ライフサイエンスコーパス: antibody-secreting cell

1 n of both TI-2 memory B cells and long-lived antibody secreting cells.

2 , indicating local maintenance of protective antibody secreting cells.

3 icroneutralisation titres, and the number of antibody secreting cells.

4 le to screening both bacterial and mammalian antibody secreting cells.

5 systemic antigen-specific IgG(+) and IgA(+) antibody secreting cells.

6 stigation of differentiation of B cells into antibody secreting cells.

7 tiation of Foxp3+ regulatory T cells and IgA antibody-secreting cells.

8 ional and morphological differentiation into antibody-secreting cells.

9 d native antigens and differentiate into VLR antibody-secreting cells.

10 tion of the preexisting and newly-developing antibody-secreting cells.

11 on, class switching and differentiation into antibody-secreting cells.

12 ant increases in the numbers of specific IgA antibody-secreting cells.

13 lection and maturation into broadly-reacting antibody-secreting cells.

14 um responses and developed S. typhi-specific antibody-secreting cells.

15 ntibody to hepatitis pre-S or pre-S-specific antibody-secreting cells.

16 rotavirus, as determined by assay of mucosal antibody-secreting cells.

17 sion and the differentiation of B cells into antibody-secreting cells.

18 ndrial homeostasis and alterations in GC and antibody-secreting cells.

19 lergen tolerance through apoptosis of IgE(+) antibody-secreting cells.

20 production, and failed to differentiate into antibody-secreting cells.

21 decreased the expression of Xbp1 in Blimp1+ antibody-secreting cells.

22 ero-mammary link may exist for food-specific antibody-secreting cells.

23 ation of human B cells into memory cells and antibody-secreting cells.

24 and preserved ability to differentiate into antibody-secreting cells.

25 B-cells, cycling/germinal center B-cells and antibody-secreting cells.

26 IgG class switching, and differentiated into antibody-secreting cells.

27 ing, and increased the numbers of anti-HIV-1 antibody-secreting cells.

28 emory B cells and no evidence of circulating antibody-secreting cells.

29 T-dependent B cell memory and high affinity antibody-secreting cells.

30 rapid conversion of naive B cells to mature antibody-secreting cells.

31 ntibodies (blood and stool) and RBD-specific antibody-secreting cells.

32 the TIV group and correlated with number of antibody-secreting cells.

33 nd facilitates differentiation of long-lived antibody-secreting cells.

34 The increase in frequency of donor-specific antibody-secreting cells after renal transplantation ind

35 ncies of memory B cells and antigen-specific antibody-secreting cells after vaccination.

36 ease in antibody titer, reduced frequency of antibody secreting cells, an absence of affinity maturat

37 a, and this colonization induced significant antibody-secreting cell and enzyme-linked immunosorbent

38 ish 10 mo postchallenge led to activation of antibody-secreting cells and a more rapid production of

39 cific B and T cells after i.n. immunization, antibody-secreting cells and antigen-responsive T cells

40 nduced high levels of S-specific IgG and IgA antibody-secreting cells and antigen-specific CD4(+) T c

41 also led to increased levels of HIV-specific antibody-secreting cells and B cell-associated chemokine

42 this article, we will review the biology of antibody-secreting cells and focus on therapeutics that

43 NP-specific antibody-secreting cells and heightened frequencies of g

44 carrier protein, leading to large numbers of antibody-secreting cells and high titers of high-affinit

45 follicular helper cells correlates with peak antibody-secreting cells and influenza heamaglutinin-spe

46 Moreover, significantly lower numbers of IgG antibody-secreting cells and lower levels of CD4(+)-T-ce

47 irus strain correlate with low production of antibody-secreting cells and memory B cells recognizing

48 Antibody-secreting cells and memory B cells specific for

49 uction of higher levels of envelope-specific antibody-secreting cells and memory B cells, higher IgG

50 veals the capacity of memBcs to develop into antibody-secreting cells and present an idea for a new c

51 inhibitor to murine BMI-1, we could deplete antibody-secreting cells and prohibit detrimental immune

52 RSV-specific, T-cell-dependent neutralizing antibody-secreting cells and RSV-specific memory respons

53 sma cell subsets, such as early-minted blood antibody-secreting cells and the bone marrow LLPC, and h

54 es to SARS-CoV-2, including the frequency of antibody-secreting cells and the presence of SARS-CoV-2-

55 (NV-specific IgA and immunoglobulin G [IgG] antibody-secreting cells and total and NV-specific IgA a

56 y lower levels of germinal center formation, antibody-secreting cells, and circulating influenza viru

57 l center (GC) reaction, increased anti-gp120 antibody-secreting cells, and increased anti-gp120 funct

58 ve rise to class-switched memory B cells and antibody-secreting cells, and likely contribute signific

59 indings show that memory B cells and natural antibody-secreting cells are BLyS-independent and sugges

60 These antibody-secreting cells are part of a larger subset of

61 We identified antibody-secreting cells as the major splenic B cell pop

62 specifically the impact on the maturation of antibody-secreting cells, as a potential mechanism under

63 Because gut IgA+ antibody secreting cells (ASC) are poorly defined a flow

64 owing infection or vaccination, early-minted antibody secreting cells (ASC) or plasmablasts appear in

65 Immunoglobulin in cerebral spinal fluid and antibody secreting cells (ASC) within the central nervou

66 gamma producing cells (IFN-gamma PC) and IgA antibody secreting cells (ASC).

67 Antibody-secreting cell (ASC) and memory B-cell (MBC) re

68 The transcriptional network regulating antibody-secreting cell (ASC) differentiation has been e

69 ly elevated circulating immunoglobulin (Ig)G antibody-secreting cell (ASC) frequencies and hypergamma

70 vestigated the kinetics of the FMDV-specific antibody-secreting cell (ASC) response following homolog

71 A dose-related, immunoglobulin A antibody-secreting cell (ASC) response to S. flexneri 2a

72 ve increases in humoral and antigen-specific antibody-secreting cell (ASC) responses after each dose

73 measure local and systemic isotype-specific antibody-secreting cell (ASC) responses to individual st

74 interferon-gamma (IFN-gamma) and long-lived antibody-secreting cell (ASC) responses, the roles for I

75 IgG responses, and all but one volunteer had antibody-secreting cell (ASC) responses.

76 Isotype-specific antibody-secreting cells (ASC were enumerated at selecte

77 In vivo antigen-activated antibody-secreting cells (ASC) (effector B cells) and in

78 on-isotype-switched, memory (Bmem) cells and antibody-secreting cells (ASC) accumulate in various mod

79 id differentiation to become HA-specific IgG antibody-secreting cells (ASC) after activation in non-T

80 aluated immunoglobulin M (IgM), IgA, and IgG antibody-secreting cells (ASC) and cytokine-secreting ce

81 eir antibody affinity and differentiate into antibody-secreting cells (ASC) and memory cells.

82 Antibody-secreting cells (ASC) and serum antibody titers

83 r immunoglobulin A (IgA) and IgG circulating antibody-secreting cells (ASC) and stimulated memory B c

84 Antibody-secreting cells (ASC) are the effectors of prot

85 responses were determined from the number of antibody-secreting cells (ASC) in blood measured by enzy

86 ified by the frequency of influenza-specific antibody-secreting cells (ASC) in peripheral blood, was

87 ibody titers, and significant numbers of IgG antibody-secreting cells (ASC) in the spleen and tracheo

88 induced activation and differentiation into antibody-secreting cells (ASC) of CBC but not IBC when t

89 F-specific antibodies and fewer 23F-specific antibody-secreting cells (ASC) than did BALB/c or (CBA/J

90 hat were associated with the localization of antibody-secreting cells (ASC) to the bone marrow.

91 cle-treated mice, virus-specific IgM and IgG antibody-secreting cells (ASC) were decreased 22- and 45

92 To assess correlates of protection, antibody-secreting cells (ASC) were enumerated in intest

93 The highest numbers of antibody-secreting cells (ASC), both IgA and IgG, were d

94 potent and selective chemoattractant for IgA antibody-secreting cells (ASC), efficiently recruiting I

95 FMDV-specific antibody-secreting cells (ASC), predominantly IgM, were

96 rast, in STV there was a lack of circulating antibody-secreting cells (ASC), reflecting the local muc

97 tactivated B-cell subsets, including MBC and antibody-secreting cells (ASC), with maximal expression

98 s, with only a fraction differentiating into antibody-secreting cells (ASC).

99 rders are often associated with retention of antibody-secreting cells (ASC).

100 nature and homing potentials of circulating antibody-secreting cells (ASC).

101 Active SLE generates increased circulating antibody-secreting cells (ASC).

102 IgM(-) memory B cells (B(mem)), and CD138(+) antibody-secreting cells (ASC).

103 We analyzed the humoral responses (HI, antibody-secreting cell [ASC], and serum immunoglobulin

104 ibody responses (measured by quantitation of antibody-secreting cells [ASC] in intestinal and systemi

105 he mean numbers of HSV glycoprotein-specific antibody secreting cells (ASCs) and IFN-gamma SCs were g

106 Antibody secreting cells (ASCs) are critical effector ce

107 anut IgE levels, symptoms, or numbers of IgE antibody secreting cells (ASCs) in the BM.

108 HPV-specific antibody secreting cells (ASCs) were present in the tumo

109 ples were collected for serological profile, antibody secreting cells (ASCs), and analysis of ASC hom

110 influenza infection, the clonal dynamics of antibody secreting cells (ASCs), particularly those with

111 entification and recovery of target specific antibody secreting cells (ASCs).

112 pecificity and duration of circulating human antibody-secreting cells (ASCs) after vaccination have b

113 oglobulin A (IgA) and immunoglobulin G (IgG) antibody-secreting cells (ASCs) and influenza virus-spec

114 Antigen-specific B cells bifurcate into antibody-secreting cells (ASCs) and memory B cells (MBCs

115 Antibody-secreting cells (ASCs) and memory B cells (MemB

116 ted a robust expansion of the virus-specific antibody-secreting cells (ASCs) and memory B cells in th

117 Antibody-secreting cells (ASCs) are considered work hors

118 Antibody-secreting cells (ASCs) are isolated from whole

119 We demonstrate that B cells and antibody-secreting cells (ASCs) are present in inflammat

120 Antibody-secreting cells (ASCs) are present in the CNS a

121 rbent assay (ELISA), and total IgG and dsDNA antibody-secreting cells (ASCs) by enzyme-linked immunos

122 ined that the measurement of Mp-specific IgM antibody-secreting cells (ASCs) by enzyme-linked immunos

123 measurement of Mp-specific immunoglobulin M antibody-secreting cells (ASCs) by enzyme-linked immunos

124 was to test the contribution of allospecific antibody-secreting cells (ASCs) from different anatomica

125 on in secondary lymphoid organs, a subset of antibody-secreting cells (ASCs) homes to the bone marrow

126 neumoniae (Mp)-specific immunoglobulin (Ig)M antibody-secreting cells (ASCs) improved diagnosis of Mp

127 pecific immunoglobulin A (IgA), IgG, and IgM antibody-secreting cells (ASCs) in a dose-responsive man

128 ons through the generation of class-switched antibody-secreting cells (ASCs) in germinal centers.

129 influenza-, tetanus- or SARS-CoV-2-specific antibody-secreting cells (ASCs) in long-lived plasma cel

130 Germinal centers and antibody-secreting cells (ASCs) in spleens and IgG depos

131 s-specific antibodies and rotavirus-specific antibody-secreting cells (ASCs) in the circulation to pr

132 otype, magnitude, and tissue distribution of antibody-secreting cells (ASCs) in the intestinal and sy

133 The accumulation of immunoglobulin (Ig)A antibody-secreting cells (ASCs) in the lactating mammary

134 Bmem cells differentiated more rapidly into antibody-secreting cells (ASCs) in vitro.

135 The terminal differentiation of B cells into antibody-secreting cells (ASCs) is a critical component

136 erentiation of naive and memory B cells into antibody-secreting cells (ASCs) is a key feature of adap

137 Differentiation of B cells into antibody-secreting cells (ASCs) is a key process to gene

138 B cell differentiation into antibody-secreting cells (ASCs) is a tightly regulated p

139 cell transition to memory B cells (MBCs) and antibody-secreting cells (ASCs) is crucial for clinical

140 Antibody-secreting cells (ASCs) or plasma cells secrete

141 ive-derived, low-mutation IgG1 population of antibody-secreting cells (ASCs) reflecting features of l

142 HBsAg-specific antibody-secreting cells (ASCs) response was not differe

143 Here, we examined the lifespan of IgE antibody-secreting cells (ASCs) to determine whether the

144 dance of molecules involved in the homing of antibody-secreting cells (ASCs) to the bone marrow (BM).

145 n-reactivities were more concentrated within antibody-secreting cells (ASCs) versus B cells (P < 0.00

146 0, 1, and 3 months, and serum antibodies and antibody-secreting cells (ASCs) were assessed.

147 Frequencies of influenza-specific antibody-secreting cells (ASCs) were measured by enzyme-

148 ced memory T cell responses or PnPS-specific antibody-secreting cells (ASCs) were responsible for ser

149 s erythematosus (SLE) courses with surges of antibody-secreting cells (ASCs) whose origin, diversity

150 vaccination for the number of Spike-specific antibody-secreting cells (ASCs) with a mucosal tropism.

151 hemagglutination inhibition (HAI) activity, antibody-secreting cells (ASCs), and HA-specific compart

152 ) and immunoglobulin G (IgG), fecal IgA, IgA antibody-secreting cells (ASCs), and IFN-gamma productio

153 evated nasal IL-5 levels and high numbers of antibody-secreting cells (ASCs), including plasma cells

154 ls and their subsequent differentiation into antibody-secreting cells (ASCs).

155 d and tested by ELISpot for antigen-specific antibody-secreting cells (ASCs).

156 he differentiation of naive B cells (nBs) to antibody-secreting cells (ASCs).

157 h inter-individual convergence in memory and antibody-secreting cells (ASCs).

158 out IL-6 as a differentiation factor for IgM antibody-secreting cells (ASCs).

159 ng immunoglobulin G (IgG) antibodies and IgG antibody-secreting cells (ASCs).

160 ulting from significantly reduced numbers of antibody-secreting cells (ASCs).

161 he CNS were primarily CD8(+) T cells and IgM antibody-secreting cells (ASCs).

162 Antibody-secreting cells (ASCs; plasma cells and plasmab

163 differentiation of autoreactive B cells into antibody-secreting cells, but it is not necessary for th

164 y enzyme-linked immunosorbent assay and lung antibody secreting cells by enzyme-linked immunospot ass

165 ed using Luminex assays and the frequency of antibody-secreting cells by ELISpot.

166 relied on conversion of memory B cells into antibody-secreting cells by in vitro culture.

167 tavirus-specific, immunoglobulin A-producing antibody-secreting cell concentration in antibiotic-trea

168 9, 39, 278, and 233 for immunoglobulin (IgA) antibody-secreting cell counts; 401, 201, 533, and 284 f

169 mbers of bone marrow plasma cells and spleen antibody-secreting cells detected in the MN group.

170 that CD11c(+)Tbet(+) B cells were primed for antibody-secreting cell differentiation compared to rele

171 Functional characterization of antibody-secreting cell differentiation dynamics reveale

172 T. cruzi-specific antibody-secreting cells disappeared from the circulatio

173 Thus, antibody-secreting cells do not exclusively control the

174 munity as they differentiate into protective antibody-secreting cells during re-infection.

175 increases in the frequency of donor-specific antibody-secreting cells eight weeks after transplantati

176 charide (LPS)-specific immunoglobulin (Ig) A antibody-secreting cells (enzyme-linked immunospot [ELIS

177 logy for cellular infiltration, and measured antibody-secreting cells (enzyme-linked immunospot assay

178 ar activation correlated strongly with large antibody-secreting cell expansion and early production o

179 g but sustained production of virus-specific antibody-secreting cells for months.

180 moniae infection exaggerates early antiviral antibody-secreting cell formation, and at later times, l

181 sponding decrease in secondary high-affinity antibody-secreting cell formation.

182 differentiation, and spleen and bone marrow antibody-secreting cell frequencies were 10-fold higher

183 molecular to the clinical level, we isolated antibody-secreting cells from the cerebrospinal fluid of

184 were characterized and compared to those of antibody-secreting cells from untreated ITP spleens and

185 o evaluate the diversity of antigen-specific antibody-secreting cells generated during an in vivo hum

186 Antibody-secreting cells had increased I34 levels and we

187 nt stimulus resulted in normal generation of antibody-secreting cells, however the patient's T cells

188 Proliferative antibody-secreting cells, however, deviate from these gl

189 virus from the lung and enhanced humoral and antibody-secreting cell immune responses after 100% surv

190 imulated immunoglobulin A-producing anti-LPS antibody-secreting cells in 60, 91, and 100% of subjects

191 tence of Vi-specific IgG in serum and IgG(+) antibody-secreting cells in bone marrow.

192 uce protective CD8(+) T cells and long-lived antibody-secreting cells in CD4KO mice.

193 es of B cells, and numbers of virus-specific antibody-secreting cells in circulation of children hosp

194 ibody responses and in higher frequencies of antibody-secreting cells in corresponding draining cervi

195 selection and differentiation into activated antibody-secreting cells in mammalian germinal centers (

196 ), and the numbers of Campylobacter-specific antibody-secreting cells in peripheral blood failed to i

197 we revealed the infiltration of T cells and antibody-secreting cells in periventricular brain region

198 CCR9 can be expressed on IgM as well as IgA antibody-secreting cells in response to acute intestinal

199 MZ B cells rapidly differentiate into antibody-secreting cells in response to allotransplantat

200 Human B cells proliferate and turn into antibody-secreting cells in response to TLR3, TLR7 and T

201 i.n. immunization induced predominantly IgA antibody-secreting cells in salivary glands and IgA and

202 tibody levels and the number of HSV-specific antibody-secreting cells in secondary lymphoid tissues w

203 ollicles and differentiate into cytokine and antibody-secreting cells in T-independent and T-dependen

204 We enumerated donor-specific antibody-secreting cells in the blood of nine renal allo

205 We sought to quantify B-cell populations and antibody-secreting cells in the blood of patients with A

206 n lymph nodes, lungs and spleen, and boosted antibody-secreting cells in the bone marrow.

207 BALB/b mice had 25-fold more MHV-specific antibody-secreting cells in the central nervous system,

208 monoclonal antibodies (hMAbs) directly from antibody-secreting cells in the circulation of immunized

209 antly enhanced the number of AgI/II-specific antibody-secreting cells in the draining superficial cer

210 LPS in lung lavages and specific IgG and IgA antibody-secreting cells in the lungs and spleen.

211 ollicular helper (GC Tfh) and GC B cells and antibody-secreting cells in the spleen and bone marrow i

212 igen-specific immunoglobulin G (IgG) and IgA antibody-secreting cells in the spleen and draining lymp

213 and compare the dynamics of antigen-specific antibody-secreting cells in the spleen and kidney of pri

214 ing cells in salivary glands and IgA and IgG antibody-secreting cells in the superficial and central

215 raoral immunization also induced IgA and IgG antibody-secreting cells in the superficial and central

216 d virus-specific antibodies in the serum and antibody-secreting cells in their secondary lymphoid org

217 The frequency of antibody-secreting cells in tissues, postulated to funct

218 eting cells, including listeria-specific IgA antibody-secreting cells, in the lamina propria of the s

219 patients, and a 10-fold decrease in anti-DNA antibody-secreting cell lines was found after treatment

220 subcutaneous (neck) immunization induced IgG antibody-secreting cells mainly in the draining facial l

221 stribution and maintenance of these critical antibody-secreting cells may serve as potential therapeu

222 eutralizing antibodies, mucosal and systemic antibody-secreting cells, memory B cells, and gamma inte

223 oth total and RV-specific murine IgM and IgA antibody-secreting cells migrate efficiently to CCL28 (t

224 ells become activated and differentiate into antibody-secreting cells more rapidly than naive B cells

225 y lower measles-specific antibody levels and antibody-secreting cell numbers were also observed, indi

226 quality of antibody and coupled with reduced antibody-secreting cell numbers.

227 1, 3, and 4 showed a significant increase in antibody-secreting cells on ELISPOT.

228 rise from B220(+) memory B cells and produce antibody-secreting cells on rechallenge with antigen.

229 serum antibody responses (p < 0.05) and more antibody-secreting cells (p < 0.05).

230 nge with an average of 3253 IgA and 1227 IgG antibody-secreting cells per million peripheral blood mo

231 NV-specific memory B cells but not antibody-secreting cells persisted 180 days after infect

232 early to immune challenge and display a pre-antibody-secreting cell phenotype.

233 using a live virus neutralization assay, and antibody-secreting cell population frequencies were dete

234 gD(neg)CD27(neg)CD11c(+)CXCR5(neg) (DN2) pre-antibody secreting cell (pre-ASC) subset.

235 ts suggest strategies to remove xenoreactive antibody-secreting cells prior to transplantation.

236 Antibody-secreting cells producing antilipopolysaccharid

237 In these mice, antibody-secreting cells recognizing multivalent antigen

238 ti-BLyS treatment, yet the number of natural antibody-secreting cells remained constant.

239 Most vaccinees had an IgA antibody-secreting cell response against colonization fa

240 ix volunteers that received 10(4) CFU had an antibody-secreting cell response, and four had a serum I

241 ived 10(3) CFU excreted SC602 and had an IgA antibody-secreting cell response.

242 ling in the development of anti-WNV-specific antibody-secreting cell responses and memory B cell resp

243 Although many of the volunteers generated antibody-secreting cell responses to Vi, only 2 of the 3

244 Antibody-secreting cell responses were biased toward IgA

245 compared to rLBNSE, could differentiate into antibody-secreting cells, resulting in rapid and potent

246 lipopolysaccharide responses, as measured by antibody-secreting cell, serum, or fecal antibody levels

247 nduced similar frequencies of stalk-reactive antibody-secreting cells, showing that HA head immunodom

248 differentiation, which cooperate to generate antibody-secreting cells that cause the deposition of an

249 ic IgM(+) MBCs proliferated and gave rise to antibody-secreting cells that dominated the early second

250 The level of circulating antibody-secreting cells that make anti-galalpha1-3gal a

251 -cells to proliferate and differentiate into antibody-secreting cells that morphologically resemble p

252 en and induced B cells to differentiate into antibody-secreting cells that produced DSAs.

253 ant increase in the iliac lymph nodes of IgA antibody-secreting cells to p27 (P < 0.02), CD8-suppress

254 in these children differentiated quickly to antibody-secreting cells to the new vaccine antigens.

255 B lymphocytes differentiate into antibody-secreting cells under the antigen-specific cont

256 (anti-LGI1 mAb) derived from a patient's CSF antibody-secreting cell was infused intracerebroventricu

257 ver, in vitro differentiation of memBcs into antibody-secreting cells was 6.1-, 2.6-, and 3.7-fold si

258 The number of Ag-specific antibody-secreting cells was transiently reduced, but th

259 are required for B-cell differentiation into antibody-secreting cells, we found that MM cells inheren

260 In addition, specific antibody-secreting cells were detectable in the lamina p

261 oreover, robust circulating VP1-specific IgA antibody-secreting cells were detected 1 week postvaccin

262 Long-lived antibody-secreting cells were detected in the bone marro

263 F protein-specific antibody-secreting cells were detected in the bone marro

264 Circulating antibody-secreting cells were enumerated using enzyme-li

265 tantial populations of endemic HCoV-reactive antibody-secreting cells were identified and possessed h

266 were detected in lung lavages, and specific antibody-secreting cells were isolated from the spleen a

267 Antibody production and the frequency of antibody-secreting cells were significantly elevated in

268 in a dramatic reduction of antigen-specific antibody-secreting cells, whereas deletion of relb had n

269 f-HA causes a population of immunoglobulin G antibody-secreting cells, which dominate the primary res

270 (T(FH)) cells are CD4(+) T cells that select antibody secreting cells with high antigenic affinity in

271 ly polarized antibody repertoire in CD138(+) antibody-secreting cells within the PLN.