ライフサイエンスコーパス: antiepileptic

1 ptic transmission, and their antagonists are antiepileptic.

2 ugs, selective calcium channel blockers, and antiepileptics.

3 embrane oxygenation, convulsions, and use of antiepileptics.

4 evaluate the potential of MAGL inhibitors as antiepileptics.

5 There is insufficient evidence for other antiepileptics.

6 000 subjects with different illnesses) of 11 antiepileptics.

7 promising candidates for development as new antiepileptics.

8 psy is common (~90%) and often refractory to antiepileptics.

9 restraints, and exposure to vasopressors and antiepileptics.

10 ially at the first DHR, followed by aromatic antiepileptics (7/25, 28.0%), vancomycin (4/25, 16.0%),

11 neficial in certain cases; for instance, the antiepileptic action of a high fat and low carbohydrate

12 To test whether NPY and galanin have antiepileptic actions in human epileptic tissue as well,

13 emizole binds to serotonin receptors and its antiepileptic activity can be mimicked by drugs acting o

14 ABHD6 blockade retained its antiepileptic activity over chronic dosing and was not a

15 f the neuronal cultures, suggesting possible antiepileptic activity.

16 th greater efficacy than currently available antiepileptics (AEDs).

17 uramine 0.7 mg/kg per day, added to existing antiepileptic agents for 14 weeks.

18 a small number of "high-risk" drugs such as antiepileptic agents, sulfonamides, and antiretroviral d

19 s, anxiolytics, antipsychotics, opioids, and antiepileptics among community-dwelling older adults wit

20 ures in mice and the effects thereon of some antiepileptic and anti-inflammatory treatments to establ

21 y prescribed medications, including lithium, antiepileptic and antipsychotic treatment showed signifi

22 blocking cerebellar AMPA receptors would be antiepileptic and devoid of motor impairment.

23 widely used culinary herb that also exhibits antiepileptic and other therapeutic activities, is a hig

24 leiotropy between intracranial aneurysms and antiepileptic and sex hormone drugs, providing insights

25 Moreover, antiepileptics and calcium channel blockers may provide

26 justment of antibiotics, immunosuppressives, antiepileptics, and other drugs, but its use for traditi

27 olides, quinolones, doxycycline, nonaromatic antiepileptics, and paracetamol were often tolerated.

28 xcitable cells, and they are key targets for antiepileptic, antiarrhythmic, and analgesic drugs.

29 f other diuretics, aspirin, antidepressants, antiepileptics, antihypertensives, or central nervous sy

30 uced colitis, while they were ineffective as antiepileptics at the same doses in control mice without

31 This is in contrast to other antiepileptic compounds that have previously been shown

32 , the current study is the first to describe antiepileptic drug (AED) combination therapy patterns ac

33 Antiepileptic drug (AED) exposure during pregnancy incre

34 xposure to maternal epilepsy with or without antiepileptic drug (AED) therapy and pregnancy and perin

35 rn exists that breastfeeding during maternal antiepileptic drug (AED) therapy may be harmful.

36 To investigate antiepileptic drug (AED)-related weight changes in patie

37 We analysed data from the Standard and New Antiepileptic Drug (arm B) study, a randomised trial tha

38 usual concomitant medications, including an antiepileptic drug (phenytoin or carbamazepine), dexamet

39 its application to the total synthesis of an antiepileptic drug (R)-lacosamide 2 are described.

40 amine recent studies of local anesthetic and antiepileptic drug binding to a sodium channel, revealin

41 The antiepileptic drug carbamazepine (CBZ) is one of the mos

42 In contrast, the antiepileptic drug carbamazepine was found to inhibit vo

43 Treatment options included antiepileptic drug changes, epilepsy surgery, and pacema

44 zure may afford improved treatments, such as antiepileptic drug chronotherapy, or timely warning to p

45 Clinical trials as part of antiepileptic drug development are increasingly expensiv

46 development cohort comprised 399 women whose antiepileptic drug doses were adjusted based on clinical

47 also could be relevant in reducing standard antiepileptic drug efficacy.

48 psy and undertook subgroup analysis based on antiepileptic drug exposure in women with epilepsy.

49 At 36 months, prenatal antiepileptic drug exposure was associated with adverse

50 The association of epilepsy and antiepileptic drug exposure with pregnancy outcomes need

51 The Equivalence Among Antiepileptic Drug Generic and Brand Products in People

52 ponse to the addition of a previously unused antiepileptic drug in a cohort of 155 people with refrac

53 lammation, valproic acid (VPA), an effective antiepileptic drug in this seizure model, mesalazine (MS

54 re also scanned after a blocking dose of the antiepileptic drug levetiracetam (20 mg/kg).

55 The antiepileptic drug levetiracetam (LEV) is a potential tr

56 50, and 150 mug/kg) or preblocking with the antiepileptic drug levetiracetam at 10 and 30 mg/kg.

57 urthermore, the addition of the SV2A-binding antiepileptic drug levetiracetam to the medium inhibited

58 ncluding an expedient total synthesis of the antiepileptic drug levetiracetam.

59 we enrolled pregnant women with epilepsy on antiepileptic drug monotherapy (carbamazepine, lamotrigi

60 Lamotrigine was selected as the antiepileptic drug of interest because of its wide use,

61 was applied to the "green" synthesis of the antiepileptic drug Phenytoin, with no use of any harmful

62 born to women enrolled in the North American Antiepileptic Drug Pregnancy Registry between 1997 and 2

63 Phenytoin was the most common antiepileptic drug prescribed de novo (61%).

64 hat they are important currently unexploited antiepileptic drug targets.

65 rovide an example of cross-over pharmacology antiepileptic drug testing.

66 Levetiracetam (LEV) is a prominent antiepileptic drug that binds to neuronal synaptic vesic

67 AZA is an antiepileptic drug that has been shown to inhibit AQP4 e

68 Retigabine (RTG) is a first-in-class antiepileptic drug that suppresses neuronal excitability

69 Third-line antiepileptic drug therapies with sedating or anesthetic

70 l seizures who do not respond to appropriate antiepileptic drug therapy consisting of 2 or more medic

71 Antiepileptic drug therapy, though beneficial for restra

72 rom immediate remission after taking a first antiepileptic drug to frequent unremitting seizures with

73 CSD was also decreased by the antiepileptic drug topiramate, but not by carbamazepine.

74 re the absence of a control group continuing antiepileptic drug treatment and a consistent definition

75 to treatment failure were treatment history (antiepileptic drug treatment prior to randomisation), EE

76 ergency that is typically terminated through antiepileptic drug treatment, leads to hippocampus dysfu

77 to breastfeed their children irrespective of antiepileptic drug treatment.

78 in children exposed, in utero, to different antiepileptic drug treatments.

79 of improvement is similar to that of recent antiepileptic drug trials in drug resistant epilepsy (DR

80 linear regression adjusted for maternal IQ, antiepileptic drug type, standardised dose, gestational

81 herapy were not different from those without antiepileptic drug use at both time points (PFS: HR, 0.9

82 combined analysis of survival association of antiepileptic drug use at the start of chemoradiotherapy

83 Stiripentol is an antiepileptic drug used to treat children affected by Dr

84 definite cause of pancreatitis is due to the antiepileptic drug valproic acid (VPA).

85 Current versus previous use of any antiepileptic drug was associated with an increased risk

86 During pregnancy, the dose of an antiepileptic drug was changed at least once in 74% of p

87 Carbamazepine (CBZ) is an antiepileptic drug which is persistent in wastewater tre

88 VPA is a commonly prescribed antiepileptic drug with known teratogenic effects.

89 With increasing age and treatment duration, antiepileptic drug withdrawal may be justified.

90 fore remission, seizure-free interval before antiepileptic drug withdrawal, age at onset of epilepsy,

91 fore remission, seizure-free interval before antiepileptic drug withdrawal, number of antiepileptic d

92 Cenobamate (YKP3089), an investigational antiepileptic drug, has shown broad-spectrum anticonvuls

93 The antiepileptic drug, levetiracetam, blocked Kv4.2 depleti

94 that exposing mouse brain capillaries to the antiepileptic drug, valproic acid (VPA; 5 muM), signific

95 Carbamazepine (CBZ) is a worldwide used antiepileptic drug, which is metabolized to a large exte

96 pilepsy of childbearing potential because of antiepileptic drug-related teratogenicity and hormonal i

97 Randomization was stratified by antiepileptic drug.

98 site for levetiracetam, a second generation antiepileptic drug.

99 improved with age for infants exposed to any antiepileptic drug.

100 I 1.00, 1.02) as did those who had used more antiepileptic drugs (1.05; 95% CI 1.01 to 1.09).

101 ilepticus etiologies included subtherapeutic antiepileptic drugs (43%), alcohol or other nonantiepile

102 30% of epilepsy patients receiving antiepileptic drugs (AEDs) are not fully controlled by t

103 Antiepileptic drugs (AEDs) are the only neurotherapeutic

104 The mechanisms by which antiepileptic drugs (AEDs) cause birth defects (BDs) are

105 Currently available antiepileptic drugs (AEDs) fail to control seizures in 3

106 Antiepileptic drugs (AEDs) have cognitive side effects t

107 pectrometry (LC-MS/MS) method to quantify 14 antiepileptic drugs (AEDs) in human serum.

108 xcitability and controlling its degree using antiepileptic drugs (AEDs) is of prime importance for cl

109 Therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is widely established for old

110 es join the chemical fragments of well-known antiepileptic drugs (AEDs) such as ethosuximide, levetir

111 To evaluate the effects of epilepsy and antiepileptic drugs (AEDs) used during pregnancy on feta

112 perspectives for the design and discovery of antiepileptic drugs (AEDs) with fewer side effects by fo

113 atients with Alzheimer's disease with select antiepileptic drugs (AEDs), in low doses, is usually wel

114 REVIEW: Despite the availability of many new antiepileptic drugs (AEDs), only around 50% of people wi

115 tly suffering with epilepsy are resistant to antiepileptic drugs (AEDs).

116 trials of topical agents (e.g., capsaicin), antiepileptic drugs (e.g., gabapentin), injection of oth

117 The Equivalence among Generic Antiepileptic Drugs (EQUIGEN) chronic-dose study was a r

118 0.2 mg/kg), and only two did not need rescue antiepileptic drugs (ie, met rescue criteria; one on 0.0

119 At age 6 months, infants of mothers using antiepileptic drugs (n = 223) had a higher risk of impai

120 with carbamazepine (n = 31), other aromatic antiepileptic drugs (n = 24), abacavir (n = 11), nevirap

121 icus episodes were treatment with third-line antiepileptic drugs (odds ratio, 12.08; 95% confidence i

122 (p=0.052) and a lower number of concomitant antiepileptic drugs (p=0.03).

123 ional anaesthetics (isoflurane, desflurane), antiepileptic drugs (topiramate, lacosamide, pregabalin,

124 5-0.99), treatment history (taking non-SANAD antiepileptic drugs [other than those listed above] vs t

125 egister, we identified all incident users of antiepileptic drugs aged 15 years or older in Denmark be

126 regarding critical drug interactions between antiepileptic drugs and antiretrovirals, but are also pr

127 ldren of women with epilepsy who did not use antiepileptic drugs and children of fathers with epileps

128 yndromes, show specific responses to certain antiepileptic drugs and differentiate between responder

129 that there may be drug interactions between antiepileptic drugs and hormonal therapies, which can pr

130 ted with incident epilepsy in the absence of antiepileptic drugs and in the absence of diagnosed psyc

131 s) with epilepsy who were taking concomitant antiepileptic drugs and not currently receiving lamotrig

132 ies compared with those exposed to the other antiepileptic drugs and on non-verbal and executive func

133 disrupted by long-term therapy with certain antiepileptic drugs and the antimicrobial agent rifampin

134 reports of significant interactions between antiepileptic drugs and the efficacy of human growth hor

135 eral visual field constriction of any of the antiepileptic drugs and the mechanisms that lead to thes

136 Older antiepileptic drugs are often prescribed at seizure pres

137 Are antiepileptic drugs associated with reduced pain intensi

138 Nineteen patients (45.2%) had withdrawn from antiepileptic drugs at least once; 12 of those (63.2%) h

139 d case-control study and defined exposure to antiepileptic drugs at the index date (ie, time of suici

140 n issued a warning regarding suicidality and antiepileptic drugs based on meta-analyses of 199 random

141 epilepsy, who were receiving stable doses of antiepileptic drugs before study entry, were enrolled in

142 ore antiepileptic drug withdrawal, number of antiepileptic drugs before withdrawal, female sex, famil

143 es of epilepsy and the metabolic activity of antiepileptic drugs can adversely affect hypothalamic an

144 a mechanism by which early life exposure to antiepileptic drugs can impact cognitive and behavioral

145 substantial evidence indicates that several antiepileptic drugs can increase thyroid hormone metabol

146 t, the availability of more than 20 approved antiepileptic drugs can reduce the incentive to enrol in

147 Use of multiple antiepileptic drugs compared with the reference group wa

148 The antiepileptic drugs currently available to treat mTLE ar

149 provide the first evidence that exposure to antiepileptic drugs during a sensitive postnatal period

150 Clinical Question: Is maternal use of antiepileptic drugs during pregnancy associated with maj

151 Exposure to antiepileptic drugs during pregnancy is associated with

152 eight patients who had been seizure-free on antiepileptic drugs for at least a year after 3 or more

153 al postoperative seizure outcomes and use of antiepileptic drugs for different brain lesions causing

154 Two patients who had received multiple antiepileptic drugs for several years presented with a b

155 fficacy of epilepsy surgery and use of newer antiepileptic drugs for the treatment of intractable epi

156 Although the number of available antiepileptic drugs has increased substantially during t

157 ular drugs, painkillers, contrast media, and antiepileptic drugs have been recorded well above thresh

158 tenuate mutant seizure activity; seven other antiepileptic drugs have no effect.

159 the risk of suicide following treatment with antiepileptic drugs identified in randomized trials is e

160 Although the effects of antiepileptic drugs in central hypothyroidism have not y

161 Mucocutaneous discoloration induced by antiepileptic drugs in general and ezogabine in particul

162 of more than 80% without the need for rescue antiepileptic drugs in more than 50% of infants.

163 Other antiepileptic drugs increase sex hormone-binding globuli

164 Switching between generic antiepileptic drugs is a highly debated issue that affec

165 suggest conventional sodium channel blocking antiepileptic drugs may worsen the disease, we predicted

166 pilepsy who became seizure-free while taking antiepileptic drugs might consider discontinuing their m

167 uicide and whether psychiatric disorders and antiepileptic drugs modify the risk of attempted suicide

168 Changes in doses of antiepileptic drugs occurred more frequently in pregnant

169 We aimed to assess effects of commonly used antiepileptic drugs on cognitive outcomes in children up

170 fects of traditional and recently introduced antiepileptic drugs on excitatory and inhibitory brain m

171 ailable for the effects of second-generation antiepileptic drugs on hypopituitarism treatment.

172 ortex and striatum and probed the effects of antiepileptic drugs on neural excitability and the effec

173 Exclusion of antiepileptic drugs prescribed before the index date did

174 caffold the chemical fragments of well-known antiepileptic drugs such as ethosuximide, levetiracetam,

175 report (p=0.03), a lower number of previous antiepileptic drugs taken (p=0.052) and a lower number o

176 Most antiepileptic drugs target neuronal mechanisms.

177 Although many clinically-approved antiepileptic drugs target voltage-gated persistent sodi

178 nces between splice variants are occluded by antiepileptic drugs that bind to and stabilize inactivat

179 We also compared changes in the doses of antiepileptic drugs that were administered in the two gr

180 defined as failure of adequate trials of two antiepileptic drugs to achieve sustained seizure freedom

181 The effects of the antiepileptic drugs used in the MESS study are greater f

182 Use of antiepileptic drugs was associated with an increased ris

183 Prenatal exposure to antiepileptic drugs was associated with impaired fine mo

184 ous breastfeeding in children of women using antiepileptic drugs was associated with less impaired de

185 ional risk of suicide associated with use of antiepileptic drugs was generally low and should be bala

186 Bottom Line: Certain antiepileptic drugs were associated with increased rates

187 Antiepileptic drugs were categorized by MOA: sodium chan

188 andomised controlled trial in which standard antiepileptic drugs were compared with new treatments.

189 Additionally, six epilepsy patients on other antiepileptic drugs were examined five times with SKP as

190 antile epilepsies (<3 months), whereas other antiepileptic drugs were less effective.

191 ndations include the following: prophylactic antiepileptic drugs were not recommended for routine use

192 tive function (r=-0.42, p=0.0004), but other antiepileptic drugs were not.

193 th focal seizures despite treatment with 1-3 antiepileptic drugs were randomly assigned (1:1:1:1) via

194 ne phase) receiving one to three concomitant antiepileptic drugs were recruited from 99 centres acros

195 ften fatal syndrome, initially responsive to antiepileptic drugs which over time becomes refractory a

196 spiny neurons from neonatal rats exposed to antiepileptic drugs with proapoptotic action (phenobarbi

197 tients; however, data for the interaction of antiepileptic drugs with the pituitary axis have shown t

198 ants, drugs used in addictive disorders, and antiepileptic drugs) after prison release.

199 erization of drugs that modulate SV2A (e.g., antiepileptic drugs) and potentially could be a biomarke

200 Despite the availability of numerous antiepileptic drugs, 20-30% of epileptic patients are ph

201 ificant association of epilepsy, exposure to antiepileptic drugs, and adverse outcomes exists in preg

202 ubstrates including several antidepressants, antiepileptic drugs, and neuroleptics, which exert centr

203 Many women of childbearing potential take antiepileptic drugs, but the cognitive effects of fetal

204 seizures despite treatment with at least two antiepileptic drugs, eight patients who had been seizure

205 iconvulsants are of considerable interest as antiepileptic drugs, especially because of their potenti

206 g patients discharged with a prescription of antiepileptic drugs, phenytoin and levetiracetam were pr

207 and be influenced by seizure mechanisms and antiepileptic drugs, presenting unique management challe

208 y 30% of epilepsy patients do not respond to antiepileptic drugs, representing an unmet medical need.

209 e and are often resistant to treatments with antiepileptic drugs, such as carbamazepine and phenytoin

210 ary axis have shown that chronic use of many antiepileptic drugs, such as carbamazepine, oxcarbazepin

211 Phenytoin, one of the most widely used antiepileptic drugs, suppresses the abnormal brain activ

212 need for a thyroxine dose increase with some antiepileptic drugs, the effect of excessive thyroxine i

213 n part be attributed to the use of GABAergic antiepileptic drugs, the stability in glutamine across p

214 ntrolled despite the availability of over 20 antiepileptic drugs.

215 relation to seizure burden and control with antiepileptic drugs.

216 uctive outcomes, with or without exposure to antiepileptic drugs.

217 uction of cortical network interactions with antiepileptic drugs.

218 patients (62%) were in remission, 5 without antiepileptic drugs.

219 and is blocked by prior ingestion of typical antiepileptic drugs.

220 many local anesthetics, antiarrhythmics, and antiepileptic drugs.

221 eizure per month and failure of at least two antiepileptic drugs.

222 ts with IGE and PGTCS taking 1-3 concomitant antiepileptic drugs.

223 tic effects that alter the concentrations of antiepileptic drugs.

224 of exploration for the development of novel antiepileptic drugs.

225 ce by reducing target-site concentrations of antiepileptic drugs.

226 ve been associated with a worse tolerance of antiepileptic drugs.

227 ssociated with the mode of action of several antiepileptic drugs.

228 rebral lateralisation induced by exposure to antiepileptic drugs.

229 vasopressors, and treatment with third-line antiepileptic drugs.

230 g NMDA receptors being potential targets for antiepileptic drugs.

231 isk associated with the 9 most commonly used antiepileptic drugs.

232 sistant epilepsy that cannot be treated with antiepileptic drugs.

233 6 weeks postpartum in women with epilepsy on antiepileptic drugs.

234 en severe and resistant towards conventional antiepileptic drugs.

235 gnant women with epilepsy who are prescribed antiepileptic drugs.

236 may be considered for the development of new antiepileptic drugs.

237 suicide in current versus previous users of antiepileptic drugs.

238 d in people with epilepsy taking concomitant antiepileptic drugs.

239 o not achieve adequate seizure control using antiepileptic drugs.

240 e seizure-free and had started withdrawal of antiepileptic drugs; articles also had to contain inform

241 ormity of the cortical response and the cDCS antiepileptic effect.

242 that intestinal inflammation may reduce the antiepileptic effects of VPA, although we confirm that i

243 tified (>30%) have published evidence of the antiepileptic efficacy (for example, curcumin) or antiep

244 , GBR successfully identifies compounds with antiepileptic efficacy in animal models and, hence, it i

245 ched with drugs having published evidence of antiepileptic efficacy in animal models than expected by

246 y, in DSS-treated mice, VPA lost part of its antiepileptic efficacy in comparison to preventing seizu

247 abase as either having published evidence of antiepileptic efficacy or lacking such evidence, we demo

248 be utilized to provide proof of concept for antiepileptic efficacy with reduced motor side effects i

249 Other therapeutic classes, like antiepileptics, hypertensives, and gastric and ulcer dru

250 s been identified as the binding site of the antiepileptic levetiracetam (LEV), making it an interest

251 interpretation, treatment with the atypical antiepileptic levetiracetam at a low dose shown previous

252 onsteroidal antiinflammatories, antiseptics, antiepileptics, lipid regulators, beta-blockers and horm

253 Additionally, antiepileptic maneuvers may act as immunomodulators and

254 the possibility to detect carbamazepine, an antiepileptic massively prescribed and persistent in wat

255 Antiepileptics may significantly decrease opioid require

256 Of these, 17 (11.0%) remained on antiepileptic medication (AED).

257 independent of whether the patient underwent antiepileptic medication reduction.

258 the electrical detection of phenytoin as an antiepileptic medication with a narrow therapeutic dosag

259 diagnosis of epilepsy, a carefully selected antiepileptic medication with consideration of comorbidi

260 % receiving immunotherapy, and 58% receiving antiepileptic medication.

261 ow therapeutic range, and is a commonly used antiepileptic medication.

262 and intensity of monitoring, and changes in antiepileptic medication.

263 80; 95% CI, 1.73-8.33; P < .001), the use of antiepileptic medications (OR, 3.24; 95% CI, 1.31-8.00;

264 f treatment goals, use of corticosteroids or antiepileptic medications is helpful in symptomatic pati

265 s Treatment Trial), compare effectiveness of antiepileptic medications, and rigorous examination of e

266 izures had proven refractory to conventional antiepileptic medications, the sensitivity of mutant NMD

267 For women of childbearing potential who use antiepileptic medications, these findings must be balanc

268 m (EEG) readings, and treatment responses to antiepileptic medications.

269 ed, requiring long-term immunotherapy and/or antiepileptic medications.

270 omised controlled trial in patients starting antiepileptic monotherapy.

271 Reported etiology was antibiotic (n = 19), antiepileptic (n = 9), antipyretic (n = 9), other (n = 3

272 e presence of recent new drug treatment with antiepileptics or allopurinol, respectively.

273 Antiepileptics (OR = 1.20, p = 0.60) did not affect seiz

274 The antiepileptic pregabalin (Lyrica) shows clinical promise

275 ion, only ALAC and NaB exhibited significant antiepileptic properties in mice with induced colitis, w

276 Here, we investigate the antiepileptic properties of ranolazine exhibited through

277 p home despite continued compliance with her antiepileptic regimen.

278 ing periods when participants were receiving antiepileptics relative to periods when they were not (h

279 idence of an opposing endogenous homeostatic antiepileptic response.

280 ostasis in pyramidal cells could be a viable antiepileptic strategy.

281 that ABHD6 inhibition may represent a novel antiepileptic strategy.

282 ntestinal inflammation may represent a valid antiepileptic target which should also be considered as

283 throughout the brain and represent promising antiepileptic targets.

284 ted cognitive decline and might benefit from antiepileptic therapies.

285 g DS, and offer a platform for screening new antiepileptic therapies.

286 pilepsy is critical for developing effective antiepileptic therapies.

287 dard of aggressive therapy with conventional antiepileptic therapy in favor of early limitation of ca

288 To assess the response to antiepileptic therapy, we retrospectively reviewed the t

289 th regard to timing, dosing, and sequence of antiepileptic therapy.

290 an increase in use (from 2-fold increase for antiepileptics to 13-fold for hypertensives).

291 N: The data show that the BBB is a target of antiepileptic treatment and, more specifically, provide

292 ed to compare preventive versus conventional antiepileptic treatment in TSC infants.

293 Antiepileptic treatment of brain tumor patients mainly d

294 Recently, the concept of preventive antiepileptic treatment to modify the natural history of

295 out 60% of patients with epilepsy receive no antiepileptic treatment, largely for economic and social

296 d received vigabatrin either as conventional antiepileptic treatment, started after the first electro

297 per day or placebo, in addition to standard antiepileptic treatment.

298 Of the most commonly prescribed antiepileptics, treatment outcomes appeared to be better

299 In contrast, antidepressants and antiepileptics were not significantly associated with vi

300 od candidates for development as new, potent antiepileptics with a potential in benzodiazepine-resist