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1 of 40 derivatives of clofilium, a class III antiarrhythmic agent.
2 and these findings support its utility as an antiarrhythmic agent.
3 factors, when patients are treated with this antiarrhythmic agent.
4 c calcium channel, and therefore a potential antiarrhythmic agent.
5 story of diabetes mellitus, and prior use of antiarrhythmic agents.
6 sis after excluding patients on pre-existing antiarrhythmic agents.
7 d susceptibility to proarrhythmic effects of antiarrhythmic agents.
8 jority of patients, necessitating the use of antiarrhythmic agents.
9 c drug development from class I to class III antiarrhythmic agents.
10 ate hERG currents and thus may act as potent antiarrhythmic agents.
11 nnel in heart, is a major target for class I antiarrhythmic agents.
13 ee of atrial fibrillation without the use of antiarrhythmic agents; 84% were arrhythmia free when tho
14 In vitro and in vivo studies suggest that antiarrhythmic agents affect Na+ channels of cells from
17 ed to investigate the cellular uptake of the antiarrhythmic agent amiodarone, a phospholipidosis-indu
18 was reported in 1 of 1 RCT (100%) of class 1 antiarrhythmic agents and 5 of 5 RCTs (100%) of warfarin
19 drugs with narrow therapeutic indexes (e.g., antiarrhythmic agents, anticoagulant agents) have demons
24 brillation; the indications for conventional antiarrhythmic agents are decreasing because of side eff
25 lantable cardioverter defibrillators (ICDs), antiarrhythmic agents are increasingly being used as adj
30 incipal mechanisms of action of contemporary antiarrhythmic agents, delineates their limitations in t
33 heteroaromatic derivatives of the class III antiarrhythmic agent dofetilide was synthesized and asse
34 a(2+) release events and the response to the antiarrhythmic agent flecainide in Purkinje cells and ve
38 of intravenous dofetilide, a pure class III antiarrhythmic agent, for the termination of sustained a
39 ollowed by the rapid, sequential infusion of antiarrhythmic agents (i.e., adenosine, verapamil, and e
41 mechanistic insights into the effects of the antiarrhythmic agents in the setting of AF-induced SND.
44 s, range: 1 to 241 days) failed at least two antiarrhythmic agents including either flecainide or sot
45 ompared with baseline (P:<0.001), but use of antiarrhythmic agents increased marginally (P:=0.05).
46 The Vaughn Williams classification divides antiarrhythmic agents into four groups according to thei
49 tter in humans by ibutilide, a new class III antiarrhythmic agent, is characterized by an increase in
51 isproportionate reporting similar to that of antiarrhythmic agents known to promote torsade de pointe
53 gest that sodium channel block with class IB antiarrhythmic agents may be effective in suppressing Td
54 ) for whom digoxin monotherapy and secondary antiarrhythmic agents (n=13) were not effective were tre
55 xamined the effect of ibutilide, a class III antiarrhythmic agent, on the energy requirement for atri
57 concomitant, postcardioversion therapy with antiarrhythmic agents, patients will frequently have add
60 ocytes expressing Kv1.5-GFP with the class I antiarrhythmic agent quinidine resulted in a dose- and t
63 de fumarate is an intravenous (IV) class III antiarrhythmic agent that has been shown to be significa
64 ide fumarate is an investigational class III antiarrhythmic agent that prolongs repolarization by inc
66 ntial administration of different classes of antiarrhythmic agents until conversion to sinus rhythm w
67 neous influences of direct current shock and antiarrhythmic agents, which may independently depress l
68 hibit KvLQT1, whereas clofilium, a class III antiarrhythmic agent with the propensity to induce torsa
69 hus, there is a recognized need for improved antiarrhythmic agents with actions that are selective fo
70 a that it may be possible to develop class I antiarrhythmic agents with optimized pharmacodynamic pro