ライフサイエンスコーパス: anoxia

1 exposed to five, approximately 37 s bouts of anoxia.

2 ryo survival under one or two generations of anoxia.

3 the effluent source in response to sediment anoxia.

4 stressors such as heat, cold, crowding, and anoxia.

5 of patients who will not recover from brain anoxia.

6 face waters in response to expanded seafloor anoxia.

7 of low atmospheric O(2) or widespread marine anoxia.

8 bal warming and marine long-term hypoxia and anoxia.

9 generate cytotoxic Ca(2+) elevations during anoxia.

10 very observed in modern habitats affected by anoxia.

11 ii results in strong inhibition of CEF under anoxia.

12 ted genes and may have experienced long-term anoxia.

13 nted Src activation and Panx1 opening during anoxia.

14 distinguish low oxygen conditions from true anoxia.

15 toresuscitation in response to environmental anoxia.

16 oint convincingly to the transient spread of anoxia.

17 responding increase in the extent of oceanic anoxia.

18 growth, suggesting expression was induced by anoxia.

19 d only during eucapnic anoxia or hypercapnic anoxia.

20 s that become active when cells acclimate to anoxia.

21 ions, and glycogen, which is consumed during anoxia.

22 , promoting tumour growth and survival under anoxia.

23 trate respiration, arsenate respiration, and anoxia.

24 described for wild-type embryos subjected to anoxia.

25 um-free medium for 3 hours prior to onset of anoxia.

26 re was a more complex regulatory response to anoxia.

27 ery of respiration compared to acute hypoxia/anoxia.

28 xpression during acclimation of the cells to anoxia.

29 se conditions, and are motile after 24 hr of anoxia.

30 tal O2, thereby coordinating the response to anoxia.

31 e significantly increased in BMSCs following anoxia.

32 ontrast to [rho(-)] cells, did not die under anoxia.

33 nse of wild-type and daf-2(e1370) animals to anoxia.

34 nd displayed loss of the Mcl-1 protein under anoxia.

35 assessed by exposure of cells to 8 hours of anoxia.

36 by host neutrophils gives rise to regions of anoxia.

37 ologically hypoxic from lethal intracellular anoxia.

38 tinctions, climate fluctuations, and oceanic anoxia.

39 s, and increase in the anterior brain during anoxia.

40 RNA from the oxic zone to a max of 22% under anoxia.

41 usination and cellular resistance to hypoxia/anoxia.

42 abundance exhibit better survival under dark anoxia.

43 gradients and areas of near and almost total anoxia.

44 no ipso facto evidence for muscle dysoxia or anoxia.

45 glycogen provisioning when they experienced anoxia.

46 ironment by increasing embryo survival under anoxia.

47 lakes that vary in their vertical extent of anoxia.

48 (39.4%), cerebrovascular/stroke (25.8%), and anoxia (31.8%).

49 Tempranillo grapes were incubated in strict anoxia (75 degrees C x 24 h).

50 control pups to 15 episodes of environmental anoxia (97% N(2), 3% CO(2)).

51 Under anoxia a coordinated, cytoprotective program is induced,

52 h models demonstrated excessive mortality to anoxia (a postulated SIDS stressor) at P5 and P8.

53 rocurement for these donors included stroke, anoxia, acute disseminated encephalomyelitis, and mening

54 mbined with the lack of S-nitrosation during anoxia alone or by NO2(-) during normoxia places constra

55 tive metabolism of PR-104A and SN30000 under anoxia also showed little change in the POR knock-outs.

56 ession in A. limnaeus embryos in response to anoxia and aerobic recovery revealed small ncRNAs with e

57 ated (5 degrees C) turtles exposed to 9 days anoxia and compared the results with those for normoxic

58 se include traits for tolerating or avoiding anoxia and enabling underwater photosynthesis, traits th

59 ral waters, but also support hypotheses that anoxia and eutrophication in groundwater facilitate the

60 survival under subsequent longer exposure to anoxia and following engraftment in the infarcted heart.

61 In addition, both anoxia and GABA decreased excitatory postsynaptic activi

62 ous slow phasic GABAergic activity, and both anoxia and GABA reversibly induced SA by increasing GABA

63 val phenotype in that they survive long-term anoxia and high-temperature anoxia, do not accumulate si

64 ated with the gut micro-habitat (neutral pH, anoxia and increased carbon substrates).

65 t associations were for deaths attributed to anoxia and low Apgar (0-3) for term infants (RR 961.7, 9

66 However, the combination of anoxia and low pH led to colony death within 24 h.

67 hen hydrogen sulfide was added after 12 h of anoxia and low pH, colonies died after an additional 3 h

68 ed the marine biota resulting in episodes of anoxia and mass extinctions shortly after their eruption

69 likely contributed to the expansion of ocean anoxia and other environmental perturbations associated

70 appaB and ATF4-dependent transcription under anoxia and provides a regulatory feedback loop.

71 Our data suggest that spreading anoxia and redox cycling of harmful metals was a contrib

72 d that both GDH1 and GDH2 are induced during anoxia and reoxygenation and that this induction is medi

73 Functional characterization of anoxia and reoxygenation tolerance following uncoupling

74 on record of western North Pacific submarine anoxia and sea surface bioproductivity from the Chiba Se

75 rature proxy data indicate that the onset of anoxia and the extinction horizon coincide with both a r

76 ptional level in R. palustris in response to anoxia and the presence of benzoate and/or benzoyl-CoA (

77 obacteria are able to cope with water column anoxia and the role these microorganisms play in the det

78 bility in turtle cortical neurons exposed to anoxia and/or GABA(A/B) receptor (GABAR) modulators.

79 to mimic the fly's natural environments (wet anoxia) and relate findings to a typical gas induced env

80 e, is inducible by severe glucose depletion, anoxia, and acidosis.

81 ns of these mice show sensitivity to hypoxia/anoxia, and decreased adult neurogenesis was observed in

82 egrees C), salinity (26%), low light levels, anoxia, and high concentrations of heavy metals.

83 sand), indicative of an expansion of oceanic anoxia, and higher Th/U ratios (from 0.06 to 0.42), indi

84 ons, such as high light stress, cold stress, anoxia, and low levels of CO(2), fits with a role for Cr

85 showed that separate exposures to darkness, anoxia, and low pH did not cause mortality within 4 d.

86 puts have led to eutrophication, hypoxia and anoxia, and low pH.

87 ant stressors (e.g., sediment, low salinity, anoxia, and ocean acidification), offering an alternativ

88 ASB accumulation may contribute to sediment anoxia, and respiration of ASB and PHY-derived DOC may m

89 Brain insults, such as trauma, stroke, anoxia, and status epilepticus (SE), cause multiple chan

90 is a trait present in a very early phase of anoxia, and that ROS are needed for the regulation of a

91 relationship between cyanobacteria, sediment anoxia, and the ratio of dissolved nitrogen to soluble r

92 ng pressure that builds up upon the onset of anoxia, and this pressure can be relieved either by the

93 in ponds or soils often face hypoxia or even anoxia, and this severely impacts their physiology.

94 n is more damaging to mitochondria than near-anoxia; and (2) O suppresses ROS-induced damage to elect

95 controlling responses to reoxygenation after anoxia are evolutionarily conserved.

96 urface ocean O2 levels and pervasive benthic anoxia are expected in a world with much lower atmospher

97 prophase, or metaphase arrest in response to anoxia are not completely understood.

98 ia of freshwater lakes leading to deep-water anoxia are still not well understood, thereby constraini

99 Low oxygen gradients (hypoxia and anoxia) are important determinants of pathological condi

100 Ang-1 and Akt (MAAs) were more resistant to anoxia as compared with the nontransduced MSCs or those

101 ion greatly increased with acidosis and near-anoxia as occur in ischemic conditions.

102 ant mechanisms for cellular sustenance under anoxia as well as specific instances of post-transcripti

103 Cyanide-induced artificial anoxia, as well as a direct AMPK activator (A-769662) al

104 age of wines, 24 wines were stored in strict anoxia at 50 degrees C for 3weeks.

105 r quality in the Yamuna was very poor (e.g., anoxia at all sites), and blaNDM-1 abundances were high

106 ontrast, freshwater turtles survive weeks of anoxia at low temperatures without suffering from oxidat

107 ons with the distal slope being the focus of anoxia at these times, as well as short-lived episodes o

108 e, foundering, and marine burial followed by anoxia, bacterial colonization, sulfate reduction, and m

109 asting and cold-acclimation and further with anoxia, but disappeared within 30 min of ischemia in mou

110 consumption in FHM1 mice, leading to tissue anoxia, but moderate hypoxia, in WT mice.

111 of FDX5 causes a distinct delay in achieving anoxia by affecting photosynthetic O(2) evolution, accom

112 ion of AtNIP2;1 expression was observed upon anoxia challenge of Arabidopsis seedlings, with a 300-fo

113 The intensification of oceanic anoxia coincided with, or slightly preceded, the EH and

114 ps survived all 15 episodes of environmental anoxia, compared to 79% of control littermates (P = 0.00

115 ncreases in lipid production at the onset of anoxia, consistent with documented pathways of anoxic da

116 lta(15)N since ~1990 records an expansion of anoxia, consistent with observed O2 trends.

117 cking PLM, and correlates with impaired post-anoxia contractile function.

118 elation to 'traditional' limitations, namely anoxia, decay inhibiting compounds, low nutrients and ac

119 s indicate that [rho(0)] cells survive under anoxia despite the loss of Mcl-1 protein due to residual

120 Anoxia did not directly affect BK, but activated BK via

121 urvive long-term anoxia and high-temperature anoxia, do not accumulate significant tissue damage in e

122 score>/=1, donor age more than 51 years, and anoxia donor brain injury were associated with the highe

123 n biodiversity in response to enhanced ocean anoxia driven by anthropogenic release of greenhouse gas

124 lants from growth inhibition by flooding and anoxia, drought, high salt, the presence of fungal and b

125 ent anion channel in an isoform-specific and anoxia-enhanced manner and may be involved in the regula

126 embryo exposed to severe oxygen deprivation (anoxia) enters a state of suspended animation in which c

127 osynthetic microbes experience conditions of anoxia, especially during the night when photosynthetic

128 y values in the Hirnantian are not caused by anoxia/euxinia because euxinic biomarkers (maleimides an

129 ugh the causes of the early Toarcian Oceanic Anoxia Event (OAE) have been fairly well studied, the ev

130 s, the inactive state is not detected in the anoxia exposed npp-16 mutant.

131 und that CDK-1 localizes near chromosomes in anoxia-exposed embryos.

132 The half-cut pineapple fruit showed that the anoxia exposure completely inhibited internal transparen

133 The anoxia exposure delayed the increase in total sugar cont

134 In conclusion, the short-term anoxia exposure for 16h maintained postharvest quality,

135 The effects of short-term anoxia exposure for 16h on physicochemical changes of 'P

136 m these conditions but causes sensitivity to anoxia exposure.

137 hough inputs ceased in 1995, as indicated by anoxia extending at least 3 km down-gradient from the di

138 ng this time, episodes of local bottom-water anoxia extending into the photic-zone impacted the slope

139 Apoptosis induced by 12 hours of anoxia followed by 24 hours' reoxygenation was significa

140 isolated mitochondria subjected to 30 min of anoxia followed by reoxygenation were directly protected

141 rifuged and stored at 50 degrees C in strict anoxia for 2weeks (up to 7 in one case).

142 nditions can switch rapidly between oxia and anoxia, forcing soil bacteria to remodel their energy me

143 Anoxia has different impacts dependent upon both the dye

144 One such condition, anoxia, has yet to be extensively researched in V. vulni

145 derlies adaptation to a fluctuating normoxia-anoxia hatching environment by increasing embryo surviva

146 ions facing irregularly fluctuating normoxia-anoxia hatching environments failed to evolve randomizin

147 Periods of oceanic anoxia have had a major influence on the evolutionary hi

148 ically a consistent pattern of change during anoxia, highlighting this pathway as a potential solutio

149 The expansion of anoxia highlights the potential for rapid and discontinu

150 In vitro, anoxia/hypoxia induced an enrichment of miR-24 in endoth

151 taneous electrical activity is suppressed by anoxia (i.e., spike arrest; SA) and cell death does not

152 additional molecular events are triggered by anoxia in a HIF-1-independent manner, and these changes

153 ce P. aeruginosa motility under normoxia and anoxia in an isolate dependent manner.

154 unting for the continual PCr decrease during anoxia in both muscles.

155 is crucial for acclimation to high light and anoxia in both organisms.

156 Physical evidence of widespread anoxia in Cambrian oceans has remained elusive and thus

157 ooms and thermohaline stratification lead to anoxia in Chesapeake Bay bottom waters.

158 c carbon preservation associated with marine anoxia in Earth history.

159 sponse to prolonged episodes of bottom water anoxia in Ediacaran shelf and platform environments.

160 ibition of DHPS or DOHH induced tolerance to anoxia in immortalized mouse renal proximal cells.

161 is frequently subject to periods of dark and anoxia in its natural environment.

162 In order to evaluate the role of anoxia in levels of Hg enrichment several redox indicato

163 genetic and cellular responses to hypoxia or anoxia in oxygen-deprivation-tolerant organisms such as

164 report the novel rise of water-column shelf anoxia in the northern California Current system, a larg

165 Widespread anoxia in the ocean is frequently invoked as a primary d

166 Pervasive anoxia in the subsurface ocean during the Proterozoic ma

167 ery period, yet the vertical distribution of anoxia in the water column and its temporal dynamics thr

168 e catabolism modulates conditions like pH or anoxia in their symbionts' habitat.

169 Anoxia increased endogenous slow phasic GABAergic activi

170 presence of NO under normoxia but not under anoxia indicating that H(2)S does not react with NO but

171 of this pathway instigated a rapid onset of anoxia induced death in infected flies and increases in

172 Water column anoxia induced Fe(II) and As(III) fluxes from the sedime

173 Collectively, these results demonstrate that anoxia-induced cell death requires the loss of Mcl-1 pro

174 am regulators of Bax or Bak, did not prevent anoxia-induced cell death.

175 t in Bax and Bak or caspase-9 do not undergo anoxia-induced cell death.

176 ensitivity to viral infection by using DXV's anoxia-induced death pathology.

177 developmental responses to external stimuli: anoxia-induced developmental arrest in Drosophila embryo

178 GC7 treatment also attenuated anoxia-induced generation of reactive oxygen species in

179 ized from the aerobic metabolism of glucose; anoxia-induced impairment in retinal synaptic transmissi

180 Notably, anoxia-induced prophase arrest is suppressed in mutant e

181 We present evidence that by imposing an anoxia-induced reversible arrest of the cell cycle, the

182 The anoxia-induced shift of cells from an actively dividing

183 worms are first transitioned into a state of anoxia-induced suspended animation before cold exposure,

184 ability after prolonged arrest in a state of anoxia-induced suspended animation, implying that in suc

185 al of alternative reductant sinks (nitrate), anoxia induces autofermentation of carbohydrates with a

186 This challenges the common assumption that anoxia inherently protects soil C and illustrates the vu

187 In Chlamydomonas reinhardtii, dark anoxia is characterized by the activation of an extensiv

188 g P. aeruginosa dominance under normoxia and anoxia is greater than 3 kDa in size and is heat-stable.

189 monstrates that the regulation of ATF3 under anoxia is independent of 2-oxoglutarate dioxygenase, HIF

190 Thus, the response to anoxia is mediated by three pathways independently of HI

191 ility of animals exposed to brief periods of anoxia is prematurely arrested in gpd-2/3(RNAi) and daf-

192 Warming-induced anoxia is usually identified as main driver, but because

193 How cells die in the absence of oxygen (anoxia) is not understood.

194 ATF3 induction occurred most robustly under anoxia, is common, and it is not dependent on presence o

195 tions, including repetitive neuronal firing, anoxia, ischemia and hypoglycemic coma.

196 e (AD)-type neurofibrillary degeneration and anoxia-ischemia.

197 We conclude that activation of NMDARs during anoxia/ischemia recruits SFKs to open Panx1, leading to

198 cessive glutamate release during exposure to anoxia/ischemia.

199 sting activation by increased [Ca2+]c during anoxia, itself partly attributable to glutamate release.

200 and has been correlated with expanded marine anoxia lasting into the earliest Silurian.

201 g in flooded soils encounter hypoxia or even anoxia leading to poor seed germination and crop establi

202 After 7weeks of anoxia levels of free H2S and MeSH were high and similar

203 d DX-52-1 and exposed to etoposide in air or anoxia (<0.01% oxygen).

204 egulated by chronic (48 h) rather than acute anoxia (<24 h) by a complex set of pathways and mechanis

205 ronmental challenges presented by widespread anoxia may have been a prevalent if not dominant influen

206 hat increased endogenous GABA release during anoxia mediates SA by activating an inhibitory postsynap

207 Post-anoxia MEND is ablated in DHHC5-deficient hearts, inhibi

208 Our findings suggest that tissue anoxia might be a mechanism for prolonged aura in FHM1.

209 , the PHS donor was younger, male, died from anoxia, more likely to be HCV and antibody reacting to h

210 e was characterized by two pulses of oceanic anoxia, named the Lower and Upper Kellwasser events, dur

211 were rapidly converted from normoxia to near-anoxia ([O(2)], <1 micromol/L), the increase in H(2)DCF

212 Anoxia or exogenous NMDA activated Src family kinases (S

213 t-I discharges occurred only during eucapnic anoxia or hypercapnic anoxia.

214 by nitrite administered both in vitro during anoxia or in vivo 24 h before mitochondrial isolation.

215 ls are able to activate HIF-1 in response to anoxia or iron chelators during normoxia.

216 After a few minutes of anoxia or ischaemia, neurons in brain slices show a rapi

217 t are caused by enhanced metabolic activity, anoxia, or ischemia.

218 on of all three RAP2s conferred tolerance to anoxia, oxidative and osmotic stresses, and enhanced the

219 logies, epigenetic factors such as perinatal anoxia (PA) have been argued to be contributors, or caus

220 d that not only is the daf-2(e1370)-enhanced anoxia phenotype dependent upon gpd-2 and gpd-3, but als

221 es direct-rather than inferred-evidence that anoxia played a role in shaping a landmark Ediacaran eco

222 otheses of an extended period of whole-ocean anoxia prior to the end-Permian extinction.

223 al activation of the NF-kappaB pathway under anoxia protected cells from negative consequences of the

224 mental changes associated with the two ocean anoxia pulses.

225 roved the stratigraphic resolution of marine anoxia records 100-1000 fold using core-scanning X-Ray F

226 Whilst anoxia reduced the ability for P. aeruginosa CF isolates

227 ective perfusate that promotes recovery from anoxia, reduces reperfusion injury, prevents oedema, and

228 prolonged climatic perturbations and oceanic anoxia, related to the mass extinction.

229 In contrast to anoxia-related enhanced carbon storage in coeval open ma

230 rozoic deep ocean characterized by pervasive anoxia relative to the Phanerozoic (at least approximate

231 c assays showed that the level of GDH during anoxia-reoxygenation decreased in the ethylene-insensiti

232 We also studied mPTP opening after anoxia-reoxygenation in the presence or absence of extra

233 In parallel, following anoxia-reoxygenation these mitochondria generate less hy

234 n-2 depletion alone significantly attenuates anoxia-reoxygenation tolerance but uncoupling protein-3

235 GDH activity in metabolic adjustment during anoxia-reoxygenation.

236 mPTP opening in normoxic conditions or after anoxia-reoxygenation.

237 inferred the putative targets of EIN3 during anoxia-reoxygenation.

238 hepatocytes and mouse livers were exposed to anoxia/reoxygenation (A/R) and I/R, respectively.

239 human neuroblastoma cell line) subjected to anoxia/reoxygenation (A/R), a process that has been show

240 umulation likely protects turtle hearts from anoxia/reoxygenation injury and suggests metabolic inter

241 Mechanistic studies (in vitro anoxia/reoxygenation) demonstrated a mitochondrial site

242 TGF-beta expression are necessary to prevent anoxia/reoxygenation-induced apoptosis in mphi.

243 tects cultured lung epithelial cells against anoxia/reoxygenation-induced injuries.

244 We show that anoxia represents a powerful hierarchical preservation m

245 Cellular oxygen deprivation (hypoxia/anoxia) requires an acclimation response that enables su

246 This system allows anoxia-resistant animals and mammalian cells to initiate

247 In addition to their anti-fatigue and anti-anoxia roles in traditional medicine, Rhodiola total ext

248 tion component, such as transient hypoxia or anoxia, root waterlogging, or complete submergence.

249 e pathway resulted in similar rapid onset of anoxia sensitivity, it also resulted in decreased viral

250 ed oocytes by heat shock, osmotic stress, or anoxia, similar to the induction of stress granules in m

251 ed variations in the extent of North Pacific anoxia since 1850 using a geochemical proxy for denitrif

252 ced bioreductive metabolism of PR-104A in an anoxia-specific manner.

253 s exquisitely sensitive to water logging and anoxia stress.

254 npp-5 mutants are hypersensitive to anoxia, suggesting that the spindle assembly checkpoint

255 Anoxia suppressed total C loss by 27% in the Oxisol and

256 increased sensitivity to osmotic stress and anoxia, surprisingly we found that the mitochondrial fus

257 s, the daf-2(e1370) animals have an enhanced anoxia-survival phenotype in that they survive long-term

258 enes that suppress the daf-2(e1370)-enhanced anoxia-survival phenotype.

259 ameliorates the uncoupling protein-depleted anoxia-susceptible phenotype.

260 However, anoxia sustained or even increased decomposition of nati

261 (S-MIF), an Archean signature of atmospheric anoxia that begins to disappear from the rock record at

262 als of cooling and deepening of water column anoxia that expanded the habitable mid-water refuge zone

263 etazoans, and be responsible for the oceanic anoxia that has puzzled so many researchers for so many

264 gs to a typical gas induced environment (dry anoxia) that is commonly used in a laboratory.

265 the subsequent development of shallow-water anoxia, the hallmark of the T-OAE.

266 During anoxia, the naked mole-rat switches to anaerobic metabol

267 esis in this mutant when it was placed under anoxia; the two other ADH homologs encoded on the Chlamy

268 generated in the mitochondria in response to anoxia, though the precise mechanism of biosynthesis rem

269 This work extends the duration of anoxia to >3 Myrs - notably longer than well-studied Mes

270 synthetic organisms like C. reinhardtii from anoxia to high light to limitations imposed at the level

271 tic carbon fixation during a shift from dark anoxia to light.

272 Anoxia tolerance and physiology vary by developmental st

273 uncoupling protein-3 in modulating ischemia/anoxia tolerance in heart-derived cells.

274 coupling protein-3 depletion does not reduce anoxia tolerance.

275 lating gene expression that supports extreme anoxia tolerance.

276 mbryos and isolated cells exhibiting extreme anoxia tolerance.

277 n patterns that suggest a role in supporting anoxia tolerance.

278 habit ephemeral ponds, producing drought and anoxia-tolerant embryos, which allows the species to per

279 Conversely, in anoxia-tolerant turtle brain, spontaneous electrical act

280 llifish Austrofundulus limnaeus are the most anoxia-tolerant vertebrate.

281 For example, the most anoxia-tolerant vertebrates, painted turtles and crucian

282 iratory rate of the fruit was induced by the anoxia treatment.

283 Anoxia triggered the loss of the Mcl-1 protein upstream

284 In contrast, anoxia underlying oligotrophic surface ocean conditions

285 Cold shock and anoxia upregulates a homologue of HU (Hlp) in Mycobacter

286 ability to withstand episodic environmental anoxia via autoresuscitation.

287 xygenation after prolonged and acute hypoxia/anoxia was compared.

288 ing supports the idea that widespread marine anoxia was induced by a greenhouse-driven weathering pul

289 allenged the fundamental premise that muscle anoxia was requisite for increased muscle and blood [La(

290 To determine how turtles survive prolonged anoxia, we measured ~80 metabolites in hearts from cold-

291 Etoposide IC(50) values in anoxia were 3-fold higher than those in air for HT1080 (

292 t levels of hypoxia (mild, moderate, severe, anoxia) were used to produce a wide range of [Ca(2+) ]i

293 ical quenching mechanism, in relationship to anoxia where the activity of cyclic electron flow is sti

294 Under anoxia, where CEF is induced, quantitative proteomics ev

295 ean anoxic event has focused on the onset of anoxia, with global reconstructions based on carbonate d

296 may be released during flooding-induced soil anoxia, with the degree of mobilization being affected b

297 urnover events occurred: (i) at the onset of anoxia, with the extinction of most benthic species and

298 vive 18 minutes of total oxygen deprivation (anoxia) without apparent injury.

299 This enhanced bioproductivity and anoxia would have resulted in elevated rates of organic

300 depth-dependent metabolic costs for grazers, anoxia zones, available food, and visual predation.