboxyl-

244 The amino-terminal domains of NMDA receptor subunits are imp

245 rovided a platform for further dissection of amino-terminal domains of nsp3.

246 Our findings suggest that the amino-terminal domains of other F box proteins might als

247 d on high resolution structures reported for amino-terminal domains of other family members.

248 C1ql2 and C1ql3 specifically bound the amino-terminal domains of postsynaptic GluK2 and GluK4 K

249 Although NMR and crystal structures of amino-terminal domains of several family members support

250 ere the actions of two proteases release the amino-terminal domains of SREBPs that travel to the nucl

251 -RAG2 heterotetramer is 'Y-shaped', with the amino-terminal domains of the two RAG1 chains forming an

252 nd-binding cleft within the disulfide-bonded amino-terminal domains of these receptors, with the pept

253 n contrast, substitution of either the GLUT4 amino-terminal domain or the large cytoplasmic loop betw

254 These results imply that nsP4's amino-terminal domain participates in distinct interacti

255 a more extensive set of interactions in the amino-terminal domain plays some role in the actions of

256 It spans both ribosomal subunits with its amino-terminal domain positioned adjacent to the aminoac

257 The position of the FlAsH label in the amino-terminal domain provides a signal for monitoring i

258 Mutations in the amino-terminal domain reduced the formation of fluoresce

259 members and may help to orient the receptor amino-terminal domain relative to its helical bundle reg

260 nteraction and cell-to-cell movement and the amino-terminal domain required for importin-alpha intera

261 crystal structure at 2.4 A resolution of the amino-terminal domain (residues 30-340) of human symplek

262 owledge of the structure and function of the amino-terminal domains reviewed here may enable targetin

263 P, V, and W, have in common an amino-terminal domain sufficient to bind STAT1, inhibiti

264 tization is accompanied by disruption of the amino-terminal domain tetramer in AMPA, but not kainate,

265 , the detailed conformational changes in the amino-terminal domain that accompany ATP binding, and th

266 rminal ends of the Gli proteins and a unique amino-terminal domain that binds the carboxy-terminal ta

267 imals are structurally conserved and have an amino-terminal domain that functions in transport and a

268 dyad protease, with the Lys recruited to the amino-terminal domain that is itself not present in most

269 ding sites located within the noncollagenous amino-terminal domain that may play a role in the functi

270 TRF2 possesses an amino-terminal domain that plays an essential role in pr

271 ydrogenase domain, but rather depends on the amino-terminal domain that recruits PXDLS containing tar

272 oint mutation in AtTPS6 encoding a conserved amino-terminal domain, thought to catalyze trehalose-6-p

273 ring-shaped hexameric self-assemblies via an amino-terminal domain through its phosphorylation or lig

274 of the N-methyl-d-aspartate (NMDA) receptor amino terminal domain to explore the binding mode of mul

275 DNA binding protein that binds via its small amino-terminal domain to high affinity arm-type DNA site

276 of helix A associated with activation of the amino-terminal domain to promote high-affinity binding t

277 tes of the Holliday junction DNA and via its amino-terminal domains to distal "arm-type" sites.

278 However, the amino terminal domain, transmembrane, and cytoplasmic re

279 ter to its binding site in the extracellular amino-terminal domain triggers structural changes in dis

280 In a proposed model for AMPAR assembly, the amino-terminal domain underlies the formation of a dimer

281 A stretch of the amino-terminal domain unique to centrins appears disorde

282 The biochemical composition of the amino-terminal domain varies due to alternative splicing

283 dence that the inherent conformations of the amino-terminal domains vary based on the subunit and mat

284 e demonstrate that peptides corresponding to amino terminal domains VI and V of netrin-1 repel migrat

285 cretin receptors in which all or part of the amino-terminal domain was deleted.

286 In this study, the HTLV-1 capsid amino-terminal domain was found to provide distinct cont

287 (125) within the same region of the receptor amino-terminal domain was identified as the site of labe

288 We found that although the amino-terminal domain was sufficient for origin-dependen

289 h the mammalian retromer complex through its amino terminal domain, whereas SNX2 does not.

290 s heavily glycosylated domains to expose the amino-terminal domain, which is a ligand for NPC1 and re

291 es with differing specificities and that the amino-terminal domain, which is unique to this class of

292 resolve the crystal structure of ACF7's NT (amino-terminal) domain, which mediates F-actin interacti

293 of the MCM complex specifically bound to the amino-terminal domain, while MCM6 bound to both the amin

294 28 AtCHX genes after revision consists of an amino-terminal domain with 10 to 12 transmembrane spans

295 The amino-terminal domain with a fold distinct among known T

296 ylation by PAC-1 requires association of its amino-terminal domain with ERK2 that results in catalyti

297 V shares the amino-terminal domain with P but has a zinc-binding carb

298 These data suggest that interactions of the amino-terminal domain with the rest of the PrP(c) molecu

299 This region of interaction of peptide amino-terminal domains with the receptor may provide a p

300 The zinc site on the amino-terminal domain (ZiaA(N)) of the P(1)-type zinc-tr