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1 nal induction therapy (basiliximab or rabbit antithymocyte globulin).
2 id irradiation, cyclophosphamide, and rabbit-antithymocyte globulin.
3 were mostly cyclophosphamide with or without antithymocyte globulin.
4 ther 20 mg alemtuzumab or 6 mg per kg rabbit antithymocyte globulin.
5 men included busulfan, cyclophosphamide, and antithymocyte globulin.
6 nsity conditioning with cyclophosphamide and antithymocyte globulin.
7 ablative dosages of busulfan, melphalan, and antithymocyte globulin.
8 0 mg/kg cyclophosphamide and 90 mg/kg equine antithymocyte globulin.
9 mg/kg cyclophosphamide, and 90 mg/kg equine antithymocyte globulin.
10 isting of cyclophosphamide, fludarabine, and antithymocyte globulin.
11 1 g methylprednisolone, and 90 mg/kg equine antithymocyte globulin.
12 myelodysplasia, or renal allografts received antithymocyte globulin.
13 renal allograft recipients who had received antithymocyte globulin.
14 grade 2A rejection successfully treated with antithymocyte globulin.
15 duced-intensity conditioning, and the use of antithymocyte globulin.
16 leukocyte antigen mismatch, age, and use of antithymocyte globulin.
17 mib, methylprednisone, rituximab, and rabbit antithymocyte globulin.
18 imus, mycophenolate mofetil, prednisone, and antithymocyte globulins.
19 uccessful induction therapy using two rabbit antithymocyte globulins.
20 ate mofetil, prednisone, and, for induction, antithymocyte globulins.
22 e randomly assigned to receive either rabbit antithymocyte globulin (1.5 mg per kilogram of body weig
23 e the murine monoclonal anti-CD3 antibody or antithymocyte globulin (15.2% versus 21.1%; P=0.061).
26 emental thymic irradiation (7 Gy on day -1), antithymocyte globulin (50 mg/kg on days -2, -1, and 0),
27 along with cyclophosphamide (200 mg/kg) and antithymocyte globulin (6 mg/kg) (n = 55) or DMT of high
28 nditioning regimen used was CYC (200 mg/kg), antithymocyte globulin (90 mg/kg), and methylprednisolon
29 gimen included cyclophosphamide (200 mg/kg), antithymocyte globulin (90 mg/kg), and, for 1 patient, t
32 one dose of 30 mg, in 70 patients) or rabbit antithymocyte globulin (a total of 6 mg per kilogram of
33 ession, all patients received induction with antithymocyte globulin, a brief taper of intravenous sol
34 time, delayed graft function, induction with antithymocyte globulins, acute rejection before month 3
36 f haploidentical marrow grafts, who received antithymocyte globulin after bone marrow transplantation
37 ng regimen of total lymphoid irradiation and antithymocyte globulin allowed engraftment of the donor'
38 tion, the ATG group (13 recipients) received antithymocyte globulin, although the LOCD2b group (10 re
39 teroid withdrawal protocol; 9 of 11 received antithymocyte globulin and 2 received basiliximab induct
41 included induction with a steroid taper and antithymocyte globulin and anti-CD20 monoclonal antibody
42 national study, we compared short courses of antithymocyte globulin and basiliximab in patients at hi
43 ransplantation, immunosuppression (generally antithymocyte globulin and ciclosporin), and high-dose c
44 st-line immunosuppressive therapy (IST) with antithymocyte globulin and cyclosporin and is manifested
45 immunosuppressive therapy with drugs such as antithymocyte globulin and cyclosporine have clonal expa
46 nts with severe aplastic anemia treated with antithymocyte globulin and cyclosporine have durable rec
49 ined a well-established adult mouse model of antithymocyte globulin and DBM treatment and show that e
50 let Transplantation 07 (CIT07) protocol uses antithymocyte globulin and etanercept induction, islet c
51 re less than 150 and 250, respectively, with antithymocyte globulin and intravenous immunoglobulin in
53 received additional immune suppression with antithymocyte globulin and methylprednisolone in the ear
54 sisted of high-dose cyclophosphamide, equine antithymocyte globulin and pretransplant thymic irradiat
56 , contributes to the therapeutic efficacy of antithymocyte globulin and suggest that time-dependent w
61 n posttransplant total lymphoid irradiation, antithymocyte globulin, and a single infusion of ACI per
62 I and thymic irradiation, pretransplantation antithymocyte globulin, and immunoadsorption of anti-Gal
63 total body irradiation, thymic irradiation, antithymocyte globulin, and peritransplant CD154 blockad
64 multivariable analysis, CMV-CMI, sex, race, antithymocyte globulin, and steroid use were independent
67 rapy agents, growth factor combinations, and antithymocyte globulin appear promising and are reviewed
68 ition of melphalan, and the incorporation of antithymocyte globulin appear to have contributed to bet
69 eroid maintenance therapy and induction with antithymocyte globulin are independent risk factors for
70 tion therapy consisting of a 5-day course of antithymocyte globulin, as compared with basiliximab, re
71 CMV disease, attributable to high levels of antithymocyte globulin at the time of T cell infusion.
72 groups based on induction immunosuppression: antithymocyte globulin (ATG) (n=85) or basiliximab (n=29
75 otal body irradiation, cyclophosphamide, and antithymocyte globulin (ATG) and was followed by transpl
77 ate similar to that with regimens containing antithymocyte globulin (ATG) but neither relapse nor clo
80 C using total lymphoid irradiation (TLI) and antithymocyte globulin (ATG) followed by the infusion of
81 ndomized clinical trial comparing ABX-CBL to antithymocyte globulin (ATG) for treatment of steroid-re
87 ences were not seen among patients receiving antithymocyte globulin (ATG) induction (aRR for AR, 1.16
88 rawal after liver transplantation (LT) using antithymocyte globulin (ATG) induction and rapamycin.
93 udies and pilot clinical trials suggest that antithymocyte globulin (ATG) might be effective for redu
94 ersial, particularly regarding concerns that antithymocyte globulin (ATG) might increase HCV-related
96 We studied the impact of early, late, and no antithymocyte globulin (ATG) on immune reconstitution an
98 iated with a clinically relevant response to antithymocyte globulin (ATG) or cyclosporine immunosuppr
99 tion or in vivo T-cell depletion with either antithymocyte globulin (ATG) or monoclonal anti-T-cell a
104 ddition of low, nondepleting doses of rabbit antithymocyte globulin (ATG) to human peripheral blood m
105 ) with T-cell depletion of the donor marrow, antithymocyte globulin (ATG) use, and unrelated or HLA-m
106 ith an NMA preparative regimen that included antithymocyte globulin (ATG) versus those that did not (
107 ed with total lymphoid irradiation (TLI) and antithymocyte globulin (ATG) were given kidney transplan
108 data support replacing BuCy2 with or without antithymocyte globulin (ATG) with Bu-Flu with or without
109 e fraction total body irradiation (TBI), and antithymocyte globulin (ATG) with or without fludarabine
110 ant total lymphoid irradiation (TLI), rabbit antithymocyte globulin (ATG), and a single donor blood t
111 ed the ability of the immune-depleting agent antithymocyte globulin (ATG), as well as the mobilizatio
112 erapy and 93 (>25, 386; n=3) days with added antithymocyte globulin (ATG), but did not yield toleranc
113 oning regimen--whole body irradiation (WBI), antithymocyte globulin (ATG), extracorporeal immunoadsor
114 ive nonmyeloablative protocols using TLI and antithymocyte globulin (ATG), followed by allogeneic hem
115 se using various combinations of four drugs: antithymocyte globulin (ATG), granulocyte-colony stimula
116 -lymphoid irradiation (TLI), with or without antithymocyte globulin (ATG), have been shown to develop
118 s, induction with antilymphocyte globulin or antithymocyte globulin (ATG), or use of ATG or OKT3 for
119 nts receiving total body irradiation without antithymocyte globulin (ATG), whereas the relapse risk w
120 tosus, conditioned with a regimen containing antithymocyte globulin (ATG), who developed factor VIII
121 al greater than 80 days using a steroid-free antithymocyte globulin (ATG)-based induction regimen (AT
122 res of 12 patients with MDS before and after antithymocyte globulin (ATG)-based treatment by T-cell r
123 he cardiovascular consequences of polyclonal antithymocyte globulin (ATG)-induced immune modification
127 Patients received immunosuppression with antithymocyte globulin (ATG)/cyclosporine (CsA) or cyclo
128 experience using dual-induction therapy with antithymocyte globulin (ATG)/daclizumab (Dac) (each with
129 ody irradiation (TBI) required when added to antithymocyte globulin (ATG, 30 mg/kg x 3) plus cyclopho
130 clophosphamide (200 mg/kg) and either equine antithymocyte globulin (ATG, 90 mg/kg) or rabbit ATG (6
131 de (200 mg/kg), methylprednisolone (4 g) and antithymocyte globulin (ATG; 90 mg/kg) or myeloablative
132 s according to whether conditioning included antithymocyte globulin (ATG; n = 191) or alemtuzumab (n
133 splantation either with (n = 241) or without antithymocyte globulin (ATG; n = 491) following reduced-
134 003 to 2004 received no induction (n=4,364), antithymocyte globulin (ATG; n=4,930), interleukin-2 rec
135 orin (CSA) alone or the combination of horse antithymocyte globulin ([ATG] Lymphoglobuline; Merieux,
136 otal body irradiation, cyclophosphamide, and antithymocyte globulin [ATG] with cyclosporine A and met
137 Polyclonal antihuman thymocyte rabbit IgGs (antithymocyte globulin [ATG]) are popular immunosuppress
138 (ATS) (the murine preclinical equivalent of antithymocyte globulin [ATG]) facilitates immune toleran
140 omes after in vivo T-cell depletion (n = 584 antithymocyte globulin [ATG]; n = 213 alemtuzumab) were
141 r patients who have undergone thymoglobulin (antithymocyte globulins [ATG]) or basiliximab (BSX) ther
142 t and 19 lung transplant recipients received antithymocyte globulin (ATGAM or thymoglobulin) as induc
147 reatment study, 34% of patients treated with antithymocyte globulin became transfusion independent.
148 ymic irradiation before transplantation, and antithymocyte globulin before and after transplantation.
150 ome received busulfan, cyclophosphamide, and antithymocyte globulin before receiving cord-blood trans
151 prophylaxis, all but 2 received serotherapy (antithymocyte globulin) before HSCT and a short course o
152 splant recipients who were prescribed rabbit antithymocyte globulin, calcineurin inhibitor, mycopheno
154 t recipients who received induction doses of antithymocyte globulin combined with maintenance immunot
155 (700 cGy) irradiation, T cell depletion with antithymocyte globulin, complement depletion with cobra
156 alemtuzumab-based conditioning with standard antithymocyte globulin conditioning regimens, lower rate
157 er ex vivo nor in vivo T-cell depletion (eg, antithymocyte globulin) convincingly improved outcomes.
158 d elimination at 1 week, and combined rabbit antithymocyte globulin/daclizumab induction, previously
160 A regimen of total lymphoid irradiation plus antithymocyte globulin decreases the incidence of acute
162 total body irradiation, thymic irradiation, antithymocyte globulin, donor bone marrow transplantatio
163 Ganciclovir-resistant patients received more antithymocyte globulin during induction (70+/-44 vs. 45+
168 herefore tested T-cell depletion with rabbit antithymocyte globulin followed by sirolimus monotherapy
169 otal lymphoid irradiation (80 cGy each) plus antithymocyte globulin, followed by an infusion of HLA-m
171 h anti-T-lymphocyte globulin (ATLG; formerly antithymocyte globulin-Fresenius) reduces chronic graft-
176 ic CMVIG and induction with high-dose rabbit antithymocyte globulin (>10 mg/kg) were associated with
177 m immunosuppressive therapy (IST) with horse antithymocyte globulin (h-ATG) and cyclosporine (CsA) ca
178 r between the two groups, patients receiving antithymocyte globulin had a greater incidence of infect
181 re acute rejection resistant to steroids and antithymocyte globulin, histologic evidence of plasma ce
182 arly phase of allogeneic HCT were receipt of antithymocyte globulin (HR, 22.77 [95% CI, 4.85-101.34])
183 nce interval [CI]=1.16-1.81), induction with antithymocyte globulin (HR: 1.43, 95% CI=1.075-1.94), an
185 ired steroid therapy and one required rabbit antithymocyte globulin in addition to MMF and steroids.
187 onmyeloablative conditioning, and absence of antithymocyte globulin in the conditioning regimen.
189 results demonstrate that in a murine system, antithymocyte globulin induces cells with suppressive ac
190 ere enrolled in a prospective study in which antithymocyte globulin induction and 6 days of corticost
191 uired in SPK transplant recipients receiving antithymocyte globulin induction and maintenance immuno-
193 ients of intraportal islet cell grafts under antithymocyte globulin induction and mycophenolate mofet
194 ntenance prednisone in the setting of rabbit antithymocyte globulin induction and tacrolimus and siro
197 ined PAK (n=47) transplants receiving rabbit antithymocyte globulin induction from June 1998 to June
198 CI], 1.2 to 6.6; P=0.02) and those receiving antithymocyte globulin induction therapy (hazard ratio,
199 nor, thin ureters at kidney transplantation, antithymocyte globulin induction therapy, blood transfus
200 An early steroid withdrawal regimen with antithymocyte globulin induction was associated with exc
201 od II (post-August 2001) with alemtuzumab or antithymocyte globulin induction with steroid avoidance.
202 k renal transplant patients usually involves antithymocyte globulin induction with triple drug mainte
203 corticosteroid withdrawal regimen of rabbit antithymocyte globulin induction, tacrolimus, and mycoph
204 pression consisted of quadruple therapy with antithymocyte globulin induction, tacrolimus, MMF, and p
205 corticosteroid withdrawal regimen of rabbit antithymocyte globulin induction, tacrolimus, mycophenol
208 tient received methylprednisolone and rabbit antithymocyte globulin intravenously during scalp prepar
212 CMVIG and appropriate induction with rabbit antithymocyte globulin may be important to reduce CMV in
213 1997 using a similar induction protocol with antithymocyte globulin, mycophenolate mofetil, prednison
217 Thus, in both murine and human systems, antithymocyte globulins not only deplete T cells, but al
218 vidualized conditioning and serotherapy (eg, antithymocyte globulin), nutritional status, exercise, h
219 erapy with Minnesota antilymphocyte globulin/antithymocyte globulin/OKT3 in most cases and maintenanc
220 nt pretreatment with a single dose of rabbit antithymocyte globulin or alemtuzumab and posttransplant
223 n the recipient are depleted by a polyclonal antithymocyte globulin or an anti-T cell immunotoxin.
224 fetil were required as well as either rabbit antithymocyte globulin or interleukin-2 receptor antibod
225 fractory cases, alternative regimens such as antithymocyte globulin or monoclonal antibody therapy ha
227 unosuppressive regimens that included rabbit antithymocyte globulin or tacrolimus/mycophenolate combi
228 hosphamide, and 6.5 mg/kg intravenous rabbit antithymocyte globulin or to receive 1.0 g/m(2) intraven
229 umab (versus no induction, anti-CD25, rabbit antithymocyte globulin, or rabbit antithymocyte globulin
230 (P = 0.046) as well as those having received antithymocyte globulin (P < 0.001) were more likely to d
231 LA-DR mismatches (P = 0.008), induction with antithymocyte globulin (P = 0.0001), and pretransplant p
233 le body and thymic irradiation, splenectomy, antithymocyte globulin, pharmacologic immunosuppression
234 should be considered for a second course of antithymocyte globulin plus cyclosporin, although respon
235 enrolled in immunosuppression protocols with antithymocyte globulin plus cyclosporine for correlation
238 mber 2008 who received induction with rabbit-antithymocyte globulin (r-ATG), alemtuzumab, or an inter
239 ategories: no-induction, alemtuzumab, rabbit antithymocyte globulin (r-ATG), and interleukin-2 recept
240 randomized for 3 different regimens: rabbit antithymocyte globulin (r-ATG)/EVR (N = 85); basiliximab
242 we generated 1:1 pairs of alemtuzumab-rabbit antithymocyte globulin (rATG) (5330 pairs) and basilixim
243 ts were treated with T cell-depleting rabbit antithymocyte globulin (rATG) (6 mg/kg, n = 17) or nonde
244 emtuzumab induction was compared with rabbit antithymocyte globulin (rATG) (Thymoglobulin [Genzyme] o
245 ategies have not been established for rabbit antithymocyte globulin (rATG) after heart transplantatio
247 reatment using induction therapy with rabbit antithymocyte globulin (RATG) and intravenous immunoglob
250 safety and efficacy of induction with rabbit antithymocyte globulin (RATG) compared with interleukin-
251 ients who received either steroids or rabbit antithymocyte globulin (RATG) for orthotopic liver trans
252 recipients who received rituximab and rabbit antithymocyte globulin (rATG) in combination as inductio
253 free immunosuppression protocol using rabbit antithymocyte globulin (RATG) induction in orthotopic li
256 ge, we developed a protocol to extend rabbit antithymocyte globulin (rATG) induction therapy into the
257 5 mg versus MMF in patients receiving rabbit antithymocyte globulin (rATG) induction, mainly due to i
258 ers comparing a control group of with rabbit antithymocyte globulin (rATG) induction, rapid steroid t
260 who were randomized to receive either rabbit antithymocyte globulin (RATG) or steroids as induction t
261 ere evaluated before and after adding rabbit antithymocyte globulin (rATG) to mixed lymphocyte co-cul
263 single-dose (SD) versus divided-dose rabbit antithymocyte globulin (rATG), and a maintenance arm (pa
265 man leukocyte antigen (HLA) mismatch, rabbit antithymocyte globulin (RATG), interleukin-2 receptor an
266 proliferation by Ki-67(+) T cells in rabbit antithymocyte globulin (rATG)-treated patients the first
268 exposed (4.23%) versus not exposed to rabbit antithymocyte globulin (rATG; 0.53%; P=0.019) or SPK (9.
269 iximab (1998), daclizumab (1998), and rabbit antithymocyte globulin (rATG; 1999) replaced antilymphoc
270 ognostic influence of induction type: rabbit antithymocyte globulin (rATG; 2 mg/kg x 5)/rituximab (15
271 ed to assess clinical experience with rabbit antithymocyte globulin (rATG; Thymoglobulin) in living d
274 efine the efficacy of a busulfan/fludarabine/antithymocyte globulin RIC regimen in pediatric patients
275 and consecutive LT patients receiving rabbit antithymocyte globulin+/-rituximab induction were studie
277 25, rabbit antithymocyte globulin, or rabbit antithymocyte globulin/rituximab) induction (P = 0.004),
278 tion of donor marrow (RR = 12.7), and use of antithymocyte globulin (RR = 6.4) or anti-CD3 monoclonal
280 as carried out under Tac-Pred in six, rabbit antithymocyte globulin-Tac in eight, and alemtuzumab mon
282 itioning with total lymphoid irradiation and antithymocyte globulin, the fraction of donor CD4+ T cel
284 ipheral CD3 lymphocytes to rationally adjust antithymocyte globulin therapy in this patient populatio
286 imary kidney transplant recipients comparing antithymocyte globulin (Thymoglobulin) (group A, N=43) v
287 eatment with approximately 5 mg/kg of rabbit antithymocyte globulin (Thymoglobulin) in the hours befo
288 Recipients were treated with 7 doses of antithymocyte globulin (Thymoglobulin, day 1 to 9), siro
289 omized, international study comparing rabbit antithymocyte globulin (TMG) and basiliximab (BAS) induc
290 rotocol applied including plasmapheresis and antithymocyte globulin treatment as well as cyclophospha
291 th or without endarteritis responded to OKT3/antithymocyte globulin treatment equally well (61% versu
293 the patients) was defined as requirement for antithymocyte globulin treatment within 2 weeks after co
295 with Aspergillus colonization, use of rabbit antithymocyte globulin was associated with 4-fold risk o
296 -2-receptor induction with daclizumab versus antithymocyte globulin was independently associated with
297 ortional hazard model, treatment with rabbit antithymocyte globulin was significantly associated with
300 nduction therapy (antilymphocyte globulin or antithymocyte globulin), whereas LRD recipients did not.