ライフサイエンスコーパス: antiandrogenic

1 If DDE has important antiandrogenic action in humans, it may be manifest only

2 thoxyphenyl)-1,3-propanedione] showed potent antiandrogenic activities and were superior to hydroxyfl

3 These unique antiandrogenic activities make ADEK a potential therapeu

4 dicated that the two oils had estrogenic and antiandrogenic activities.

5 ha and ERbeta agonist activity that retained antiandrogenic activities.

6 Vinclozolin is a pesticide with antiandrogenic activity as an endocrine disruptor compou

7 hemicals is challenging and a great share of antiandrogenic activity detected in the environment has

8 oncentrated water extract that was posing an antiandrogenic activity equal to 45.5 (+/-13.7 SD) FEq/L

9 others (17 and 19) appear to exhibit strong antiandrogenic activity in cultures of the LNCaP human p

10 Finally, the antiandrogenic activity of C47 and one derivate was conf

11 We speculate that the antiandrogenic activity of p,p'-DDE may mitigate harmful

12 (trifluoromethyl)benzonitrile (6a), exhibits antiandrogenic activity significantly greater than that

13 Antiandrogenic activity was also evaluated in LNCaP cell

14 Notably, 6a maintains its antiandrogenic activity with AR mutants W741L and T877A

15 ropanol-based ligands possessing significant antiandrogenic activity with both wild-type AR and the t

16 n bond donor group were also crucial for the antiandrogenic activity, which is consistent with previo

17 e products and their reported estrogenic and antiandrogenic activity.

18 ules seem to be important factors related to antiandrogenic activity.

19 oxysteroid dehydrogenase 2 and are therefore antiandrogenic and antiestrogenic.

20 enic activity appears to be unrelated to the antiandrogenic and antimineralocorticoid effects of spir

21 anomalies and environmental factors, such as antiandrogenic and estrogenic endocrine disrupting chemi

22 d cellular and molecular mechanisms by which antiandrogenic and estrogenic signals induce penile malf

23 yl group at ring A is important for TS-IIA's antiandrogenic and maspin induction activities.

24 Nevertheless, high antiandrogenic and minor dioxin-like and estrogenic effe

25 s (61 women with androgenic COC use, 59 with antiandrogenic COC use, 60 women with a menstrual cycle

26 to the endocrine disruptors vinclozolin (an antiandrogenic compound) or methoxychlor (an estrogenic

27 In particular, many pesticides are antiandrogenic, creating a need for robust and sensitive

28 ven their close structural similarity to the antiandrogenic drug nilutamide.

29 nzalutamide (MDV3100) is a second-generation antiandrogenic drug that was approved by the Food and Dr

30 e disease susceptibility in men and identify antiandrogenic drugs as candidate therapeutics for COVID

31 Treatment with antiandrogenic drugs reduced ACE2 expression and protect

32 It demonstrated a noticeable antiandrogenic effect on prostate in intact rats with en

33 TDI) values (considered as potential adverse antiandrogenic effect).

34 Phthalates have antiandrogenic effects and may disrupt lipid and carbohy

35 t estrogenic, antiestrogenic, androgenic, or antiandrogenic effects by influencing estrogen or androg

36 alpha (gmAra), several bisphenols exhibited antiandrogenic effects by inhibiting gmAra activity.

37 agents, many of which are antioxidants with antiandrogenic effects, are being tested (or soon will b

38 ates reached levels that might cause adverse antiandrogenic effects.

39 ed germ cells (MNGs) in fetal testes without antiandrogenic effects.

40 yl or difluoropropyl substituents to abolish antiandrogenic effects.

41 In the present study, we assessed the antiandrogenic efficacy of isosilybin B employing human

42 Untreated wastewater induced antiandrogenic, estrogenic, antiestrogenic, and retinoid

43 We propose that the antiandrogenic exposure during early development may sim

44 als that also may contribute to a cumulative antiandrogenic exposure.

45 whose progenitors had been treated with the antiandrogenic fungicide vinclozolin.

46 (estrogenic, antiestrogenic, androgenic, and antiandrogenic) in vitro and in vivo.

47 strong and direct evidence for ascribing an antiandrogenic MOA to BPA in vertebrates.

48 itigate the impact of TB, consistent with an antiandrogenic MOA.

49 lations are regularly exposed to mixtures of antiandrogenic pesticides, our results underline the nee

50 A new nonsteroidal antiandrogenic pharmacophore has been discovered using c

51 Multiple antiandrogenic phthalates exposure during fetal developm

52 at DIM exhibits potent antiproliferative and antiandrogenic properties in androgen-dependent human pr

53 shown to have estrogenic, antiestrogenic, or antiandrogenic properties; as a result, the impact of ex

54 ly greater than that of the most widely used antiandrogenic prostate cancer drugs bicalutamide (1) an

55 ver, this series of aryl hydantoins produced antiandrogenic side effects in the host, a not unexpecte

56 estive heart failure, the progestational and antiandrogenic side effects of the nonspecific aldostero

57 igh antischistosomal efficacy that were less antiandrogenic than 1.

58 Therefore, we analyzed whether antiandrogenic therapy with finasteride, which inhibits