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1 ed through structure-guided modifications of androgen receptor antagonists.
2 ovides strong rationale for developing novel androgen receptor antagonists.
3 ues were prepared and evaluated as potential androgen receptor antagonists against two human prostate
5 mide (MDV3100) is a potent second-generation androgen receptor antagonist approved for the treatment
7 NP1 was absent with co-administration of the androgen receptor antagonist bicalutamide and in androge
9 urthermore, in male mice, treatment with the androgen receptor antagonist enzalutamide did not decrea
11 ed males and those receiving the competitive androgen receptor antagonist flutamide had significantly
12 fically, we bilaterally implanted the potent androgen receptor antagonist flutamide in two key brain
14 were reversed by in vivo treatment with the androgen receptor antagonist flutamide, suggesting that
15 were divided in five groups (n = 10/group): androgen receptor antagonist (flutamide); estrogen recep
16 Moreover, prenatal administration of the androgen receptor antagonist, flutamide, equalizes devel
17 T4 in vivo and in vitro were reversed by the androgen receptor antagonist, flutamide, indicating that
19 F-0998425, (-)- 6a] is a novel, nonsteroidal androgen receptor antagonist for sebum control and treat
22 ains androgen-receptor dependent, and potent androgen-receptor antagonists induce tumour regression i
24 at mediate a switch in function of selective androgen receptor antagonists/modulators (SARMs) from re
25 osterone was repressed by co-exposure to the androgen receptor antagonist nilutamide supporting a pot
26 d-type mice, co-treatment with flutamide, an androgen receptor antagonist, prevents not only the deve
28 lnerability for treatment of next-generation androgen receptor antagonist-resistant prostate cancer b
30 (gonadotropin-releasing hormone) modulators, androgen receptor antagonists, selective estrogen recept