ライフサイエンスコーパス: antioxidative

1 pes, olive and broccoli wastes, the relative antioxidative abilities of lettuces cultivated in greenh

2 red to be H2O2-dependent with an increase in antioxidative ability for H-SeB.

3 available antioxidant assays to evaluate the antioxidative ability of MRPs, and parameters influencin

4 rious foods and beverages, mechanisms of its antioxidative action have not been fully clarified.

5 results have important implications for the antioxidative actions of *NO and its effects on cellular

6 late pancreatic insulin secretion or through antioxidative actions.

7 Herein we compared antioxidative activities (AA) of 25 free L-amino acids (

8 itions delayed pericarp browning, maintained antioxidative activities and biochemical characteristics

9 Antioxidative activities of phenolic compounds (caffeic

10 suggesting that they will exhibit comparable antioxidative activities.

11 n pericarp browning, biochemical quality and antioxidative activities.

12 for their basic physicochemical properties, antioxidative activity as well as subjected to the quant

13 f sugars, organic acids, total phenolics and antioxidative activity have been evaluated among three d

14 roducing Pacific hake hydrolysates with good antioxidative activity in various assays and similar eff

15 The antioxidative activity measured with the DPPH and FRAP a

16 ide fractions (>5kDa, 3-5kDa and <3kDa) with antioxidative activity obtained from a cod protein hydro

17 on the chemical stability of SSO and on the antioxidative activity of 40muM alpha-tocopherol in SSO

18 Thus, we describe a novel antioxidative activity of a previously characterized bio

19 tigates changes in the anti-inflammatory and antioxidative activity of anthocyanins from purple basil

20 ncentration of polyphenols and iridoids, and antioxidative activity of brewed beer.

21 of intact resorcinol is proportional to the antioxidative activity of HOCl scavengers.

22 The results indicate that the antioxidative activity of KFEE is defined by the relativ

23 In the current study, the antioxidative activity of KFEE, which contains polypheno

24 To measure antioxidative activity of plant extracts we used three a

25 The antioxidative activity of the crude hydrolysates and the

26 Since no clear correlation between the antioxidative activity of the FPH and the course of lipi

27 ht peptides thus seemed to contribute to the antioxidative activity of the peptide fractions, and Tyr

28 position, functional properties and in vitro antioxidative activity of the peptidic fraction of carot

29 ckberry leaf extract exhibited cytotoxic and antioxidative activity on human colon cancer cells.

30 Loss of EC-SOD-mediated antioxidative activity resulted in significant accumulat

31 c acid-rich fraction, showed the most potent antioxidative activity whereas the polymeric and anthocy

32 Cholesterol acceptor capacity and antioxidative activity, representing two key cardioprote

33 As markers for antioxidative activity, the intracellularly generated RO

34 activity like antibacterial, antifungal, and antioxidative activity.

35 Compound 13 was found to pose an antioxidative activity.

36 probiotic L. rhamnosus strain GG had potent antioxidative activity: dampening reactive oxygen specie

37 Furthermore, in vivo treatment with the antioxidative agent N-acetyl-L-cysteine resulted in reve

38 that can function as an antiinflammatory and antioxidative agent, and as such, it may have atheroprot

39 Interrelations with other antioxidative agents and oxidative stressors, such as sm

40 The transepithelial transport of an antioxidative and ACE inhibitory peptide, VLPVPQK (named

41 aturated fatty acids and demonstrated higher antioxidative and angiotensin-1 converting enzyme (ACE)

42 n the endothelial cells created by excess of antioxidative and anti-inflammatory agents NAC and mito-

43 e such possible process, a deficiency of the antioxidative and anti-inflammatory enzyme heme oxygenas

44 ed polyketides from P. malabarica as natural antioxidative and anti-inflammatory functional food ingr

45 By documenting potent antioxidative and anti-inflammatory functions, preclinic

46 luding proinflammatory cytokines, and exerts antioxidative and anti-inflammatory functions.

47 Prior research has suggested that the antioxidative and anti-inflammatory potential of fruits

48 ntake of dietary flavonoids, known for their antioxidative and anti-inflammatory properties, affects

49 n E isoform gamma-tocotrienol possesses both antioxidative and anti-inflammatory properties, we sough

50 argely involved in xenobiotic metabolism and antioxidative and anti-inflammatory protection, as well

51 adipose-derived cytokine that may act as an antioxidative and anti-inflammatory protein.

52 a high-fat dietary habit via regulations of antioxidative and anti-inflammatory responses.

53 ession of Trx--the redox protein with potent antioxidative and antiapoptotic properties--may play a p

54 im of this study was to evaluate and compare antioxidative and antihypertensive activities of Longiss

55 Pig meat showed antioxidative and antihypertensive activities, heat trea

56 Antioxidative and antihypertensive bioactive peptides we

57 functional food since it is a good source of antioxidative and antihypertensive peptides.

58 e results of this paper revealed significant antioxidative and antimicrobial activity of SE1 and SE2,

59 exert significant endothelial protection by antioxidative and antinitrative effects.

60 Antioxidative and antiproliferative assays demonstrated

61 ouse and human studies have demonstrated the antioxidative and atheroprotective effects of PON1.

62 Nrf2, in turn, induces a number of antioxidative and carcinogen-detoxifying enzymes.

63 ation of bioactive compounds and to exert an antioxidative and chemopreventive effects.

64 Nrf2, a transcriptional factor that induces antioxidative and cytoprotective pathways.

65 proapoptotic effects and that .NO exerts an antioxidative and cytoprotective role.

66 lular defense by initiating transcription of antioxidative and detoxification genes.

67 ed insulin biosynthesis can overwhelm the ER antioxidative and folding capacity, causing an imbalance

68 Antioxidative and functional properties of protein hydro

69 typed for common functional polymorphisms in antioxidative and neurodevelopmental genes.

70 thy individuals genotyped for a selection of antioxidative and neurodevelopmental genes.

71 s are of great current interest due to their antioxidative and possible anticarcinogenic activities.

72 etary catechins are phytochemicals with both antioxidative and prooxidative stress properties.

73 as immunomodulatory interleukin 6 as well as antioxidative and proproliferative molecules (HMOX1, VEG

74 In contrast, an increase in antioxidative and reducing capacity of stored cakes was

75 icular, the changes in antioxidants content, antioxidative and reducing capacity, and Maillard reacti

76 reatment of this animal model we utilized an antioxidative and water soluble nanoparticle known as gl

77 europrotective due to its anti-inflammatory, antioxidative, and pro-myelinating effects.

78 , and has been shown to have osmoregulatory, antioxidative, antiapoptotic, anti-inflammatory, and ant

79 This study documents the antioxidative, anticancer and enzyme-inhibiting properti

80 We investigated their antioxidative, antimicrobial and haemolytic activities a

81 -pressed oils contained compounds that exert antioxidative, antimicrobial, acetylcholinesterase inhib

82 injury in vivo but has minimal effect on the antioxidative/antinitrative protection of adiponectin.

83 ts, among them, antimicrobial, antidiabetic, antioxidative, antiobesity and antihypertensive effects.

84 Kiwifruits exhibit antioxidative, antiproliferative, antiinflammatory, anti

85 In general, the various antioxidative assays correlated well with the total phen

86 However, in some of the antioxidative assays some species with low total phenoli

87 Antioxidative behavior of 5CQA relative to trolox (Tx) t

88 Antioxidative bioactive peptide was successfully identif

89 e relative indices enables the comparison of antioxidative capacities obtained in various studies.

90 found to be positively correlated with total antioxidative capacity and inversely related to the RDS

91 ars followed by assessment of their in vitro antioxidative capacity by LC-MS and oxidation/reduction

92 chimeric Ag receptor (CAR) to increase their antioxidative capacity by metabolizing H2O2.

93 d macrophages, and platelets, as well as the antioxidative capacity of different antioxidants.

94 ility at different pH, thermal stability and antioxidative capacity of glycated WP were increased, es

95 This study aimed at unravelling the antioxidative capacity of low molecular weight compounds

96 The thermal stability and antioxidative capacity of the adducts were higher than t

97 is that TCM cells possess relatively greater antioxidative capacity than TEM cells.

98 as obtained by the systemic elevation of the antioxidative capacity through daily administration of R

99 sponse element (ARE) regulates intracellular antioxidative capacity to combat oxidative stress.

100 Subjects who had ACS had higher HII (less antioxidative capacity) compared with controls (1.57 vs.

101 tracellular oxidant production outweighs the antioxidative capacity, lies at the basis of many diseas

102 ed with reduced cancer risk because of their antioxidative capacity.

103 ne (AFMK) was investigated for its potential antioxidative capacity.

104 PCs and thus, can alter their scavenging and antioxidative capacity.

105 ontains high levels of anti-inflammatory and antioxidative compounds such as ginnalins, but little is

106 The antioxidative compounds were extracted by ultrasonic tre

107 Coincidently, antioxidative compounds were not induced in infected MtR

108 The in vitro digestion released the antioxidative compounds, leading to higher bioaccessibil

109 NI and BEN showed mild toxicity at effective antioxidative concentrations derived from DPPH and ABTS

110 d changes in nerve function, metabolism, and antioxidative defense are corrected by the dose of ARI (

111 was achieved due to upregulation of the key antioxidative defense enzyme activities rather than chan

112 sual and generally unexpected small group of antioxidative defense genes appear to have increased exp

113 A small group of antioxidative defense genes were found in this populatio

114 Many genes that are frequently considered antioxidative defense genes, including most of the GSH p

115 mplified expression of only a few additional antioxidative defense genes.

116 ified superoxide dismutase 2 (SOD2)-mediated antioxidative defense in the genetic allele's susceptibi

117 a modulated immune repertoire and induced an antioxidative defense mechanism to maintain homeostasis

118 Antioxidative defense systems are not mobilized as expec

119 lasts contains multiple proteins involved in antioxidative defense, protein folding, and repair.

120 ione, suggesting a general compromise of the antioxidative defense.

121 nt and lower expression of genes involved in antioxidative defenses and signaling, suggesting that th

122 lly linked to maintain redox homeostasis and antioxidative defenses at normal (37 degrees C) temperat

123 tein levels, with corresponding induction of antioxidative defenses in OLs exposed to cytokines via A

124 rf2 transcription factor and upregulation of antioxidative defenses occurs in astrocytes infected wit

125 e indicates that exercise training evokes an antioxidative effect in CHF.

126 The antioxidative effect of lipophilized caffeic acid was as

127 The antioxidative effect of sitosterol at 1, 2 and 5% levels

128 ination of water, may be responsible for the antioxidative effect of sitosterol at frying temperature

129 Atorvastatin exerted a profound antioxidative effect on vascular fatty lesions.

130 and necrosis in a manner consistent with its antioxidative effect.

131 ity of stripped soybean oil (SSO) and on the antioxidative effectiveness of alpha-tocopherol in SSO.

132 low total phenolic content also showed good antioxidative effects indicating that some other co-extr

133 The antioxidative effects of GCCNP were assessed in mice pri

134 nce assay was used to evaluate any potential antioxidative effects of ODQ.

135 gests that NaPB exerts anti-inflammatory and antioxidative effects via inhibition of these small G pr

136 shoots could have contributed towards their antioxidative effects.

137 ynaptic and extrasynaptic) NMDARs induced no antioxidative effects.

138 ellular energy metabolism and that may exert antioxidative effects.

139 d for further research to reach both optimal antioxidative efficacy and sensory properties.

140 Analysis of classic antioxidative enzyme activities showed little change bet

141 cellular H2O2 production with the change in antioxidative enzyme activity, and the restoration of ch

142 st, training increased the expression of the antioxidative enzyme genes by approximately 100%.

143 hology of cerebral malaria, we show that the antioxidative enzyme glutathione reductase (GR) is inact

144 of PARP-1 and topoisomerase IIbeta, loss of antioxidative enzyme induction and attenuated protection

145 RE (electrophile response element)-regulated antioxidative enzyme QR.

146 correlates with increased expression of the antioxidative enzyme quinone reductase (QR).

147 Superoxide dismutase 2 (SOD2) is a crucial antioxidative enzyme that is found in mitochondria.

148 idoreductase (AOR) from the rat is a phase 2/antioxidative enzyme that is known to catalyze the reduc

149 s further characterized as an Nrf2-regulated antioxidative enzyme that reduces carbon-carbon double b

150 Correspondingly, the expression of an antioxidative enzyme, 2-Cysteine peroxiredoxin (BxPrx),

151 hat increasing the activities of these major antioxidative enzymes above wild type levels does not de

152 -1 to the EpRE resulting in the induction of antioxidative enzymes and subsequent protection against

153 ncreased HO activity, which induces arterial antioxidative enzymes and vasoprotection in a mouse and

154 properties of nanofactories that consist of antioxidative enzymes encapsulated in metal-organic fram

155 O1 and NQO2 to investigate the role of these antioxidative enzymes in a two-stage model of inflammato

156 Lead is known to induce phytochelatins and antioxidative enzymes in vetiver; however, the overall i

157 onal role of ERbeta-mediated upregulation of antioxidative enzymes indicated protective effects again

158 NADPH oxidase, as well as the suppression of antioxidative enzymes involved in ROS clearance, the und

159 addition, the intracellular distribution of antioxidative enzymes may be modulated to regulate or fa

160 mes Cyp2e1 and Cyp4a14, higher expression of antioxidative enzymes Sod2, Gpx1, and Nqo1, without chan

161 The overexpression of antioxidative enzymes such as CuZn-superoxide dismutase

162 lear factors essential for the expression of antioxidative enzymes such as GPX3 and catalase.

163 e oxygen species, which can be detoxified by antioxidative enzymes, including catalases.

164 timulation of the activities of a variety of antioxidative enzymes, reduction in proinflammatory cyto

165 was increased, while mRNA expression for the antioxidative enzymes, SOD1, GPx1 and HO-1, was reduced

166 ucible genes included known detoxication and antioxidative enzymes.

167 medicinal/pharmaceutical applications of its antioxidative features, this compound in planta and its

168 the first report showing that TcSOD2 has an antioxidative function and demonstrates that T. castaneu

169 The antioxidative function of carnosol relies on another mec

170 To investigate the mechanisms underlying the antioxidative function of DJ-1 in relation to SOD1 activ

171 Thus antioxidative gelatin hydrolysate with negligible undesi

172 Specifically, enhanced antioxidative gene expression and the lack of differenti

173 observed in DF regions, notably an enhanced antioxidative gene expression.

174 egulation of PARP-1 attenuates TOT-dependent antioxidative gene induction.

175 r role for Nrf2 and ERalpha in TOT-dependent antioxidative gene regulation.

176 iption factor that up-regulates a battery of antioxidative genes and cytoprotective enzymes that cons

177 o-Nrf2 protein to regulate the expression of antioxidative genes and viral genes.

178 rythroid 2-related factor 2 (NRF2)-dependent antioxidative genes.

179 pressing the transcription of Nrf2-dependent antioxidative genes.

180 tive oxygen species (ROS), which trigger the antioxidative glutathione (GSH) response necessary to bu

181 ecause selenium is an essential component of antioxidative glutathione peroxidases (GPx).

182 The antioxidative GSH pathway thus plays an unexpected role

183 rotein isolate was hydrolyzed to an in vitro antioxidative hydrolysate, followed by transglutaminase-

184 IL-6 pretreatment induced the antioxidative injury proteins, ref-1 and GPX1, decreased

185 results together, we have uncovered a novel antioxidative mechanism by which PML regulates cellular

186 A ubiquitous antioxidative mechanism for regulating cellular redox ba

187 .g. at physiological pH) SPLET is the likely antioxidative mechanism of 5CQA with extremely high rate

188 It was found that SET-PT is not a plausible antioxidative mechanism of 5CQA.

189 ults suggest that an upregulation in central antioxidative mechanisms and suppressed central prooxida

190 that long-term E2 treatment improves CHF by antioxidative mechanisms that involve the upregulation o

191 ect on autonomic activity in CHF via central antioxidative mechanisms.

192 for thermodynamic consideration of the major antioxidative mechanisms: HAT (Hydrogen Atom Transfer),

193 meroterpenoids might serve as potential lead antioxidative molecules for use in pharmaceutical and fo

194 Additional in vitro studies showed antioxidative neuroprotective effects as well as the abi

195 city, anti-Alzheimer's disease activity, and antioxidative/neuroprotective effects.

196 FBS and RD hydrolysates have a potential as antioxidative neutraceutical ingredients.

197 r factor erythroid 2-related factor 2 (Nrf2) antioxidative pathway.

198 cleotide biosynthesis, and the GSH-dependent antioxidative pathway.

199 esponse, we examined several major oxidative/antioxidative pathways and found that atheroprotective f

200 ioxidant that functions independent of other antioxidative pathways in the cellular defense against R

201 Additionally, inactivated antioxidative pathways, increased reactive oxygen specie

202 FXR activation induced antioxidative pathways, which was confirmed by a marked

203 There is high potential that antioxidative peptides from rice bran might also be prod

204 Peroxiredoxin 4 (Prdx4), an ER-specific antioxidative peroxidase can utilize luminal H2O2 as dri

205 ulin p<0.0001, tropomyosin alpha4 p=0.0108), antioxidative (peroxiredoxin 2 p=0.0092), and anti-infla

206 maximize possible health benefits of cereal antioxidative phytochemicals.

207 arboxyl group) and molecular conformation in antioxidative potency of dihydrocaffeic acid (DHCA) and

208 nolic and terpenoid compounds as well as the antioxidative potency of fruit and their parts, such as

209 The sour beers had several times higher antioxidative potential and significantly higher polyphe

210 ls in the creation of the nutritional value, antioxidative potential and stability of the lipid fract

211 The antioxidative potential of applied teas was significant

212 Different antioxidative potential of isolated peptide were assesse

213 For some vegetables, an increase in the antioxidative potential was observed as a result of cook

214 ly used as a source of polyphenols with high antioxidative potential, as well as fiber; thus introduc

215 Oregano and rosemary showed also some antioxidative potential.

216 e inadequate in vitro and in vivo studies on antioxidative potentials of fermented versus unfermented

217 nal redox balance by assessing oxidative and antioxidative processes in kidneys of brain-dead rats af

218 T. arduini extract could be responsible for antioxidative/prooxidative mechanisms and would help in

219 These included two proteins with antioxidative properties (peroxiredoxin and superoxide d

220 rate-limiting step in heme degradation, has antioxidative properties and protects cells from various

221 Mechanisms of antioxidative properties are discussed.

222 iplasmic proteins - show enrichment of their antioxidative properties between the 695 strains with a

223 Antioxidative properties for raw vegetables were obtaine

224 Metallothioneins with their antioxidative properties may help to attenuate the infla

225 In this work, we sought to determine the antioxidative properties of a lipid-soluble derivative o

226 iably invoked when explaining the biological antioxidative properties of beta-carotene.

227 This increase was reflected in the improved antioxidative properties of breads, especially after the

228 The antioxidative properties of E2 were also associated with

229 n this study, we investigated, in vitro, the antioxidative properties of fractions obtained from a co

230 The antioxidative properties of Pacific hake hydrolysates an

231 y (ORAC) assay has been used to quantify the antioxidative properties of phytonutrients in fruit and

232 udy evaluated the polyphenol profile and the antioxidative properties of Plinia trunciflora (O.

233 ontaining amino acids might be attributed to antioxidative properties of pyrroles or amino acids.

234 Changes in chemical composition and antioxidative properties of rye ginger cakes during thei

235 ve effects are possibly mediated through the antioxidative properties of selenoenzymes.

236 In the current work, we studied the antioxidative properties of six fruits: rosehip, chokebe

237 Their antioxidative properties protect the eye from many retin

238 l levels tend to enrich their proteomes with antioxidative properties, and speculate as to why that i

239 omponents have been shown to differ in their antioxidative properties, and their localisation in emul

240 t potentially be nutraceutical peptides with antioxidative properties.

241 s (diCQAs) have been found to possess marked antioxidative properties.

242 heir catalytic chain-breaking and preventive antioxidative properties.

243 Ginkgo biloba leaves, has been shown to have antioxidative properties.

244 can contribute to the antimutagenic and the antioxidative property of Allium vegetables.

245 These findings suggest that the antioxidative property of L. guynianum is may be related

246 mma-induced IL-27 production and AHR via its antioxidative property.

247 oxygen species levels, indicating increased antioxidative protection, as well as lower sensitivity t

248 thway in lungs, suggesting that loss of this antioxidative protective response is a key factor in the

249 13, member A (FAM213A), a peroxiredoxin-like antioxidative protein, was repressed transcriptionally b

250 We also discovered a weakened antioxidative response and diminished expression of BM n

251 GAA induces antioxidative response and inhibits accumulation of exce

252 (SESN2) is found to mediate GAA function in antioxidative response and RPE survival upon oxidative s

253 ngs identify repression of the NRF2-mediated antioxidative response as a key contributor to the prema

254 spholipid oxidation products that induced an antioxidative response dependent on the transcription fa

255 ROS is not important in the induction of the antioxidative response or cellular death by ATO.

256 nt increase in SIRT1 expression generates an antioxidative response that contributes to reactive oxyg

257 peripheral and lumenal proteins involved in antioxidative response, including peroxiredoxins, m-type

258 The pattern was consistent with a strong antioxidative response, particularly of genes activated

259 Despite the activation of this antioxidative response, ROS may not be important in ATO-

260 We hypothesized that stimulating opposing antioxidative responses in astrocytes, as well as neuron

261 1, which further decreases Nrf2 function and antioxidative responses to S Typhimurium infection, even

262 rotein 24 (mVP24) as a modulator of the host antioxidative responses, but the molecular mechanism rem

263 ciated with keratinocyte differentiation and antioxidative responses, while inhibiting the expression

264 itochondrial dysfunction, and Nrf2-modulated antioxidative responses.

265 acts (SeB) and selenocompounds on growth and antioxidative status in human colon cancer cells was inv

266 e, creatinine, and improved liver, and renal antioxidative status.

267 An antioxidative stress array analysis of neurons treated w

268 e previously reported that the expression of antioxidative stress enzymes is upregulated by trans-hyd

269 ced tubular damage via anti-inflammatory and antioxidative stress mechanisms is unknown.

270 ern, possibly due to stimulation of cellular antioxidative stress mechanisms.

271 due to AHR-regulated activation of the NRF2 antioxidative stress pathway.

272 It displayed antioxidative stress potential in assuaging H(2)O(2) ind

273 ques and evaluated for antihyperglycemic and antioxidative stress potentials.

274 GSH-spermidine bioconjugate, involved in the antioxidative stress protection system of parasitic prot

275 ch with higher affinity and stimulate higher antioxidative stress response element (ARE) reporter act

276 tumorigenesis in mice, but its roles in the antioxidative stress response or its involvement in neur

277 or suppressor HACE1 plays a role in the NRF2 antioxidative stress response pathway and in neurodegene

278 eased oxidative stress in brain and that the antioxidative stress response was impaired.

279 2 (NRF2), a master regulator of the cellular antioxidative stress response, is deregulated in both ca

280 y light-inducible proteins, ion homeostasis, antioxidative stress, detoxification, and biosynthetic e

281 Its mechanisms are believed to be related to antioxidative stress.

282 ase in particular, and the native biological antioxidative system in skin in general.

283 alkylate glutathione, thereby inhibiting the antioxidative system of the cell, whereas the iron speci

284 me catalase, which is part of the biological antioxidative system present in skin.

285 e, the activity of enzymes involved in plant antioxidative system via ascorbate-glutathione cycle, as

286 tes that T. castaneum may use an alternative antioxidative system when the SOD2-based system fails.

287 The complexity of plant antioxidative systems gives rise to many unresolved ques

288 interactions between the complex, networking antioxidative systems in restricting ROS accumulation or

289 The different soluble antioxidative systems, in particular peroxiredoxins, acc

290 fied genes do not appear to be involved with antioxidative systems, reflecting the complexity of the

291 ife forms were obliged to develop additional antioxidative systems.

292 n-black chokeberry (5% w/v) mixture was more antioxidative than the respective controls separately.

293 re randomized in the Deprenyl and Tocopherol Antioxidative Therapy of Parkinsonism trial to receive d

294 ction; cardiac defects can be prevented with antioxidative therapy.

295 atory ATPase is a potential novel target for antioxidative therapy.

296 med RNAi and also assessed the phenotype and antioxidative tolerance of the knockdown of TcSOD2 by ex

297 using Nrf2 inducers in chemoprevention, this antioxidative transcription factor may also act as a pro

298 h protein Keap1, a negative regulator of the antioxidative transcription factor Nrf2, binds to CUL3 a

299 ized that FAEs are capable of activating the antioxidative transcription factor nuclear factor (eryth

300 supplement containing glutamine dipeptides, antioxidative vitamins and trace elements, and butyrate