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1 nherent mutator activity that helps generate antibody diversity.
2 ing RNA surveillance machinery in generating antibody diversity.
3 n addition to its integral roles in creating antibody diversity.
4  of the vertebrate immune system to generate antibody diversity.
5 two types of genomic alterations to increase antibody diversity.
6 matic hypermutation mechanism that increases antibody diversity.
7 n many vertebrates, and is a major source of antibody diversity.
8    As a model for studying the generation of antibody diversity, a gene-targeted mouse was produced t
9                  We hypothesized that higher antibody diversity across recent H1 and H3 influenza vir
10                                              Antibody diversity analysis revealed immunodominant anti
11 permutation contributes to the generation of antibody diversity and is strongly associated with the m
12 ficity suggest new mechanisms for generating antibody diversity and polyreactivity (multispecificity)
13 ombination is integral to the development of antibody diversity and proceeds through a complex DNA cl
14 pinned by impaired generation of appropriate antibody diversity and quantity.
15 s, we deploy transgenic mice mimicking human antibody diversity and somatic hypermutation (SHM) and i
16  DNA sequence preferences upon generation of antibody diversity, and the results have implications fo
17  inefficient, haphazard deamination produces antibody diversity associated with AID.
18          We report here that, in the case of antibodies, diversity at one of these regions, CDR3 of t
19 isons reveal a high level of conservation in antibody diversity between the lymph node and spleen and
20 ene may not merely be a sequence restricting antibody diversity, but is potentially a novel receptor
21                                              Antibody diversity creates an immunoregulatory challenge
22 ogical processes including the generation of antibody diversity, DNA replication in a number of virus
23                                The origin of antibody diversity has intrigued scientists for nearly a
24 prehensive, chip-based method to display the antibody diversity in an individual on peptide arrays.
25 chain 3, providing a unique perspective into antibody diversity in antigen recognition.
26 uced deoxycytidine deaminase (AID) generates antibody diversity in B cells by initiating somatic hype
27 s switching is crucial for the generation of antibody diversity in humoral immunity and, when deregul
28 outcomes of this study give a glimpse of the antibody diversity inherent in human plasma used to manu
29 y to rearrange the germ-line DNA to generate antibody diversity is an essential prerequisite for the
30  mystery surrounding the mechanisms by which antibody diversity is generated was largely settled in t
31                                              Antibody diversity is initiated by activation-induced de
32                     Our results suggest that antibody diversity is not limited by the sequences encod
33                                              Antibody diversity occurs randomly as B cells recombine
34                                              Antibody diversity primarily arises from V(D)J recombina
35 gnature technology is unbiased in displaying antibody diversity relative to natural sequence space, a
36                                          The antibody diversity required to achieve this is believed
37  and memory cells; and how each path impacts antibody diversity, selectivity, and affinity.
38       These findings suggest that increasing antibody diversity through prolonged or repeated antigen
39 ibody variable and switch regions, promoting antibody diversity through somatic hypermutation or clas
40                                    Increased antibody diversity to seasonal influenza viruses was ass
41 irst structurally profile naive ('baseline') antibody diversity using snapshots from 41 unrelated ind
42 two mutagenic DNA processes used to generate antibody diversity via the B-cell mutator protein activa
43 preserve extracellular epitopes and optimize antibody diversity, we generated monoclonal antibodies t