ライフサイエンスコーパス: animal

1 tal importance of miRNAs in a non-bilaterian animal.

2 tion density of the social environment of an animal.

3 r (force exerted over time) generated by the animal.

4 e brain covaries with the motor state of the animal.

5 tic cell death between control and Ddr1(-/-) animals.

6 cts bacterial survival in infected cells and animals.

7 rigin of their closest living relatives, the animals.

8 targeting methods in brain tissue or living animals.

9 resting applications in cells, as well as in animals.

10 amoxicillin and ampicillin/neomycin treated animals.

11 tion in the ocean for humans and many marine animals.

12 wild pig) for removing the first 99% of the animals.

13 s in VApc and CM of control and parkinsonian animals.

14 with which we can dissect interactions among animals.

15 n snails, and place it in context with other animals.

16 sitions may be inherent in a wide variety of animals.

17 ction was evident in the bladder of the same animals.

18 inergic neurons is exacerbated in Cdnf (-/-) animals.

19 n potassium, in particular, in freely moving animals.

20 ment and social behavioral deficits in these animals.

21 to have been transmitted to humans from wild animals.

22 jority of scientific procedures conducted on animals.

23 nephron) was highest in telmisartan-treated animals.

24 s in young (3 to 7 y) and adult (12 to 23 y) animals.

25 n slices from naive but not morphine-treated animals.

26 ve within the intestines of humans and other animals.

27 omas and lymph nodes from anti-IL-10-treated animals.

28 ion imaging of dopamine dynamics in behaving animals.

29 emia in both S350L and D734A INSR-expressing animals.

30 and similar as in control mice, even in aged animals.

31 wn to play a role in light detection in most animals.

32 tionally raised mice compared with germ-free animals.

33 mogenetic activation normalised it in the MS animals.

34 ng histopathology images from these infected animals.

35 urologic dysfunction was noted for any study animals.

36 ratures reported in the literature for awake animals.

37 reside deep within the intestinal tissue of animals.

38 -/- mice, which was present already in young animals (21 days) and persisted until old age (23 months

39 logy has revolutionized our ability to track animals across the globe, significantly advancing our un

40 ajor gastrointestinal parasite of humans and animals across the globe.

41 Animals actively interact with their environment to gath

42 ation due to longer periods of exposure, and animals adapted to live in these environments are predic

43 Sporadic detection of natural cases in animals alongside successful experimental infections of

44 Here, we report that animals also make complex, microbe-like polyketides.

45 extensively employed to treat infections in animal and human medicine.

46 Our findings link animal and human studies on the neural underpinning of a

47 ber variants (CNVs) are pervasive in several animal and plant genomes and contribute to shaping genet

48 aluated MirCure on a set of manually curated animal and plant miRNAs and demonstrated great accuracy.

49 Although animal and theoretical models of addiction emphasize the

50 sposon insertion datasets in both plants and animals and compare them in the context of genome-wide t

51 and beta-hydroxybutyrate than mid-postpartum animals and control heifers.

52 tential effects from the perspectives of the animals and ecosystems exposed to the sounds.

53 age exhibiting characteristics found in both animals and fungi.

54 val as a monotherapy in KR158 glioma-bearing animals and further increased median and overall surviva

55 In line with these anatomic observations, animals and humans with incomplete SCI often show variou

56 of allergens causing allergic conditions in animals and humans.

57 unclear pathogenicity in naturally infected animals and only one experimental study demonstrating su

58 Many biological surfaces of animals and plants (e.g., bird feathers, insect wings, p

59 Although this capacity partly allows animals and plants to acutely adapt to oxygen deprivatio

60 ving under weak selective pressures, such as animals and plants.

61 at play important roles in the lives of both animals and plants.

62 ht-time warming (NTW) may impact ectothermic animals and their interactions differently as DTW result

63 dependently multiple times in algae, plants, animals, and fungi.

64 o the development and selection of humanized animal antibodies and provide actionable information for

65 rvival when three consecutive generations of animals are exposed to P. vranovensis.

66 nimals involved-hundreds of millions of live animals are imported into the U.S.A. alone every year.

67 rategies in arthropods and potentially other animals as well.

68 This suggests that in animals, as in yeast and plants, myosin/actin can drive

69 The recording of triaxial acceleration by animal-attached devices has been proposed as a way forwa

70 e to estimates from the literature for other animal behaviors, which suggests that problem-solving is

71 The study of animal behaviour could benefit greatly from generally ex

72 ion analysis, CRISPR genome editing in mice, animal behavioural analysis and cell culture studies to

73 Animal behaviours that are superficially similar can exp

74 via different pathways when decreasing soil animal biomass.

75 dicates a size ratio of roughly 20:1 between animal body length and the largest plastic the animal ma

76 a remarkable, but little explored feature of animal brains.

77 s have broader environmental tolerances than animals but are more sensitive to climate change.

78 ct are critical for survival in humans as in animals, but how a desire is translated into the decisio

79 ation and increased Wnt6 expression in these animals by EE.

80 Many experimental studies suggest that animals can rapidly learn to identify odors and predict

81 Lipid homeostasis in animal cells is maintained by sterol regulatory element-

82 its peculiar morphology shows how much these animals changed during growth and has implications for e

83 much more limited within the brains of large animals compared to rodents, rendering this approach sub

84 n occurred earlier in cyclosporine A-treated animals compared with those receiving rapamycin.

85 We also observed plant analogs of animal complexes with distinct molecular assemblies, inc

86 watched video clips of spiders and domestic animals (confrontation phase) after being primed on the

87 In urban communities, where animal contact is rare, risk factors include cesarian se

88 Notably, the titer of the IgG in wild-type animals could be increased by more than 200-fold upon re

89 We found that animals could consistently discriminate ICMS frequency u

90 ia/reperfusion injury to allografts based on animal data should be considered.

91 rganoids, potentially replacing the need for animal-derived matrices, while also allowing systematic

92 anges trigger adaptive responses that ensure animals develop properly.

93 kably, almost all IFB-2- and IFC-2-deficient animals develop to fertile adults.

94 Furthermore, when animals did not respond to the incentive stimulus, the i

95 d, five extant and nine extinct large bodied animals disappeared from the region at the end of the Pl

96 t diversity recovered in the early Holocene, animal diversity did not.

97 We show that local plant and animal diversity dropped markedly during Younger Dryas c

98 Journal of Animal Ecology, 89, 276-284.

99 al of antimicrobials for treatment under the Animal Efficacy Rule, where efficacy can be demonstrated

100 Many animal embryos pull and close an epithelial sheet around

101 were ZsG and/or PCR positive, and only from animals euthanized on or before 15 days post infection.

102 albumin and lactate levels were detected in animals euthanized with severe clinical disease compared

103 sion proteins, which play essential roles in animal evolution, tissue development, and homeostasis, a

104 cART was initiated in approximately half the animals five weeks post-infection, and morphine/saline a

105 t affect the abundance and movement rates of animals following each of these rules.

106 However, extended studies of these animals for up to 1 year revealed no reproducible abnorm

107 Most animals for which space use has been studied restrict th

108 More importantly, these immunogens protected animals from lethal challenge with both the African and

109 Live virus challenge of animals given SARS or MERS vaccines resulted in vaccine

110 rkets for subsistence and the diverse use of animals globally defies uniform bans.

111 t evidence from human newborns and non-human animals has challenged the primary role assigned to cult

112 An abundance of swimming animals have converged upon a common swimming strategy u

113 omeCage system (Neurotar Ltd, Finland) where animals have their heads fixed to an aluminum frame but

114 d discuss whether they represent a human and animal health threat, highlighting the outstanding quest

115 f IAV and its subsequent threat to human and animal health.

116 oronavirus, 178 involved study of non-human (animal) host genetic factors related to coronavirus, and

117 nitiate intestinal colonization of avian and animal hosts for commensalism and infection of humans fo

118 iral genome or antigen was noted in lungs of animals in either vaccine group.

119 ate disease is the lack of susceptible small animals in large numbers.

120 s detectable in the nose of any of the eight animals in the 100-mug dose group by day 2 after challen

121 distort visual stimuli presented to aquatic animals in water, yet refraction has often been ignored

122 In many animals including Drosophila, repressor alleles are prod

123 borne agents that cause epidemic diseases in animals including humans.

124 and throughout all cells and tissues of this animal, including the immune cells of the coelomocytes.

125 that resembles glycoproteins from unrelated animal-infecting viruses, suggesting a common ancestor f

126 found that lon-1 was highly expressed during animal infection, implying an important function of this

127 The study of factors influencing animal intake can provide a better understanding of the

128 and settings because of the vast numbers of animals involved-hundreds of millions of live animals ar

129 milarly, primordial dwarfism in domesticated animals is linked to positive selection in minor spliceo

130 It is found throughout the animal kingdom, particularly in species with prolonged p

131 of discriminate sexual behaviour across the animal kingdom.

132 diverse master regulatory factors across the animal kingdom.

133 n activity was higher across blocks in which animals learned the values of novel pairs of objects, th

134 Delivery of multiple dmAbs to a single animal led to increased neutralization breadth.

135 Environmental limits of animal life are invariably revised when the animals them

136 us ecological and life history components of animals life that may include sex differences in exposur

137 potential for this virus to infect companion animals, livestock, and wildlife that could act as viral

138 Detection of animal materials in gelatin-based products is required t

139 of the variance in the length of plastic an animal may ingest and indicates a size ratio of roughly

140 imal body length and the largest plastic the animal may ingest.

141 xylesterase homologs in C. elegans and other animals may reveal additional new compound families and

142 Animal-mediated pollination is critical for sustaining a

143 reasingly recognized as important factors in animal-microbiome interactions: for example, by providin

144 he genetic architecture and neurogenetics of animal migration remain poorly understood.

145 n in a post-traumatic stress disorder (PTSD) animal model and was related to reducing PTSD symptom de

146 been the main focus of MS research using the animal model experimental autoimmune encephalomyelitis (

147 The rhesus macaque is an important animal model for AIDS and other infectious diseases.

148 The gold standard small animal model for JUNV infection is the guinea pig.

149 young pig may, therefore, be a useful large animal model for the study of eosinophilic esophagitis i

150 chc function and to develop the first viable animal model of cblC deficiency.

151 rets represent an infection and transmission animal model of COVID-19 that may facilitate development

152 ental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis.

153 n against human tuberculosis and a validated animal model of the disease, tools to facilitate vaccine

154 In a large animal model of vascular embolization, it is shown that

155 However, in the natural animal model system of Marek's disease alphaherpesvirus

156 , and tumor-immune-system interactions in an animal model system.

157 sittacus undulatus; of either sex), an avian animal model with complex hearing abilities similar to h

158 n greatly hindered because of the lack of an animal model.

159 e human genetics studies and recent in utero animal modeling work suggest that precise control of ion

160 n signalling suppresses insulin secretion in animal models (but not in humans), is potently obesogeni

161 has been associated with CKD progression in animal models and human biopsy specimens.

162 k to bring together findings from studies in animal models and humans and to bridge the gap between r

163 ing to how well they can be recapitulated by animal models and quantify similarities between human di

164 Data from both humans and animal models are consistent in demonstrating that vapin

165 Animal models are useful for exploring the health conseq

166 s mast cells and that has shown potential in animal models as a treatment for eosinophilic gastritis

167 Experimental animal models demonstrate that maternal immune activatio

168 s are consistently observed in AD transgenic animal models devoid of such pathologies, bringing into

169 Intensive research using these animal models has revealed shared molecular mechanisms t

170 l" AF is nearly nonexistent in most species, animal models have contributed significantly to our unde

171 related responses have also been observed in animal models of BDNF deficiency in vivo, and BDNF is a

172 d studies identified marked heterogeneity in animal models of donor brain death coupled to HTx, with

173 umans presents a rich opportunity to sharpen animal models of eating disorders and to identify neural

174 Current ex vivo and animal models of hidradenitis suppurativa (HS) display i

175 derived from studies of patients with MS and animal models of how specific cytokines produced by auto

176 ssion, suggesting limitations in preclinical animal models of neurotoxicity.

177 data, due primarily to a paucity of relevant animal models of penile HIV infection.

178 proves functional and structural outcomes in animal models of retinal injury and retinal degenerative

179 r vasculature in human-relevant TMJ OA large animal models or in human TMJ tissues and cells.

180 While animal models provide the experimental flexibility to an

181 We further present advances in animal models that are important for understanding the p

182 demonstrated in 1 or more well-characterized animal models that sufficiently represent human disease.

183 We present 2 new animal models that will serve to elucidate the underlyin

184 d characterized a variety of RGC subtypes in animal models, although only a handful of studies demons

185 ideally would be obtained from (1) improved animal models, including large animal models, which inco

186 RNA-based studies conducted mainly in large-animal models, including pigs, rabbits, dogs, and nonhum

187 omplete protection against bubonic plague in animal models, the mechanisms responsible for this antib

188 w that the approach can be extended to other animal models, using chicken embryos.

189 Previous observations have relied on animal models, which differ from humans in both their de

190 (1) improved animal models, including large animal models, which incorporate the effects of aging an

191 od, largely due to the reliance on non-human animal models.

192 , and prevented liver injury in experimental animal models.

193 rization associated with retinal diseases in animal models.

194 treatment of heart failure in 2 preclinical animal models.

195 incidence of diabetes, both in humans and in animal models.

196 pertussis and prevents nasal colonization in animal models.

197 errepresented in research due to the lack of animal models.

198 aking them difficult to study in traditional animal models.

199 ctive in both prophylactic and postinfection animal models.

200 efficiently deliver hydrophobic molecules to animal models.

201 significantly advancing our understanding of animal movement [1, 2].

202 to identify plausible mechanisms of nomadic animal movement by comparing the performance of multiple

203 Effects of linear features on animal movement have seen relatively little research in

204 ur findings extend the recent work examining animal movement in response to changing phenology from m

205 vastly improved mechanistic understanding of animal movements and their roles in ecological processes

206 To overwinter, animals must detect constant cold temperatures before ad

207 All animals must transform ambiguous sensory data into succe

208 scence protein-treated controls (1012 vg per animal, n = 10 per group) with PHP.B vectors.

209 Animals navigating in a plume must therefore rely upon i

210 Animals need to remember the locations of nourishing and

211 e more pronounced in young relative to older animals, negating our hypothesis.

212 ional ingredient in food, folk medicine, and animal nutritions, as well as in nanotechnology processe

213 osquitoes are considered to be the deadliest animals on Earth because the diseases they transmit clai

214 fene have been shown to improve cognition in animals or in humans, whereas benzodiazepines were linke

215 signaling in eukaryotes is not restricted to animals or to the presence of 4D-Na(v)s.

216 bution of human-infecting viruses across the animal orders studied.

217 od and feed derived from hemp and in food of animal origin for possible transfer from feed.

218 r deconjugation of folates (PE-LC-MS/MS), or animal-origin deconjugase (rat serum and chicken pancrea

219 Butyrate absorption decreased in HS animals (P < 0.05) but increased in PF animals (P < 0.05

220 in HS animals (P < 0.05) but increased in PF animals (P < 0.05) from period 1 to period 2.

221 To assay spatial working memory, all animals performed a reinforced T-maze alternation task,

222 variation in foraging behaviour is shaped by animal personality traits, such as boldness.

223 as shown in preclinical evaluation by small-animal PET studies, organ distribution, and a patient ap

224 The dose-area product in the animal phantom was 4.6 cGy . cm(2) for DXA, 3.5-11.5 cGy

225 ulation mechanisms and their relationship to animal physiology.

226 Research on eukaryotes such as animals, plants, oomycetes and fungi has shown that P450

227 Animal populations face multiple threats induced by anth

228 al evolution are comparable to those of many animal populations.

229 Four other animals presented with multiple foci of ectopic calcific

230 the ants were omnivores, relying on a mix of animal prey and plant-based resources.

231 is nutritionally superior to diets including animal products and is healthful for children and adults

232 utlined opposing views regarding the role of animal products in human diets.

233 onal epitope mapping of these mAbs and small animal prophylaxis studies revealed a complex landscape

234 in this ancient, terrestrial, and omnivorous animal provides direct evidence of the deep history of d

235 on more than 2000 gut content analyses from animals ranging over three orders of magnitude in size (

236 of rigorous standardization in experimental animal research, we recommend the use of systematic hete

237 Here, we show that adult animals respond to ascarosides produced under conditions

238 ges and gut microbial colonization in single animals, revealing spatiotemporal dynamics undetectable

239 An animal's behavioral and physiological response to stress

240 estimated from radioactivity levels in each animal's home range combined with tissue concentrations

241 t support changes in aggression based on the animal's internal state.

242 ies have investigated the involvement of the animal's microbiome, but little is known about the host'

243 istration to female and male BALB/c mice (10 animal/sex/group) along with their human blood compatibi

244 Balfour and Shuker introduce animal sexual behaviors directed to members of the same

245 Moreover, the small intestine of treated animals show reduced hypoxic injury compared to controls

246 ind that for all ten predictions, plants and animals show similar patterns.

247 Highly anxious animals showed increased depression-like behaviors, as w

248 WT neuropathic animals showed signs of spontaneous pain and were signif

249 2 cats used in the study, with four of these animals showing tau-positive tangles and neuropil thread

250 g cells (D1-Cre-flTrkB) in which a subset of animals shows repetitive rotations and head tics with ju

251 The spread of behaviours through animal social networks have often been considered as 'si

252 Across animal societies, individuals invest time and energy in

253 Detection of animal species in meat product is crucial to prevent adu

254 Only a limited number of animal species lend themselves to becoming model organis

255 Interestingly, hearts in animal species with substantial cardiac regenerative cap

256 nvasive method for measuring stress in other animal species.

257 Animal studies demonstrated that the most potent cross-r

258 Integrated information from human and animal studies is beginning to expand insights regarding

259 s review is largely comprised of preclinical animal studies.

260 way blocks systemic coagulation and improves animal survival in three models of sepsis (cecal ligatio

261 Memory stability is essential for animal survival when environment and behavioral state ch

262 ironments is crucial to understand human and animal survival.

263 e auditory system-plays an essential role in animals' survival (e.g., detect deviant sounds that sign

264 al, to the action of NAE endocannabinoids in animal systems.

265 g population dynamics across a wide range of animal taxa.

266 may serve as a human-specific alternative to animal testing for the study of BM pathophysiology.

267 in the medial prefrontal cortex, but not in animals that cannot form new myelin.

268 rly-diverging fungi that share features with animals that have been lost in most other fungi.

269 animal life are invariably revised when the animals themselves are investigated in their natural hab

270 ial solution to this problem would be for an animal to learn the values for spatially and temporally

271 is a fundamental cognitive function enabling animals to flexibly assign sounds into behaviorally rele

272 nal blockage, ingestion of foamed PS exposes animals to harmful chemicals, and of greatest concern in

273 oronaviruses as well as the host switch from animals to humans.

274 cognition and behavior necessitate training animals to perform complex tasks.

275 ring and what can be learned from plants and animals to produce photonic materials from biopolymers a

276 Most animals took advantage of the treadmill length and its m

277 Here, we use empirical animal tracking data from 459 individual sharks and bait

278 Animals treated in vivo with a mimic nanodrug had higher

279 raises questions about the susceptibility of animals under natural conditions of pet ownership.

280 Humans and animals use mental representations of the spatial struct

281 ted neural and biomechanical mechanisms that animals use to avoid impending collisions.

282 ivo (i.e., to excised tissue) or in vivo (in animals), using antagonists of opioid receptors to infer

283 Each animal was initially injected intravenously with unlabel

284 renal injury ENaC activity in hyperglycemic animals was elevated in SS but not SS(Nox4-/-) rats.

285 18-week study, stifle (knee) joints from all animals were collected, fixed, paraffin embedded, and se

286 Animals were evaluated clinically on a daily basis durin

287 In the second protocol, sensitized animals were fed HEWP for 28 days.

288 Animals were sacrificed at week 12 and the augmented tis

289 At least 40 animals were tested per experiment, with separate testin

290 ining diminished when B16-F1 cell-inoculated animals were treated with trolox, nifedipine, or the ade

291 on for reducing cocaine-seeking behaviors in animals when given during forced abstinence.

292 s never been demonstrated in a fully aquatic animal, where sensory cues used for orientation may diff

293 pread, demonstrating that freely interacting animals (whether wild or captive) rely on social learnin

294 nd specific NCEH1 labeling in live cells and animals, while permitting facile (18) F radionuclide inc

295 of traits may be found in other ectothermic animals with high performance, particularly those for wh

296 Animals with ONS + FD developed -8.9 D of relative myopi

297 harmacology to inhibit MNK-eIF4E activity in animals with spared nerve injury, a model of peripheral

298 In chronically infected animals with viremia initially controlled by combination

299 lia is a large, ancient and diverse clade of animals, with a conserved early developmental program bu

300 ch eye-tracking can be used to determine how animals work within attentional constraints and how envi