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1 m combining lysine export and catabolism via aminoadipate.
2 amate transport was not inhibited by L-alpha-aminoadipate.
3                                      L-alpha-Aminoadipate (1 mM) inhibited uptake by only 25 +/- 4%.
4 6-hydroxyhomoarginine yields guanidine and 2-aminoadipate-6-semialdehyde.
5                   We now report that L-alpha-aminoadipate also blocks or reverses the persistent depo
6 cal to glutamine transaminase K (GTK), alpha-aminoadipate aminotransferase, and mitochondrial asparta
7 d converts two plant endogenous amino acids, aminoadipate and tryptophan, to their respective N-acety
8 esis of lysine, enzymatic reduction of alpha-aminoadipate at C6 to the semialdehyde, requires two gen
9 at exposure of hippocampal slices to L-alpha-aminoadipate blocks or reverses quisqualate sensitizatio
10 ate reductase but more likely is oxidized to aminoadipate by aldehyde dehydrogenase ALDH7B in vivo.
11    Moreover, the pipecolate catabolite alpha-aminoadipate decreased 30-fold in RNA interference plant
12 ADPH) to the free enzyme followed by L-alpha-aminoadipate-delta-semialdehyde ( L-AASA) which adds in
13 .1.10] catalyzes the condensation of l-alpha-aminoadipate-delta-semialdehyde (AASA) with l-glutamate
14 LKR, and subsequently to glutamate and alpha-aminoadipate-delta-semialdehyde by SDH.
15 mM-1 min-1) at 16% the efficiency of L-alpha-aminoadipate in [32P]PPi/ATP exchange assays.
16 ism of the selective gliotoxicity of L-alpha-aminoadipate (L-alpha AA) is thought to involve its entr
17 ein S6:glutamate ligase and a putative alpha-aminoadipate ligase, defining the first group of ATP-gra
18 nal neurons and photoreceptor cells by alpha-aminoadipate or glutamate signaling.
19 phylogenetic comparisons show that the alpha-aminoadipate pathway enzyme is an outgroup to all aconit
20 yzes one of the regulated steps of the alpha-aminoadipate pathway for lysine biosynthesis in fungi.
21                                    The alpha-aminoadipate pathway for lysine biosynthesis is present
22 s catalyze hydrolyase reactions in the alpha-aminoadipate pathway for lysine biosynthesis or the 2-ox
23 ) catalyzes the fourth reaction of the alpha-aminoadipate pathway for lysine biosynthesis, the conver
24 ming)] catalyzes the final step in the alpha-aminoadipate pathway for lysine biosynthesis.
25                                    The alpha-aminoadipate pathway of lysine biosynthesis is modulated
26                The first enzyme in the alpha-aminoadipate pathway, homocitrate synthase (HCS), is the
27 cerevisiae together encode the 180-kDa alpha-aminoadipate reductase (AAR) in the biosynthetic pathway
28                                    The alpha-aminoadipate reductase (AAR) of this pathway catalyzes t
29  Lys5 covalently primes Lys2, allowing alpha-aminoadipate reductase activity by holo-Lys2 with cataly
30 ministration of an astroglial toxin, l-alpha-aminoadipate, reversed mechanical allodynia.
31                                        alpha-aminoadipate semialdehyde and gamma-glutamate semialdehy
32 ted in phosphopantetheinylation of the alpha-aminoadipate semialdehyde dehydrogenase involved in lysi
33 ed it to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde.
34 d the most likely MSI target genes to be the aminoadipate-semialdehyde dehydrogenase AASDH and the so
35 egradation pathway by CRISPR deletion of the aminoadipate-semialdehyde synthase (Aass) gene.
36           The effects of glutamate and alpha-aminoadipate were also determined in purified Muller cel
37                                        alpha-Aminoadipate, which selectively target glial cells, also
38 trations of glutamate and its analogue alpha-aminoadipate, which specifically binds Muller glia, were