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1 nd humoral immune responses were assessed by anticapsular and antiprotein IgG concentrations.Measurem
2 Adults respond to NP carriage by mounting anticapsular and weak antiprotein antibody responses, an
3 t limiting doses, the polysaccharide-induced anticapsular antibodies also were less effective in conf
4 rmination of the binding of Fab fragments of anticapsular antibodies as a measure of matrix density;
5 order to assess if it is feasible to develop anticapsular antibodies as a potential novel therapy, it
8 isparities in the functional activity of the anticapsular antibodies elicited in adults by the two va
9 uate the effect of passive immunization with anticapsular antibodies on nasopharyngeal carriage, two
10 but it is not known whether vaccine-induced anticapsular antibodies that lack bactericidal activity
13 was associated with higher concentrations of anticapsular antibodies, but not all sera with anticapsu
15 ty is associated with higher-avidity group C anticapsular antibodies, which are present in concentrat
19 activity had a higher geometric mean group C anticapsular antibody concentration (0.72 microg/ml) tha
21 were assayed for serogroups C, W-135, and Y anticapsular antibody concentrations by use of a radioan
23 ccines elicit higher concentrations of serum anticapsular antibody in infants and children than do un
24 had no effect on bacteremia, whereas group C anticapsular antibody in sera from adults immunized with
25 of life, whereas maternal serotype-specific anticapsular antibody is associated with protection agai
27 ity functions as an important determinant of anticapsular antibody protective efficacy against pneumo
29 ncentrations of polysaccharide-induced serum anticapsular antibody to achieve 50% complement-mediated
33 group had up to 7-fold-higher geometric mean anticapsular-antibody titers than the alum group and 5-
35 apsular type by serological testing based on anticapsular antisera and by different WGS-based pipelin
39 t (i) there are multiple mechanisms by which anticapsular IgG MAbs facilitate phagocytosis of encapsu
43 f an anti-GNA33 mAb is similar to that of an anticapsular mAb but less active than an anti-P1.2 mAb.
45 g fluorophore-labeled polyclonal anti-C3 and anticapsular monoclonal antibodies and rosetting of fluo
47 ise studies that have investigated GBS serum anticapsular or anti-protein antibodies, and studies mea
48 phagocytic assay (OPA) and compared with IgG anticapsular polysaccharide antibody concentrations meas
50 odies to dams demonstrated conclusively that anticapsular polysaccharide IgG alone is sufficient for