ライフサイエンスコーパス: antimicrobial resistance

1 , is an important part of efforts to address antimicrobial resistance.

2 to negatively affect gut microbiota or cause antimicrobial resistance.

3 idelines across Europe is necessary to limit antimicrobial resistance.

4 y relevant determinants of pathogenicity and antimicrobial resistance.

5 ctrum antimicrobials and are associated with antimicrobial resistance.

6 e emergency department (ED), contributing to antimicrobial resistance.

7 bal TB epidemic and preventing the spread of antimicrobial resistance.

8 nity and hospital infections and having high antimicrobial resistance.

9 agnostics that identify infection and detect antimicrobial resistance.

10 o be a valuable tool in the struggle against antimicrobial resistance.

11 udes detection of gene sequences that confer antimicrobial resistance.

12 , which is important considering the rise of antimicrobial resistance.

13 ritical issue facing humanity is the rise in antimicrobial resistance.

14 swabs at baseline, 3 and 12 months to detect antimicrobial resistance.

15 a probable contributor to the high burden of antimicrobial resistance.

16 y, is low in cost, and puts less pressure on antimicrobial resistance.

17 that is deteriorating due to high levels of antimicrobial resistance.

18 teric fever due to the escalating problem of antimicrobial resistance.

19 drug use or doses as well as global risk for antimicrobial resistance.

20 consumption and other known risk factors for antimicrobial resistance.

21 and mandated by the Joint Commission to curb antimicrobial resistance.

22 expanding our abilities to detect and study antimicrobial resistance.

23 cally relevant delay, even in the setting of antimicrobial resistance.

24 or use in the struggle to combat the rise of antimicrobial resistance.

25 cularly in light of the increasing burden of antimicrobial resistance.

26 identifying bacterial and fungal species and antimicrobial resistance.

27 done in support of the Global Action Plan on Antimicrobial Resistance.

28 s and provide a warning on broader issues of antimicrobial resistance.

29 quired infections and contribute to fighting antimicrobial resistance.

30 on the healthcare system, and contributes to antimicrobial resistance.

31 ildlife in the spread of clinically relevant antimicrobial resistance.

32 life dietary interventions to reduce overall antimicrobial resistance.

33 timicrobial use, which promotes emergence of antimicrobial resistance.

34 ious disease diagnostics to the screening of antimicrobial resistance.

35 lity of the spectroscopic approach to detect antimicrobial resistance.

36 eutic option that would not be vulnerable to antimicrobial resistance.

37 rk to measure and drive national progress on antimicrobial resistance.

38 tions that they have in the global threat of antimicrobial resistance.

39 resent three example analyses in the area of antimicrobial resistance.

40 r goal of WHO's global action plan to combat antimicrobial resistance.

41 ithromycin on the prevalence of impetigo and antimicrobial resistance.

42 ide-effects) and reduce the global threat of antimicrobial resistance.

43 , loss-of-function mutants of PptH displayed antimicrobial resistance.

44 ut understudied component of epidemiology of antimicrobial resistance.

45 f this approach on global challenges such as antimicrobial resistance.

46 methods to detect pneumococcal serotypes and antimicrobial resistance.

47 eutic development to preempt efflux-mediated antimicrobial resistance.

48 and shared some of their latest findings on antimicrobial resistance.

49 e antibiotic properties and ultimately break antimicrobial resistance.

50 ant genes as clinically relevant targets for antimicrobial resistance.

51 o reduce child mortality as well as increase antimicrobial resistance.

52 t could help confront the imminent crisis of antimicrobial resistance.

53 ic therapy for pneumonia depends on risk for antimicrobial resistance.

54 raits is a viable solution to the problem of antimicrobial resistance.

55 ce factors, genes involved in pertussis, and antimicrobial resistance.

56 ections and can be difficult to treat due to antimicrobial resistance.

57 ect for oropharyngeal Neisseria species with antimicrobial resistance.

58 major role in the development and spread of antimicrobial resistance.

59 utics in an age of widespread and increasing antimicrobial resistance.

60 accines within the global strategy to combat antimicrobial resistance(8).

61 rly useful for looking into the evolution of antimicrobial resistance, a major public health concern.

62 microbials, offering a strong tool to tackle antimicrobial resistance, a serious global health proble

63 The prevalence of antimicrobial resistance among many common bacterial pat

64 ty of bacterial genes encoding virulence and antimicrobial resistance (AMR) against ecological and an

65 vestigated the extent measured the burden of antimicrobial resistance (AMR) among confirmed enteric f

66 pathogens contributing to the global rise in antimicrobial resistance (AMR) are Klebsiella pneumoniae

67 ernance is an essential strategy to tackling antimicrobial resistance (AMR) at all levels: global, na

68 Antimicrobial resistance (AMR) constitutes an internatio

69 Antimicrobial Resistance (AMR) constitutes an internatio

70 We are experiencing an antimicrobial resistance (AMR) crisis, brought on by the

71 is a major cause of infection with extensive antimicrobial resistance (AMR) facilitated by widespread

72 ptible to antimicrobials but showed sporadic antimicrobial resistance (AMR) gene acquisition, and two

73 Virulence and antimicrobial resistance (AMR) gene carriage was highly

74 we have little insight into how this impacts antimicrobial resistance (AMR) gene dynamics.

75 zoonotic pathogen: Campylobacter jejuni) and antimicrobial resistance (AMR) genes ( tetW, mecA) in ai

76 ne learning, our model accurately identified antimicrobial resistance (AMR) genes in Gram-negative ba

77 ug resistant due to the presence of multiple antimicrobial resistance (AMR) genes, and two clades exh

78 c engineering, including the introduction of antimicrobial resistance (AMR) genes.

79 Antimicrobial resistance (AMR) has been identified by th

80 e (AMU) in animal agriculture contributes to antimicrobial resistance (AMR) in humans, which imposes

81 eruginosa that acquired increasing levels of antimicrobial resistance (AMR) in response to treatment.

82 cus on regional differences in aetiology and antimicrobial resistance (AMR) in the past decade (2008-

83 Antimicrobial resistance (AMR) in V. cholerae has become

84 Antimicrobial resistance (AMR) is a global threat.

85 Antimicrobial resistance (AMR) is a growing public healt

86 Antimicrobial resistance (AMR) is a growing threat with

87 Antimicrobial resistance (AMR) is a major challenge in t

88 On the other hand, antimicrobial resistance (AMR) is a major global public

89 Antimicrobial resistance (AMR) is a major threat to huma

90 Antimicrobial resistance (AMR) is a serious threat to gl

91 The increasing prevalence of antimicrobial resistance (AMR) is a significant threat t

92 Antimicrobial resistance (AMR) is a threat to global pub

93 Antimicrobial resistance (AMR) is an increasing threat t

94 Antimicrobial resistance (AMR) is an issue of upmost glo

95 tions caused by pathogens that have acquired antimicrobial resistance (AMR) is essential for resource

96 Antimicrobial resistance (AMR) is now a major global pro

97 Antimicrobial resistance (AMR) is one of the most signif

98 networks of laboratory-based surveillance of antimicrobial resistance (AMR) monitor resistance trends

99 achine learning models to accurately predict antimicrobial resistance (AMR) phenotypes from bacterial

100 The evolution of antimicrobial resistance (AMR) poses a persistent threat

101 on dairy farms in Colombia and compared the antimicrobial resistance (AMR) profiles of isolates from

102 The development of antimicrobial resistance (AMR) resulting from widespread

103 To tackle the problem of antimicrobial resistance (AMR) surveillance programmes a

104 Antimicrobial resistance (AMR) testing was performed for

105 ping, detection of mutations associated with antimicrobial resistance (AMR) to accurately predict dru

106 tand the epidemiology, serovar distribution, antimicrobial resistance (AMR), and clinical manifestati

107 The increase of antimicrobial resistance (AMR), and lack of new classes

108 ing data to identify genetic determinants of antimicrobial resistance (AMR), but they lack causal int

109 ated with isolate characteristics, including antimicrobial resistance (AMR), classic genotyping, and

110 D-19) arose at a time of great concern about antimicrobial resistance (AMR).

111 ver for the development and proliferation of antimicrobial resistance (AMR).

112 used to study the spread and acquisition of antimicrobial resistance (AMR).

113 fections is dependent on a low prevalence of antimicrobial resistance (AMR).

114 2019 may have a complex long-term impact on antimicrobial resistance (AMR).

115 gonorrhoeae plasmids can mediate high-level antimicrobial resistance (AMR).

116 es the need for advanced methods to identify antimicrobial-resistance (AMR) genes in bacterial pathog

117 norrhea treatment are threatened by evolving antimicrobial resistance and a diminished pipeline for n

118 x systems are often associated with multiple antimicrobial resistance and also contribute to the expr

119 e to emerge, together with growing levels of antimicrobial resistance and an increasing awareness of

120 ned unchanged, with no consistent effects on antimicrobial resistance and candidemia.

121 nwhile, oral antibiotics may also exacerbate antimicrobial resistance and cause systemic side effects

122 practice has been associated with increased antimicrobial resistance and cost.

123 It has been proposed that antimicrobial resistance and genome degradation has cont

124 a surface - affects their ability to evolve antimicrobial resistance and our ability to treat infect

125 ansmissibility, worsening the trajectory for antimicrobial resistance and potentially circumventing e

126 locally increase drug concentration to break antimicrobial resistance and reduce the drug's periphera

127 ill inform global estimates of the burden of antimicrobial resistance and reinforce the need for bett

128 athogen is favored by its ability to acquire antimicrobial resistance and to spread and persist in bo

129 The spread of antimicrobial resistance and vaccine escape in the human

130 and it enables rapid automated detection of antimicrobial resistance and virulence factor genes.

131 Human and poultry isolates bore more antimicrobial resistance and virulence genes and were le

132 describe Salmonella bloodstream infections, antimicrobial resistance, and age distribution at a rura

133 treptococcus species, controlling virulence, antimicrobial resistance, and biofilm formation.

134 tors to effective therapy, the prevention of antimicrobial resistance, and newer designs for clinical

135 ments (MGEs), which encode virulence, toxin, antimicrobial resistance, and other metabolic functions.

136 ing disease burden, diagnosis and detection, antimicrobial resistance, and prevention and control met

137 ptions for enteric as a result of increasing antimicrobial resistance, and therefore typhoid vaccinat

138 detecting microbial transmission, predicting antimicrobial resistance, and understanding microbe-micr

139 companied by the acquisition of mutations in antimicrobial resistance- and bacteriocin-encoding genes

140 o improve the therapeutic outcome and combat antimicrobial resistance are highlighted.

141 Identifying and understanding antimicrobial resistance are imperative for clinical pra

142 ter these structures, resulting in increased antimicrobial resistance, are explored.

143 comes, decrease costs, and curb increases in antimicrobial resistance around the world.

144 , the World Health Organization has endorsed antimicrobial resistance as a great threat to humanity.

145 ng surveillance system for enteric fever and antimicrobial resistance at the national level is recomm

146 household-level risk factors for sharing of antimicrobial resistance between humans, wildlife, and l

147 ls identified two interfaces for exchange of antimicrobial resistance: between both rodents, humans a

148 enes associated with motility, efflux pumps, antimicrobial resistance, biofilm formation, two-compone

149 oles of Bacteroides species and describe the antimicrobial resistance biogeography along the intestin

150 onorrhoeae culture is necessary to determine antimicrobial resistance, but typically requires specime

151 ationships, pathogenesis and determinants of antimicrobial resistance by sequencing the genomes of Vi

152 ndustry, which may contribute to the rise of antimicrobial resistance, carrying potential consequence

153 The Indian isolates have no chromosomal antimicrobial resistance cassette but carry the IncY pla

154 Infectious diseases (exacerbated by antimicrobial resistance) cause death, loss of quality o

155 Rationale: Antimicrobial resistance challenges therapy of pneumonia

156 cancer, is high in AN people; however, high antimicrobial resistance combined with high reinfection

157 regimen, and formulation; long-term safety; antimicrobial resistance; cost-effectiveness; and risk-b

158 s with high burden of disease or significant antimicrobial resistance could have a dramatic impact, p

159 The antimicrobial resistance crisis has persisted despite br

160 The world is in the midst of an antimicrobial resistance crisis, driving a need to disco

161 Despite the global antimicrobial resistance crisis, the epidemiology of VAP

162 In light of the global antimicrobial-resistance crisis, there is an urgent need

163 s study, we examined the association between antimicrobial resistance, CRISPR/Cas systems and virulen

164 for Disease Control and Prevention (CDC) and antimicrobial-resistance data on Typhi isolates in CDC's

165 metagenomic samples and robustly identifying antimicrobial resistance determinants from error-prone N

166 Genetic detection of antimicrobial resistance determinants predicted that all

167 Improved rapid diagnosis and antimicrobial resistance determination, such as by whole

168 correlation between genotypic and phenotypic antimicrobial resistance determinations.

169 es are addressed, including the potential of antimicrobial resistance development and how this could

170 Burgeoning problems of antimicrobial resistance dictate that new solutions be d

171 use harm to the public and may contribute to antimicrobial resistance due to potential existence of i

172 The O'Neill Review on antimicrobial resistance estimates that, left unchecked,

173 le over time, despite annual fluctuations in antimicrobial resistance gene content in the sampled gen

174 d validated on qPCR for the detection of the antimicrobial resistance gene MCR-2.

175 nterobacter cloacae) and their corresponding antimicrobial resistance gene profiles within as little

176 mates of specific target genes, including an antimicrobial resistance gene.

177 release of unmetabolized antimicrobials and antimicrobial resistance genes (ARG) into the environmen

178 published data on bacterial communities and antimicrobial resistance genes (ARGs) in the environment

179 ong the foodborne and the human populations, antimicrobial resistance genes (ARGs) may be shared by h

180 risk of bovine respiratory disease (BRD) on antimicrobial resistance genes and mutation in quinolone

181 Sequence type, antimicrobial resistance genes and plasmid replicons wer

182 ithin individuals, the highest abundances of antimicrobial resistance genes are found in the oral cav

183 vealed heterogeneity in virulence factor and antimicrobial resistance genes carried by LA-S. aureus a

184 and expanded the abundance and diversity of antimicrobial resistance genes in feces.

185 This study aims to test the presence of antimicrobial resistance genes in milk metagenome, inves

186 ation of 20 Gram-positive pathogens and four antimicrobial resistance genes in positive blood culture

187 effects on the gut resistome, a reservoir of antimicrobial resistance genes in the body, of twice-yea

188 Previously described virulence and antimicrobial resistance genes that promote the dissemin

189 for the rapid detection and surveillance of antimicrobial resistance genes will decrease the turnaro

190 gnostic techniques that detect pathogens and antimicrobial resistance genes within clinical samples p

191 ification of 20 Gram-positive bacteria, four antimicrobial resistance genes, and both Pan Candida and

192 te-specific differences in the prevalence of antimicrobial resistance genes, classes and mechanisms i

193 pre-transplant stool sample harbors 46 known antimicrobial resistance genes, while all other species

194 Cas13a into a bacteriophage capsid to target antimicrobial resistance genes.

195 h analysis uncovered the presence of several antimicrobial resistance genes.

196 ormation on serotype, virulence factors, and antimicrobial resistance genes.

197 communities and clinical samples with known antimicrobial resistance genes.

198 nrichment of potentially pathogenic taxa and antimicrobial resistance genes.

199 diverse E. coli population carrying multiple antimicrobial resistance genes.

200 lococcus aureus by recognizing corresponding antimicrobial resistance genes.

201 alignment-based methods for identifying new antimicrobial-resistance genes.

202 ive pressure for the emergence and spread of antimicrobial resistance globally.

203 Moreover, antimicrobial resistance has become an additional challe

204 Antimicrobial resistance has been declared as one of the

205 The global threat of antimicrobial resistance has driven the use of high-thro

206 The rise in antimicrobial resistance has prompted the development of

207 adication of Helicobacter pylori infections, antimicrobial resistance has substantially reduced eradi

208 n of liver abscesses, but concerns regarding antimicrobial resistance have increased the need for alt

209 The rise of gonococcal antimicrobial resistance highlights the need for strateg

210 This Review provides a detailed overview of antimicrobial resistance identification and characteriza

211 nalysis of sequence variants associated with antimicrobial resistance identified the genetic backgrou

212 ation on the gut microbiome and emergence of antimicrobial resistance in a controlled study of 149 ne

213 many publications have examined transferable antimicrobial resistance in bacteria isolated from marin

214 crobial drug usage and the growing threat of antimicrobial resistance in bacteria.

215 vel insight into the broader epidemiology of antimicrobial resistance in complex urban environments,

216 nstrate that wild-type AdeT1 does not confer antimicrobial resistance in E. coli, highlighting the im

217 A first step to combating antimicrobial resistance in enteric pathogens is to esta

218 dings have implications for the emergence of antimicrobial resistance in gonococci and how this is as

219 reatment has been linked to the emergence of antimicrobial resistance in human and animal pathogens.

220 microbial stewardship is advocated to reduce antimicrobial resistance in ICUs by reducing unnecessary

221 d interspecies QS plays an important role in antimicrobial resistance in microbial communities.

222 Antimicrobial resistance in Mycoplasma genitalium (MG),

223 may contribute to variations in the level of antimicrobial resistance in N. gonorrhoeae in different

224 Antimicrobial resistance in Neisseria gonorrhoeae is a m

225 the oropharynx may be an important source of antimicrobial resistance in Neisseria gonorrhoeae.

226 nt reservoir for genetic material conferring antimicrobial resistance in NG; however, clinical data a

227 ed virulence factors and clinically relevant antimicrobial resistance in opportunistic pathogens that

228 elopments in typhoid vaccines and increasing antimicrobial resistance in Salmonella Typhi that have s

229 to treat, in part because of the widespread antimicrobial resistance in the preeminent etiologic age

230 Antimicrobial resistance in tuberculosis (TB) is a publi

231 phenotypic and genotypic characteristics of antimicrobial resistance in typhoidal Salmonella, coveri

232 Vaccines may reduce the burden of antimicrobial resistance, in part by preventing infectio

233 Antimicrobial resistance, including in pathogens that ca

234 m-negative bacteria that are associated with antimicrobial resistance, including to colistin.

235 As antimicrobial resistance increases globally, the cost of

236 As antimicrobial resistance increases, it is crucial to dev

237 n, such as profiling genetic determinants of antimicrobial resistance, interactions with the host, po

238 Antimicrobial resistance is a global health crisis and f

239 Antimicrobial resistance is a grave threat to human life

240 The increasing prevalence of antimicrobial resistance is a serious threat to global p

241 Antimicrobial resistance is a serious threat to human he

242 Antimicrobial resistance is a significant concern to pub

243 ncome countries (LMICs), where the burden of antimicrobial resistance is greatest(5).

244 the relationship between interkingdom QS and antimicrobial resistance is largely unknown.

245 Maintenance and persistence of antimicrobial resistance is likely to vary across differ

246 ics on vertical transmission of microbes and antimicrobial resistance is not well understood.

247 Antimicrobial resistance is one of the most important th

248 Antimicrobial resistance is rapidly expanding, in a larg

249 Antimicrobial resistance is recognized as one of the gre

250 timely patient support, faster diagnosis of antimicrobial resistance is required.

251 ntibiotics in food and medical industry, the antimicrobial resistance is starting to show up in some

252 ng how bile resistance mechanisms align with antimicrobial resistance is vital to our ability to deve

253 ibiotic treatment can be effective, emerging antimicrobial resistance, limited access, and cost affir

254 Antimicrobial resistance limits treatment options and in

255 of viruses, atypical bacteria, bacteria, and antimicrobial resistance marker genes from lower respira

256 detection of H. pylori mutations that invoke antimicrobial resistance may be a useful approach to gui

257 esulted in an abundance and diverse range of antimicrobial resistance mechanisms.

258 of antibiotics and a high-rate occurrence of antimicrobial-resistance microbes.

259 nce data on Typhi isolates in CDC's National Antimicrobial Resistance Monitoring System from 1999 thr

260 Current assays of antimicrobial resistance need knowledge of mutations tha

261 With the rise of antimicrobial resistance, novel ways to treat bacterial

262 , was previously demonstrated to enhance the antimicrobial resistance of Escherichia coli.

263 Antimicrobial resistance of isolates was determined by d

264 ng) methods associated with the detection of antimicrobial resistance of two major therapeutic antimi

265 We investigated antimicrobial resistance overlap between sympatric wildl

266 xonomic and metabolic diversity and distinct antimicrobial resistance patterns.

267 modifications, such as those associated with antimicrobial resistance phenotypes, during Gram-negativ

268 There were strong associations between antimicrobial resistance, phylogeny, and epidemiology.

269 Health care-associated antimicrobial resistance places a substantial burden on

270 Rising levels of antimicrobial resistance pose serious dangers to patient

271 e resistome across body sites to uncover the antimicrobial resistance potential in the human body.

272 hington and Montreal, Quebec with phenotypic antimicrobial resistance profiles and whole genome seque

273 s and undesirable genes, 3) determination of antimicrobial resistance properties and their possibilit

274 fective antibiotic usages and to surveil the antimicrobial resistance rate.

275 and pyelonephritis are associated with high antimicrobial resistance rates among causative pathogens

276 However, antimicrobial resistance rates can differ substantially,

277 Health Organization's Global Action Plan on Antimicrobial Resistance recommends engaging multisector

278 co-transfer of multiple clinically-important antimicrobial resistance represents a particular challen

279 infection and a critical pathogen in the WHO antimicrobial resistance research and development priori

280 Examination of the genetic basis of antimicrobial resistance revealed multiple macrolide res

281 Examination of the genetic basis of antimicrobial resistance revealed multiple macrolide res

282 With the alarming rise of antimicrobial resistance, studies on bacteria-surface in

283 ere, we implement WGS within the established Antimicrobial Resistance Surveillance Program of the Phi

284 In the context of high levels of antimicrobial resistance, switching from azithromycin to

285 sed to expand the availability of gonococcal antimicrobial resistance testing for both clinical and s

286 of which are more predisposed to developing antimicrobial resistance than others.

287 roperties of PNPs appear essential to combat antimicrobial resistance that is currently threatening t

288 rtance and demand for tackling challenges in antimicrobial resistance, the proposed method is applied

289 In the face of growing antimicrobial resistance, there is an urgent need for th

290 constitutes the only documented mechanism of antimicrobial resistance to apramycin.

291 Antimicrobial resistance to common antibiotics was low.

292 for the dissemination of clinically relevant antimicrobial resistance to the wider environment.

293 In addition to antimicrobial resistance, treatment failures are increas

294 Isolates were characterized for antimicrobial resistance, virulence genes, and diversity

295 se the burden of typhoid and may also impact antimicrobial resistance, water, sanitation, and hygiene

296 Considering antimicrobial resistance, we investigated the impact of

297 Rates of antimicrobial resistance were high, with 17.6% (95/541)

298 important consideration in an era of growing antimicrobial resistance, when we are looking for new wa

299 for other indications, ongoing monitoring of antimicrobial resistance will be required.

300 and have been associated to the increment in antimicrobial resistance worldwide.