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1 ne groups, each of which originated from one ancestral gene.
2 d patterns of activity to that of the single ancestral gene.
3 uggesting a recent duplication of the entire ancestral gene.
4 an cbl genes arose by two duplications of an ancestral gene.
5 ng that these genes originated from a common ancestral gene.
6 ntagonist seem to have evolved from a common ancestral gene.
7  that these genes have evolved from a common ancestral gene.
8 at MKP-1 and MKP-2 are derived from the same ancestral gene.
9 e, suggesting they are derived from a common ancestral gene.
10  alternate splice variants of a p63/p73-like ancestral gene.
11 d patterns of activity to that of the single ancestral gene.
12 issue-specific patterns of expression of the ancestral gene.
13 ltransferases may have evolved from a common ancestral gene.
14 suggests that they are derived from the same ancestral gene.
15 nequal genomic recombination of a duplicated ancestral gene.
16 egion has retained the basic function of its ancestral gene.
17 , suggesting that they evolved from a common ancestral gene.
18 rose from the duplication of a single common ancestral gene.
19 vin, derived from an early duplication of an ancestral gene.
20 ated gene may have a similar function to its ancestral gene.
21 mily, which has evolved from a single common ancestral gene.
22 at these two genes are evolved from a common ancestral gene.
23 insect CYP6B genes are derived from a common ancestral gene.
24 t the conclusion of derivation from a common ancestral gene.
25 d neofunctionalization of a more promiscuous ancestral gene.
26 volution, resulting in multiple copies of an ancestral gene.
27 ved the pleiotropic roles derived from their ancestral gene.
28 scades, which probably evolved from the same ancestral gene.
29 of the function or expression pattern of the ancestral gene.
30 different flavonoid regulators from a common ancestral gene.
31 by functional specialization of a duplicated ancestral gene.
32 family may have evolved from the most likely ancestral gene.
33 as evolved by gene duplication from a single ancestral gene.
34 ave evolved at different rates from a common ancestral gene.
35 tary sense and antisense strands of the same ancestral gene.
36 y with FANCD2, likely evolving from a common ancestral gene.
37  a different one of the two functions of the ancestral gene.
38 plete expression pattern and function of the ancestral gene.
39  half of all rice expansins arising from two ancestral genes.
40 n as few as 67 different genetic loci and 54 ancestral genes.
41 the X retained and the Y gradually lost most ancestral genes.
42 uggests that they have evolved from distinct ancestral genes.
43 mes, and X-chromosomes mostly conserve their ancestral genes.
44 ing that they have arisen via duplication of ancestral genes.
45 ctive pressures that preserved the surviving ancestral genes.
46 copies possess functions similar to those of ancestral genes.
47  degradation due to inactivation and loss of ancestral genes.
48  evolve differently and retain most of their ancestral genes.
49 ated new hybrid genes as well as eliminating ancestral genes.
50 ago and then duplicated and diversified from ancestral genes across the metazoan and plant kingdoms t
51 ivergent function that evolved from a common ancestral gene after a duplication event.
52 sult of regulatory changes to the peripherin ancestral gene along each lineage.
53 pendently in fish, birds and mammals from an ancestral gene also shared by TLR6 and TLR10.
54 pectively, by vertical descent from a single ancestral gene and by duplication.
55 l3, mdl4, and mdl5 are derived from a common ancestral gene and constitute members of a gene family.
56 T-II are the result of the duplication of an ancestral gene and subsequent divergence.
57          When the crossover rate between the ancestral gene and the copy-number variant is low, the e
58 ing evolutionary processes: massive decay of ancestral genes and convergent acquisition and amplifica
59 en biased, with one subgenome retaining more ancestral genes and the other sustaining more gene delet
60 ements are recent pseudogenes with conserved ancestral genes; and (ii) when analyzing metagenomic DNA
61 s and remodeling of the human genome from an ancestral gene, ANKRD26.
62     It is shown that the codon biases of the ancestral genes are much stronger than all extant flower
63  more than 80 non-syntenic genes and only 13 ancestral genes are shared among these grass species.
64 each evolved from its respective human-mouse ancestral gene around 90 million years ago.
65                 The 73 V1Rs arose from seven ancestral genes around the time of mouse-rat speciation
66  paralogues arose from a single bifunctional ancestral gene as is still present in Kluyveromyces lact
67 s clear that they were derived from the same ancestral gene as the IgG-expressing CLL B cell, thus do
68 bers arose by gene duplication from a single ancestral gene at a relatively early stage in the evolut
69 l similarity and common origin from a single ancestral gene at the onset of chordate evolution.
70              We also offer Reconstruction of Ancestral Gene blocks Using Events or ROAGUE as a softwa
71 ction of genome size, involving loss of most ancestral genes, Buchnera retains capabilities for biosy
72  descended relatively recently from the same ancestral gene but have diverged to carry out very diffe
73 shed that the human and mouse loci shared an ancestral gene, but that independent duplication events
74 t that ubiquitin and E1 are derived from two ancestral genes closely related to moaD and moeB.
75 predicts the existence of a beta-alpha-gamma ancestral gene cluster in which internal duplication of
76 nversion and/or repair after the breakage of ancestral gene clusters.
77 rily as the result of two duplications of an ancestral gene containing multiple alternatively spliced
78 ort for a common evolutionary origin from an ancestral gene containing one link module encoding exon.
79  information from extant species, as well as ancestral gene content and gene order for vertebrates an
80 genetic profiles and a correct species tree, ancestral gene content can be reconstructed with sensiti
81                                 Here, we use ancestral gene content reconstruction to track the timin
82  We show that this ancient lineage underwent ancestral gene decay paralleling extant lineages, but ev
83 GO) annotations, and a 'proxy gene' for each ancestral gene, defined as the least-diverged descendant
84 s ancestral gene duplication and 2) in locus ancestral gene direct co-option.
85  nontoxin genes for snake venom: 1) in locus ancestral gene duplication and 2) in locus ancestral gen
86                                              Ancestral gene duplication and fusion events have produc
87 d are therefore likely to be as important as ancestral gene duplication events for generating composi
88 omologous WD40 repeat proteins, revealing an ancestral gene duplication leading to two clades in plan
89 en through a three-step process initiated by ancestral gene duplication of the original BspUPG1 locus
90 phylogenetically appeared at the time of the ancestral gene duplication that led to the formation of
91 that the similarities are the remnants of an ancestral gene duplication, which may not have occurred
92  sequence level and has likely arisen due to ancestral gene duplication.
93 AP3 gene is located on 3q13.1, suggesting an ancestral gene duplication/translocation event.
94  core peptides are the products of multiple, ancestral gene duplications followed by divergence, but
95 nate genes that diverged apart from a common ancestral gene during early vertebrate evolution.
96  the product of duplication and fusion of an ancestral gene during the course of biochemical evolutio
97 ed to represent gain and loss of function by ancestral genes during evolution.
98  diminished in size and has lost most of its ancestral genes during evolution.
99 a progenitor gene which has duplicated as an ancestral gene, each copy having diverged prior to speci
100 the evolution of TBX3 and TBX5 from a common ancestral gene, each has acquired specific yet complemen
101 refoil fold arose from the duplication of an ancestral gene encoding a homotrimeric single-repeat pro
102 irect contact with hemocytes and requires an ancestral gene encoding a protein of unknown function, r
103 U gene encoding two proteins evolved from an ancestral gene encoding a single protein by the acquisit
104 135 has evolved by fusion of two independent ancestral genes encoding sialyl- and galactosyltransfera
105                                      Loss of ancestral gene families has played an important role in
106             This result implies that certain ancestral gene families-and thus the biological function
107 ent duplications in sorghum are derived from ancestral gene families.
108 56 populations using new methods for tracing ancestral gene flow, focusing primarily on Island Southe
109 logenetic evidence that epitype evolves from ancestral genes following gene duplication, and the poss
110 g 12 toxin families, we inferred most of the ancestral genes for their loci.
111 ned for a particular clade correspond to the ancestral genes found in its last common ancestor.
112   By analyzing differentiation from inferred ancestral gene frequencies, we obtained results that are
113 brate genes, suggesting it is similar to the ancestral gene from which the vertebrate Notch family ge
114 icate genes became indispensable because the ancestral gene function was divided between them.
115 3B has remained constrained by selection for ancestral gene function.
116 ing regions and can simplify the analysis of ancestral gene functions obscured by pleiotropy or haplo
117 es strongly supports the interpretation that ancestral gene functions partitioned spatially and tempo
118 ctional roles, new genes must integrate into ancestral gene-gene interaction (GGI) networks.
119                 In this work, we pinpoint an ancestral gene giving rise to a new toxin and functional
120                             The hypothetical ancestral genes had broader expression patterns than mor
121                                Although both ancestral genes had the same incremental gene amplificat
122 s were found that, though closely related to ancestral genes, had diverged by a few nucleotides.
123 ains and losses show that nearly half of all ancestral genes have been recruited into tissue-specific
124 es are the TCR, Ig, and MHC genes, but their ancestral genes have not been found in more basal verteb
125     We report here the identification of the ancestral gene ( HERC2 ) and a family of duplicated, tru
126  We specifically focused on widely conserved ancestral genes, identifying strong cores of pan-bilater
127 ined as the least-diverged descendant of the ancestral gene in a given extant genome.
128  may have been a precursor to or have had an ancestral gene in common with vancomycin resistance gene
129  previously the large HERC2 transcript as an ancestral gene in this duplicon, with approximately 11 H
130  the probability that n genes descend from m ancestral genes in a time interval of length T for the f
131 cental V1R genes suggests multiple losses of ancestral genes in carnivores and artiodactyls and gains
132 ene in the operon, and possible retention of ancestral genes in heterocystous cyanobacteria.
133 most likely represent divergence from common ancestral genes in one or both strains based on analysis
134 tworks coordinates expression from PAIs with ancestral genes in response to diverse environmental cue
135 tional INR-like homologs, suggesting that an ancestral gene insertion event and diversification prece
136 ceptor may have been lifted directly from an ancestral gene instead of being evolutionary duplication
137 s evolved that divided the regulation of the ancestral gene into two specialized genes, one of which
138  formation entailed the evolution of unknown ancestral genes into those specifying bona fide immunogl
139     For example, Tribolium has retained more ancestral genes involved in cell-cell communication than
140 t emerge from a unicellular ancestor when an ancestral gene is co-opted for cell adhesion.
141               Furthermore, duplication of an ancestral gene is thought to have led to the co-presence
142 panosoma brucei VSG have recent origins, and ancestral gene lineages have been repeatedly co-opted to
143 ed by the differential loss and retention of ancestral gene lineages, thereby generating variation in
144 her affect gene copy numbers and fractionate ancestral gene linkages across multiple chromosomes.
145 ring evolution, the original function of the ancestral gene might be retained in the different specie
146 e subunits, resulting in displacement of the ancestral genes, might have played a role in several lin
147 gues frequently remain associated with their ancestral gene neighbour, resembling NfeD1a in structure
148 e been interpreted as evidence for a shared, ancestral gene network for insect, arthropod and bilater
149                       During evolution, this ancestral gene network was expanded through gene duplica
150 o VLRA, with which it likely shares a common ancestral gene of at least 250 million years in the past
151 an invariant disulfide bond suggest that the ancestral gene of present-day CuZnSODs evolved in an aer
152 ylogenetic tree reveals that the last common ancestral gene of the family had five introns, which are
153 nd subspecies, demonstrating that toxR is an ancestral gene of the family Vibrionaceae.
154   Human insulin (INS) gene diverged from the ancestral genes of invertebrate and mammalian species mi
155 on of a primordial defensin gene yielded the ancestral genes of present day HD-5 and HD-6.
156  that these genes have evolved from a common ancestral gene or through gene duplication.
157 hat has been reorganized with respect to the ancestral gene order (a similar order that is ancestral
158 eir mating-type chromosomes, we inferred the ancestral gene order and derived chromosomal arrangement
159 irales may result from immobilization of the ancestral gene order due to the lack of a mechanism for
160                We also show that an inferred ancestral gene order for Arabidopsis reveals more synten
161  relocated within the genome relative to the ancestral gene order of angiosperm chloroplast genomes.
162 om other arthropods, and further clarify the ancestral gene order of this diverse group of arthropods
163 he original maps did to a similarly inferred ancestral gene order predating an independent paleopolyp
164                      Compared to a recovered ancestral gene order, CFA9 has undergone 11 reversals of
165                               Reconstructing ancestral gene orders in the presence of duplications is
166 w heuristic method, MULTIRES, to reconstruct ancestral gene orders with duplications guided by homolo
167  provides a basic toolbox for reconstructing ancestral gene orders with duplications.
168 The Genomicus server also provides access to ancestral gene orders, to facilitate evolutionary and co
169 hylogenetic tree reconstruction and deriving ancestral gene orders.
170 tely recover the genome phylogeny as well as ancestral gene orders.
171 assicaceae may have originated from a common ancestral gene pair present before speciation.
172 nd TACC genes arose from a physically linked ancestral gene pair.
173 y spliced genes, the inferred local order of ancestral genes, phylogenetic profiling, better cross-re
174  laboratory mouse are derived from a limited ancestral gene pool and thus QTL detected in multiple cr
175 that these individuals emerged from the same ancestral gene pool as early farmers in other parts of E
176 ent hemp and drug cultivars diverged from an ancestral gene pool currently represented by feral plant
177 port the sequencing of two diploids from the ancestral gene pools of quinoa, which enables the identi
178 oteins are likely to originate from a common ancestral gene prior to the separation of birds from mam
179                                      We used ancestral gene reconstruction to generate the most recen
180                                        Using ancestral gene reconstruction, protein engineering and X
181 ne methylation does not reinforce or replace ancestral gene regulation pathways but instead endows me
182 y of foxa phenotype is due to its role in an ancestral gene regulatory network that controlled interc
183  into the role of fungal association and the ancestral gene repertoire in the early evolution of land
184             A parsimonious reconstruction of ancestral gene repertoires shows that 4137 orthologous g
185                                      Of 2564 ancestral genes, representing an eighth of the ancestral
186                                  Here we use ancestral gene resurrection and manipulative genetic exp
187                                        Using ancestral gene resurrection, we show that, long before t
188  Tribolium and Drosophila suggests that this ancestral gene served to repress anterior development as
189 tent across the group, and reconstruction of ancestral gene sets indicate a combination of extensive
190 though X and Z Chromosomes retain nearly all ancestral genes, sex-specific W and Y Chromosomes suffer
191  Pax-4/6 and Pax-2/5/8 genes evolved from an ancestral gene similar to cnidarian Pax-B, having both t
192 s functional conservation is reflected in an ancestral gene structure identifiable in both protostome
193                            The reconstructed ancestral gene structures for these two families have ei
194 neither retains the complete function of the ancestral gene (subfunctionalization) may result in a re
195 han genes: complete sequence divergence from ancestral genes, such that homologues are not readily de
196 Y chromosome, and only three per cent of its ancestral genes survived.
197 rain evolution by altering the expression of ancestral gene targets shared between human and chimpanz
198 he differentiation of the SLRP genes from an ancestral gene that was most likely composed of 2-3 exon
199 any of these genes appear to be derived from ancestral genes that do not contain introns, this evolut
200 -day human ALDH genes were derived from four ancestral genes that existed prior to the divergence of
201 likely arose through duplication of a single ancestral gene, the relationship is now so distant that
202 lel with mammalian Y chromosomes, preserving ancestral genes through selection to maintain the dosage
203 ting proteins but the evolutionary path from ancestral gene to novel protein is challenging to trace,
204 s/rap families and suggests that tbrlp is an ancestral gene to the ras/rap genes of higher eukaryotes
205 o parsimony-based comparison of the inferred ancestral genes to pinpoint the timings of GDLs onto evo
206 transitioned from rapid, exponential loss of ancestral genes to strict conservation through purifying
207 birds, and 14 mammals-doubling the number of ancestral genes under investigation and increasing our p
208        Phylogenetic analyses reveal that the ancestral gene underwent a fission event in some Brachyc
209 ant from Neandertals, but none inherited the ancestral gene variants.
210  analyses of the r/b genes revealed that the ancestral gene was amplified independently in different
211                                     For each ancestral gene, we assign a stable identifier, and provi
212 hole-genome duplication and sharing a common ancestral gene, we found that most ACRs retained one or
213                                Many of these ancestral genes were duplicated and fixed over time to y
214 phylogenetic analyses suggest that different ancestral genes were independently amplified in sea urch
215                                 At least two ancestral genes were present in early vertebrates, which
216 rphic ospE alleles are derived from a common ancestral gene which has been modified through mutation
217 st that the four NDSTs evolved from a common ancestral gene, which diverged to give rise to two subty
218 that MGA and SI evolved by duplication of an ancestral gene, which itself had already undergone tande
219 des stable database identifiers for inferred ancestral genes, which are used to associate inferred ge
220 T evolved from the fusion of two neighboring ancestral genes, which exist as separate genes (Lrrc51 a
221  in the human Y chromosome losing 97% of its ancestral genes while gene content and order remain high
222              Deletions are likely to contain ancestral genes whose functions are no longer essential
223 , the expected pattern of variability in the ancestral gene will be similar to the predictions of mod
224 e calcium selective channels, share a common ancestral gene with the genes encoding the related nonse
225 ar to lp(A1) and lp(A2), indicating a common ancestral gene with two introns.
226 s is built on the successful evolution of 11 ancestral genes, with very different fates and progenies
227 are inferred to have descended from a common ancestral gene within a species clade.

 
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