ライフサイエンスコーパス: amplification

1 hinery catalyzing a click reaction (= signal amplification).

2 forms the beam splitter linear coupling into amplification.

3 of the structural diversity observed in MYCN amplification.

4 cell proliferation in response to centrosome amplification.

5 ular machinery for auditory transduction and amplification.

6 the host cell restrictions which limit their amplification.

7 te the importance of the droplet geometry to amplification.

8 ver small R surprisingly counteracts further amplification.

9 emto-molar detection limit without enzymatic amplification.

10 d a specific minimum threshold for efficient amplification.

11 of RNA splicing without biases introduced by amplification.

12 high expression is not caused by mutation or amplification.

13 hich was deemed to underlie feature-specific amplification.

14 ter output indicating that MBIII limits over-amplification.

15 ranscriptional modifications and bias due to amplification.

16 irus 2 (EcPV2) infection, detected using PCR amplification.

17 ration changes as may occur in visual signal amplification.

18 SABER provides an additional 7.6-fold signal amplification.

19 as hyperbranching and/or enzymatic digestion/amplification.

20 e biology, albeit with some scope for clonal amplification.

21 ences are frequently dependent upon Met gene amplification.

22 cers were not driven by ecDNA-based oncogene amplification.

23 nown how normalization arises from recurrent amplification.

24 particle (CNT-AuNP) nanoclusters, for signal amplification.

25 the number of centrioles revealing centriole amplification.

26 nd all patients with centrally confirmed MET amplification.

27 as ddPCR, sequencing, and clamped enzymatic amplification.

28 tigate a potential mechanism of non-specific amplification.

29 nuclear compartment through "gene expression amplification."

30 c complexity, 1q21-q44 gains, 2p16/REL gains/amplifications, 19p13/CD70 homozygous deletions, and TP5

31 The quasi single-molecule amplification achieved via ePCR represents the fundament

32 Local recurrent circuits could implement amplification, allowing pattern completion and other com

33 Mathematical modelling shows that amplifications also tune gene expression in stochastic e

34 pies increases with increasing levels of MET amplification, although no consensus exists on the optim

35 cal and biochemical sensing, separations and amplification, among others.

36 fined space and thereby facilitating the HCR amplification analysis of cytoplasmic TR.

37 etecting genomic alterations, high-level MET amplification and activating MET mutations or fusions ar

38 y quantitative and qualitative 16S rRNA gene amplification and amplicon sequencing.

39 voltage (in-spite of the local differential amplification and charge enhancement).

40 luence of probe length and sample age on PCR amplification and co-expression of candidate genes on ap

41 sms by which this is accomplished include AR amplification and expression of AR splice variants, demo

42 he ribonuclease to specifically initiate DNA amplification and generate strong fluorescence signals.

43 e is a mutational process that produces gene amplification and genome instability.

44 Unlike in most neurons, amplification and impulse generation by voltage-gated ch

45 RP, 400 HRPs) labels to provide large signal amplification and limits of detection in the sub-fg mL(-

46 ovel method for multiplexing, referred to as amplification and melting curve analysis (AMCA), which l

47 The advantage conferred by NOTCH1 amplification and overexpression can be explained by NOT

48 alterations, with heterogeneous NOTCH1 gene amplification and overexpression that also occur, to a l

49 me relevant physical processes (e.g., Arctic amplification and polar vortex movement) that likely con

50 ein filaments are the main driving force for amplification and propagation of pathology in synucleino

51 Nearly full-length proviral amplification and sequencing (NFL-PAS) were performed at

52 Through nearly full-length proviral amplification and sequencing (NFL-PAS), we generated 733

53 of pediatric blood culture bottles; 16SrDNA amplification and sequencing (panbacterial PCR) for dete

54 eveloped to detect and identify, through PCR amplification and sequencing of the 16S-rRNA gene, the p

55 tions in these gliomas including mutant EGFR amplifications and Sub1, Trp53, and Tead2 loss-of-functi

56 anisms of DNA metabolism (replication cycle, amplification) and the genomeediting tool CRISPR-Cas9 ar

57 three major steps: nucleic acid extraction, amplification, and amplicon detection.

58 sentations including sex, neuroblastoma MYCN amplification, and cell types.

59 testing that involves sampling, extraction, amplification, and detection is simply operated on a sin

60 diverse drawbacks including erroneous target amplification, and the limited stability of protein enzy

61 ineage-specific X-Y coevolution through gene amplification, and the selfish forces underlying this ph

62 nalysis reliably detects relevant mutations, amplifications, and chromosomal copy number changes in r

63 amplification or protein-enzyme based signal amplification are highly relevant, yet still plagued by

64 (BCID-GP) Panel is a multiplex nucleic acid amplification assay based on competitive DNA hybridizati

65 in resource-limited areas, an isothermal DNA amplification assay based on recombinase polymerase ampl

66 Isothermal amplification assays, such as loop-mediated isothermal a

67 y 20 years, and only one report of Brillouin amplification beyond 1 TW.

68 ent of DNA excision outcomes that is free of amplification bias.

69 f noise owing to incomplete RNA capture, PCR amplification biases and/or batch effects specific to th

70 Moreover, we observed that amplification biases encountered in single-cell WGS expe

71 Herein, we developed a dual-amplification-boosted, translational electrochemical bio

72 rrent excitation enhances sensory signals by amplification, but only for subnetworks with increased c

73 Signal amplification by reversible exchange (SABRE) is a hyperp

74 oresis, the single polymerase created a dual amplification by target-recycling and generation of an c

75 Circle-to-circle amplification (C2CA) is a specific and precise cascade n

76 Parameter regimes achieving directional amplification can be elegantly obtained from a topologic

77 age laser based on traditional chirped pulse amplification capable of producing 4 mJ, near-transform

78 ng researchers to instead utilize isothermal amplification, conducted at a single temperature, as an

79 ole of early negative feedback and necessary amplification conferred by late positive feedback.

80 Focal chromosomal amplification contributes to the initiation of cancer by

81 These include internal amplification controls to account for false-negative rea

82 40% of cancer cells and that MYC copy number amplification correlates with enhanced transcriptional o

83 Recurrent amplification could be solely due to positive selection

84 e manufacturer's criteria for successful pre-amplification (Ct values <= 35 for unamplified cDNA) had

85 methods, by virtue of the information in the amplification curve.

86 kinetics of PCR reactions is encoded in the amplification curve.

87 lie in the exponential growth region on the amplification curves for all reactions in a dilution ser

88 Following one asexual amplification cycle in the liver, parasites reach high b

89 verages the kinetic information in real-time amplification data and the thermodynamic melting profile

90 Here, we report a mechanism of gene amplification due to a translocatable unit (TU) excising

91 = 0: no constitutive activity, gamma = 1: no amplification (E(max)-type fitting), and epsilon = 1: no

92 of the energetics governing these chirality amplification effects.

93 recently proposed method for estimating qPCR amplification efficiency E analyzes fluorescence intensi

94 Although C2CA provides a high amplification efficiency with a negligible increase of f

95 These ultra-quantification methods for LAMP amplification either singularly or in combination have p

96 hia coli, we show that gene duplications and amplifications enable adaptation to fluctuating environm

97 tant double-layer properties, such as charge amplification, energy storage, and differential capacita

98 embly, streptavidin/biotin complex, antibody amplification, enzymatic reactions, triplex structure fo

99 based on an enhanced recombinase polymerase amplification (eRPA) reaction.

100 some isolates, subsequent or coincident gene-amplification events augment resistance.

101 pproach to analyze approximately 1.2 million amplification events.

102 ) as the primary driver of focal copy number amplification (fCNA) - enabling gene amplification, rapi

103 ad to be replaced by (3) proofing linear pre-amplification for each gene, thus, increasing the number

104 eat challenge and require substantial signal amplification for the accurate and precise quantificatio

105 Nucleic acid amplification for the detection of severe acute respirat

106 ofluidic technologies have enabled rapid and amplification-free detection of DNA with a high signal-t

107 We confirmed that the amplification frequencies of MYC, YAP1 and MMP13 were el

108 only 3 molecules per partition represents an amplification frequency of greater than 95 percent.

109 ing copy number, closely associated with the amplification frequency.

110 (SABRE) that includes parameters for Signal Amplification (gamma), Binding affinity (K(d)), Receptor

111 t of genomic technologies, recurrent genomic amplification has been mapped throughout the genome.

112 Film assembly (LFA) serves as a platform for amplification, hybridization, washing, and fluorescent i

113 t normalization in V1 operates via recurrent amplification, i.e., amplifying weak inputs more than st

114 al preferences selected for during for their amplification.IMPORTANCE Copyback defective virus genome

115 40% of patients showed amplification in ADAR gene and there was a positive corr

116 Signal amplification in biological systems is achieved by coope

117 ation of cough and fever/chills has 4.2-fold amplification in COVID(pos) patients during the week pri

118 decay due to multi-excitonic nature of light amplification in II-VI semiconductor nanocrystals.

119 vides insight into specific and non-specific amplification in LAMP that are difficult to deduce from

120 gnature of each target by performing digital amplification in microfluidic droplets.

121 reased transduction gain, reflecting smaller amplification in the G-protein cascade; (2) a faster rat

122 Despite the presence of cyclin D1 amplification in the PDXC line, palbociclib treatment ha

123 ncer cells harboring genomic PD-L1 and PD-L2 amplification in the second.

124 Another group has shown EGFR and MDM2/MDM4 amplifications in patients with HPD.

125 seasonal cycles are associated with similar amplifications in the atmospheric vertical and horizonta

126 Downsides of multiple displacement amplification include coverage biases and exacerbation o

127 Chromosomal 7p12 amplification, including the genes HUS1, EGFR, ABCA13, a

128 to 32% (65/203) of insertions, whereas over-amplification increased false positive calls.

129 at accelerates genomic DNA rearrangement and amplification into ecDNA and enables rapid acquisition o

130 Here, we show that gene amplification is an additional evasion mechanism used by

131 (1) It is not known if this amplification is an intrinsic property of all calcium-re

132 Centrosome amplification is frequently observed in tumors, where it

133 However, photonic amplification is generally tied to high optical contrast

134 PIV5) replication, but that their subsequent amplification is restricted by the induction of innate i

135 roblastoma, a pediatric cancer in which MYCN amplification is strongly associated with unfavorable ou

136 bining loop-mediated isothermal nucleic acid amplification (LAMP) and bioluminescent assay in real ti

137 ification metrics for use with loop-mediated amplification (LAMP) as a bridge between concentrated an

138 hanced colorimetric loop-mediated isothermal amplification (LAMP) assay and smartphone-based color an

139 In this study, a loop-mediated isothermal amplification (LAMP) assay was designed for the specific

140 tive samples, while loop-mediated isothermal amplification (LAMP) detected 2/10.

141 to perform digital loop-mediated isothermal amplification (LAMP) for the detection and quantificatio

142 d and simplicity of loop-mediated isothermal amplification (LAMP) for the detection of the BRAF V600E

143 y (PD) detection of loop-mediated isothermal amplification (LAMP) targeting the waterborne pathogen V

144 pports the usage of loop-mediated isothermal amplification (LAMP) to detect PIK3CA c.3140 A > G (H104

145 Loop-mediated isothermal amplification (LAMP) was compared to traditional rapid d

146 py, placental blood loop-mediated isothermal amplification (LAMP), and placental histopathology.

147 ain reaction (PCR), loop-mediated isothermal amplification (LAMP), and reverse transcription (RT).

148 ion assays, such as loop-mediated isothermal amplification (LAMP), show great utility for the develop

149 By coupling with loop-mediated isothermal amplification (LAMP), the CHB probe could detect Borreli

150 PvDBP gene amplification leads to increased mRNA levels and protect

151 Together, our data indicate that amplification leads to over expression of ADAR and it co

152 between four individual NA12878 cells; under-amplification limited detection to 32% (65/203) of inser

153 al effector functions in endosomes to a PI3K amplification loop at the cell surface.

154 llular proteins, ATM and KAP1, a lytic cycle amplification loop is established, and disruption of thi

155 e 4 disease > 1 year or stage 4/4S with MYCN amplification < 1 year who had completed induction witho

156 In conclusion, 7p12 amplification may predict nonresponse to NAC and worse s

157 ibodies (which already has a built-in signal amplification mechanism), QD-SABER provides an additiona

158 ilities requires a full understanding of the amplification mechanisms.

159 This amplification-mediated gene expression tuning (AMGET) oc

160 Using linear amplification-mediated PCR, we successfully map the UBC-

161 a specific and precise cascade nucleic acid amplification method consisting of more than one round o

162 rapid, easy-to-use loop-mediated isothermal amplification method for qualitative detection of CMV DN

163 Various signal amplification methods can overcome the limitation of SPR

164 obtained using highly novel chemical signal amplification methods demonstrating a standard deviation

165 as been a growing interest in combining such amplification methods with POC detection methods to enab

166 in all electronic devices, and enable signal amplification, modulation, and relay.

167 f MET-targeted therapies in cancers with MET amplification, mutation and fusion, and MET overexpressi

168 By incorporating additional data (amplification, mutation, DNA methylation, chromatin acce

169 Patients' tumors harbored FGFR1 or FGFR2 amplification (n = 20), FGFR2 or FGFR3 single-nucleotide

170 with isothermal nucleic acid sequence based amplification (NASBA), the assay was able to detect ampl

171 proposed nicking-assisted enzymatic cascade amplification (NECA) comprises an on-loop amplification

172 microsatellites in order to reduce in vitro amplification noise.

173 Here we demonstrate that similar activity amplification occurs in mice, and that this is related t

174 Raman or Brillouin amplification of a laser beam in plasma has long been se

175 However, no significant plasma-based Raman amplification of a laser pulse beyond 0.1 TW has been ac

176 escribes the first observation of pronounced amplification of absorption in low contrast opals formed

177 and 99.9% of target DNA reads and successful amplification of all target regions by up to 15 forward

178 ological responsiveness is underlain by both amplification of ancestral nutrition-responsive gene exp

179 Cochlear amplification of basilar membrane traveling waves is tho

180 at decisions to expend effort are related to amplification of benefit-versus-cost information attende

181 on coincidence detection relies on nonlinear amplification of changes in the decay of dendritic synap

182 Amplification of chirality as probed by varying the amou

183 Such an enhancement in the amplification of chirality is only achieved by mixing th

184 tify the most robust techniques for enhanced amplification of DNA libraries.

185 By following the replication and amplification of DVGs in A549 cells that are deficient i

186 ange of concentrations, showing a remarkable amplification of efficiency at high concentrations.

187 In summary, these studies demonstrate that amplification of ERK1/2 signaling in KRAS-mutated colore

188 Amplification of HER2 gene (ERBB2) and overexpression of

189 lumes, especially in adults, due to regional amplification of heterogeneous flow.

190 t the poly(A)+-tail and (2) introduced a pre-amplification of human RNA before qRT-PCR.

191 Here, we report a method for the amplification of imaging contrast in tumours via the tem

192 Mutations and amplification of KIT are also common.

193 re of RETrace was the introduction of linear amplification of microsatellites in order to reduce in v

194 at immune cell exclusion was associated with amplification of Myc target genes and increased expressi

195 These results demonstrate that amplification of natural selection depends on the specif

196 Rs, resulting in de novo synthesis of Cxcl2, amplification of neutrophil recruitment, and potentiatio

197 reaction (LRPCR) assay for efficient genome amplification of NiV, HeV, and a related non-pathogenic

198 Clonal amplification of one or a few viral sequences accounted

199 Active amplification of organized synaptic inputs in dendrites

200 Due to the amplification of probes, amplicons can be visualized wit

201 equently, existing strategies using targeted amplification of rearranged variable regions comprised o

202 on the intermolecular interactions with the amplification of ring currents in stacked aggregates.

203 Amplification of single DNA molecules encapsulated in a

204 to be dominated by massive, lineage-specific amplification of testis-expressed gene families, making

205 fold and yielded far better sensitivity than amplification of the B1 sequence.

206 Sufficient Kir density enables robust amplification of the hyperpolarizing stimulus and produc

207 In neuroblastoma, amplification of the MYCN oncogene and inactivation of t

208 Amplification of the MYCN oncogene occurs in ~25% of pri

209 und that our VTM supported highly consistent amplification of the SARS-CoV-2 target (coefficient of v

210 , one-pot detection method based on two-step amplification of the signal measured by Reflective Phant

211 n of the response, reflecting a reduction in amplification of the transduction cascade; an increase i

212 tivity of the viral replicase and, thus, the amplification of the viral RNA genome.

213 ar transmission and the subsequent templated amplification of these misfolded proteins are involved i

214 Amplification of warming and loss of perennial ice cover

215 ngth of a shortest sequence of deletions and amplifications of contiguous segments that transforms on

216 idated using polymerase chain reaction (PCR) amplification, of which 167 primers gave expected PCR am

217 ssed food products and consistently detected amplification only in samples containing pork.

218 mpared with all other cancer types, and that amplification or gain of their corresponding encoding ge

219 centrations, without the need for any target amplification or protein enzymes, while operating at roo

220 Current techniques that rely on target amplification or protein-enzyme based signal amplificati

221 egy, Preparative Cellular O-Glycome Reporter/Amplification (pCORA), that introduces 4-N(3)-Bn-GalNAc(

222 amount sources of bias are the synthesis and amplification (PCR) processes.

223 Focal copy-number increases (genomic amplification) pinpoint oncogenic driver genes and thera

224 ry breaking as well as the subsequent chiral amplification process are discussed.

225 n abnormalities also reveal a range of later amplification processes that encompasses insulin resista

226 itiating events, progression mechanisms, and amplification processes.

227 c nanoparticles appears to be similar to the amplification produced by engineered zinc nanoparticles.

228 Extrachromosomal DNA (ecDNA) amplification promotes intratumoral genetic heterogeneit

229 ntrinsic instability of gene duplication and amplification provides a generic alternative to canonica

230 , which uses haplotype information to detect amplification quality in shallow coverage sequencing dat

231 number amplification (fCNA) - enabling gene amplification, rapid tumor evolution, and the rewiring o

232 Quantitative (q)PCR, rolling circle amplification (RCA) and droplet digital (dd)PCR assays w

233 padlock probe (PLP)-mediated rolling circle amplification (RCA) bioassay and an (2) agarose bead-bas

234 Rolling circle amplification (RCA) is frequently applied for fluorescen

235 e developed and evaluated the rolling circle amplification (RCA) products that are based on anti-CD40

236 onstrated assay consists of a rolling circle amplification (RCA) technique, responsible for the gener

237 of padlock probe ligation and rolling circle amplification (RCA).

238 amplicons during a loop-mediated isothermal amplification reaction in real-time.

239 We herein demonstrate an RCA-based cascade amplification reaction that converts a side-reaction to

240 de amplification (NECA) comprises an on-loop amplification reaction using circular templates to gener

241 rate intermediate amplicons, and an off-loop amplification reaction using intermediate amplicons as p

242 Chirality amplification refers to the ability of a small chiral bi

243 Herbivore-associated bacterial amplification reflects community-wide compositional shif

244 The concept that there is a single "cochlear amplification region" needs to be revised.

245 , the pathophysiology of tumors without MYCN amplification remains poorly defined.

246 th the extremely high degrees of exponential amplification required for single cell amounts of RNA.

247 EcDNA amplifications resulted in higher levels of oncogene tra

248 In the DAMR system, recombinase polymerase amplification (RPA) and CRISPR-Cas12a derived fluorescen

249 cular assays based on recombinase polymerase amplification (RPA) for the detection of pork and horse

250 cation assay based on recombinase polymerase amplification (RPA) was developed.

251 RISPR-Cas13a and RT-loop-mediated isothermal amplification (RT-LAMP).

252 on, amenability to be interfaced with signal amplification schemes, and inherent biocompatibility.

253 We used single-genome amplification (SGA) in cross-sectional and longitudinal

254 Single-genome amplification (SGA) was used to generate partial HIV-1 p

255 ng squamous tumors, while tumors with ALAL-1 amplification show lower infiltration of several types o

256 Here we report a very efficient single amplification stage laser based on traditional chirped p

257 detection in sera from patients without any amplification step (e.g., PCR) required, thus simplifyin

258 with the addition of a 10-minute isothermal amplification step, and is further demonstrated using a

259 the femtomolar range without any target pre-amplification step.

260 Actually, label-based signal amplification strategies of SPR platforms including nano

261 ted procedures requiring technically complex amplification strategies such as hyperbranching and/or e

262 NTs and AuNPs, represents a promising signal amplification strategy for achieving a sensitive biosens

263 acids that can be analyzed via nucleic acid amplification techniques has several advantages, includi

264 igh-throughput, fully automated nucleic acid amplification test system for the detection of SARS-CoV-

265 d a positive stool C. difficile nucleic acid amplification test were enrolled.

266 men who have sex with men with nucleic acid amplification test-diagnosed pharyngeal gonorrhea in a s

267 gnificant diarrhea and positive nucleic acid amplification testing (NAAT) and received CDI treatment.

268 ctively, after 48 h compared to nucleic acid amplification testing (NAAT).

269 Digital nucleic acid amplification tests (digital NAATs) have emerged as a po

270 Nucleic acid amplification tests (NAATs) are the primary means of ide

271 ent and maturation of automated nucleic acid amplification tests (NAATs) has greatly improved the ass

272 Nucleic acid amplification tests (NAATs) such as real-time PCR demons

273 immunohistochemistry (IHC), and nucleic acid amplification tests (NAATs).

274 Highly sensitive and specific nucleic acid amplification tests have become the diagnostic reference

275 Focal amplifications that affected chromosomes 1q21 (which enc

276 Intrachromosomal amplifications that formed initially under low-level dru

277 ically relevant as mutations, deletions, and amplifications that increase CDK4/6 activity contribute

278 reverse transcribe mRNA, followed by linear amplification through in vitro transcription.

279 odings from being decoded, whereas escalated amplification through the recruitment of second-order ne

280 en the door to efficient Raman and Brillouin amplification to petawatt powers and Joule-level energie

281 of electromagnetic canyons and non-resonance amplification, to directly view on a widefield microscop

282 In non-transformed cells, centrosome amplification triggers PIDDosome activation as a protect

283 We used tyramide signal amplification (TSA) and label-free mass spectrometry (MS

284 resolve this disparity, by showing that any amplification under death-Birth updating is necessarily

285 escence detection of nucleic acid isothermal amplification utilizing energy-transfer-tagged oligonucl

286 tation at high latitudes enhances the Arctic amplification via remote and time-delayed physiological

287 ially druggable genetic alterations, and MET amplification was associated with complete tumor respons

288 ability assay, and protein-misfolding cyclic amplification, we monitored the conformational and pheno

289 commercially available kits for Whole Genome Amplification (WGA), PicoPLEX and RepliG were compared o

290 conserved MYC-Box regions I and II impaired amplification, whereas MYC-box III mutations delivered h

291 n that converts a side-reaction to secondary amplification, which improves the detection limit and si

292 e is enhanced with an increase in the charge amplification, which is the absorption of ions on a like

293 through polymerase slippage inherent in DNA amplification, which we characterized to be approximatel

294 Saccharomyces cerevisiae tolerate chromosome amplification while laboratory strains used as a model f

295 sub-nA gate currents, and offer ion current amplification with a gain up to ~300.

296 ow efficient PDT-mediated antitumor immunity amplification with an ultra-low dose (0.25 mug kg(-1) ),

297 ors to implement normalization via recurrent amplification with arbitrary normalization weights, some

298 Isothermal DNA amplification with bioluminescent detection is a fast, l

299 Following PCR amplification with indexing primers, the subnucleosome-s

300 luding the measles virus, to promote massive amplification within the host, followed by efficient aer