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2 ived mature dendritic cells (DC) loaded with anti-idiotype 3H1 or CEA could reverse CEA unresponsiven
9 proach that is analogous to the isolation of anti-idiotype antibodies and were able to isolate peptid
14 characterize the structural footprint of an anti-idiotype antibody (E1) specific for a potent, fully
16 s studies suggested that vaccination with an anti-idiotype antibody 3H1, which mimics a specific epit
17 se unconfirmed (CR/CRu) to CVP and making an anti-idiotype antibody are 2 independent factors that ea
21 data demonstrate the utility of employing an anti-idiotype antibody to monitor a patient's specific i
22 ound to inhibit mAb HGAC 39.G3 binding to an anti-idiotype antibody with approximately 1000-fold grea
23 rcinoembryonic antigen (CEA), and that of an anti-idiotype antibody, 3H1, which mimics CEA and can be
27 ve demonstrated the general applicability of anti-idiotype aptamers as capture reagents in quantifica
29 , day 112, and day 168) were assessed via an anti-idiotype binding assay and characterised via non-co
30 nhibitor protein (BLA-BLIP) complex with two anti-idiotype binding proteins (Affimer proteins) as rec
31 ntibody elicits an anti-antibody response or anti-idiotype, consequently producing a disease-inciting
34 phoma based on tumor idiotype (Id) has shown anti-idiotype humoral immune responses in 40%-50% and ce
38 rall survival of all 20 patients mounting an anti-idiotype immune response are significantly prolonge
39 eeded to prove a causal relationship between anti-idiotype immunity and improved clinical outcome.
41 We determined the crystal structure of two anti-idiotypes in complex with iglb12 and used these ant
42 nization with a multimerized version of this anti-idiotype induced the proliferation of transgenic mu
44 cluding the case previously studied using an anti-idiotype, involvement of the splenic marginal zone
45 with the experimental fact that the level of anti-idiotypes is low in autoimmune patients but high in
46 mAb GH1002 was elicited with the syngeneic anti-idiotype mAb MK2-23 which mimics the determinant de
47 cular adjuvant peptide is crosslinked to the anti-idiotype mimetic by chemical means without modifyin
49 vizumab as a synthetic cytokine and a set of anti-idiotype nanobodies (AIP(VHH)) as synthetic recepto
50 d anti-idiotype vaccines and identified that anti-idiotype nanobodies could mimic the antigen on amin
51 bs against different pathogens are prepared, anti-idiotype nanobody vaccines can be easily produced a
52 TANCEAnti-idiotype vaccines utilize idiotype-anti-idiotype network theory, eliminating the need for e
55 he first detailed molecular comparison of an anti-idiotype paratope specific for a human antibody wit
56 demonstrate that the resultant semisynthetic anti-idiotype peptibodies kill tumor cells in vitro with
57 hybridoma-generated vaccines, we found that anti-idiotype production was even more highly associated
59 mmunity through a network involving idiotype-anti-idiotype reactions termed 'autoantigen complementar
61 reatment with CAMPATH-1H can lead to patient anti-idiotype responses which may be exacerbated by the
63 st detailed molecular comparison between the anti-idiotype surface and its analogous epitope located
65 ft, the bystander effect, molecular mimicry, anti-idiotype theory, antigenic complementarity, and dua
66 otypes in complex with iglb12 and used these anti-idiotypes to identify rare naive human B cells expr
69 ided a strategy for producing nanobody-based anti-idiotype vaccines and identified that anti-idiotype
71 er, the commercial production of traditional anti-idiotype vaccines using monoclonal and polyclonal a