ライフサイエンスコーパス: annulation

1 condensation, leading to pyridin-2-one ring annulation.

2 certed asynchronous mechanism for the formal annulation.

3 tion after C-H activation and regioselective annulation.

4 the hydroxy group resulting from the initial annulation.

5 ures, respectively, prepared through lateral annulation.

6 er of events in this radical-polar crossover annulation.

7 atives as the result of a dehydrative indole annulation.

8 have ortho functional groups to complete the annulation.

9 ate (PIDA)-mediated intramolecular oxidative annulation.

10 ization and indole C2-H bond activation/Heck annulation.

11 n enantioselective variant of a useful [4+1] annulation.

12 butyl stannane followed by Pd-catalyzed Heck annulation.

13 ners, in various rhodium-catalyzed oxidative annulations.

14 arenes was developed via double radical peri-annulations.

15 erms of robust rhodaelectro-catalyzed alkyne annulations.

16 ies through a cascade of [3 + 3] and [4 + 2] annulations.

17 To prepare the DEF-ring segment for annulation, a mild dearomatization of the F-ring phenol

18 The two-directional bis-double annulation adds two new polyaromatic extensions with a t

19 This formal [3+2] annulation allowed the synthesis of diverse naphtho[2,1-

20 The controlled gold-catalyzed annulations allowed the formation of fused beta-lactams

21 d isoxazoles via palladium-catalyzed cascade annulation/allylation of alkynyl oxime ethers with allyl

22 A Rh-catalyzed tandem annulation and (5 + 1) cycloaddition was realized.

23 l-directed metallacycle-mediated [2 + 2 + 2] annulation and an intramolecular radical cyclization cas

24 , a mild aldol condensation precedes pyrrole annulation and bicyclic ring fusion.

25 A two-directional unsymmetrical double annulation and biomimetic etherification was developed t

26 The effect of annulation and carbonylation on the electronic and ligat

27 by employing an excess of alkyne, where both annulation and hydroarylation took place regio- and ster

28 ccomplished in 13 steps using a new oxindole annulation and late-stage enamine oxidation.

29 ting operations, two are classical (Robinson annulation and Mukaiyama aldol) and two are newly devise

30 ations include hydrogenation, cycloaddition, annulation, and diverse "breaking and mending" approache

31 tion, cascade C-H activation, regioselective annulation, and lactonization occur in one pot.

32 through an intramolecular allylation, [3+2] annulation, and Sakurai-like homodimerization.

33 activation; regioselective [4 + 2] oxidative annulation; and lactonization of aromatic acids, anhydri

34 This novel annulation approach also works for an aldehyde, thus pro

35 The key reactions involved in this annulation are alkyne insertion and aza-Michael addition

36 C-Glycosidation, dearomatization, and Hauser annulation are the key steps.

37 e extended to triple peri-annulations, where annulations are coupled with a radical cascade that conn

38 The procedure is amenable to (benz)annulation at both the 2,3- and 3,4-positions of the pho

39 is structure has been achieved via a [3 + 2] annulation between a terminal alkyne and a carboxamide u

40 efficient palladium-catalyzed C-H activated annulation between abundant aryl bromides and oxanorborn

41 ocyclic carbene (NHC)-catalyzed formal [4+2] annulation between alpha,beta-unsaturated aldehydes and

42 p being a chiral phosphine-catalyzed [3 + 2] annulation between an imine and an allenoate to form a p

43 nd acredinone A, which are enabled by direct annulation between aryl iodides and unsaturated carboxyl

44 An efficient MgI2-catalyzed annulation between donor-acceptor cyclopropane and N-tos

45 catalytic reaction involves a formal [3 + 3] annulation between enals and substituted malonamides ena

46 hosphine ligand promotes redox-neutral [4+2] annulation between N-H aromatic ketimines and internal a

47 A new catalytic radical-polar crossover annulation between two unsaturated carbonyl compounds is

48 um catalyzed direct regioselective oxidative annulation by double C-H activation is described to synt

49 ly efficient catalyst for dehydrative alkyne annulation by NH-free hydroxamic acids in water.

50 The products of the [3+2] annulation can be readily transformed into structures th

51 ly regioselective catalytic arene-norbornene annulation (CANAL) between dibromonaphthalenes and benzo

52 A branching double-annulation cascade (BDAC) strategy for diverse and compl

53 A one-pot sequential double annulation cascade (SDAC) strategy involving an opening

54 efully orchestrated tandem fragment coupling-annulation cascade.

55 d dihydrotropones was achieved via divergent annulation cascades.

56 s embrace a variant of metallacycle-mediated annulation chemistry where initial alkyne-carbonyl coupl

57 Directed by an oxime-masked alcohol, annulation chemoselectively occurs at the beta position,

58 esis of a cyclopentane nucleus by convergent annulation constitutes a significant challenge for synth

59 The two peri-annulations converge at a variety of polycyclic cores to

60 n via an uninterrupted C-H functionalization/annulation/decarboxylative aroylation as a formidable ch

61 port a systematic study of the Larock indole annulation designed to explore the scope and define the

62 The cooperative umpolung annulation eliminates mutual deactivation and leads to a

63 meta-terphenyls via a regioselective [3 + 3] annulation-elimination sequence involving Morita-Baylis-

64 n mechanism synthesizing polyacenes via ring annulation exemplified by the formation of pentacene (C(

65 A one-pot protocol for the enyne-RCM/Heck annulation featuring a sequential addition of the Ru and

66 f the scope and limitations of the carbamate annulation for piperidine synthesis.

67 The pivotal Hauser annulation for the anthraquinone core construction was a

68 Ring in the new: a new annulation for the efficient synthesis of substituted fu

69 ach enlists a powerful Pd(0)-mediated indole annulation for the key macrocyclization of the complex c

70 vergent, catalytic asymmetric formal [4 + 2] annulation for the synthesis of dihydroquinolones has be

71 This NHC-catalyzed annulation has been used for the total synthesis of mare

72 to the effects the regiochemically distinct annulations have on the conformation of the chromophore.

73 e-radical intermediates, and methodical ring annulation in deep space eventually changing our percept

74 onal group of the aniline derivative, and an annulation in the final step to close the quinoline ring

75 r cyclopropane and indonyl alcohol via [3+3] annulation in the presence of a Lewis acid has been demo

76 es with Schiff base formation and subsequent annulation in the presence of large N,N-dimethylamides (

77 It involves successive hetero- and benz-annulations in one pot via trans-oxo/aminopalladation on

78 involving an imine formation-intermolecular annulation-intramolecular iminium ion cyclization sequen

79 The mechanism of this 3 + 2 annulation involved a vinylogous Michael addition follow

80 DBU/Na(2)CO(3) combination-directed [3 + 3] annulation involves sulfonyl elimination via O-S or C-S

81 gas phase synthesis involves a targeted ring annulation involving free radical intermediates.

82 This intermolecular annulation involving tandem C-H activation, cyclization,

83 We report on gold(I)-catalyzed oxidative annulation involving ynamides, nitriles, and 2,3-dichlor

84 The enantioselective [3+2] annulation is catalyzed using a scandium(III)/indapybox

85 This [3 + 2]-annulation is operationally simple under metal-free reac

86 The annulation is proposed to proceed by initial formation o

87 This tandem annulation is proposed to proceed via transposition of t

88 pyridinyl acetates, Ph(3)P-catalyzed [4 + 2] annulation leads to functionalized teraryls via Mannich

89 While a double C-H activation/annulation leads to indenones, a concurrent oxidation of

90 The advantage of this unique [4 + 2]-annulation lies in the employment of readily accessible

91 sitions, carbene transfer reactions, cascade annulations, macrocyclisations or the formation of gold

92 fficiently synthesized via an aminocatalyzed annulation/O-alkylation strategy starting from simple su

93 We report the Ru-catalyzed enantioselective annulation of 1,4,2-dioxazol-5-ones to furnish gamma-lac

94 The palladium(0)-catalyzed intramolecular annulation of 12 1,3-disubstituted cyclopentenes, derive

95 organic framework (COF) through the aromatic annulation of 2,3,9,10,16,17,23,24-octa-aminophthalocyan

96 he synthesis of dibenzofurocarbazole via bis-annulation of 2,5-bis(2-pivaloyloxymethyl)pyrrole.

97 The reaction initially proceeds through the annulation of 2-(2,2-dibromovinyl)aniline, an isocyanate

98 s protocol are easily assembled via C-X bond annulation of 2-bromo-N-protected aniline with norbornad

99 Arylative annulation of 2-carbonyl-3-propargyl indoles with boroni

100 Silver-mediated annulation of 2-iodo enol esters leading to 4- and 3,4-s

101 Ruthenium-catalyzed oxidative annulation of 2H-chromene-3-carboxamides with alkynes ha

102 key step was a palladium-catalyzed oxidative annulation of 3-alkylindoles (Fujiwara-Moritani reaction

103 thenium (Ru)-catalyzed twofold unsymmetrical annulation of 3-O/N-allyl benzoic acid derivatives with

104 A diastereoselective (3 + 2) dearomative annulation of 3-substituted indoles with alpha-haloketon

105 O4-mediated one-pot stereocontrolled (4 + 2) annulation of 4-alkenols and oxygenated naphthalenes pro

106 were synthesized via base-mediated divergent annulation of 4-chloro-3-formylcoumarin and tetrahydrois

107 s of the synthetic sequence are the Robinson annulation of a beta-ketoester and methyl vinyl ketone a

108 The key steps include a Hauser-Kraus annulation of a cyanophthalide with a chiral enone-lacto

109 he reaction represents a new approach to the annulation of a pyridine ring to an indole core.

110 Ru-catalyzed regioselective cascade annulation of acrylamides with 2-alkynoates via aza-Mich

111 A copper-mediated intermolecular annulation of alkyl ketones and beta-nitrostyrenes has b

112 Highly efficient oxidative annulation of alkynes furnished diversely substituted py

113 The origin of stereoselectivity in the (3+2) annulation of allenes and enones catalyzed by an amino a

114 the phosphine-catalyzed intermolecular [3+2] annulation of allenes with alkenes; however, there have

115 ly diastereoselective Mukaiyama-type [3 + 2]-annulation of allylsilane 5 with the unsaturated aldehyd

116 A redox neutral Co(III)-catalyzed annulation of alpha,beta-unsaturated oxime ether with al

117 with the previously reported formal (3 + 3) annulation of alpha-nitro-alpha,beta-enals and 2,2-dimet

118 A method for the annulation of amines and carboxylic acids to form pharma

119 ple by Tong of a phosphine-catalyzed [4 + 1] annulation of an amine with an allene that furnished an

120 c ring has traditionally been constructed by annulation of an intact tetrapyrrole macrocycle.

121 A copper-mediated oxidative C-H/N-H annulation of aromatic amides with dialkyl malonates has

122 eveloped via Cu(II)-catalyzed intermolecular annulation of aryl ketones with a wide range of aromatic

123 A simple and efficient one-pot annulation of arylidenones, alkynes, and nitriles in the

124 can be an effective synthetic route for the annulation of benzene rings to various aromatic systems,

125 Nickel-catalyzed [4 + 2] annulation of benzylamines and nitriles via C-H/N-H bond

126 the first example of an intermolecular [4+2] annulation of cyclobutylanilines with alkynes enabled by

127 A site- and stereo-specific annulation of dihydrocholesterol and the synthesis of a

128 A new process for (4 + 2)-annulation of donor-acceptor cyclopropanes (DACs) with u

129 A new process for the [4 + 2] annulation of donor-acceptor cyclopropanes with acetylen

130 A ruthenium (Ru)-catalyzed double annulation of easily accessible N-methoxybenzamide deriv

131 red in excellent yields by an intramolecular annulation of easily prepared chalcogen-containing pyrid

132 ented N-heterocyclic carbene (NHC)-catalyzed annulation of enals to form 3,4-disubstituted cyclopenta

133 oup through the intramolecular oxidative aza-annulation of enynyl azides is reported for the first ti

134 The [3+2] annulation of gamma-butyrolactone-fused donor-acceptor c

135 Tandem C-N bond formation for the oxidative annulation of indolines with aziridines is accomplished

136 Y, via palladium-catalyzed selective [3 + 2] annulation of iodopyranoquinolines and internal akynes w

137 )Cl(2)](2)-catalyzed C(sp(2))-H alkenylation/annulation of N-(1H-pyrrolo[2,3-b]pyridin-1-yl)benzamide

138 The unsymmetrical annulation of N-methoxybenzamides with two distinct alky

139 Ruthenium-catalyzed oxidative annulation of N-quinolin-8-yl-benzamides with alkynes in

140 A visible-light-mediated annulation of N-sulfonylallylamines and olefins is repor

141 Cu(I)-catalyzed intramolecular annulation of o-ethynylquinoline-3-carbaldehydes leads t

142 dride, TFAA)-mediated intermolecular (4 + 2) annulation of oxygenated arylacetic acids with arylaldeh

143 A palladium-catalyzed tandem oxidative annulation of primary benzamides with acrylates via inte

144 The C-H activation and annulation of salicylaldehydes with diazo-compounds prov

145 The Hauser-Kraus annulation of sulfonylphthalide with 3-olefinic oxindole

146 complished by the modified Hauser-Kraus (HK) annulation of sulfonylphthalide with o-hydroxychalcones

147 uilding block by a (4 + 2)-cycloaddition for annulation of the B ring.

148 ward POCl(3) mediated intermolecular (5 + 1) annulation of the beta-ketosulfones with an o-hydroxyary

149 st-15 mediated intramolecular Friedel-Crafts annulation of the corresponding beta-ketosulfones or bet

150 an oxidative cleavage/oxidation sequence for annulation of the delta-lactone (C ring).

151 The annulation of the dipivalate proceeds through the interm

152 Annulation of the final ring was achieved through visibl

153 nstruction of the carbazole framework and an annulation of the pyran ring, which is either catalyzed

154 uential BF(3).OEt(2)-mediated intramolecular annulation of the resulting 3-sulfonyl-2-benzylchroman-4

155 The annulation of the sultam fragment to the triazole ring p

156 hly enantioselective Pd(PPh3)4/NHC-catalyzed annulation of vinyl benzoxazinanones and enals has been

157 I) complexes enabled efficient redox-neutral annulations of alkynes with readily available oximes.

158 ine (NHOMe) assists the unsymmetrical double annulations of arenes [that use both N- and O-heteroatom

159 We report formal [3 + 3] annulations of aromatic azides with aromatic imines and

160 y of phosphine-catalyzed [3 + 2] and [3 + 3] annulations of azomethine imines and allenoates have bee

161 Homoenolate annulations of beta-aryl enals catalyzed by an N-heteroc

162 lic substitution enables [3 + 2] and [4 + 2] annulations of N-acylhydrazones to afford substituted py

163 , unprecedented diverse C-H activation/[4+2] annulations of simple benzoic acids are reported.

164 The challenging annulations of two different alkynes in a regioselective

165 hetic efforts and to summarize the effect of annulation on the properties of expanded and isomeric po

166 a Rh(III)-catalyzed diastereoselective [2+1] annulation onto allylic alcohols initiated by alkenyl C-

167 3-Point annulations, or phenalenannulations, transform a benzene

168 theory calculations suggest that the [3 + 2]-annulation pathway is strongly preferred over the possib

169 e-radical intermediates, and systematic ring annulation potentially yielding molecular wires along wi

170 This one-pot annulation proceeds through an interrupted Pummerer reac

171 The annulation proceeds under exceptionally mild conditions

172 This base-promoted formal [4+2] annulation proceeds via cyclohexanone formation and invo

173 fluorophile and desiccant to facilitate the annulation process across three different azaborininone

174 A highly efficient one-pot [4 + 1]-annulation process for the asymmetric synthesis of dense

175 ionalized carbazole derivatives via a double annulation process that generates two C-C and two C-N bo

176 The synthesis involves a two-step annulation process that rapidly assembles the tetracycli

177 A phosphine-catalyzed novel [4+2] annulation process was devised employing allene ketones

178 offers an insight into the mechanism of the annulation process.

179 IQs) in high chemoselectivity over competing annulation processes, exclusive cis-diastereoselectivity

180 ivation, heteroatom alkylation/arylation and annulation processes, in which aspects such as chemosele

181 se-, and palladium-catalyzed cyclization and annulation processes.

182 voring the 5-exo-dig cyclizations in all the annulation processes.

183 nistic explanation for the formation of each annulation product could be provided, which has improved

184 hotocatalyst Ru(I)(bpz)3(+), and the [3 + 2] annulation product radical cation 3(+*) are all successf

185 e high chemoselectivity for the formal [4+2] annulation product.

186 The annulation products can be readily transformed into benz

187 tandem reactions to generate spirocyclic or annulation products under cross-coupling conditions, rem

188 A one step formal [3+2]-annulation protocol for the synthesis of 2,3-disubstitut

189 This route was enabled by a diketene annulation reaction and an oxidative ring expansion stra

190 f PEG-400 as a green solvent for the (3 + 2) annulation reaction and multiple catalytic reactions wit

191 starting materials toward the carbonylative annulation reaction and yielded 3-arylbenzo-1,2,3-triazi

192 Examples of this metallacycle-mediated annulation reaction are provided to demonstrate that a r

193 Herein we describe a salicylaldehyde-annulation reaction as a plug and play toolkit to divers

194 A cascade Friedel-Crafts/Michael annulation reaction between acryloyl chloride and 2-meth

195 ties based on palladium (Pd)-catalyzed [3+2] annulation reaction between bromo-chloro-naphthalene dic

196 The Sc(OTf)3-catalyzed [3 + 2]-annulation reaction between cyclopropenones and donor-ac

197 A regio- and enantioselective formal [4 + 3] annulation reaction between enals and in situ formed azo

198 and enables the regio- and enantioselective annulation reaction between enals and vinyl benzoxazinan

199 A dirhodium(II)-catalyzed annulation reaction between two structurally different d

200 The pathway described features an annulation reaction conceived to address the uniquely co

201 addition, we have further developed a novel annulation reaction for the synthesis of hydroxylated 1,

202 A tandem Michael-S(N)Ar annulation reaction has been developed for the synthesis

203 ted metallacycle-mediated hydrindane-forming annulation reaction in natural product synthesis and the

204 Pd(0) catalyzed carbonylative annulation reaction of 1-(2-iodophenyl)-3-aryltriaz-1-en

205 alladium-catalyzed one-pot stepwise coupling-annulation reaction of 2-chloroqunoline-3-carbonitriles

206 The selective annulation reaction of alkynes with substrates containin

207 mple of a dynamic kinetic asymmetric [3 + 2] annulation reaction of aminocyclopropanes with both enol

208 Herein, we report a transition-metal-free annulation reaction of benzynes and 1,3-oxopentanedioate

209 tions involved in the intermolecular [3 + 2] annulation reaction of N-cyclopropylaniline (CPA, 1) and

210 ed from the dehydrative C-H alkenylation and annulation reaction of phenols with 1,2-diols.

211 A novel Pd(0) -catalyzed asymmetric [4+3] annulation reaction of two readily accessible starting m

212 s catalysts for the enantioselective [4 + 1] annulation reaction of vinyl benzoxazinones and sulfur y

213 ere through the design and realization of an annulation reaction that accomplishes what previously es

214 -aldehyde cyclization, and a newly developed annulation reaction that allows efficient coupling of a

215 olymerization and the reaction center for an annulation reaction that laterally extends the conjugate

216 An asymmetric [3+2] annulation reaction to form 3-pyrroline products is repo

217 fruitfully participated in the one-pot ipso-annulation reaction to provide the corresponding 3-iodo

218 An Fe(III)-promoted oxidative annulation reaction was developed for the synthesis of 1

219 A three-component annulation reaction was developed for the synthesis of p

220 The regioselectivity of the second annulation reaction was rationalized computationally on

221 In addition to defining the basic annulation reaction we have discovered a surprising stab

222 isoquinoline-2-oxide was demonstrated in the annulation reaction with 1-(2-bromophenyl)-3-phenylprop-

223 highly enantioselective NHC-catalyzed [3+2] annulation reaction with alpha,beta-alkynals and alpha-k

224 o support the chain mechanism in the [3 + 2] annulation reaction.

225 of dihydronaphthofurans via AgTFA-catalyzed annulation reaction.

226 actams via a tandem C-H activation and [4+2] annulation reaction.

227 d from the resulting regioselectivity of the annulation reactions and DFT studies indicates that a me

228 anometallic aryl-Co(III) compounds in alkyne annulation reactions are also disclosed.

229 sis on ring-closing metathesis reactions and annulation reactions based on C-H activation.

230 oloindolines by means of (3 + 2) dearomative annulation reactions between 3-substituted indoles and h

231 Here, we have realized metallacycle-mediated annulation reactions for the assembly of angularly subst

232 of alkoxide-directed Ti-mediated [2 + 2 + 2] annulation reactions have been discovered for the synthe

233 The present procedure describes annulation reactions in one or two steps starting from 5

234 results on potassium tert-butoxide promoted annulation reactions of 2-alkynylphenyl propargyl ethers

235 ted herein are the Rh(III)-catalyzed cascade annulation reactions of N-(pivaloyloxy)benzamides with 1

236 Annulation reactions via insertion of alkynes into both

237 etrahydroisoquinoline undergo regiodivergent annulation reactions with 4-nitrobutyraldehydes.

238 oxamic acid-directed Rh(III)-catalyzed (4+2) annulation reactions with alkynes was investigated compu

239 tion of (hetero)arenes and arylative radical annulation reactions with alkynes.

240 polymers using efficient palladium catalyzed annulation reactions with low catalyst loading (1 mol %)

241 oxide-directed titanium-mediated [2 + 2 + 2] annulation reactions).

242 e intermediates in the course of [2 + 2 + 2] annulation reactions.

243 broad family of targets based on an abiotic annulation/rearrangement strategy resulting in a 10-step

244 d from a 5-phenylthiobutenolide via a tandem annulation/reductive thiolation reaction.

245 tigations, all known approaches are based on annulations, relying on the union of properly prefunctio

246 dium-catalyzed regioselective [3 + 2] alkyne annulation/ring-opening followed by intramolecular aldol

247 e precursors in high yields in an alkylation/annulation sequence.

248 ur component reaction (4CR)/copper-catalyzed annulation sequence.

249 Here, we describe (4 + 3) and (3 + 2) indole annulation strategies that quickly generate complex indo

250 wise manner because of the lack of efficient annulation strategies.

251 An asymmetric organocatalytic [3 + 3] annulation strategy based on a Michael addition/intramol

252 An anionic annulation strategy employing isatoic anhydrides and a w

253 A new [3 + 3]- and [3 + 4]-annulation strategy involving azaoxyallyl cation and [1,

254 An efficient annulation strategy involving the reaction of phenolic a

255 This oxidative [3 + 2] annulation strategy is highly regiospecific to proceed a

256 ccomplished using a Ru(II)-catalyzed (3 + 2) annulation strategy to construct the central pyrrole rin

257 s (DDs) were engaged in interceptive [4 + 1] annulation strategy with diazo esters (DEs).

258 extension of this method to one-pot cascade annulation strategy.

259 An effective [3+2] annulation tactic for the construction of diverse bicycl

260 This novel [3 + 3] annulation takes advantage of the 1,3-bielectrophilic ch

261 ntly Antonchick and Manna described a unique annulation that knits together three acetophenones to co

262 eloped an oxocarbenium-ion-initiated cascade annulation that provides us access to the ABCD ring stru

263 h as [5]- and [6]-helicene via stepwise ring annulation through bimolecular gas phase reactions in ci

264 We report here a new, atom economical annulation to 2,1-benzisoxazole scaffolds via the BF3.Et

265 tched the reactivity toward a formal [4 + 1] annulation to afford functionalized pyrazoles.

266 nvolving an opening of isatoic anhydride and annulation to benzimidazole and further nickel-catalyzed

267 The reaction features an initial [3+2] annulation to form bicyclic hemiaminals, followed by rin

268 halo aldehydes, which undergo regioselective annulation to form borylated thiazoles.

269 nd bases, are suitable for the [4+2] anionic annulation to give 3-(2-alkenyl)naphthoates in regiospec

270 ne, which engaged in acid-catalyzed Robinson annulation to give the bicyclic enone.

271 h leads to 6-endo-dig-selective chlorinative annulation to give the desired products in moderate to q

272 n the aniline and one of the ketones, before annulation to the heterocyclic ring.

273 to seven member ring and turned on 6-exo-dig annulations to afford family of six-membered benzoxazino

274 m(III)-catalyzed, all-carbon [3+3] oxidative annulations to produce spirodialins.

275 and tetrasubstituted enones are amenable to annulation under this protocol.

276 A Robinson annulation, van Leusen homologation, and a desymmetrizin

277 This protocol provides a highly effective annulation via one carbon-oxygen (C-O) and one carbon-ca

278 s protocol provides a highly effective (4+2) annulation via one carbon-oxygen and one carbon-carbon b

279 l transformation represents a formal [3 + 2] annulation via rearrangement.

280 highly effective regio- and stereoselective annulation via the formation of one carbon-carbon (C-C)

281 method describes a highly efficient (3 + 2) annulation via the formation of two carbon-carbon (C-C)

282 This protocol provides a highly effective annulation via two carbon-nitrogen (C-N) and one carbon-

283 side as the vic-cis-diol moiety the chromene-annulation was based on or on the opposite side.

284 In addition, the scope of the [3 + 2]-annulation was evaluated and enhanced utilizing diastere

285 The annulation was promoted by tin(IV) chloride, and the pro

286 This approach can be extended to triple peri-annulations, where annulations are coupled with a radica

287 in the synthesis is an I2-mediated carbamate annulation, which allows for the cyclization of hydroxy-

288 ligand functionalized product via a [3 + 2] annulation, which can be mediated by a high-valent nitre

289 t-free domino process facilitates the double annulation with a variety of scaffold building agents vi

290 d C(sp(2))-H functionalization and oxidative annulation with alkynes to give spiroindenes containing

291 catalyst, these substrates undergo oxidative annulation with alkynes to provide spiroindenes exclusiv

292 complex and its subsequent participation in annulation with an alkene.

293 NaN(3) as the azide component in the [3 + 2] annulation with arynes generated from 2-(trimethylsilyl)

294 The N-aroyl sulfoximine undergoes annulation with diphenylacetylene, delivering isoquinoli

295 Michael acceptors, serve as acceptors in the annulation with phthalides in the presence of LDA and pr

296 ridines by anilines followed by Pd-catalyzed annulation with propargyl carbonates gives rise to the f

297 cyclobutylanilines successfully undergo the annulation with terminal and internal alkynes to generat

298 s can engage in Pd-catalyzed oxidative (4+2) annulations with allenes, to produce highly valuable tet

299 unctionalizations proved amenable for alkyne annulations with high levels of regioselectivity and fun

300 riochlorins are modulated as a result of the annulation, with each isomer possessing a unique spectru