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1 ed R-loops, where the two DNA strands remain antiparallel).
2 other and a lower capacitance when spins are antiparallel.
3 ical axes are oriented either in parallel or antiparallel.
4 ks run diagonally between connected pairs of antiparallel actin filaments and are oriented at an angl
5 inated by a pseudo-chain of Pt-Pt dimers and antiparallel alignment of the azide substituents, in com
6 Magnetization switching between parallel and antiparallel alignments of two magnetic layers in magnet
7 Dimerization is mediated by formation of an antiparallel alpha-helical coiled-coil involving residue
11 urements, very important differences between antiparallel and parallel ion pair-pi interactions are i
12 ally limited to parallel (ferroelectric) and antiparallel (antiferroelectric) collinear alignments of
13 y limited agreement with either parallel- or antiparallel-arranged dimer structures when spin labels
15 odel to approximate the compact parallel and antiparallel arrangement of alpha-helices and beta-stran
21 ith a significant fraction of intermolecular antiparallel beta sheet FP structure with adjacent stran
23 her proportion of intermolecular-beta-sheets+antiparallel beta sheets and lower alpha-helix had great
24 beta-sandwich topology formed by 2 sheets of antiparallel beta strands stabilized by the hallmark dis
25 28 shares a "mog1p"-fold consisting of seven antiparallel beta strands stacked between alpha helices.
26 structure shows AtDIR6 as an eight-stranded antiparallel beta-barrel that forms a trimer with spatia
27 fied fold comprised of a compact 12-stranded antiparallel beta-sandwich wrapped in two short alpha he
28 vealed a novel fold comprising a four strand antiparallel beta-sheet and two helical turns stabilized
29 eptide demonstrates that the out-of-register antiparallel beta-sheet arrangement of monomers also occ
30 ved for the NTAIL protein that folds into an antiparallel beta-sheet at the A/W interface and present
31 The reason is that NMR data strongly suggest antiparallel beta-sheet calcitonin assembly, whereas mod
32 iophage P22, but TTPA contains an additional antiparallel beta-sheet carrying a lectin-like domain th
34 presence of hydrophobic crowders reduces the antiparallel beta-sheet content of fibrils, whereas hard
35 actin reveals an amphipathic hydrogen-bonded antiparallel beta-sheet dimer that binds chloride anions
36 were dimerized to form a large 10-stranded, antiparallel beta-sheet flanked by alpha-helices on each
41 orms a novel protein fold of a four-stranded antiparallel beta-sheet stabilized by a crossing-over al
42 ur-residue alpha-helix and one three-residue antiparallel beta-sheet stabilized by two disulfide bond
43 ver, it adopts the canonical triple-stranded antiparallel beta-sheet structure of WW domains when bou
44 peptide chain is sufficient to nucleate some antiparallel beta-sheet structure; addition of beta-capp
45 ular copper concentration, and the amount of antiparallel beta-sheet structures were significantly ch
46 ment that is necessary for oligomers with an antiparallel beta-sheet to propagate into fibrils that h
47 alpha-helices and a layer of three-stranded antiparallel beta-sheet with flexible N and C termini.
48 esolution of 1.79 angstrom revealed a single antiparallel beta-sheet with six conserved cysteine resi
49 cystatin-like fold composed of a 5-stranded antiparallel beta-sheet wrapped around a 5-turn alpha-he
50 protein structures lead to the formation of antiparallel beta-sheet, beta-turns, intermolecular beta
51 ovel fold organized around a central core of antiparallel beta-sheet, showing an N-terminal alpha/bet
52 intrinsic helicity, while both parallel and antiparallel beta-sheet-like structures are realized.
53 nal amyloid assembly and further reveal that antiparallel beta-sheet-rich amyloids can be functional
57 refibrillar oligomers that consist of mainly antiparallel beta-sheets and fibrillar oligomers with on
59 rin complexes require (1) an increase in PF4 antiparallel beta-sheets exceeding approximately 30% (ac
60 n core features a globular architecture with antiparallel beta-sheets forming a central beta sandwich
61 S is unique in that its amyloids are rich in antiparallel beta-sheets instead of the more common para
62 fold like architecture which consists of two antiparallel beta-sheets with 7 main strands, packing ag
63 otyrosine vs lysine, coassemble as stacks of antiparallel beta-sheets with precisely patterned charge
64 beta-sheets (recognized by antiserum OC) or antiparallel beta-sheets, beta-solenoids, beta-barrels,
65 housed within a flexible loop connecting two antiparallel beta-sheets, flanked by disordered N- and C
66 SA2 nanocarriers are built of interdigitated antiparallel beta-sheets, which bear little resemblance
67 All three WW domains display a similar three antiparallel beta-strand structure and interact with the
70 te that formation of hairpins connecting two antiparallel beta-strands determines overall folding.
71 allelic mutations in WDR1 affecting distinct antiparallel beta-strands of Aip1 were identified in all
72 ss a typical Ig-like fold encompassing seven antiparallel beta-strands organized in two beta-sheets,
73 rms a squashed beta-barrel consisting of six antiparallel beta-strands similar to what was observed i
74 n inhibitor cystine knot structure, with two antiparallel beta-strands stabilized by three disulfide
75 ised of two layers of beta-sheets possessing antiparallel beta-strands with each being anchored by a
76 a nine-stranded beta-barrel fold with mostly antiparallel beta-strands, and the loops extending out t
79 regates (1604cm(-1)), H-bonded parallel- and antiparallel-beta-sheets (1690cm(-1)) and H-bonded beta-
80 were positively correlated to intermolecular+antiparallel-beta-sheets and negatively with beta-turn+
82 the Notch1-DLL4 complex reveals a two-site, antiparallel binding orientation assisted by Notch1 O-li
83 also stabilized and rearranged into a novel antiparallel bundle associated with the spindle pole bod
84 spindle bipolarity requires the microtubule antiparallel bundler PRC1/Ase1 to recruit CLASP/Cls1 to
85 ified oMAP4 aligns dynamic microtubules into antiparallel bundles that withstand motor forces in vitr
86 a result, when intersecting microtubules are antiparallel, canonical transport of one microtubule alo
88 hat has been experimentally observed for the antiparallel CC of the dynein stalk region and the nucle
89 lain why nature has evolved the principle of antiparallel chain orientation and has not used the para
92 embrane protein and by combining parallel or antiparallel chloride and proton gradients, we show that
94 urprisingly, this structure is a continuous, antiparallel coiled coil where GCN4-p1 pairs with myosin
96 ed by a central helical domain that forms an antiparallel coiled-coil motif and mediates the dimeriza
99 protocadherin-15 EC1-3 molecules forming an antiparallel complex with two cadherin-23 EC1-2 molecule
100 ysiological solutions have an intramolecular antiparallel configuration that is distinct from the int
102 a CC interface is different for parallel and antiparallel configurations, both are characterized by a
104 in fact, the DFNKF sequence is not stable in antiparallel conformation, suggesting that the residue f
110 magainin 2 derivative displayed a homochiral antiparallel dimer association featuring a "phenylalanin
111 P have provided evidence for formation of an antiparallel dimer at pH 5.5, stabilized by stacking of
113 inimal B-repeat construct (Brpt1.5) forms an antiparallel dimer in the presence of 2-3 Zn(2+) ions.
115 ctin is important for its bioactivity and an antiparallel dimer of teixobactin is the minimal binding
116 The fundamental units of the crystals are antiparallel dimer ribbons of SERCA, known for decades a
120 r-transmembrane helix domains folded into an antiparallel dimer, where the orientation of the two dom
124 nce transporters from this family consist of antiparallel dimers that resemble the inverted repeats p
126 s without tail-head interaction, tail-folded antiparallel dimers, tail-folded antiparallel tetramers,
127 ngth proceeds from folded monomers to folded antiparallel dimers, tetramers, and hexamers that unfold
128 at the tripartite motif (TRIM) of KAP1 forms antiparallel dimers, which further assemble into tetrame
129 plex structures: a parallel, a hybrid and an antiparallel DNA and a parallel RNA, in the presence of
130 led angles, and the lines are represented by antiparallel DNA crossover tiles of variable lengths.
131 th conventional double stranded DNA and with antiparallel DNA double crossover molecules, it is clear
132 cation occurs semidiscontinuously due to the antiparallel DNA strands and polarity of enzymatic DNA s
133 ss of bilayer cholesterol concentration, the antiparallel double helix (ADH) conformation was observe
135 we provide a structural perspective on known antiparallel duplex structures in which at least one str
138 on analysis, we found evidence for a similar antiparallel EC1-4 interaction in non-clustered Pcdh fam
142 arized, motile comet tails that associate by antiparallel filament bundling to form bipolar, DNA-segr
144 d a dense and anisotropic array of elongate, antiparallel filaments, whereas myosin II was organized
146 ils to induce a conformational change in the antiparallel fold of OTABA, subsequent additions of OTA
147 ated to adopt a novel type of mixed parallel/antiparallel fold-back DNA structure, which is stabilize
148 yQ fibrils might also be a zipper layer with antiparallel four-stranded stretches as this structure s
149 longer myosin-10 segments in these parallel/antiparallel fusions are dynamic and do not fold coopera
150 ermodynamically stable species (parallel and antiparallel G-quadruplex in K+ and Na+, respectively).
153 quadruplex structure containing two central antiparallel G-tetrads and six i-motif C-C+ base pairs.
155 ive microtubule sliding in both parallel and antiparallel geometries, an activity that has been sugge
156 ) binding aptamer (OTABA) that folds into an antiparallel GQ in the absence and presence of target OT
157 uence in ssDNA which forms both parallel and antiparallel GQs, dsDNA displays only parallel folding.
158 discoidal structure, which included pairs of antiparallel helices of apolipoprotein AI circumscribing
160 solution of 2D IR spectroscopy, parallel and antiparallel helix associations were identified by vibra
161 nserved PRMT domain architecture and form an antiparallel heterodimer that corresponds to the canonic
163 ith those present in the prototypical linear antiparallel heterotetramer as well as recently reported
166 nsmembrane domain and forms a highly unusual antiparallel homodimer that is stably associated with MC
167 eterologous binding partners, BECN1 forms an antiparallel homodimer via its coiled-coil domain (CCD).
168 ork, we sought to design a set of orthogonal antiparallel homodimeric coiled coils using a computatio
171 abilizing propeller type loops, shifting the antiparallel htel-22 into hybrid or parallel quadruplexe
172 with oligonucleotides forming mixed parallel/antiparallel hybrid-1 and hybrid-2 topologies {e.g. d[TT
173 tional form of human telomeric G-quadruplex (antiparallel, hybrid, parallel monomers or a 48 nt seque
174 N-terminal edge of the BamA catalyst has an antiparallel hydrogen-bonded interface with the C-termin
176 the M10:O1 complex displays a chevron-shaped antiparallel Ig-Ig architecture held together by a conse
178 ts that G monomers can re-associate, through antiparallel interactions between fusion domains, into d
180 kinetic constants involving a rapidly formed antiparallel intermediate were observed with oligonucleo
181 ew solid-state NMR constraints that indicate antiparallel intermolecular alignment of beta-strands wi
183 on of push-pull fluorophores originates from antiparallel ion pair-pi attraction to their polarized e
184 he excited state; i.e., parallel rather than antiparallel ion pair-pi interactions are preferred, des
185 l predictions, we find that parallel but not antiparallel ionpair-pi interactions afford operational
186 ization, stability, and motor composition of antiparallel ipMTs at the midzone, thereby facilitating
192 e, involving fusion domains associated in an antiparallel manner to form an intermolecular beta-sheet
193 binds the tandem WW domain polypeptide in an antiparallel manner, that is, the WW1 domain binds the s
194 on nearly the same timescale as formation of antiparallel melittin dimers, about 6 to 9 ms for 0.3 mM
196 alpha and beta preferentially inhibit XCTK2 antiparallel microtubule cross-linking and sliding by de
197 c, microtubule-independent enrichment of the antiparallel microtubule crosslinker Prc1 at kinetochore
198 zone bundle formation results from promoting antiparallel microtubule crosslinking, stopping microtub
199 rd the cell's apex and base with a region of antiparallel microtubule overlap at the cell's midzone.
201 the motion of Xklp1 motors on reconstituted antiparallel microtubule overlaps demonstrated that moto
202 e enables them to cross-link and slide apart antiparallel microtubules (MTs) emanating from the oppos
206 ic motor protein, can push apart overlapping antiparallel microtubules to generate a force whose magn
207 fferential is low on parallel and extreme on antiparallel microtubules where one motor domain pair be
208 rallel microtubules at the spindle poles and antiparallel microtubules within the spindle midzone to
213 novel CaM-binding motif, binds to CaM in an antiparallel mode with the N-terminal helix (alpha1) anc
215 oms, which are only partially compensated by antiparallel moments of 1.53(14)-3.26(5) mu(B) on the 3
217 the central beta-hairpin coordinated with an antiparallel motion of the C-terminal helix, which may a
218 used here was to fix the orientation of two antiparallel MRAP molecules and then introduce inactivat
219 vestigated the contribution of the midzonal, antiparallel MT-cross-linking nonmotor MAP, Feo, to this
220 gulator of cytokinesis 1), which cross-links antiparallel MTs and is essential for the completion of
221 associated with MTs may cross-link and slide antiparallel MTs emanating from the two nuclei, whereas
222 preferentially cross-links and slides apart antiparallel MTs while the MT plus ends exhibit dynamic
224 We reveal the solution structure of a short, antiparallel, myosin-10 coiled-coil fused to the paralle
225 c transport properties of colloidal beads in antiparallel networks of overlapping actin filaments.
227 short loops two parallel NHR helices and an antiparallel one with the inverse sequence followed by e
228 e parallel configuration with respect to the antiparallel one, while the behaviour of the force patte
229 AtFH14 bundles actin filaments randomly into antiparallel or parallel spindle-like structures; howeve
230 etal filaments assemble into dense parallel, antiparallel, or disordered networks, providing a comple
231 te residues and the FimA core and not by the antiparallel orientation of the donor strand alone.
232 eudo-palindromic sequence, is inserted in an antiparallel orientation relative to the last beta-stran
233 with the Nte inserted in the pilus rod-like, antiparallel orientation, only depends on the identity o
238 oth SIM2 and SIM3 bind SUMO3 in parallel and antiparallel orientations and identified main interactio
241 ties in protein aggregation diseases contain antiparallel, out-of-register beta-sheet structures and
243 of links, presumably alpha-actinin, linking antiparallel overlapping ends of the actin filaments fro
250 nts and theoretical calculations point to an antiparallel pi-stacking interaction as the most stable
251 in-5 both preferentially cross-link MTs into antiparallel polarity patterns, kinesin-5 cannot substit
253 rientation is more stable; both parallel and antiparallel protonated d(GA+A).d(GAA):d(TTC) triplexes
254 witch involves the conversion of alternative antiparallel quadruplex structures binding only one cati
255 s primarily remove Gh from Na(+)-coordinated antiparallel quadruplexes but not K(+)-coordinated paral
257 bacteria is mediated by homology across the antiparallel recombinase-specific recognition sites pres
258 es from one to over 100 and suggest distinct antiparallel registries for interprotofibril association
265 ipole moment, consistent with the contracted antiparallel solid-state pi-pi stacking distances of 8.6
267 he condensation of electrons into pairs with antiparallel spins in a singlet state with an s-wave sym
269 moments with spatial orientations that favor antiparallel stacking and whose structure allows the res
270 as well as electrostatic interactions in the antiparallel stacking mode were first utilized to obtain
271 d(TAGGGTTA) tetraplex to give the first such antiparallel strand assembly in which syn-guanosine is a
274 ruplex structures with parallel, hybrid, and antiparallel strand orientations depending on the temper
275 placement at non-H-bonding positions across antiparallel strands has proven useful for achieving ful
276 of domain atrophy through deletion of 2 core antiparallel strands, resulting in the loss of an entire
278 hanges of telomeric DNA G-quadruplexes to an antiparallel structure (as determined by circular dichro
279 of the human telomeric G-quadruplexes to an antiparallel structure and that this conformational chan
280 parallel arrangement and one of the possible antiparallel structures (with Asp(15) and Phe(19) aligne
281 own to bind preferentially to hybrid than to antiparallel structures, and L2H2-6M(2)OTD, known not to
282 emical basis for F(-) permeation and how the antiparallel subunits convene to form a F(-)-selective p
283 tail-folded antiparallel dimers, tail-folded antiparallel tetramers, unfolded bipolar tetramers, and
285 etization (FDy) has a natural tendency to be antiparallel to Fe(3+) sublattice magnetization (FFe) wi
287 nder the icosahedral 2-fold axis rather than antiparallel to the betaB strand, eliminating many intra
288 etrotransposons for the first time, oriented antiparallel to the coding strand of L1 open reading fra
291 ore of the protease domain undergoes a major antiparallel-to-parallel conformational transition.
292 A first switch is based on a remarkable antiparallel-to-parallel conversion, taking place in a f
297 imicrobial peptides within the unit cell: an antiparallel trimer, which we suggest might be related t
299 arallel-stranded homo-base paired duplex and antiparallel unimolecular hairpin in a pH-dependent mann
300 angular momentum, aligned either parallel or antiparallel with their linear momentum, labelled as lef