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1 rformance of the system is illustrated by an animal experiment.
2 most up-to-date studies using these tools in animal experiments.
3 solvents and were shown to be embryotoxic in animal experiments.
4 arcinoma (HCC) are difficult to reproduce in animal experiments.
5 naling has been extensively characterized in animal experiments.
6 ielded significant functional improvement in animal experiments.
7 monstrated importance in retinal function in animal experiments.
8 s using deuterated water in cell culture and animal experiments.
9 The local animal care committee approved all animal experiments.
10 ategies for enhancing the reproducibility of animal experiments.
11 legic agents have mainly remained limited to animal experiments.
12 ntricular free wall pacing found in previous animal experiments.
13 itutional animal care committee approved all animal experiments.
14 g the angiogenic cascade by cell culture and animal experiments.
15 r mobilization of stem cells to the heart in animal experiments.
16  inhibitors of cholesterol cholelithiasis in animal experiments.
17 balloon models and in vivo and ex vivo small animal experiments.
18 molecules have produced promising results in animal experiments.
19 e defined a 'vestibulosympathetic reflex' in animal experiments.
20 ses which were similar to those found in the animal experiments.
21  human subjects are consistent with those of animal experiments.
22 -factors that are poorly modelled in current animal experiments.
23 ypokalaemia in several genetic disorders and animal experiments.
24  to metabolic disease in case studies and in animal experiments.
25  and the barriers to implementing masking in animal experiments.
26 step toward regulatory acceptance to replace animal experiments.
27          These results were also verified by animal experiments.
28 ation screening, while reducing the need for animal experiments.
29 ovascular regulation is primarily limited to animal experiments.
30 xicology models in replacement strategies of animal experiments.
31  approved by the French Ethics Committee for Animal Experiments.
32 t powerful cardioprotective interventions in animal experiments.
33       Governmental approval was obtained for animal experiments.
34 , they lack the rigor inherent in controlled animal experiments.
35 by a combined rate of 68% in two independent animal experiments.
36 e approved by the local ethics committee for animal experiments.
37 ern formation have been restricted mainly to animal experiments.
38 so displayed suitable PK profile for in vivo animal experiments.
39 periments were sequentially performed on all animals: Experiment 1--The Light and Platform test measu
40 elopment (experiment 1), as well as in adult animals (experiment 2).
41 camer duplex [d(GCGTA)-T*-d(ACGC)](2.) In an animal experiment, a 16-mer F-CeNA gapmer ASO showed sim
42                                           In animal experiments, administration of 16,16-dimethyl PGE
43 ft-versus-leukemia effect was predicted from animal experiments almost 40 years ago, only recently ha
44                                              Animal experiments also reveal that the aging process it
45 ions, cessation, dose-response relationship, animal experiments, analogy, specificity, and consistenc
46                           The study included animal experiments and a retrospective analysis of ortho
47 in eliminating the translational gap between animal experiments and clinical outcomes in humans.
48                        Growing evidence from animal experiments and clinical studies has demonstrated
49  transorbital, and transpalpebral ES in both animal experiments and clinical studies.
50                                              Animal experiments and clinical trials in adult patients
51 nucleotides (ASOs) in T(m), cell culture and animal experiments and compare them to their gap-matched
52                                              Animal experiments and epidemiological studies have sugg
53                                              Animal experiments and functional imaging studies have p
54     This cohort study supports findings from animal experiments and human observational studies in se
55 ognized phenomenon and has been described in animal experiments and human pathology.
56                                              Animal experiments and human studies provide compelling
57 enesis has been demonstrated in both in vivo animal experiments and in vitro cell culture experiments
58 t to produce the sharp filtering observed in animal experiments and many computational models that us
59                                              Animal experiments and mechanistic studies will further
60 hored in a cogent synthesis of findings from animal experiments and observational studies on diverse
61 ties in translation of cardioprotection from animal experiments and proof-of-concept trials to clinic
62  carefully considering the oral dose used in animal experiments and provides useful information in se
63 ential for ethical and scientific reasons in animal experiments and should completely cover the perio
64 he methodology can improve the efficiency of animal experiments and shows great potential for applica
65                                              Animal experiments and small clinical studies support a
66 f electrophysiological knowledge acquired in animal experiments and that currently being obtained in
67 d 4.6 g, making it suitable for future small animal experiments (and ultimately, potential evaluation
68 nciple of "Refining, Reducing and Replacing" animal experiments, and across the globe, different init
69  article reviews the basic science evidence, animal experiments, and human clinical data supporting t
70 of research, including organs-on-chip, small animal experiments, and neonatology.
71 either of the 2 approaches has fared well in animal experiments, and the only clinical experience wit
72 n is intriguing, accords with the results of animal experiments, and warrants further investigation.
73 on the basis of promising tissue culture and animal experiments, and yet they have failed to stop res
74                            Calls to halt all animal experiments appear premature, as insufficient non
75  cannot be conducted in humans, results from animal experiments are extrapolated to humans.
76                                              Animal experiments are often used to determine effects o
77  and reporting from human investigations and animal experiments are urgently needed.
78             A similar effect was observed in animal experiments as cisplatin treatment increased Notc
79 s a multitude of in vitro assays and in vivo animal experiments before a compound is moved into first
80                                           In animal experiments, blinding (also known as masking) is
81              Animal work was approved by the Animal Experiment Board of Finland.
82 ies are cited, the latter including not only animal experiments but also clinical trials.
83 ects of alcohol on the brain is supported by animal experiments, but how in vivo CB1R levels are alte
84 ial genetics, transcriptomics, metabolomics, animal experiments, chemical inhibition, and rescue stud
85                                              Animal experiments clearly show that prone positioning d
86  results in strongly attenuated virulence in animal experiments, comparable in degree to classical li
87                                              Animal experiments confirm the above and also indicate t
88                                           In animal experiments, control and streptozotocin-induced d
89                    We also review studies on animal experiments dealing with pathophysiological aspec
90                                              Animal experiments demonstrate that pre-exposure to sand
91                                              Animal experiments demonstrate that the abscess-inducing
92                                 Results from animal experiments demonstrate that the radioligand [11C
93                                              Animal experiments demonstrated that existing antibodies
94                     We will use data from an animal experiment designed to investigate the effect of
95 -mer cEt ASO showed the best activity in the animal experiments despite significantly lower T(m) and
96                                       Recent animal experiments detected reactive changes in (18)F-FE
97                                           In animal experiments, direct infusion of visfatin in mice
98                                           In animal experiments, dopamine D2-like receptor stimulatio
99 imited to electrophysiological findings from animal experiments extrapolated to humans, mathematical
100     Using the exact temporal delays from the animal experiments, fast recruitment of gain co-modulati
101                                           In animal experiments, FHNA-modified antisense oligonucleot
102                     Important laboratory and animal experiments focused on predictive models for huma
103                                              Animal experiments further showed that Nef facilitates v
104                                       In the animal experiments, gastric intramucosal PCO2 and pH wer
105            We review available evidence from animal experiments, genotoxicity studies and clinico-epi
106                                              Animal experiments had institutional animal care and use
107                                              Animal experiments have demonstrated that E6 and E7 toge
108                                              Animal experiments have demonstrated that energy intake
109                                              Animal experiments have evaluated the effects of leptin
110                                     However, animal experiments have found considerable variability i
111 ant human erythropoietin (rHuEPO) protein in animal experiments have not been consistently reproduced
112 53 and pRB: The observations from laboratory animal experiments have provided a rationale for examini
113 om human intervention studies and a range of animal experiments have questioned this concept.
114                                 Results from animal experiments have shown that human IgG2/mouse chim
115                                     Previous animal experiments have shown that serotonin is involved
116                        Although in vitro and animal experiments have supported an inverse association
117          To this end, we replicated the same animal experiment in 3 independent laboratories, each em
118 onfocal microscopy in vitro and confirmatory animal experiment in vivo.
119 redictive model to reduce the high number of animal experiments in early stage development.
120 ensitized workers spent more time performing animal experiments in the animal facility (p = 0.0001) a
121 re expected to be promising alternatives for animal experiments in the future.
122 f patients with basal ganglia disease and in animal experiments in the skeletal motor system, the res
123  prompt treatment could be demonstrated with animal experiments in vivo, in which brain damages were
124           We conducted an independent set of animal experiments in which two different and well chara
125                                           In animal experiments, in utero exposure to DDE decreases a
126                                     Cell and animal experiments indicate tau functions as a prion, as
127 epidemiological studies, clinical trials and animal experiments indicate that NSAIDs are among the mo
128                                              Animal experiments indicate that the kidney may play an
129 pidemiological studies, clinical trials, and animal experiments indicates that inhibitors of prostagl
130 ccording to a license obtained by the Danish Animal Experiments Inspectorate, Ministry of Food, Agric
131 fect of zinc intake on vitamin A status from animal experiments is inconclusive, mainly because of th
132 bution of innovative models that may replace animal experiments is limited.
133          An important source of variation in animal experiments is the microbiome, but little is know
134  On the basis of the results of this initial animal experiment, it appears that dynamic 4D four-dimen
135                                           In animal experiments knocking in a glutamic acid (S1530E)
136                                           In animal experiments: lipopolysaccharides have been furthe
137                                           In animal experiments, local and remote ischemic pre- and p
138 ly documented in vivo, and cell cultures and animal experiments may not provide accurate models.
139 n of classical microbiology, sequencing, and animal experiments may provide further insights into how
140                                           In animal experiments, methylene-cLNA antisense oligonucleo
141 ), in vitro susceptibility studies (n = 14), animal experiments (n = 6, including 5 using the neutrop
142 t theories of mechanisms are mainly based on animal experiments, not on human level.
143 Human neuroimaging studies and complementary animal experiments now identify the gross elements of th
144 od pressure comes from a variety of sources: animal experiments, observational epidemiologic studies,
145      Following favorable results obtained in animal experiments, observational studies have shown ben
146                                              Animal experiments often use reductionist approaches and
147     The translation from numerous successful animal experiments on cardioprotection beyond that by re
148 ng effects of anesthetic agents used in most animal experiments on functional connectivity.
149                                              Animal experiments on Langendorff-perfused rabbit hearts
150             The new model is able to fit the animal experiments on lymphocyte recirculation.
151    In this review, we provide an overview of animal experiments on renal IRI and IPoC, demonstrating
152 las weighing 500 g were used for 2 series of animal experiments: one to obtain specimens for scanning
153 ed during the day-most findings are based on animal experiments or human studies with observational d
154 irus (RSV) infection have been obtained from animal experiments or in vitro models.
155 le branch block (LBBB) criteria are based on animal experiments or mathematical models of cardiac tis
156             Therefore, in line with previous animal experiments, our results show that low-serotonin
157  were also supported, for the first time, by animal experiments, p65 cDNA transfection and p65 small
158 interventions, randomized controlled trials, animal experiments, physiologic investigations, evolutio
159                                           In animal experiments, probiotics were found to improve tes
160                                           In animal experiments, rabbits in sham-treated groups usual
161                                              Animal experiments revealed that overexpression of p.104
162                                           In animal experiments, sepsis without any treatment (Group
163                                              Animal experiments should better parallel clinical studi
164                    In contrast, results from animal experiments show a range of responses with the 12
165                                              Animal experiments show GPgV lymphotropism and promote g
166                                              Animal experiments show that lymphocytes activated in th
167                 Dramatic results from recent animal experiments show that noise exposure can cause a
168                                  Finally, an animal experiment showed the effective protection of gra
169                                              Animal experiments showed a role of the hippocampus for
170                                        Early animal experiments showed that a cholesterol-rich diet c
171                                      Because animal experiments showed that high efficiency of intest
172                                     However, animal experiments showed that the reassortant Sw/Korea/
173                                 Our previous animal experiments showed that transplantation of isolat
174 emic penumbra was formulated on the basis of animal experiments showing functional impairment and ele
175 The clinical trials are fueled by decades of animal experiments showing that dietary restriction dela
176       This is consistent with the results of animal experiments showing that nitric oxide exerts a fa
177                            During the entire animal experiment, statistically fewer ulcers occurred i
178 chanisms of HE deduced from cell culture and animal experiments, such as oxidative stress, altered Zn
179 ological studies, biomarker measurements and animal experiments suggest a role for aberrant immune pr
180 cologic analyses, case-case comparisons, and animal experiments suggest positive associations between
181                                              Animal experiments suggest that alterations in central p
182                   In addition, findings from animal experiments suggest that CHIP is causally involve
183                                              Animal experiments suggest that circulating palmitoleic
184                                              Animal experiments suggest that hyperchloremia resulting
185                                   Transgenic animal experiments suggest that increased expression of
186 ally similar exotoxins, toxin A and toxin B, animal experiments suggest that only toxin A mediates di
187                          Recent in vitro and animal experiments suggest that peroxisome proliferation
188                                              Animal experiments suggest that prolonging the duration
189                       Data from in vitro and animal experiments suggest that there are biochemical in
190                         Network modeling and animal experiments suggest that these genetic difference
191                                    Data from animal experiments suggest that treatment of non-convuls
192                                    Human and animal experiments suggest the involvement of MORs in hu
193                Additionally, results from an animal experiment suggested that being affected with gum
194                                  Decades-old animal experiments suggested that dietary long-chain mon
195 patients, and evidence from cell culture and animal experiments suggests the nucleus as a site of pat
196                                  Preclinical animal experiments support the use of an antisense oligo
197 ter utilize published evidence obtained from animal experiments, systematic reviews of preclinical st
198 , and BIOSIS databases were searched for all animal experiments testing tumor volume response to sora
199     These data demonstrated in a pilot large animal experiment that the BAK with RAD altered plasma c
200                           It is evident from animal experiments that the percentage of energy derived
201  clinical evidence, as well as evidence from animal experiments, that Mycobacterium tuberculosis can
202                                       In the animal experiment, the size of the ocular melanoma and t
203                                           In animal experiments, the mediators evoke anti-inflammator
204 mall sample size conditions typical of large animal experiments, the MLFRA achieved an average AUROC,
205                                       In the animal experiments, the puncture was successful in all 1
206                      Based on the results of animal experiments, the stimulation of its medial part w
207 ients are similar to those observed in these animal experiments, then the efficacy of systemic treatm
208                              By analogy with animal experiments, these regions are likely to have had
209                                              Animal experiments to assess their chronic toxicological
210 biases on published estimates of efficacy in animal experiments to be described.
211 f cardiovascular disease, ranging from early animal experiments to current sophisticated models of he
212 nk accession number AF297868) can be used in animal experiments to define the factors that are import
213 cies differences make the extrapolation from animal experiments to human clinical settings difficult.
214 here is an ongoing debate about the value of animal experiments to inform medical practice, yet there
215 f the virus life cycle crucial for designing animal experiments to model HCV infection.
216 n addition, leucine has been demonstrated in animal experiments to modulate eating and energy homeost
217                                          The animal experiment trial was done with our feed supplemen
218     These results provide a basis for future animal experiments using more ecologically relevant cond
219                                          The animal experiment was conducted according to a license o
220                                Therefore, an animal experiment was designed to simulate the transfer
221                             The protocol for animal experiments was approved by the institutional ani
222  Consistent with in vitro findings, in whole-animal experiments we found that persistent elevation of
223                                     In whole animal experiments, we demonstrated that long-term feedi
224                                           In animal experiments, we have shown that metformin can be
225                                           In animal experiments, we observed significantly lower pH a
226                     Using in vitro, cell and animal experiments, we show here that SerRS intervenes b
227 using known infection status samples, or any animal experiments were all excluded.
228                                          All animal experiments were approved by an Institutional Ani
229                            MATERIALS AND All animal experiments were approved by an institutional ani
230  stem cell research oversight committee, and animal experiments were approved by the administrative p
231                    Materials and Methods All animal experiments were approved by the animal care and
232                                              Animal experiments were approved by the animal care comm
233                                              Animal experiments were approved by the governmental rev
234                                              Animal experiments were approved by the institutional an
235                                          The animal experiments were approved by the institutional an
236                            MATERIALS AND All animal experiments were approved by the institutional an
237                        Materials and Methods Animal experiments were approved by the institutional an
238                                          All animal experiments were approved by the institutional an
239                                          All animal experiments were approved by the institutional an
240                                              Animal experiments were approved by the Johns Hopkins Un
241                    Materials and Methods The animal experiments were approved by the local ethics com
242                                          All animal experiments were approved by the local ethics com
243                                              Animal experiments were approved by the Stanford Univers
244 ated YAP pathway on the pathogenesis of DCM, animal experiments were divided into 3 parts, including
245                        Materials and Methods Animal experiments were performed according to a protoco
246                                              Animal experiments were performed according to an approv
247                        Materials and Methods Animal experiments were performed according to an approv
248                                          All animal experiments were performed according to protocols
249                                    All other animal experiments were performed in animals sedated wit
250                                          All animal experiments were performed in compliance with ins
251                                              Animal experiments were performed on normal Wistar rats
252                                          All animal experiments were performed with adherence to the
253                                              Animal experiments were performed with institutional Ani
254                                              Animal experiments were performed with institutional ani
255                                Two phases of animal experiments were performed.
256                                       Twenty animal experiments were performed.
257 st all of the laboratory studies and all the animal experiments were restricted to the case of statio
258 y reflect the integrated response of a whole animal, experiments were conducted in two human cell lin
259 These observations were recapitulated in the animal experiments where the 20-mer tcDNA ASO formulated
260 n cannot be taken for granted, especially in animal experiments where we cannot deliver explicit inst
261 d time was found to be unnecessary for small-animal experiments, whereas propagation delay and disper
262 chers encounter when designing and analysing animal experiments will improve the reliability of in vi
263 with an amount of training commensurate with animal experiments, without relying on parameter fine-tu

 
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