ライフサイエンスコーパス: antimicrobial agent

1 novel immunomodulating agent rather than an antimicrobial agent.

2 safe and effective use of ZnPT as a topical antimicrobial agent.

3 st active compound was lomofungin, a natural antimicrobial agent.

4 s (AgNPs) into base materials to serve as an antimicrobial agent.

5 te blood cell count, and be started on a new antimicrobial agent.

6 ed to the films in order to act as a natural antimicrobial agent.

7 aditional understanding of honey function as antimicrobial agent.

8 demonstrate this material to be an efficient antimicrobial agent.

9 nd biosynthesis of this clinically important antimicrobial agent.

10 d, copper (Cu) is attracting attention as an antimicrobial agent.

11 ntified reuterin to be the precursor-induced antimicrobial agent.

12 it a remarkably efficient optically mediated antimicrobial agent.

13 nion to generate hypochlorous acid, a potent antimicrobial agent.

14 e was the most frequently prescribed (24.6%) antimicrobial agent.

15 idone-iodine (PVI) is principally used as an antimicrobial agent.

16 ux is the best construct for testing various antimicrobial agents.

17 een on the rise due to the widespread use of antimicrobial agents.

18 hnology for multiple applications, including antimicrobial agents.

19 lity testing for less commonly used or newer antimicrobial agents.

20 e represent an avenue for development of new antimicrobial agents.

21 mpact the sensitivity of bacteria to various antimicrobial agents.

22 tegy that would allow recycling of substrate antimicrobial agents.

23 ng future design of more potent and specific antimicrobial agents.

24 ocidal activity of an underutilized class of antimicrobial agents.

25 ms demonstrate a decreased susceptibility to antimicrobial agents.

26 ntives for pharmaceutical development of new antimicrobial agents.

27 important for survival following exposure to antimicrobial agents.

28 t and disrupt bacterial membranes, acting as antimicrobial agents.

29 these drugs could lead to novel, broad range antimicrobial agents.

30 can be exploited to design disease-specific antimicrobial agents.

31 ments and contributing to resistance against antimicrobial agents.

32 promising target for the development of new antimicrobial agents.

33 erapeutic CO delivery in animals, are potent antimicrobial agents.

34 and P. aeruginosa were susceptible to fewer antimicrobial agents.

35 nisms to avoid being killed by commonly used antimicrobial agents.

36 tested that showed resistance to a class of antimicrobial agents.

37 of these 4-oxazolidinone natural products as antimicrobial agents.

38 fer potential insight into targets for novel antimicrobial agents.

39 analogues identified by previous studies as antimicrobial agents.

40 contribute in identifying novel targets for antimicrobial agents.

41 on therapy to augment the effects of current antimicrobial agents.

42 cline, doxycycline, and other broad-spectrum antimicrobial agents.

43 s designed to improve the appropriate use of antimicrobial agents.

44 rves as a barrier against the penetration of antimicrobial agents.

45 uple regimens in areas of high resistance to antimicrobial agents.

46 ould be an effective strategy to develop new antimicrobial agents.

47 biofilms is their extraordinary tolerance to antimicrobial agents.

48 mammalian cells and are inaccessible to many antimicrobial agents.

49 directions for the design of next-generation antimicrobial agents.

50 rial cell envelope can enhance resistance to antimicrobial agents.

51 uginosa biofilms and to resist the action of antimicrobial agents.

52 ynthesis of highly specific enantioselective antimicrobial agents.

53 application in hypertension, cancer, and as antimicrobial agents.

54 nts were initially treated with intravitreal antimicrobial agents.

55 included evidence of treatment with specific antimicrobial agents.

56 prevention practices and appropriate use of antimicrobial agents.

57 and recalcitrance to killing by microbicidal antimicrobial agents.

58 I, is an attractive target for the design of antimicrobial agents.

59 regulatory mechanism to resist the action of antimicrobial agents.

60 esigned with the aim to obtain potential new antimicrobial agents.

61 the design of lipidated gamma-AApeptides as antimicrobial agents.

62 for the development of potent broad-spectrum antimicrobial agents.

63 rance of biofilms to killing by microbicidal antimicrobial agents.

64 ntal treatment, and 1 month after the use of antimicrobial agents.

65 k of biofilms is their profound tolerance of antimicrobial agents.

66 he development of novel and highly selective antimicrobial agents.

67 biofilms, which render it more resistant to antimicrobial agents.

68 inhibitor development that could lead to new antimicrobial agents.

69 c interest because it mediates the action of antimicrobial agents.

70 or further development of TrmD inhibitors as antimicrobial agents.

71 t following treatment with several different antimicrobial agents.

72 and survival in the presence and absence of antimicrobial agents.

73 mutant was sensitive to a broad spectrum of antimicrobial agents.

74 fections, including those resistant to other antimicrobial agents.

75 o the effectiveness of the drugs to serve as antimicrobial agents.

76 gdunensis are susceptible to narrow-spectrum antimicrobial agents.

77 pecies: sanitation, nutrition, vaccines, and antimicrobial agents.

78 a concomitant increase in the need for novel antimicrobial agents.

79 omycin, clindamycin, tetracycline, and other antimicrobial agents.

80 f bacteria embedded in a biofilm to existing antimicrobial agents.

81 anisms that exhibited resistance to multiple antimicrobial agents.

82 ated with their ability to release long-term antimicrobial agents.

83 bials) or an alternative topical or systemic antimicrobial agent?

84 elopment do biofilms gain their tolerance to antimicrobial agents?

85 markedly enhancing bacterial killing by the antimicrobial agent (3-log increase versus antimicrobial

86 49.7%-52.3%) patients were on 3611 systemic antimicrobial agents; 462 (12.8%) were prescribed for su

87 tency </=7 days were caused predominantly by antimicrobial agents (71%).

88 rance of biofilms to killing by bactericidal antimicrobial agents, a phenotype comparable to that obs

89 noparticles to carry and selectively release antimicrobial agents after attachment or within oral bio

90 acid (CA) has been suggested as an effective antimicrobial agent against biofilms formed on titanium.

91 he RBC-nanogel system as a new and effective antimicrobial agent against MRSA infection.

92 Pentamidine is an effective antimicrobial agent against several human pathogens, but

93 ion performed better than bulk extract as an antimicrobial agent against some foodborne pathogenic ba

94 ties of gallium maltolate (GaM) and 20 other antimicrobial agents against clinical equine isolates of

95 These findings uncover the role of siRNAs as antimicrobial agents against eukaryotic pathogens and hi

96 nce suggests that sRNAs can also function as antimicrobial agents against nonviral pathogens and dire

97 ated the activity of ceftaroline and various antimicrobial agents against S. aureus isolates accordin

98 structural basis for the development of new antimicrobial agents against this family of bacterial 2-

99 Broad-spectrum antimicrobial agents also increase the risk of developin

100 rase as a valid target for the design of new antimicrobial agents among Gram-positive pathogens.

101 d to monitor susceptibility to commonly used antimicrobial agents among important pathogens.

102 undant host metabolite thought to be both an antimicrobial agent and a modulator of the host inflamma

103 the innate immune system may use zinc as an antimicrobial agent and that zinc efflux is an important

104 Despite the use of appropriate antimicrobial agents and advanced supportive care, the m

105 als for the smart and controlled delivery of antimicrobial agents and aims at identifying the advanta

106 insecticides; documentation of links between antimicrobial agents and alterations in hormone response

107 hat soluble factors including AMPs are hCVAM antimicrobial agents and are consistent with a role for

108 ride (LPS), thereby increasing resistance to antimicrobial agents and avoidance of the host immune sy

109 ance because they decrease susceptibility to antimicrobial agents and enhance the spread of antimicro

110 render various organisms less susceptible to antimicrobial agents and environmental stresses.

111 highly increases the bacterial resistance to antimicrobial agents and host immune clearance.

112 state is considered to be more vulnerable to antimicrobial agents and immune responses, dispersion is

113 per describes the development and use of new antimicrobial agents and immune-based and host-directed

114 infections, such as combinations of various antimicrobial agents and intravenous immunoglobulin (IVI

115 design principles toward the development of antimicrobial agents and materials.

116 terococcal cell membrane response to diverse antimicrobial agents and peptides; as such, LiaR represe

117 Modified use of antimicrobial agents and public health interventions, co

118 e species and have promising applications as antimicrobial agents and scaffolds for peptide drugs.

119 gram-negative bacteria to resist killing by antimicrobial agents and to avoid detection by host immu

120 rade water preserved with sodium omadine, an antimicrobial agent, and sodium thiosulfate, a dechlorin

121 for congenital blistering diseases and as an antimicrobial agent, and we discuss limitations and futu

122 medicinal herbs, which are known to contain antimicrobial agents, and are rich in different active s

123 utamicum cultured in the presence of certain antimicrobial agents, and elucidation of this system exp

124 is highly sensitive to oxidants and several antimicrobial agents, and exhibits diminished intramacro

125 treatment (intensive care, a combination of antimicrobial agents, and nutritional support, with or w

126 tained low-efficiency dialysis, antibiotics, antimicrobial agents, and pharmacokinetics.

127 hospital resources, absence of available new antimicrobial agents, and potential lack of reimbursemen

128 nizes and actively extrudes a broad range of antimicrobial agents, and promotes the intrinsic resista

129 sts can aid the development of sorely needed antimicrobial agents, and the study of antimicrobial age

130 ge in average monthly antimicrobial use (all antimicrobial agents, anti-methicillin-resistant Staphyl

131 ge in average monthly antimicrobial use [all antimicrobial agents, anti-methicillin-resistant Staphyl

132 Resistance of invasive NTS to first-line antimicrobial agents appeared to be stable in England, b

133 nabsorbed macrocyclic compound, is the first antimicrobial agent approved by the FDA for the treatmen

134 To fight against AMR bacteria, new antimicrobial agents are continually needed, and their e

135 New antimicrobial agents are greatly needed to treat infecti

136 MICs to most antimicrobial agents are relatively low.

137 Moreover, this class of antimicrobial agents are resistant to proteolytic degrad

138 al pathogenesis has become so great that new antimicrobial agents are tested for their capacity of ta

139 thway is a target for the development of new antimicrobial agents as it is essential for microorganis

140 d DeltasagS biofilm cells as recalcitrant to antimicrobial agents as wild-type biofilms, likely by re

141 rane is therefore critical to developing new antimicrobial agents, as this membrane makes direct cont

142 Is treatment with topical or systemic antimicrobial agents associated with better venous leg u

143 ration (2.29 [1.22-4.29]), and not receiving antimicrobial agents at day 1 (3.56 [1.94-6.53]) were id

144 ia and determination of their sensitivity to antimicrobial agents at the single-cell level.

145 e-NO hybrids represent the first dual-action antimicrobial agent based on the baterial QS inhibition

146 We have developed a class of selective antimicrobial agents based on the recognition of the sha

147 Administering antimicrobial agents before obtaining blood cultures cou

148 ontribute to the development of vaccines and antimicrobial agents, but they have focused chiefly on v

149 rtnerships as well as the discovery of novel antimicrobial agents by enabling the rapid identificatio

150 complex structure enhances the resistance to antimicrobial agents by limiting the transport of active

151 The emergence of resistance to multiple antimicrobial agents by pathogenic bacteria has become a

152 eeded antimicrobial agents, and the study of antimicrobial agents can help immunologists discover tar

153 ll patients with the broad-spectrum, topical antimicrobial agent chlorhexidine is widely performed an

154 Green tea extract is a naturally occurring antimicrobial agent, consisting of polyphenols (catechin

155 tic tissue culture and sonication culture of antimicrobial agent-containing cement spacers (ACSs) col

156 ections are readily curable with appropriate antimicrobial agents; cryptosporidiosis and C. difficile

157 Pharmacokinetics/pharmacodynamics of antimicrobial agents, differences among bacterial specie

158 r of days an infant was exposed to 1 or more antimicrobial agents divided by the total length of hosp

159 aminated procedures, additional prophylactic antimicrobial agent doses should not be administered aft

160 icrobial strains and their interactions with antimicrobial agents, e.g., the Kirby-Bauer susceptibili

161 to increased resistance of this bacterium to antimicrobial agents, especially Clarithromycin.

162 a were interrogated by heat, filtration, and antimicrobial agents, followed by limiting dilution tran

163 al of WR12 and D-IK8 to be used as a topical antimicrobial agent for the treatment of staphylococcal

164 s, micro-organisms to identify fungitoxic or antimicrobial agents for controlling serious plant patho

165 une stimuli currently under investigation as antimicrobial agents for different species.

166 oxidants and also in food industry as strong antimicrobial agents for food preservation.

167 apid selection and distribution of effective antimicrobial agents for treatment and postexposure prop

168 e garnered renewed interest for their use as antimicrobial agents, for instance, in the treatment of

169 Triclosan (TCS) and triclocarban (TCC) are antimicrobial agents formulated in a wide variety of con

170 l, and bis(5-chloro-2-hydroxyphenyl)methane) antimicrobial agents found in biosolids were analyzed.

171 flux pumps, which expel proteins, toxins and antimicrobial agents from Gram-negative bacteria.

172 Escherichia coli extruding a vast variety of antimicrobial agents from the cell.

173 s, to data on infectious diseases and use of antimicrobial agents from the National Patient Register

174 used to tailor the delivery of combinatorial antimicrobial agents from various metallic implantable d

175 The local delivery of antimicrobial agents has demonstrated benefit in mild to

176 anoparticles (AgNPs) in consumer products as antimicrobial agents has prompted extensive research tow

177 Progressive resistance to antimicrobial agents has reduced options for gonorrhea t

178 ated with drug-resistant pathogens, and many antimicrobial agents have adverse effects restricting th

179 ent of novel but still conventional systemic antimicrobial agents, having only a single mode or site

180 PBGS modulators for potential application as antimicrobial agents, herbicides, or drugs for porphyric

181 First proposed as antimicrobial agents, histones were later recognized for

182 e of highly efficacious interventions (e.g., antimicrobial agents, HIV treatment) which are not adequ

183 nce of highly efficacious interventions (eg, antimicrobial agents, human immunodeficiency virus treat

184 approved regimen that includes an additional antimicrobial agent (ie, CRO 250 mg, intramuscular singl

185 Based on this analysis, copper use as an antimicrobial agent in algae resistant shingles and trea

186 Copper is used as an antimicrobial agent in building materials such as algae-

187 ers via wastewater effluents, triclosan, the antimicrobial agent in handsoaps, and chlorinated triclo

188 r 5-aminolevulinic acid, which is used as an antimicrobial agent in photodynamic therapy, potentiates

189 regulatory mechanism to resist the action of antimicrobial agents in a BrlR-dependent manner which af

190 ractive targets for the development of novel antimicrobial agents in a time of rising antibiotic resi

191 In contrast, the effect of antimicrobial agents in adopted immunity, although funda

192 number of studies suggest that both of these antimicrobial agents in combination are more effective i

193 bination treatment with SWCNTs and oxidizing antimicrobial agents in developing highly effective spor

194 NO2(-) and Cl(-) as they serve as important antimicrobial agents in meat to inhibit the growth of ba

195 eberry proanthocyanidins are the most potent antimicrobial agents in the fruit.

196 shown to help reduce the use of unnecessary antimicrobial agents in the hospital setting.

197 with the downturn in the development of new antimicrobial agents in the pharmaceutical industry pose

198 remain some of the more commonly prescribed antimicrobial agents in the United States, despite the w

199 is a pressing need for novel narrow-spectrum antimicrobial agents in veterinary medicine.

200 The patient received courses of several antimicrobial agents, including linezolid for 79 days.

201 es in bacterial susceptibility to a panel of antimicrobial agents, including tigecycline.

202 aces creating biofilms that are resistant to antimicrobial agents, increasing mortality and morbidity

203 t increases in synergy between AZM and other antimicrobial agents, indicating that dysregulation of t

204 antimicrobial film and the diffusion of the antimicrobial agent into the food.

205 aluated the benefits of local application of antimicrobial agents into ERC contrast media in preventi

206 chanisms could be harnessed to deliver other antimicrobial agents into Gram-negative bacteria.

207 Effective delivery and accumulation of antimicrobial agents into the microbial organism is esse

208 of new antibiotics or localised delivery of antimicrobial agents, iron sequestration, inhibition of

209 No antimicrobial agent is clearly superior for the initial

210 Before a new antimicrobial agent is used to treat infections, it must

211 The decreasing effectiveness of antimicrobial agents is a growing global public health c

212 ws that design of target-specific veterinary antimicrobial agents is possible, even species within a

213 has recently been repurposed as a potential antimicrobial agent; it performed well against many Gram

214 Pseudomonas aeruginosa biofilm tolerance to antimicrobial agents known as multidrug efflux pump subs

215 ield after 24 h, a valuable precursor of the antimicrobial agent Levofloxacin.

216 1,4]oxazine, which is a key precursor of the antimicrobial agent Levofloxacin.

217 its that have been successfully developed as antimicrobial agents, lung surfactant replacements, enzy

218 pe tested, led to enhanced resistance to the antimicrobial agent lysozyme.

219 imely management with the appropriate use of antimicrobial agents may optimize visual outcomes.

220 In contrast to growth-based antimicrobial agents, membrane-targeting drugs effective

221 Although antimicrobial agent-modified dental restoration systems

222 mal inhibitory concentrations (MICs) of four antimicrobial agents, namely, cefazolin, ceftazidime, ce

223 Lincomycin A is a potent antimicrobial agent noted for its unusual C1 methylmerca

224 ing by BrlR, and recalcitrance to killing by antimicrobial agents of DeltasagS biofilm cells.

225 Because antimicrobial agents of different classes and varying ac

226 mechanism of resistance to host defenses and antimicrobial agents of diverse classes.

227 r species bacteremia and received at least 1 antimicrobial agent, of whom 52 (14%) died during hospit

228 l cellulitis, and to look for the effects of antimicrobial agents on these biofilms by colorimetric a

229 ntibiotherapy; escalation (addition of a new antimicrobial agent or change in antibiotic to one with

230 ur groups: de-escalation (interruption of an antimicrobial agent or change of antibiotic to one with

231 be managed conservatively with prophylactic antimicrobial agents or curatively with hematopoietic st

232 cially available FDA-cleared tests for newer antimicrobial agents or for older agents with updated br

233 fied as fully susceptible, resistant to >/=1 antimicrobial agent, or resistant to a first-line agent.

234 his protein family, extrudes a wide range of antimicrobial agents out of bacteria.

235 resistance that results in the extrusion of antimicrobial agents outside the bacterial cell.

236 Resistance to fluoroquinolone antimicrobial agents, particularly ciprofloxacin, has in

237 he risk associated with inappropriate use of antimicrobial agents, patients with suspected sepsis mus

238 susceptibility testing for 12 commonly used antimicrobial agents (penicillin, methicillin, erythromy

239 4 weeks of treatment with two or more active antimicrobial agents, plus removal of the intravascular

240 ignificance of S. lugdunensis isolation, the antimicrobial agents prescribed, if any, and the clinica

241 Triclosan is a frequently detected and toxic antimicrobial agent present in many consumer and industr

242 Initial trials with six antimicrobial agents produced incorrect susceptibility c

243 Helicobacter pylori have become resistant to antimicrobial agents, reducing eradication rates.

244 Active packaging foils with incorporated antimicrobial agents release the active ingredient durin

245 The development of antimicrobial agents represents one of the most signific

246 Pseudomonas aeruginosa, biofilm tolerance to antimicrobial agents requires the biofilm-specific MerR-

247 A large number of available antimicrobial agents retain very good in vitro activity

248 apy with certain antiepileptic drugs and the antimicrobial agent rifampin, resulting in drug-induced

249 rsenicals such as the trivalent forms of the antimicrobial agents roxarsone (Rox(III)), nitarsone (Ni

250 Antimicrobial agents secreted into urine potentially pla

251 Treatment of shigellosis with appropriate antimicrobial agents shortens duration of illness and ba

252 Topical antimicrobial agents should not be applied to the surgic

253 een intensified due to their high content of antimicrobial agents such as polyphenols, i.e. flavonoid

254 Two antimicrobial agents such as surfactin and Herbmedotcin

255 ling a controlled and slow release of active antimicrobial agents, such as essential oils (EO).

256 mended to detect resistance to commonly used antimicrobial agents; such testing is complicated by dif

257 offer insight into the development of novel antimicrobial agents targeting the dimeric antibiotic ta

258 Triclosan is a widespread antimicrobial agent that accumulates in anaerobic digest

259 Transferrin is a promising, novel antimicrobial agent that merits clinical investigation.

260 c enzymes, providing an example of a natural antimicrobial agent that specifically targets glycolysis

261 GML is a potent antimicrobial agent that targets a range of bacteria, fu

262 des (ADEPs) represent an attractive class of antimicrobial agents that act through dysregulation of c

263 These host cells contain and produce many antimicrobial agents that are effective at killing bacte

264 anism by which bacteria evade the effects of antimicrobial agents that are substrates.

265 ntarium of pattern recognition molecules and antimicrobial agents that identify and eliminate pathoge

266 Antimicrobial agents that inhibit protein synthesis such

267 ts it as an attractive target for developing antimicrobial agents that interfere specifically with la

268 iofilms is their extraordinary resistance to antimicrobial agents that is activated during early biof

269 is a viable strategy for the development of antimicrobial agents that target bacterial pathogens.

270 research is currently focused on developing antimicrobial agents that target lipid II, a vital precu

271 ith the purpose of developing broad spectrum antimicrobial agents that target the substrate and nucle

272 the minimum inhibitory concentration of ten antimicrobial agents, the sporulation efficiency and the

273 underlined the importance of developing new antimicrobial agents to combat such infections.

274 rove valuable for the design of new types of antimicrobial agents to combat the emergence of antibiot

275 een growing interest in the discovery of new antimicrobial agents to increase safety and shelf-life o

276 and the feasibility of using NPs to deliver antimicrobial agents to treat a cutaneous pathogen.

277 Clinicians have been resorting to older antimicrobial agents to treat infections caused by MDR A

278 The use of nontherapeutic broad-spectrum antimicrobial agents triclosan (TCS) and benzalkonium ch

279 microbial consortia, rather than individual antimicrobial agents, underlie the observed reductions i

280 rfaces releasing chlorhexidine, a well-known antimicrobial agent used in mouthwash products and antis

281 otentiates the activity of metronidazole, an antimicrobial agent used in the treatment of bacterial v

282 cin disaccharide to provide even more potent antimicrobial agents [VRE minimum inhibitory concentrati

283 Biofilm formation and resistance to antimicrobial agents was also observed in several clades

284 In the present study, nisin, an antimicrobial agent, was encapsulated in essential oil-c

285 Targeted antimicrobial agents were administered, and the patient

286 Antimicrobial agents were cited as most effective but we

287 robial susceptibility tests against thirteen antimicrobial agents were determined using the K-B diffu

288 In total, 25 antimicrobial agents were examined.

289 hydrolysates were found to act as potential antimicrobial agents when incubated with E. coli and Bac

290 Sulfonamides are antimicrobial agents widely employed in animal productio

291 DR) Enterobacterales on the rise, a nontoxic antimicrobial agent with a unique mechanism of action su

292 Aztreonam-avibactam is a combination antimicrobial agent with activity against carbapenemase-

293 Fidaxomicin (FDX) is a novel antimicrobial agent with narrow-spectrum and potent bact

294 PCMC (4-chloro-m-cresol), household derived antimicrobial agent with no known exposure and human met

295 ein product was found suitable for use as an antimicrobial agent with potent antibacterial activity,

296 Graphene oxide (GO) is an antimicrobial agent with tunable surface chemistry.

297 RE-active therapy and the development of new antimicrobial agents with activity against CRE.

298 ered an attractive target for developing new antimicrobial agents with novel mechanisms of action.

299 cells being significantly more resistant to antimicrobial agents, with increased resistance correlat

300 n part to this organism's resistance to many antimicrobial agents, with pneumonia and bacteremia as t