ライフサイエンスコーパス: anhydrase

1 ), and inorganic carbon regulation (carbonic anhydrase).

2 ted to H2S by the ubiquitous enzyme carbonic anhydrase.

3 hich is rapidly converted to H2S by carbonic anhydrase.

4 arboxylase/oxygenase (RuBisCO) with carbonic anhydrase.

5 es enzyme activity of chloroplastic carbonic anhydrase.

6 that the pH gradient is created by carbonic anhydrase.

7 eins 1 and 3, Rubisco activase, and carbonic anhydrase.

8 h is quickly hydrolyzed to H(2)S by carbonic anhydrase.

9 principal CO(2)-fixing enzyme, and carbonic anhydrase.

10 t previously observed in alpha-type carbonic anhydrases.

11 -controlled stomatal development by carbonic anhydrases.

12 on among selected human isoforms of carbonic anhydrases.

13 actual hydration rates of CO(2) by carbonic anhydrases.

14 We characterized CARBONIC ANHYDRASE 1 (CAH1) as an essential component of the CCM

15 polipoprotein E, Apolipoprotein A1, Carbonic anhydrase 1, and Hemoglobin subunit alpha upon treatment

16 markers FoxF1, Pax-1, keratin-8/18, carbonic anhydrase-12, and NC markers brachyury, galectin-3 and C

17 (8.6 kDa), myoglobin (17 kDa), and carbonic anhydrase (29 kDa) upon higher energy collisional dissoc

18 677 000 achieved for transients of carbonic anhydrase (29 kDa) with a duration of only ~250 ms.

19 verages up to 80% were achieved for carbonic anhydrase (29 kDa), 50% for aldolase (39 kDa), 46% for e

20 tomato (Solanum lycopersicum) beta-CARBONIC ANHYDRASE 3 (betaCA3) is induced by the virulent pathoge

21 a creatine kinase M-type (CK-M) and carbonic anhydrase 3 (CA-3) in the blood, more than 90% of which

22 l to the thylakoid lumen, where the carbonic anhydrase 3 (CAH3) dehydrates accumulated HCO(3) (-) to

23 ranscriptionally distinct-marked by Carbonic anhydrase 4 (Car4)-and arise from bulk ECs, as suggested

24 transfer calcium into vesicles and carbonic anhydrase 4 catalyzes the formation of bicarbonate ions

25 alivary gland protein 1 (SP1), anti-carbonic anhydrase 6 (CA6) and anti-parotid secretory protein (PS

26 alivary gland protein 1 (SP1), anti-carbonic anhydrase 6 (CA6) and parotid secretory protein (PSP).

27 ecreted phospholipase A2), and CA6 (carbonic anhydrase 6).

28 poxia-regulated genes (for example, carbonic anhydrase 9 (CA9) and vascular endothelial growth factor

29 includes the activity of the enzyme Carbonic Anhydrase 9 (CA9), a known marker of tumor aggressivenes

30 L1 expression and that of NFKB2 and carbonic anhydrase 9 (CA9).

31 including the extracellular facing carbonic anhydrase 9 (CA9).

32 ed reduced expression of myocardial carbonic anhydrase 9 and collagen, surrogate markers of myocardia

33 the well-established zinc-catalyzed carbonic anhydrase activity (p-nitrophenyl acetate, pNPA) is effe

34 Carbonic anhydrase activity emerges in the same region of the gla

35 hotosynthetic attributes along with carbonic anhydrase activity whereas its higher concentrations pro

36 rapid and simple quantification of carbonic anhydrase activity which is very important to prevent th

37 Our studies cover the invariance of carbonic anhydrase activity with different site positions and sca

38 uration constants for CO2 fixation, carbonic anhydrase activity, CO2 /HCO3 (-) uptake, delta(13) Corg

39 o be tested in species with diverse carbonic anhydrase activity.

40 bisulcatum, which has naturally low carbonic anhydrase activity.

41 The alpha-carbonic anhydrases (alpha-CAs) are a large and ancient group of

42 te constants of interaction between carbonic anhydrase and acetazolamide.

43 ent on H(+) V-ATPase, together with carbonic anhydrase and five further transporters or channels that

44 ofactor, and the Zn-binding protein carbonic anhydrase and its binding with ethoxzolamide.

45 d molecules of RuBisCO, and contain carbonic anhydrase and other accessory proteins.

46 Carbonic anhydrase and phosphoenolpyruvate carboxylase in vitro a

47 into the cell and colocalization of carbonic anhydrase and RuBisCO inside proteinaceous microcompartm

48 er than any small molecule model of carbonic anhydrase and with an efficiency within 1400-fold of the

49 key C4 metabolism genes, including carbonic anhydrases and a malate transporter.

50 f inorganic carbon transporters and carbonic anhydrases (and other supporting components) that culmin

51 ction, staying below saturation for carbonic anhydrase, and avoiding wasteful oxygenation reactions.

52 several proteins (i.e., myoglobin, carbonic anhydrase, and cytochrome c) could be analyzed by SEC-ES

53 rganic carbon transport components, carbonic anhydrases, and aggregation of Rubisco in the chloroplas

54 e putative alpha-carbonic and gamma-carbonic anhydrases, and homology modeling and molecular dynamics

55 ation factors, complement proteins, carbonic anhydrases, and redox enzymes that ostensibly contribute

56 nd expansion of gene families (e.g. carbonic anhydrase, anti-oxidative related genes), many of which

57 lization that several isoenzymes of carbonic anhydrase are associated with the development of several

58 n a kappa(2)-fashion to the protein carbonic anhydrase as a ligand.

59 as the folding modulators and human carbonic anhydrase as a model protein, we demonstrate that PFAR i

60 gue against a physiological role of carbonic anhydrase as a nitrous anhydrase or nitrite reductase as

61 We demonstrate this system using carbonic anhydrase as the target and a library of 144,000 proprie

62 ch is very important to prevent the carbonic-anhydrase-associated disorders in human.

63 tudy examined the effects of bovine carbonic anhydrase (BCA) and CO2-rich gas streams on the carbonat

64 Carbonic anhydrase buffers tissue pH by catalyzing the rapid inte

65 e compared CO(2) affinity, external carbonic anhydrase (CA(ext) ), isotopic signatures (delta(13) C)

66 hods to model the complex between a carbonic anhydrase (CA) and its protein inhibitor, showing that t

67 The process employs the enzyme carbonic anhydrase (CA) as a catalyst to accelerate the rate of C

68 hypothesis predicts that cytosolic carbonic anhydrase (CA) binds to NBCe1-A, promotes HCO3- replenis

69 ctions of these inhibitors into the carbonic anhydrase (CA) catalytic site, thus highlighting the rel

70 Carbonic anhydrase (CA) catalyzes the first biochemical step of t

71 ar pressure (IOP) by inhibiting the carbonic anhydrase (CA) enzyme to reduce aqueous humor production

72 Carbonic anhydrase (CA) enzymes catalyze the chemical equilibrati

73 Carbonic anhydrase (CA) enzymes have gained considerable attentio

74 y inhibitors are reported for human carbonic anhydrase (CA) enzymes, few may be considered useful as

75 hibition of cancer-associated human carbonic anhydrase (CA) enzymes, specifically CA IX and XII, has

76 act as effective inhibitors of the carbonic anhydrase (CA) from Trypanosoma cruzi (TcCA).

77 estration based on a self-propelled carbonic anhydrase (CA) functionalized micromotor.

78 maltose binding protein (MBP), and carbonic anhydrase (CA) in the presence of hundreds of non-binder

79 t] Finally, we show that the enzyme carbonic anhydrase (CA) increases the dissolution rate across all

80 The carbonic anhydrase (CA) inhibitors acetazolamide and its structur

81 Carbonic anhydrase (CA) inhibitors such as acetazolamide inhibit

82 hip study of a series of lipophilic carbonic anhydrase (CA) inhibitors with an acetazolamide backbone

83 possibility of developing selective carbonic anhydrase (CA) inhibitors, interactions between 17 benze

84 Carbonic anhydrase (CA) is a thoroughly studied enzyme.

85 Carbonic anhydrase (CA) is an abundant protein in most photosynth

86 Carbonic anhydrase (CA) is one of nature's fastest enzymes and ca

87 f the 12 catalytically active human carbonic anhydrase (CA) isoforms until no binding was observed be

88 ry DNAs encoding four distinct beta-carbonic anhydrase (CA) isoforms were characterized from leaf tis

89 le against therapeutically relevant carbonic anhydrase (CA) zinc metalloenzymes.

90 ns: (1) generation by extracellular carbonic anhydrase (CA), (2) release from acidic synaptic vesicle

91 carboxylase/oxygenase (RuBisCO) and carbonic anhydrase (CA), in an engineered protein cage based on l

92 erised using in vitro activities of carbonic anhydrase (CA), pyruvate, phosphate dikinase (PPDK), rib

93 However, carbonic anhydrase (CA), the enzyme that hydrolyses COS, is expec

94 ed to H2 S by the ubiquitous enzyme carbonic anhydrase (CA).

95 nolpyruvate carboxylase (PEPc), and carbonic anhydrase (CA).

96 ch is quickly converted to H(2)S by carbonic anhydrase (CA).

97 three established aminosulfonamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitor pharmacophores, cou

98 es 11a-11g, 14a-14h, and 16a-16e as carbonic anhydrase (CA, EC 4.2.1.1) inhibitors are presented.

99 tered the topic of anticancer human carbonic anhydrase (CA, EC 4.2.1.1) inhibitors, as they showed to

100 condary amines and COS as potential carbonic anhydrase (CA, EC 4.2.1.1) inhibitors, using the dithioc

101 ide derivatives acting as effective carbonic anhydrase (CA, EC 4.2.1.1) inhibitors.

102 ylphenyl-omega-aminoalkyl ethers as carbonic anhydrase (CA, EC 4.2.1.1) inhibitors.

103 btained, which showed an increasing carbonic anhydrase (CA, EC 4.2.1.1) inhibitory action with the in

104 tivity against the tumor associated carbonic anhydrase (CA, EC 4.2.1.1) isoforms hCA IX and XII are r

105 hagas disease, encodes for an alpha-carbonic anhydrase (CA, EC 4.2.1.1) possessing high catalytic act

106 A beta-carbonic anhydrase (CA, EC 4.2.1.1) was cloned and characterized

107 n (h) isoforms of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1).

108 as inhibitors of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1).

109 potent inhibitors of the beta-class carbonic anhydrase (CA; EC 4.2.1.1) enzyme expressed in Leishmani

110 ll-molecule hybrids consisting of a carbonic anhydrase (CA; EC 4.2.1.1) inhibitor linked to a CORM ta

111 Human carbonic anhydrase (CA; EC 4.2.1.1) isoforms II and VII are impli

112 the immunohistochemical analysis of carbonic anhydrases (CA) IX and XII expression in thyroid cancer.

113 Carbonic anhydrases (CA), which catalyze the reversible hydration

114 ing 6- and 7-substituted coumarins (carbonic anhydrase, CA inhibitors) derivatized with clinically us

115 We find that the carbonic anhydrase CAH6 is in the flagella, not in the stroma tha

116 ggest that intra- and extracellular carbonic anhydrases can work in concert to ensure rapid shuttling

117 In this study, we show that carbonic anhydrase (Car) enzymes are up-regulated in type 2-assoc

118 Two putative carbonic anhydrases (CAs) are encoded in the genome of C. jejuni

119 n different Ci species catalyzed by carbonic anhydrases (CAs) are key components in the CCM, and an a

120 s (CCMs) involving transporters and carbonic anhydrases (CAs) are well known, but the contribution of

121 Carbonic anhydrases (CAs) are zinc metalloenzymes that catalyze t

122 Carbonic anhydrases (CAs) are zinc metalloenzymes that interconve

123 rter, suggesting that inhibition of carbonic anhydrases (CAs) confers the beneficial thiazide effect.

124 is, direct association of cytosolic carbonic anhydrases (CAs) with the electrogenic Na/HCO(3) cotrans

125 etween CO2 and HCO3(-) catalyzed by carbonic anhydrases (CAs), and active inorganic carbon (Ci) uptak

126 availability that is determined by carbonic anhydrases (CAs).

127 Carbonic anhydrases (CAs; EC 4.2.1.1) are metalloenzymes present

128 ted the validated antitumor targets carbonic anhydrases (CAs; EC 4.2.1.1) IX and XII to attain the fi

129 Carbonic anhydrase converts COS into H2S, allowing NTAs to serve

130 hlamydomonas reinhardtii, a luminal carbonic anhydrase, CrCAH3, was suggested to improve proton remov

131 module and the plant-specific gamma-carbonic-anhydrase domain (gammaCA).

132 parison we assayed recessive ca1ca4 carbonic anhydrase double mutant plants, based on their slowed st

133 isolated Arabidopsis thaliana beta-carbonic anhydrase double mutants (ca1 ca4) exhibit an inversion

134 we have repurposed the FDA-approved carbonic anhydrase drug acetazolamide to design potent antientero

135 metal affinity of Escherichia coli carbonic anhydrase (ECCA).

136 pheric CO2 elevation, including the carbonic-anhydrase-encoding genes CA1 and CA4 and the secreted pr

137 e investigated as inhibitors of the carbonic anhydrase enzyme (CA; EC 4.2.1.1).

138 Carbonic anhydrase enzymes (CAs) catalyse the reversible hydratio

139 clinical benefits of inhibitors of carbonic anhydrase enzymes and the water channel Aquaporin-1 for

140 aken together, the study shows that carbonic anhydrases form transport metabolons with acid/base tran

141 drase gene (ca19) beyond the single carbonic anhydrase gene (ca18) that was known previously.

142 We have identified a novel carbonic anhydrase gene (ca19) beyond the single carbonic anhydra

143 1, CCP2 and LCIA) and mitochondrial carbonic anhydrase genes (CAH4 and CAH5) are up regulated in ligh

144 d synteny studies suggest that both carbonic anhydrase genes form one or two independent gene lineage

145 c conditions in which inhibitors of carbonic anhydrase have a positive effect, such as glaucoma, or a

146 Benzenesulfonamide and carbonic anhydrase have been chosen as the ligand and protein, re

147 ty against the cancer-related human carbonic anhydrase (hCA) IX and XII isoforms in the nanomolar ran

148 was synthesized and bound to human carbonic anhydrase (HCA) using a nanomolar active site ligand.

149 ng reactions and evaluated as human carbonic anhydrase (hCA, EC 4.2.1.1) inhibitors against isoforms

150 harmacologically relevant human (h) carbonic anhydrase (hCA, EC 4.2.1.1) isoforms, the cytosolic enzy

151 This study uses mutants of human carbonic anhydrase (HCAII) to examine how changes in the organiza

152 itors of the tumor-associated human carbonic anhydrases (hCAs) IX and XII.

153 ongly inhibit the activity of human carbonic anhydrases (hCAs), which are ubiquitous enzymes that cat

154 four physiologically relevant human carbonic anhydrases (hCAs, EC 4.2.1.1), isoforms hCA I, II, IX, a

155 mutation of Haemophilus influenzae carbonic anhydrase (HICA), which mimics the endogenous metal affi

156 Carbonic anhydrase I (Car1) is a gene expressed uniquely in colon

157 lity and unfolding process of human carbonic anhydrase I (HCA-I).

158 digestion of differentially labeled carbonic anhydrase I and hemoglobin allowed the identification of

159 proteins, the strict association of carbonic anhydrase I and S100A8 with ECM was verified by western

160 erum albumin, hemoglobin, and human carbonic anhydrase I were successfully labeled.

161 was demonstrated by modification of carbonic anhydrase I with electrochemically generated reactive me

162 We present a new approach to carbonic anhydrase II (CA II) inhibitor design that enables close

163 affinity to the zinc metalloenzyme carbonic anhydrase II (CA II).

164 nt screening campaign against human carbonic anhydrase II (CA II).

165 a model metalloenzyme system, human carbonic anhydrase II (CA II).

166 lyze the direct interaction between carbonic anhydrase II (CAII) and MCT1, MCT2, and MCT4, respective

167 o acidic motifs homologous to known carbonic anhydrase II (CAII) binding sequences.

168 This work employs carbonic anhydrase II (CAII) binding to immobilized 4-(2-aminoeth

169 d MCT4 is enhanced by the cytosolic carbonic anhydrase II (CAII) independent of its catalytic activit

170 TFGs containing CB[6]- and carbonic anhydrase II (CAII)-binding domains were synthesized in

171 tivin-like kinase 3 (ALK3), but not carbonic anhydrase II (CAII).

172 Human carbonic anhydrase II (HCA II) uses a Zn-bound OH(-)/H2O mechanis

173 , TPMA) to the active site of human carbonic anhydrase II (hCAII) has been investigated.

174 -HOPTO) in the active site of human carbonic anhydrase II (hCAII) has been investigated.

175 onding inhibitor complexes of human carbonic anhydrase II (HCAII) indicated that HpalphaCA possesses

176 he binding of sulfonamides to human carbonic anhydrase II (hCAII) is a complex and long-debated examp

177 e-site residues in the enzyme human carbonic anhydrase II (hCAII) that constitute the evolutionarily

178 er uses the binding pocket of human carbonic anhydrase II (HCAII, EC 4.2.1.1) as a tool to examine th

179 ave anti-retinal antibodies against carbonic anhydrase II and enolase proteins with a negative geneti

180 We have reported previously that carbonic anhydrase II augments transport activity of MCT1 and MCT

181 conversion between CO2 and HCO3(-) Carbonic anhydrase II facilitates this reversible reaction inside

182 mainly from extrainsular PDX-1(+), carbonic anhydrase II(-) (mature ductal), elastase 3a (acinar)(-)

183 teins (ubiquitin, cytochrome c, and carbonic anhydrase II) were investigated.

184 sing a panel of binders specific to carbonic anhydrase II, with dissociation constants ranging betwee

185 rate-resistant acid phosphatase, or carbonic anhydrase II.

186 wn genes, whereas Srpx2, Cd200, and carbonic anhydrase III (CAIII) were identified as novel markers o

187 Carbonic anhydrase III protects osteocytes from oxidative stress.

188 nic anhydrase XII (CA12) is the key carbonic anhydrase in epithelial fluid and HCO3 (-) secretion and

189 s study, we exploited the action of carbonic anhydrase in equilibrating CO(2) with leaf water and man

190 over the activity of zinc-dependent carbonic anhydrase in solution as an isolated protein, in intact

191 of Rubisco and the thylakoid lumen carbonic anhydrase in the pyrenoid rose substantially, coincident

192 erentially regulate the activity of carbonic anhydrase in the trans and cis configurations.

193 e H(+)-ATPase and plasma-accessible carbonic anhydrase in the vascular structure supplying the retina

194 that carbonic anhydrase may act as a nitrous anhydrase in vivo to generate nitric oxide (NO) from nit

195 igate the repertoire of cytoplasmic carbonic anhydrases in the sea lamprey (Petromyzon marinus), that

196 idal anti-inflammatory drug (NSAID)-carbonic anhydrase inhibitor (CAI) agents for the management of r

197 ch" has become a milestone in human carbonic anhydrase inhibitor (hCAI) design for various therapeuti

198 ensitive to Na(+)withdrawal, to the carbonic anhydrase inhibitor acetazolamide and to H2DIDS inhibiti

199 B. pertussis-infected mice with the carbonic anhydrase inhibitor acetazolamide reduced lung inflammat

200 Treatment of MG with an oral carbonic anhydrase inhibitor hastened anatomic recovery (P = .01)

201 lly treated with bicarbonate or the carbonic anhydrase inhibitor hydrochlorothiazide had partial rest

202 nate with the addition of a topical carbonic anhydrase inhibitor in 6 eyes and nonsteroidal anti-infl

203 Cystoid macular edema refractory to carbonic anhydrase inhibitor therapy and ultimately amenable to t

204 Given methazolamide, a potent carbonic anhydrase inhibitor, can penetrate the blood-brain barri

205 successfully translated into potent carbonic anhydrase inhibitors (IC(50) = 20.1-68.7 nM), which conf

206 eater in subjects treated with oral carbonic anhydrase inhibitors (P = .016) or Nd:YAG laser hyaloido

207 e co-transporter (P </= 0.0001) and carbonic anhydrase inhibitors (P = 0.0021).

208 Nd:YAG laser hyaloidotomy and oral carbonic anhydrase inhibitors may lead to greater IOP reduction.

209 pede time to recovery from MG, oral carbonic anhydrase inhibitors may shorten the time to anatomic re

210 Azide derivatives of 2 carbonic anhydrase inhibitors, 4-(2-aminoethyl)benzenesulfonamide

211 laucoma medications (beta blockers, carbonic anhydrase inhibitors, parasympathomimetics, and prostagl

212 were more potent agents with higher carbonic anhydrase inhibitory action than the parent dye.

213 bacteria often enclose RubisCO and carbonic anhydrase into microcompartments called carboxysomes.

214 rite bioactivation, but the role of carbonic anhydrase is abrogated when physiological concentrations

215 rusion mechanisms and extracellular carbonic anhydrase, is responsible for active transport-mediated

216 observed, in line with patterns of carbonic anhydrase isoform expression in those tissues.

217 ave been developed as inhibitors of carbonic anhydrase isoform IX.

218 ncy within 1400-fold of the fastest carbonic anhydrase isoform, CAII, and 11-fold of CAIII.

219 ein binding to maltose, and for two carbonic anhydrase isoforms binding to each of four inhibitors.

220 While several carbonic anhydrase isoforms have been identified in numerous vert

221 inhibitors of the ubiquitous human carbonic anhydrase isoforms I, II, IX, XII, and XIV using acetazo

222 e human genome encodes 15 different carbonic anhydrase isoforms that have a high degree of homology.

223 ed by Slc26a4, Slc4a8, and Slc4a9), carbonic anhydrase isoforms, and V-type H(+)-ATPase subunits in p

224 tack" screen for inhibitors against carbonic anhydrase isozyme II is performed, in which known inhibi

225 be facilitated by the extracellular carbonic anhydrase IV (CAIV) via a noncatalytic mechanism.

226 Carbonic anhydrase IV (Car4) was a top dysregulated gene with 36-

227 Carbonic anhydrase IX (CA IX) is a target for hypoxic cancer ther

228 Carbonic anhydrase IX (CA IX) is a well-established biomarker for

229 Carbonic anhydrase IX (CA IX) is an extracellular transmembrane h

230 Human carbonic anhydrase IX (CA IX) is highly expressed in tumor tissue

231 Human carbonic anhydrase IX (CA IX) is overexpressed in a number of sol

232 xic tumors is possible by targeting carbonic anhydrase IX (CA IX), an enzyme overexpressed in hypoxic

233 Carbonic anhydrase IX (CA-IX), a transmembrane enzyme, mediates c

234 Carbonic anhydrase IX (CA9) is a transmembrane glycoprotein relat

235 hypoxia is activated expression of carbonic anhydrase IX (CA9), a regulator of pH and tumor growth.

236 ial cell adhesion molecule (EpCAM), carbonic anhydrase IX (CA9), epidermal growth factor receptor (EG

237 ated therapy with the chimeric anti-carbonic anhydrase IX (CAIX) antibody girentuximab (cG250).

238 rization and acid-extruding protein carbonic anhydrase IX (CAIX) expression.

239 Carbonic anhydrase IX (CAIX) is a transmembrane enzyme that regul

240 It was induced by carbonic anhydrase IX (CAIX) overexpression and inhibited by acet

241 ined unchanged, while expression of carbonic anhydrase IX (CAIX) was greatly enhanced.

242 , which also express high levels of carbonic anhydrase IX (CAIX), a HIF1-dependent protein.

243 The present study demonstrates that carbonic anhydrase IX (CAIX), one of the major acid/base regulato

244 ate the intraoperative detection of carbonic anhydrase IX (CAIX)-expressing tumor lesions with chimer

245 gh-affinity small organic ligand of carbonic anhydrase IX (CAIX).

246 Carbonic anhydrase IX (CAIX, CA9) expression is highly upregulate

247 Inhibition of human carbonic anhydrase IX (hCA IX) has shown to be therapeutically ad

248 amics from tumor biomarkers such as carbonic anhydrase IX and topoisomerase I by immunohistochemistry

249 o were sensitive to hypoxia because carbonic anhydrase IX and zinc finger E-box binding homeobox 1 (Z

250 enin) and function (aquaporin 1 and carbonic anhydrase IX).

251 eric monoclonal antibody that binds carbonic anhydrase IX, a cell surface glycoprotein ubiquitously e

252 k correlates with the expression of carbonic anhydrase IX, and this biomarker was harnessed to uncage

253 against horseradish peroxidase and carbonic anhydrase IX, and we developed a novel, Poisson-based st

254 phatase, ALP) and a ligand-protein (carbonic anhydrase IX, CA IX) binding event.

255 r but was associated with increased carbonic anhydrase IX, hepatocyte growth factor, placental growth

256 ls that express a cancer biomarker, carbonic anhydrase IX, in response to hypoxia.

257 a novel acetazolamide derivative, a carbonic anhydrase ligand with high affinity for the tumor-associ

258 lex, which contains a putative beta-carbonic anhydrase-like active site and functions as an energy-co

259 e (F-Zn(ii)) and exhibit remarkable carbonic anhydrase-like catalytic activity.

260 It has been postulated that carbonic anhydrase may act as a nitrous anhydrase in vivo to gene

261 l molecules to proteins as large as carbonic anhydrase (molecular weight ca. 29,000).

262 stingly, transcripts of chloroplast carbonic anhydrases namely CAH6, CAH3 and LCIB are up regulated i

263 alpha-Carbonic anhydrase of Helicobacter pylori (HpalphaCA) plays an im

264 Overexpression of carbonic anhydrases on cell surfaces further contributes to acidi

265 lamide does not function as either a nitrous anhydrase or a nitrite reductase in the lungs of pigs, a

266 ccessful designs include those with carbonic anhydrase or nitrite reductase activity by incorporating

267 ical role of carbonic anhydrase as a nitrous anhydrase or nitrite reductase as a mechanism for its in

268 Carbonic anhydrase plays a key role in CO2 transport, acid-base a

269 ation at 750 microatm pCO2, reduced carbonic anhydrase protein activity and shell growth occurs in M.

270 of HCO(3)(-) from shell promoted by carbonic anhydrase provides a source of C(i).

271 We identified CAH1 as an alpha-type carbonic anhydrase, providing a biochemical role in CCM function.

272 ble intermediate associated with the nitrite anhydrase reaction in both LtHb and HbA is supported bas

273 trosylation, and still controversial nitrite anhydrase reactions.

274 orphosis resulting in distinct gill carbonic anhydrases reflecting the contrasting life modes and hab

275 ted from mouse brain, we identified carbonic anhydrase-related proteins CA10 and CA11, two homologous

276 e find dorzolamide (an inhibitor of carbonic anhydrase) results in diminished nitrite bioactivation,

277 , mannose) against matched targets (carbonic anhydrase, streptavidin, concanavalin A) to identify des

278 rbon acquisition enzymes, primarily carbonic anhydrase, stress, degradation and signaling proteins we

279 rved proteins containing domains of carbonic anhydrase, Sushi, Von Willebrand factor type A, and chit

280 phosphate carboxylase oxygenase and carbonic anhydrase that enhance carbon dioxide fixation.

281 The presence of cytosolic carbonic anhydrases, the basolateral Na(+) bicarbonate cotranspor

282 hosphate carboxylase/ oxygenase and carbonic anhydrase to facilitate carbon fixation in cyanobacteria

283 Intracellular carbonic anhydrase transcript abundance increased with temperatur

284 nnose receptor-positive, expressing carbonic anhydrase type II, but relatively low levels of cathepsi

285 Carbonic anhydrase VA (CA-VA) was absent in liver in the child wi

286 Carbonic anhydrase VI (CA6) catalyses the reversible hydration of

287 nhibitors of five isoforms of human carbonic anhydrase was also explored.

288 ydrogenase enzyme levels as well as carbonic anhydrase were enhanced with URC, contributing to pH sta

289 onuclease A, trypsin inhibitor, and carbonic anhydrase, where the latter had impurities of superoxide

290 ium bicarbonate co-transporters and carbonic anhydrases, which were also expressed in LAM lung tissue

291 The reactions of apo human carbonic anhydrase with [Rh(nbd)2]BF4 or [M(CO)2(acac)] (M=Rh, Ir

292 ixation by sequestering RubisCO and carbonic anhydrase within a protein shell that impedes CO(2) esca

293 e into the cell and localization of carbonic anhydrase within the carboxysome shell with Rubisco, cya

294 uffering was augmented by exogenous carbonic anhydrase (XCAR).

295 efflux activity as a consequence of carbonic anhydrase XII (CA XII) inhibition.

296 The expression of carbonic anhydrase XII (CA12) is associated with the expression o

297 Carbonic anhydrase XII (CA12) is the key carbonic anhydrase in ep

298 specific gene in the FLC signature, carbonic anhydrase XII (CA12), at the protein level by western bl

299 describe variants in CA12 encoding carbonic anhydrase XII in two pedigrees exhibiting CF-like phenot

300 Panning on carbonic anhydrase yielded a potent ligand, sulfonamide-WIVP, wit