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3 g was associated with increased striatal and amygdalar activation in the anticipation of losses, and
5 tion of IM has the opposite effect, allowing amygdalar activation of autonomic structures and emotion
9 related neurobiological activity (ie, higher amygdalar activity [AmygA]) and higher risk of major adv
13 at not all fear instances lead to heightened amygdalar activity and, instead, point to roles of the a
15 f glucocorticoid hormones and the heightened amygdalar activity have been implicated in the emergence
16 tivity to subsequent cardiovascular disease, amygdalar activity independently and robustly predicted
19 ndings suggest that the growing dominance of amygdalar activity over the hippocampus during and even
21 who underwent psychometric analysis (n=13), amygdalar activity was significantly associated with art
22 lysed the relation between perceived stress, amygdalar activity, arterial inflammation, and C-reactiv
24 These results suggest that the heightened amygdalar activity, but not the elevated level of cortic
29 et of rapamycin complex 1 (mTORC1) in select amygdalar and cortical regions in rats, resulting in inc
32 e, we evaluate how cortico-striatal, cortico-amygdalar, and amygdalo-striatal projections control ext
34 d cingulate, striatal, temporal, hippocampal/amygdalar, and insular regions in the CU group compared
35 laying flight had more activity in cortical, amygdalar, and striatal motor areas, the dorsolateral po
36 projections supply information that supports amygdalar associative processes underlying acquisition o
37 minative TIA in the MGm via basolateral (BL) amygdalar axonal projections to the auditory cortex.
38 subpopulations of interneurons (INs) in the amygdalar basolateral nuclear complex (BNC) of the rat c
39 from gustatory cortical (GC) and basolateral amygdalar (BLA) neural ensembles as awake, behaving rats
40 ects revealed different patterns of gaze and amygdalar BOLD changes in ASD and NT: Individuals with A
44 e results may correspond to hypothalamic and amygdalar changes in the human condition and suggest tha
45 these nuclei participate as components of an amygdalar circuit to drive cocaine-seeking behavior prod
46 n, Ma et al. (2019) identify a novel thalamo-amygdalar circuit which uses neurotensin to initiate and
47 Our findings were anatomically specific to amygdalar circuitry in that individual differences in so
49 and social behaviors, many of which involve amygdalar circuits, are hallmarks of adolescence in many
50 hown to be critical regulatory components of amygdalar circuits, which control appropriate fear respo
52 hypothesized that neurons in the basolateral amygdalar complex (BLA) (lateral and basal nuclei) suppo
53 of whether NMDA receptors in the basolateral amygdalar complex (BLA) are critically involved in the e
54 imulation of ventral PAG and the basolateral amygdalar complex (BLA) evoked freezing and/or ultrasoni
56 e proposed teleost homologs of the mammalian amygdalar complex, hippocampus, striatum, preoptic area,
57 proposed teleost homologues of the mammalian amygdalar complex, hippocampus, striatum, preoptic area,
59 dorsal (A24b,c) subregions of the ACC, while amygdalar connections are more evenly distributed across
62 ontrast, they had different effects on intra-amygdalar connectivity; OXT strengthened the coupling be
64 become impaired from abnormal expression of amygdalar corticotropin-releasing hormone (CRH) and/or C
67 There were no significant differences in amygdalar CRF gene expression between stressed and handl
69 implications for understanding how discrete amygdalar CRF pathways modulate longer-lasting fear in a
75 tylation of histone H3, c-Fos induction, and amygdalar-dependent taste aversion learning is constrain
76 ese results provide additional evidence that amygdalar development is implicated in the behavioral im
79 lopment of emotional symptoms and underlying amygdalar dysfunction triggered by traumatic stress.
81 adly characterize anxiety-like behaviors and amygdalar eCB clearance enzymes in msP versus nonselecte
82 constitutive upregulation in CRF systems on amygdalar eCB function and persistent anxiety-like effec
84 vide new insights on the mechanisms by which amygdalar endocannabinoid signaling regulates emotional
85 However, although the importance of this amygdalar expression in emotion-related behavior and the
86 nhanced HPA axis inhibition, whereas reduced amygdalar expression predicts impaired stress excitation
87 xious phenotype accompanied by elevations in amygdalar FAAH activity and reduced dialysate N-arachido
88 genitors to the structures that comprise the amygdalar fear circuit including the central (CA), later
89 these findings identify the BNST as an extra-amygdalar fear circuit structure important in CO2-evoked
92 y in males are mediated by the modulation of amygdalar function by delta-9-THC and the extent of thes
94 otivated behavior, relate to hippocampal and amygdalar function, and link to pathological gambling (P
95 e hippocampus is increased through decreased amygdalar GABAergic inhibition have shown alterations of
96 an fluctuations of corticosterone, increased amygdalar glucocorticoid receptors, decreased time spent
99 a backward-masking task, which measures the amygdalar hemodynamic response to emotional faces presen
101 disorder who are trained to upregulate their amygdalar hemodynamic responses during positive autobiog
102 ietal-occipital GM and significantly reduced amygdalar, hippocampal, insular, temporal, and inferior
103 volume at 3 and 4 years of age, but not left amygdalar, hippocampal, or total cerebral volume, is ass
105 uenced by physical abuse occurred in limbic (amygdalar-hippocampal), paralimbic (cingulo-insular and
107 earning in rabbits trained immediately after amygdalar inactivation confirmed previous results with e
108 he olfactory bulb of the brain revealed that amygdalar inactivation preferentially strengthened the o
109 initiation by mating was prevented by intra-amygdalar infusion of the NMDA receptor antagonist, 2-am
114 a uniquely one-way excitatory pathway to the amygdalar inhibitory intercalated masses (IM), which inh
116 dorsal ACC was densest in deep layers, while amygdalar inputs predominantly localized in upper layers
117 its persistence and that altered hippocampal-amygdalar interaction may contribute to such pathologic
118 rful pathway that targets a special class of amygdalar intercalated mass (IM) inhibitory neurons, who
127 l signals were paired with food, control and amygdalar-lesioned rats were able to divide attention an
129 oning is partially disrupted with unilateral amygdalar lesions, but that the right amygdala has great
132 ely supports transient memory, then blocking amygdalar mAChRs should impair trace conditioning, while
133 he HR/LR extremes; this revealed that the LR amygdalar methylome was abnormal, with the HR profile mo
134 work for dissecting the functional impact of amygdalar mGluR-plasticity on fear versus anxiety in hea
135 s mood-related disorders, and interestingly, amygdalar morphology and behavior can be altered in anim
136 ning was indicated by the finding that intra-amygdalar muscimol failed to disrupt performance of the
139 ical thickness, amygdala volume, and cortico-amygdalar network correlates of externalizing behavior i
141 Together, these results suggest that the amygdalar neuronal activity during stress, but not short
142 rontal cortical, medial dorsal thalamic, and amygdalar neuronal response profiles and learning-relate
143 leus of the amygdala was given to inactivate amygdalar neurons at each of three stages of acquisition
145 tracked the Ca(2+) dynamics of ensembles of amygdalar neurons during fear learning and extinction ov
146 ent study investigated the role of intrinsic amygdalar neurons in mediating stress effects on the hip
148 differentiation and functional maturation of amygdalar neurons involved in cholinergic-regulated emot
149 , the photoactivation of paAIP2 expressed in amygdalar neurons of mice during an inhibitory avoidance
152 l and REM sleep suggests that alterations in amygdalar neurotransmission may be involved in the chang
153 ults are consistent with the hypothesis that amygdalar NMDA receptors participate in normal synaptic
156 o DMI are strain dependent and that elevated amygdalar Nor-1 expression can contribute to depressive
157 ve behavior of WKYs in the FST and decreased amygdalar Nor-1 mRNA levels without affecting GR mRNA le
158 tween-group differences in primary motor and amygdalar nuclei (laterobasal, centromedial) were examin
160 (BLA), extensively connected with both local amygdalar nuclei as well as long-range circuits, is invo
161 cally expressed in medial subpallium-derived amygdalar nuclei from early developmental stages to adul
165 and in the anterior basolateral and lateral amygdalar nuclei in the brains of the conditioned-fear g
166 nd centromedial amygdala (CMA) are two major amygdalar nuclei that contribute to distinct functions v
167 e rooted in altered development of disparate amygdalar nuclei that subserve different social function
168 iverse groups of interneurons populate these amygdalar nuclei, and as predicted our data support the
169 ate cortex, reduced neuronal density in some amygdalar nuclei, and decreased calbindin-positive neuro
170 ex innervated mostly the basolateral and CeM amygdalar nuclei, poised to activate CeM for autonomic a
172 solateral, posterior basomedial, and lateral amygdalar nuclei; to the paraventricular and medial medi
174 roscopic study revealed that the basolateral amygdalar nucleus (BLa) contains a network of parvalbumi
175 eurotransmission in the anterior basolateral amygdalar nucleus (BLa) mediated by the M1 receptor (M1R
176 the anterior subdivision of the basolateral amygdalar nucleus (BLa) of the rat using electron micros
179 l caudoputamen (CP) and anterior basolateral amygdalar nucleus - areas presumably modulating somatomo
180 st, it densely innervates the medial central amygdalar nucleus and the subcommissural zone and caudal
181 uron and glia numbers in the rat basolateral amygdalar nucleus was undertaken in male and female hood
182 The PMv is heavily targeted by the medial amygdalar nucleus, and we used lesion and immediate-earl
183 , central autonomic control network (central amygdalar nucleus, BST anterolateral group, descending p
184 : central autonomic control network (central amygdalar nucleus, descending hypothalamic paraventricul
185 ; central autonomic control network (central amygdalar nucleus, descending paraventricular nucleus, a
186 ), central autonomic control system (central amygdalar nucleus, dorsal lateral hypothalamic area, ven
187 ), nucleus of the solitary tract and central amygdalar nucleus, other refeeding activated regions wer
188 l substantia innominata and adjacent central amygdalar nucleus, retrorubral area, and lateral parabra
189 ateral septal nucleus, posterior basolateral amygdalar nucleus, supramammillary nucleus, and nucleus
190 ns, caudal substantia innominata and central amygdalar nucleus, thalamic paraventricular nucleus, hyp
191 i project topographically back to the medial amygdalar nucleus, to the adjacent lateral septal nucleu
192 ral autonomic structures such as the central amygdalar nucleus, which is implicated as a stress-relat
196 lamic area; parasubthalamic nucleus; central amygdalar nucleus; area postrema; and nucleus of the sol
197 c nuclei; lateral hypothalamic area; central amygdalar nucleus; parasubthalamic nucleus; ventral post
199 nput: More recent studies of hippocampal and amygdalar or prefrontal cortical afferents suggest that
201 Obese humans also show greater striatal, amygdalar, orbitofrontal cortex, and somatosensory regio
202 e anterior cingulate cortex innervates other amygdalar parts, activating circuits to help avoid dange
204 se findings identify the subcortical pulvino-amygdalar pathway as a relevant precursor of a mature aP
210 s in addition to pOFC, it is unknown whether amygdalar pathways in MDmc innervate pOFC-bound neurons.
211 d transitional cortex that together with the amygdalar/periamygdalar region may subserve functions of
215 of emotional modulation and suggest that non-amygdalar processes contribute to the emotional modulati
216 G nucleus and suggest that distinct forms of amygdalar processes induce TIA in the MG nucleus and cin
217 These results define the time period wherein amygdalar processes initiate TIA in the MG nucleus and s
219 ese data highlight an essential role for the amygdalar projection to the ventral striatum in aversive
220 istinct functions: hypothalamic and extended amygdalar projections elicit assorted unconditioned thre
221 in other layers, suggesting that the robust amygdalar projections may also activate neurons in layer
222 In the rat, we found that activation of amygdalar protein kinase A (PKA) was sufficient to enhan
224 indicate that the synaptology of basolateral amygdalar pyramidal cells is remarkably similar to that
225 hat the HR infant phenotype predicts greater amygdalar reactivity to novel faces almost two decades l
226 was found in young subjects in the piriform/amygdalar region and in the orbitofrontal cortex and in
232 hether the previously reported dysfunctional amygdalar response patterns in ASD support an active avo
234 tive memories was associated with changes in amygdalar responses to happy and sad faces and improved
236 nts with FND would exhibit altered motor and amygdalar resting-state propagation to this network.
238 muscimol had become ineffective indicated an amygdalar role in the establishment of acquisition-relev
241 ompleted two rtfMRI-nf sessions (18 received amygdalar rtfMRI-nf, 16 received control parietal rtfMRI
242 Based on these findings, we suggest that the amygdalar signaling of fear influences the stability of
243 42; P = .009) hippocampal subfields and left amygdalar (simple slope, -34.62; standard error, 12.74;
244 ound that primate sensory cortices innervate amygdalar sites that project to the MDmc, which projects
246 olarization-evoked release of [(3)H]-NE from amygdalar slices of mice, which were trained to recogniz
248 led axon terminals, most likely arising from amygdalar sources, are positioned dually to affect LC fu
253 ical thickness, amygdala volume, and cortico-amygdalar structural networks were examined using first-
254 d neuroplasticity, contributes to changes in amygdalar structure and function following chronic stres
256 by itself has delayed detrimental effects on amygdalar structure and function, there exists a window
257 cy for parasite cysts to be more abundant in amygdalar structures than those found in other regions o
258 pression have often examined hippocampal and amygdalar structures, since they are two key structures
259 tly observed retrograde labeling in a single amygdalar subdivision, the magnocellular subdivision of
260 gue of mammalian deep cortical layers and/or amygdalar subdivisions, but one-to-one correspondences a
261 functional contributions for these different amygdalar subregions in reward-processing and motivation
262 rms of PIT have been studied at the level of amygdalar subregions in rodents, it is still unknown whe
263 t results show a double dissociation between amygdalar subsystems that control food consumption by ap
265 investigated early stress-induced changes in amygdalar synaptic signaling in order to prevent its del
269 eatening faces activated circuitry including amygdalar, thalamic, and brainstem regions, known in hum
270 dition there was a positive correlation with amygdalar Type I orexin receptor (Orx1) mRNA and depress
271 tromedial prefrontal and increasing extended amygdalar-ventral striatal activity correlated highly wi
272 score and left middle temporal thickness and amygdalar volume (Pone-tailed=0.026, 0.019 and 0.003, re
274 previous findings of reduced hippocampal and amygdalar volume among heavy cannabis users, and suggest
275 r, we report association of TCF7L2 SNPs with amygdalar volume among T2D elderly Jewish patients.
284 mozygous genotype) had significantly smaller amygdalar volume: rs7901695- CC genotype vs. CT + TT gen
288 as to examine differences in hippocampal and amygdalar volumes in patients with depression subtypes r
290 tudies have not investigated hippocampal and amygdalar volumes in PG and their relationships to BIS/B
291 ngs of relatively diminished hippocampal and amygdalar volumes in PG individuals resonate with findin
293 ging was used to measure the hippocampal and amygdalar volumes of 60 chimpanzees (Pan troglodytes).
294 us, and CA3 hippocampal subfields as well as amygdalar volumes were assessed using magnetic resonance
295 icipants were aged 25 years, hippocampal and amygdalar volumes were measured using magnetic resonance
297 es did not detect significant differences in amygdalar volumes, surface analyses indicated the presen
300 8 upregulation, indicating that cortical and amygdalar zif-268 expression during REM sleep is under h