ライフサイエンスコーパス: annular

1 tistically significant differences in mitral annular 3D parameters before and after TAVR in both grou

2 s have provided insights into the effects of annular and bulk lipids on SERCA activation, but the rol

3 his approach, we determined the locations of annular and regulatory lipids and showed that specific p

4 and of mitral regurgitation severity and of annular and valvular dimensions by real-time 3-dimension

5 Whether physiological differences in annular and valvular dynamics exist between these phenot

6 esive force of the PVC gel is exerted on the annular anode electrode, which reduces the sagittal heig

7 ition was classified into 4 clinical stages: annular anterior capsule thickening with a distinct spli

8 There was a significant reduction in annular area (57%) and effective regurgitant orifice are

9 rements, and indexed tricuspid and neoaortic annular area decreased from 14 months to 6 years.

10 On multivariable analysis, only the TV annular area in midsystole (coefficient, 0.059; 95% conf

11 taset at baseline revealed a tricuspid valve annular area of 14.1 cm(2), and effective regurgitant or

12 The annular area was more closely correlated with the right

13 essment, patients with AF-TR had a larger TV annular area with weaker annular contraction (both P<0.0

14 n right ventricular volumes, 62% increase in annular area, and 49% increase in TLA.

15 ommercially available valve (either an intra-annular balloon-expandable Edwards-SAPIEN, SAPIEN XT, or

16 Annular-based sizing is accurate in BAV with minimal ove

17 observed 22 lipids are sufficient to form an annular belt surrounding the TAP complex.

18 equally divided segments within each square annular bin defined in the original HAH.

19 ters of the SBB we hypothesize a dynamic and annular biogeochemical zonation by which the bacteria ca

20 of mature phototrophic biofilm in a rotating annular bioreactor.

21 TEM), with high-angle annular dark-field and annular bright-field (HAADF and ABF) imaging and nanosca

22 ted spirooxindole framework bearing an intra-annular C horizontal lineC double bond was generated, wh

23 Mitral annular calcification (MAC) is associated with cardiovas

24 itation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the hi

25 TMVR in annuloplasty rings or native mitral annular calcification (MAC).

26 al valve-in-ring (MViR), and valve-in-mitral annular calcification (ViMAC) outcomes has not been perf

27 revalence of 0.6% in pts. with proven mitral annular calcification and 0.06% to 0.07% in large series

28 was omitted in 36 patients because of heavy annular calcification and in 25 for limited annular dila

29 AMCC, aortic valve calcification, and mitral annular calcification as well as quantified AMCC and aor

30 nce in aortic valve calcification and mitral annular calcification between patients with and without

31 Mitral annular calcification is an increasing problem in elderl

32 Although caseous mitral annular calcification is typically an incidental finding

33 irs with annuloplasty rings or severe mitral annular calcification who are poor surgical candidates.

34 er mitral valve replacement in severe mitral annular calcification with a dedicated prosthesis is fea

35 nosis, developing secondary to severe mitral annular calcification.

36 CT brought the suggestion of caseous mitral annular calcification.

37 ection fraction; 1.85 (1.36-2.52) for mitral annular calcification; 1.64 (1.07-2.51) for mitral E/A >

38 We aimed to evaluate the impact of mitral annular calcium (MAC) score on the development of CSA af

39 Mitral annular calcium (MAC), commonly identified by cardiac im

40 MAC (mitral annular calcium score >0) was present in 35 (33.7%) pati

41 hable conductor, surrounded by a stretchable annular conductor.

42 Here we report the dating of annular constructions made of broken stalagmites found d

43 -TR had a larger TV annular area with weaker annular contraction (both P<0.001) but a smaller tetheri

44 an array of three-dimensional (3D) metallic annular cracks on polymeric microstructures possess high

45 o find the center of artificial channels and annular cylinders, even when cytoplasmic dynein-dependen

46 lectron microscopy techniques and high-angle annular dark field (HAADF) analysis confirmed two NP pop

47 aneous imaging of the electric field, phase, annular dark field and the total charge in 2D MoS(2) and

48 ), scanning transmission electron microscopy-annular dark field imaging (STEM-ADF), electron ptychogr

49 he electron beam by optical sectioning using annular dark field imaging in a scanning transmission el

50 ntensities associated with atomic-resolution annular dark field imaging line scans reveals the types

51 y and spectroscopy tools, such as high-angle annular dark field imaging-scanning transmission electro

52 ansmission electron microscope in high angle annular dark field mode (STEM-HAADF) demonstrates the en

53 ell structure was demonstrated by high angle annular dark field scanning transmission electron micros

54 High angle annular dark field scanning transmission electron micros

55 Here, we present a high angle annular dark field scanning transmission electron micros

56 High-Angle Annular Dark Field Scanning Transmission Electron Micros

57 Electron tomography, high angle annular dark field scanning transmission electron micros

58 Aberration corrected high angle annular dark field scanning transmission electron micros

59 amework by direct synthesis, as confirmed by annular dark field scanning transmission electron micros

60 tion, in situ X-ray reflectivity, high-angle annular dark field scanning transmission electron micros

61 Atomic-resolution high angle annular dark field scanning transmission electron micros

62 y resonant soft X-ray scattering, high-angle annular dark film image transmission electron microscopy

63 columns using the atomic number (Z)-contrast annular dark-field (ADF) imaging available in STEM.

64 ectron microscopy (AC STEM), with high-angle annular dark-field and annular bright-field (HAADF and A

65 transmission electron microscopy high-angle annular dark-field imaging (STEM-HAADF).

66 process in situ in real time with high-angle annular dark-field imaging in the ESTEM, we use conditio

67 Thanks to dynamic high-angle annular dark-field imaging, electron-beam-induced damage

68 aracterized by Raman, photoluminescence, and annular dark-field scanning transmission electron micros

69 Results of high-angle annular dark-field scanning transmission electron micros

70 ms of Zn and Fe on ferritin, using cryogenic annular dark-field scanning transmission electron micros

71 High-angle annular dark-field scanning transmission electron micros

72 Aberration-corrected high-angle annular dark-field scanning transmission electron micros

73 troscopy and aberration-corrected high-angle annular dark-field scanning transmission electron micros

74 7) with X-ray photoelectron spectroscopy and annular dark-field scanning transmission electron micros

75 observe individual Ce dopants in w-AlN using annular dark-field scanning transmission electron micros

76 n diffraction and high-resolution high-angle annular dark-field scanning transmission electron micros

77 cal environment was identified by high-angle annular dark-field scanning transmission electron micros

78 ion electron microscopy (HR-TEM), high-angle annular dark-field scanning transmission electron micros

79 y abnormal dynamics demonstrate DMD-specific annular degeneration compared with the enlarged but rela

80 In this study, a modified annular denuder system (ADS) was developed to quantitati

81 rials have compared bioprostheses with supra-annular design.

82 te at 30 days was 80%, with 3 single-pledget annular detachments without reintervention.

83 for STEM images using conventional disk and annular detectors.

84 lves demonstrated an incremental increase in annular diameter similar to NV.

85 Following adjustment for valve size, annular diameter, atrial fibrillation, and ejection frac

86 We measured longitudinal changes in annular diameter, leaflet displacement, thickness, anter

87 rsus 31.5; P=0.004) and end-diastolic mitral annular diameters (median: 35.5 versus 31.5; P=0.042), p

88 versus 1.8 mm; P<0.001), end-systolic mitral annular diameters (median: 41.2 versus 31.5; P=0.004) an

89 ative valve sizing results in smaller aortic annular diameters compared with sizing based on systolic

90 most often secondary in nature and caused by annular dilatation and leaflet tethering from adverse ri

91 enlargement of the left ventricle (LV) cause annular dilatation and tethering of the mitral valve lea

92 should be effective because this entity has annular dilatation without leaflet deformation.

93 ees of tricuspid regurgitation and tricuspid annular dilatation, as well as with appreciation of the

94 annular calcification and in 25 for limited annular dilatation.

95 tion of the subvalvular apparatus, with late annular dilatation.

96 but also pays strict attention to tricuspid annular dilation (size), the mode of tricuspid leaflet c

97 re typically normal, whereas isolated mitral annular dilation and inadequate leaflet adaptation are c

98 he balance between leaflet adaptation versus annular dilation and tethering forces, is an indicator o

99 outine treatment of moderate TR or tricuspid annular dilation at the time of MV repair appears to be

100 te tricuspid regurgitation (TR) or tricuspid annular dilation in patients undergoing degenerative MV

101 In patients with moderate TR or tricuspid annular dilation who were undergoing degenerative mitral

102 ct the severity of the disease: TR severity, annular dilation, and mode of leaflet coaptation (extent

103 nnuloplasty for moderate TR and/or tricuspid annular dilation.

104 tic valve replacement in patients with small annular dimensions is challenging because they are at in

105 On average, annular dimensions were larger in DMD versus FED, but he

106 nificant reduction of TR through decrease of annular dimensions, improvements in heart failure sympto

107 tion experienced significant reduction of MV annular dimensions, which was associated with clinical r

108 l focusing organized large particles into an annular distribution that limited their transport throug

109 Dynamically, annular DMD versus FED display poorer contraction and sa

110 and ORPs are self-assembled into continuous annular DNA, meanwhile, the nanoswitch is activated.

111 r of RuHex will accumulate on the continuous annular DNA, which leads to highly sensitive detection o

112 le ClyA monomers spontaneously assemble into annular dodecameric pore complexes upon contact with mem

113 Moreover, the role of left atrial and annular dynamics in provoking MR is often underappreciat

114 ular e' velocity, (4) ratio of medial mitral annular e' to lateral e', and (5) hepatic vein expirator

115 mitral inflow E velocity, (3) medial mitral annular e' velocity, (4) ratio of medial mitral annular

116 shift, preserved or increased medial mitral annular e' velocity, and prominent hepatic vein expirato

117 ween early mitral inflow velocity and mitral annular early diastolic velocity (E/e') ratio, had the h

118 ween early mitral inflow velocity and mitral annular early diastolic velocity (E/e') reflecting eleva

119 dium Tin Oxide (ITO) glass, confined with an annular electrode operating as an artificial ciliary mus

120 with or without erythema migrans (EM) or an annular, expanding skin lesion and uninfected individual

121 In summary, we distinguish annular from non-annular lipids based on their exchange

122 (ESCRT-III) machinery localizes to sites of annular fusion in the forming NE in human cells, and is

123 How annular fusion is accomplished is unknown, but it is tho

124 the endoplasmic reticulum, and a subsequent annular fusion step to ensure that the formed envelope i

125 s employed to deal with the flow in the thin annular gap of the perivascular space between an imperme

126 of MitraClip procedure on mitral valve (MV) annular geometry and its relation to functional outcomes

127 ght to assess immediate effect of TMVR on MV annular geometry with 3-dimensional (3D) transesophageal

128 Concerning mitral valve (MV) annular geometry, we found significant reduction of ante

129 In subjects with DMR, all MV annular geometry-defining values were not significantly

130 ated by calculating the torque capability of annular graphene with varying hydrogen coverage and inne

131 to isolate each voxel's overlap with a large annular grating stimulus.

132 ergize baroclinic waves that reinforce quasi-annular hemispheric structure in the tropospheric eddy-d

133 , tailorable SAW phononic crystals, based on annular holes patterned in a SAW substrate.

134 ere, we describe a new approach by combining annular illumination with rescan confocal microscopy.

135 In DMD, the annular increased size and profoundly abnormal dynamics

136 l was to resolve the conflict by giving mice annular injuries in different locations within the corne

137 , might play in role in reducing the risk of annular injury and paravalvular regurgitation in selecte

138 he study group received larger THV, although annular injury was not observed.

139 rse Thomson scattering that clearly shows an annular intensity distribution as a remarkable feature o

140 specifically bound lipids, and non-specific, annular interactions is a challenging problem.

141 The chip consists of a gold annular interdigitated microelectrode array (3x3 format

142 nctionalization of 7-azaindole by controlled annular isomerism employing a directed metalation-group

143 unction and disintegration, and enlarged and annular LAMP-1-positive organelles in AMD RPE.

144 The supra-annular leaflet position and tall stent frame of the sel

145 pathy, was also examined for the presence of annular lesions (comparative group).

146 Fourteen eyes of 12 patients exhibited annular lesions (study eyes).

147 etinal conditions but the characteristics of annular lesions described here suggest that they are spe

148 Annular lesions occur in up to a fifth of patients with

149 Annular lesions were composed of hyperautofluorescent st

150 Annular lesions were confined to the posterior poles and

151 showed RPE hyperplasia at the perimeters of annular lesions with loss of ellipsoid reflectivity and

152 ative group and none of these eyes exhibited annular lesions.

153 ch as NapA, and likely NHA2, use a subset of annular lipids as structural support to facilitate large

154 In summary, we distinguish annular from non-annular lipids based on their exchange rates in solution

155 esults enable us to propose that a subset of annular lipids is invariant in composition, with negativ

156 An annular magnetic field profile was observed 5 ps after t

157 intraocular with a centrally located opaque annular mask measuring 3.23 mm in total diameter with a

158 f membrane proteins; these lipids are either annular, masking the protein hydrophobic surface, or spe

159 cell (hPSC) colonies to collectively form an annular mesoendoderm pattern.

160 ces of the negative polarity of the Southern Annular Mode (low SAM) is significantly linked to El Nin

161 and its leading mode of variability Northern Annular Mode (NAM).

162 ying sea ice is correlated with the Southern Annular Mode (SAM) and El Nino Southern Oscillation (ENS

163 Southern Oscillation (ENSO) and the Southern Annular Mode (SAM) are strongly associated with spatiall

164 The Southern Annular Mode (SAM) is the main driver of climate variabi

165 ated with the positive trend in the Southern Annular Mode (SAM).

166 r the 1700s is linked to a positive Southern Annular Mode (SAM).

167 /spring and a negative phase of the Southern Annular Mode (SAM).

168 outhern Oscillation Index (SOI) and Southern Annular Mode (SAM).

169 pattern is likely modulated by the Southern Annular Mode (SAM).

170 Pacific Decadal Oscillation and the Southern Annular Mode (SAM).

171 was positively correlated with the Southern Annular Mode (SAM).

172 d of wind stress curl with positive Southern Annular Mode and negative Interdecadal Pacific Oscillati

173 We identify the Southern Annular Mode as the primary climate driver responsible f

174 tion around 2014-2016, and negative Southern Annular Mode in late 2016.

175 on during the positive phase of the Southern Annular Mode in the South Atlantic and (ii) an increase

176 condition of a prolonged, negative Southern Annular Mode that induced a saltier surface layer and we

177 e jet(1,2), a positive trend in the Southern Annular Mode(1,3-6) and an expansion of the Hadley cell(

178 o, the Indian Ocean dipole, and the southern annular mode).

179 between dolphin abundance and ENSO, Southern Annular Mode, austral season, rainfall, sea surface sali

180 linity associated with the positive Southern Annular Mode, in contrast to the 1970s' condition of a p

181 were strongly teleconnected to the Southern Annular Mode.

182 In stark contrast to annular modes in conventional lasing systems, the result

183 y to achieve catenation is the design of pre-annular molecules that are capable of both efficient cyc

184 muscle (n=18), fascicular (n=15), and mitral annular (n=19) origins were studied.

185 Utilising annular nozzles for aerosol injection and installing win

186 tages of aggregation, alphaSyn forms soluble annular oligomers that show greater toxicity than much l

187 , while a TTR variant (G53A) prefers forming annular oligomers with pore-like structures.

188 oon-like beta-rich oligomers associated into annular organizations.

189 The mean annular oversizing was, respectively, 1.14+/-0.04 and 1.

190 ts and diverticula are usually asymptomatic, annular pancreas and malrotation may manifest in the fir

191 present imaging findings in a case of portal annular pancreas in a 45-year-old male patient.

192 Portal annular pancreas is a rare and often neglected pancreati

193 Portal annular pancreas is a rare pancreatic developmental anom

194 Among congenital conditions, annular pancreas, duplication cyst, superior mesenteric

195 Annular PCD (%) was defined as perfused capillary area d

196 eft ventricular ejection fraction, tricuspid annular peak systolic excursion, and systolic and diasto

197 Tricuspid annular plane excursion and RV strain did not predict ou

198 olic area, fractional area change, tricuspid annular plane excursion, and RV speckle-tracking longitu

199 by semiquantitative assessment or tricuspid annular plane systolic excursion </=15 mm, HFpEF patient

200 RV function, according to a lower tricuspid annular plane systolic excursion ( P=0.003) and RV tricu

201 urgitation velocity (27%-41%), and tricuspid annular plane systolic excursion (13%) (P<0.05 for all),

202 4]; P < 0.0001) and mean ( +/- SD) tricuspid annular plane systolic excursion (2.2 +/- 0.12 cm vs. 1.

203 cular (LV) long-axis function-lateral mitral annular plane systolic excursion (MAPSE)-in a large mult

204 l, 1.01-1.11; P=0.01) and exercise tricuspid annular plane systolic excursion (odds ratio, 0.88; conf

205 At 24 hours, lower tricuspid annular plane systolic excursion (P = 0.004) and RV frac

206 regurgitation, in comparison with tricuspid annular plane systolic excursion (TAPSE) and fractional

207 n 17beta-estradiol levels (E2) and tricuspid annular plane systolic excursion (TAPSE) at 3 months.

208 eath during follow-up according to tricuspid annular plane systolic excursion (TAPSE) quartiles.

209 oportional-hazards model, exercise tricuspid annular plane systolic excursion (TAPSE; hazards ratio [

210 d relative to the severity of RVD (tricuspid annular plane systolic excursion [TAPSE]) and according

211 nt of RV chamber function included tricuspid annular plane systolic excursion and fractional area cha

212 eft ventricular diameter ratio and tricuspid annular plane systolic excursion and improvements in fun

213 worse right ventricular function (tricuspid annular plane systolic excursion and right ventricular f

214 Tricuspid annular plane systolic excursion correlated with WHO-FC,

215 monary disease (P = 0.034) and the tricuspid annular plane systolic excursion to systolic pulmonary a

216 heart disease (P = 0.046), and the tricuspid annular plane systolic excursion to systolic pulmonary a

217 RVD defined by tricuspid annular plane systolic excursion values showed similar b

218 Tricuspid annular plane systolic excursion was not different betwe

219 es were frequent: 28% had abnormal tricuspid annular plane systolic excursion, 15% had reduced RV fra

220 me/pulmonary pulse pressure ratio, tricuspid annular plane systolic excursion, 6-minute walk distance

221 x, LV filling pressure estimation, tricuspid annular plane systolic excursion, and systolic pulmonary

222 l regurgitation, rest and exercise tricuspid annular plane systolic excursion, exercise systolic pulm

223 and five dodecamers pack together to form an annular pore.

224 form oligomers that further pack to form an annular pore.

225 archically to form hexamers, dodecamers, and annular porelike structures.

226 ety and efficacy of the self-expanding intra-annular Portico transcatheter aortic valve system (Abbot

227 Thus, anionic lipids in ubiquitous annular positions can benefit the stability of membrane

228 We show that lipids in annular positions on the presenilin homologue protease a

229 Overall, anionic lipids in annular positions stabilize the alphaIIbbeta3 TM complex

230 Customized outer annular PPCMv density in the PXG group with a value of 1

231 In both females and males, annular puncture induced structural IVD degeneration, bu

232 fered by sex, with more associations between annular puncture injury and pain in the male network.

233 Annular reactors (ARs) were used to study biofilm commun

234 ile into lithium vapour, which results in an annular region of ionization.

235 nd explains why the new phase is found in an annular region.

236 fraction, global longitudinal strain, mitral annular relaxation velocity, mitral E/e' ratio, left ven

237 the feasibility of a transcatheter tricuspid annular repair.

238 lipids already present, explicitly in plugs, annular rings, or cavities.

239 A subset of patients exhibiting annular RPE lesions on fundus autofluorescence was inclu

240 n the Sapien 3 group, 4 patients experienced annular rupture whereas this complication did not occur

241 alloon-expandable valve had a higher rate of annular rupture.

242 d mechanical support, aortic dissection, and annular rupture; technical complications of the procedur

243 Colloidal annular sectors are a broad class of shapes that offer t

244 ion of many microscale prismatic 270 degrees annular sectors, and we explore their near-equilibrium b

245 Seven consecutive equidistant 200-mum-wide annular segments were drawn at increasing eccentricities

246 s LifeSciences, Irvine, CA, USA]; or a supra-annular self-expanding CoreValve, Evolut-R, or Evolut-PR

247 were similar after the implantation of supra-annular, self-expanding transcatheter, or surgical biopr

248 chocardiography showed average reductions of annular septolateral diameter of 9% (42 mm vs. 38 mm; p

249 The annular shape of quantum rings distinguishes them from o

250 The annular shaped distribution of the dual-wavelength fs la

251 We demonstrated an abnormal double-peak (annular shaped) energy deposition through dual-wavelengt

252 syldiacylglycerol lipids are enriched in the annular shell around the protein, and form distinct bind

253 EOA increases during exercise despite fixed annular size.

254 A device annular sizing ratio (DAR) was also calculated based on

255 The annular slits are designed to selectively transmit radia

256 ce suggests clearance may be the function of annular spaces around cerebral blood vessels, called per

257 e imposed geometry supports the emergence of annular states that extend up to 100 mum, yet are fully

258 egies such as aortic root enlargement, supra-annular stented prosthetic valves, stentless bioprosthes

259 We presented annular stimuli that encircled--but did not impinge upon

260 s of colocalization problems is examining an annular structure (disk-shaped such as a cell, vesicle o

261 morphologically similar, with both having an annular structure and consisting of approximately the sa

262 Encapsulated ferritins have a distinct annular structure and must associate with an encapsulin

263 The annular structure fabricated by selective-area growth em

264 emission was realized thorough the hexagonal annular structure of GaN.

265 Moreover the annular structure of the electrodes provides lower dista

266 ering confirmed the ability of PA to form an annular structure with a radius of gyration of 7.0 +/- 1

267 uld be used to analyze colocalization of any annular structure with an arbitrarily shaped network str

268 Annular structures (rings and gaps) in disks around pre-

269 on of five astronomical units that show four annular substructures in the disk of the young (less tha

270 Multiple annular substructures observed towards disks at young ag

271 metallic superoscillatory lens assisted with annular subwavelength slits is proposed, which generates

272 reased longitudinal motion (decreased mitral annular systolic peak velocities: control median, 0.11 m

273 xcursion ( P=0.003) and RV tricuspid lateral annular systolic velocity ( P=0.02), and a higher RV Tei

274 5+/-7.0 versus 65.7+/-8.0%; P<0.0001; mitral annular systolic velocity, 11.7+/-2.6 versus 10.9+/-2.3

275 This task is particularly difficult when the annular target is composed of a large ensemble of molecu

276 ic function, and E to early diastolic mitral annular tissue velocity (E/e') to estimate LV filling pr

277 back to search for a hidden target within an annular track.

278 Supra-annular transcatheter valve position may be advantageous

279 ary artery disease (78% versus 37% of mitral annular VA patients [P=0.036]).

280 e of r<R' V1 QRS morphology, and from mitral annular VAs by lower prevalence of positive precordial l

281 llary muscle VAs, fascicular VAs, and mitral annular VAs were 83%, 87%, and 89%, respectively.

282 for papillary muscle, fascicular, or mitral annular VAs were studied.

283 een papillary muscle, fascicular, and mitral annular VAs.

284 d A) by conventional Doppler, and the mitral annular velocities (e' and a') by tissue Doppler imaging

285 sures of early diastolic and systolic mitral annular velocities, and ratio of early mitral inflow vel

286 ling peak velocity to early diastolic mitral annular velocity >14, and pulmonary vascular resistance

287 arly diastolic (E') and systolic (S') mitral annular velocity (12.8 +/- 1.0 vs 14.9 +/- 3.0 cm/sec an

288 transmitral Doppler velocity/early diastolic annular velocity (E/e') at 12 months.

289 l inflow velocity and early diastolic mitral annular velocity (E/e') was associated with poorer cogni

290 unit decrease in peak systolic septal mitral annular velocity (Septal S') indicating poorer left func

291 flow velocity to peak early diastolic mitral annular velocity [E/e'] <13 both at rest and exercise; n

292 ea under the curve of early diastolic mitral annular velocity and left ventricular longitudinal strai

293 al inflow velocity to early diastolic mitral annular velocity did not differ between the groups.

294 ak early filling velocity-to-early diastolic annular velocity ratio decreased (absolute decrease: 0.3

295 mitral flow velocity to peak early-diastolic annular velocity ratio, E/E': sham, 13.6+/-2.1, banding,

296 tory septal shift and early diastolic mitral annular velocity resulted in improved continuous net rec

297 itral inflow velocity/early diastolic mitral annular velocity; p = 0.023) as well as parameters refle

298 Of the 9 patients with sustained annular ventricular tachycardia, 3 were localized to the

299 and total layer [TL]) and 2 annuli (central annular zone 0-2 mm and peripheral zone 2-10 mm), centra

300 er of densitometry values was for the 2-6 mm annular zone of the cornea.