ライフサイエンスコーパス: anxiety disorder

1 ostic criteria for depression or generalised anxiety disorder.

2 onstitute a predominant preclinical model of anxiety disorder.

3 sm spectrum symptoms, and the presence of an anxiety disorder.

4 rments during decision making in generalized anxiety disorder.

5 d reinforcement) is disrupted in generalized anxiety disorder.

6 s a potent risk factor for development of an anxiety disorder.

7 tests are common preclinical models of human anxiety disorder.

8 disorders, with the exception of separation anxiety disorder.

9 assessed, including 93 participants with an anxiety disorder.

10 al, but also psychiatric, disorders, such as anxiety disorder.

11 ntal mechanisms that may be disturbed in the anxiety disorder.

12 BI do not go on to meet criteria for social anxiety disorder.

13 ain-based targets for treatment of pediatric anxiety disorders.

14 has the potential to inform the treatment of anxiety disorders.

15 ep disruption is a recognized feature of all anxiety disorders.

16 personality trait that is a risk factor for anxiety disorders.

17 lausible source of dysfunction in stress and anxiety disorders.

18 risk factor for the development of mood and anxiety disorders.

19 therapeutic targets in major depression and anxiety disorders.

20 is a precipitating factor in depression and anxiety disorders.

21 individuals suffering from a mix of mood and anxiety disorders.

22 contribute to increased fear associated with anxiety disorders.

23 nectivity is a pathophysiological feature of anxiety disorders.

24 is a potential target for new treatments of anxiety disorders.

25 ized fear responses that are associated with anxiety disorders.

26 closely associated with the pathogenesis of anxiety disorders.

27 safety learning are key features of fear and anxiety disorders.

28 gery and as a possible approach for treating anxiety disorders.

29 echanism of nonspecific fear associated with anxiety disorders.

30 sk factor for adult psychopathology, such as anxiety disorders.

31 prefrontal with limbic regions, in boys with anxiety disorders.

32 of the OFC in mediating specific symptoms of anxiety disorders.

33 their dysregulation may be at the origin of anxiety disorders.

34 egulation is successful in treating mood and anxiety disorders.

35 unipolar depression, bipolar depression, and anxiety disorders.

36 asciculus in unmedicated boys and girls with anxiety disorders.

37 iculus white matter alterations in boys with anxiety disorders.

38 al connectivity within regions implicated in anxiety disorders.

39 goals of therapeutic interventions in human anxiety disorders.

40 ole of Asb1-mediated immune dysregulation in anxiety disorders.

41 ry features of these treatments in pediatric anxiety disorders.

42 iterature on Pavlovian learning in pediatric anxiety disorders.

43 a potential target for reducing avoidance in anxiety disorders.

44 has been implicated anxiogenic behaviors and anxiety disorders.

45 al for formulating successful treatments for anxiety disorders.

46 on is likely to contribute to depression and anxiety disorders.

47 ERN is not entirely static in patients with anxiety disorders.

48 ogical organisms, and a laboratory model for anxiety disorders.

49 goals of therapeutic interventions in human anxiety disorders.

50 vel mechanism of action for the treatment of anxiety disorders.

51 c properties and is reduced in patients with anxiety disorders.

52 ed on connections between manic episodes and anxiety disorders.

53 rapy (CBT) and pharmacotherapy for childhood anxiety disorders.

54 for the treatment and prevention of mood and anxiety disorders.

55 mygdala are implicated in the development of anxiety disorders.

56 shed light on the pathogenesis of underlying anxiety disorders.

57 2 included 55 children and adolescents with anxiety disorders.

58 sent a novel therapeutic target for fear and anxiety disorders.

59 o therapeutics for children with early onset anxiety disorders.

60 ogy, maintenance, and treatment of pediatric anxiety disorders.

61 ide insight into novel treatment targets for anxiety disorders.

62 uld serve as potential treatment targets for anxiety disorders.

63 nstrated associations with risk for mood and anxiety disorders.

64 enhancing treatment outcomes for youths with anxiety disorders.

65 behavior is a defining feature of pediatric anxiety disorders.

66 in two independent samples of patients with anxiety disorders.

67 dolescent adversity increases adult risk for anxiety disorders.

68 terventions for sleep impairment in mood and anxiety disorders.

69 hood of developing psychopathologies such as anxiety disorders.

70 y discrimination is a hallmark of stress and anxiety disorders.

71 ment and prevention strategies for pediatric anxiety disorders.

72 increases the risk for adult depression and anxiety disorders.

73 be reduced is at the heart of treatments for anxiety disorders.

74 as a contributory factor in the etiology of anxiety disorders.

75 n marmoset, similar to that seen in mood and anxiety disorders?

76 69, 0.63-0.75 in South London and Maudsley), anxiety disorders (0.81, 0.69-0.96 in Camden and Islingt

77 icit hyperactivity disorder; 20% (17-23) for anxiety disorders; 13% (9-17) for sleep-wake disorders;

78 rders (19.5% [CI, 18.0% to 21.0%] vs. 8.1%), anxiety disorders (19.5% [CI, 18.0% to 21.0%] vs. 11.1%)

79 r anxiety (based on score on the Generalized Anxiety Disorder 2-item scale [GAD-2], N=199,611) as the

80 ent Health Questionnaire and the Generalized Anxiety Disorder-2 Scale, respectively.

81 mmon psychiatric diagnoses at the visit were anxiety disorders (20.0%), major depressive disorder (16

82 (Hopkins symptom check list-25, Generalized anxiety disorder 7 questionnaire, and Beck's Depression

83 9-item depression scale, and the Generalized Anxiety Disorder 7-item scale.

84 lth Questionnaire-9 (PHQ-9), the Generalised Anxiety Disorder-7 (GAD-7) questionnaire, and 12-Item Sh

85 on, with anxiety measured by the Generalized Anxiety Disorder-7 and depression measured by the Patien

86 uestionnaire-Mizan (LSEQ-M), the Generalized Anxiety Disorder-7 Scale (GAD-7), and the Sleep Hygiene

87 Patient Health Questionnaire-9, Generalised Anxiety Disorder-7 scale, Alcohol Use Disorder Identific

88 st-injury to screen for anxiety (generalized anxiety disorder-7), depression (patient health question

89 effective treatment choices for generalised anxiety disorder across classes of medication.

90 external threats is a key factor in mood and anxiety disorder aetiology.

91 Anxiety disorders affect approximately 1 in 5 (18%) Amer

92 we found that men with depressive disorder, anxiety disorder, alcohol use disorder, drug use disorde

93 six unmedicated individuals with generalized anxiety disorder and 32 healthy comparison subjects grou

94 dividuals (3 male subjects) with generalized anxiety disorder and assessed its effects on neural resp

95 le, 1 transgender, 2 undeclared) with social anxiety disorder and fear of public speaking were random

96 psychiatric disorders, including generalized anxiety disorder and posttraumatic stress disorder.

97 emotion regulation disorders, such as social-anxiety disorder and psychopathy.

98 Patients with history of anxiety disorder and those presenting acute stress sympt

99 ve explanatory account of the development of anxiety disorders and addiction, but such models also fa

100 y was to examine the genetic architecture of anxiety disorders and anxiety symptoms, which are also f

101 iences during childhood increase the risk of anxiety disorders and attention-deficit/hyperactivity di

102 s are more likely to develop PTSD, mood, and anxiety disorders and demonstrate endocrine and molecula

103 on circuitry and a higher risk of developing anxiety disorders and depression.

104 guide new treatment strategies for childhood anxiety disorders and further support the use of nonhuma

105 odels of information processing in pediatric anxiety disorders and highlight the particular value of

106 al neurobiology of behavioral inhibition and anxiety disorders and may aid in early risk assessment a

107 increased risk for the later development of anxiety disorders and other stress-related psychopatholo

108 therapies for those suffering from mood and anxiety disorders and provide insight into addiction.

109 eports of burnout, musculoskeletal injuries, anxiety disorders and sleep disturbances compared to les

110 outcomes including musculoskeletal injuries, anxiety disorders and sleep disturbances.

111 Study 1 consisted of 81 adults with anxiety disorders and Study 2 included 55 children and a

112 eCB-based treatment approaches for mood and anxiety disorders and suggest a potentially wider therap

113 cinate fasciculus FA exists in children with anxiety disorders and the extent to which this alteratio

114 Because of the early onset of anxiety disorders and the increased incidence in anxiety

115 ility, autism spectrum disorder, generalized anxiety disorder, and a >40-fold increased risk for schi

116 schizophrenia, bipolar disorder, depression, anxiety disorders, and attention-deficit/hyperactivity d

117 al health issues including fatigue, mood and anxiety disorders, and cognitive impairments.

118 -mGluR5 axis is linked to Parkinson disease, anxiety disorders, and drug addiction.

119 ding, but not limited to, Parkinson disease, anxiety disorders, and drug addiction.

120 spectrum disorder, substance use disorders, anxiety disorders, and personality disorders.

121 depressive disorder (MDD), bipolar disorder, anxiety disorders, and schizophrenia.

122 In nonfatal suicidal behaviour, anxiety disorders, and substance misuse were identified

123 hizophrenia, bipolar or unipolar depression, anxiety disorders, and substance use disorders).

124 7; 95% confidence interval: 1.3-2.2) and any anxiety disorder (AOR: 1.8; 1.4-2.2), although not of su

125 Major depression and anxiety disorders are a social and economic burden world

126 Anxiety disorders are among the most prevalent psychiatr

127 Anxiety disorders are associated with disruptions in bot

128 or time, respectively.SIGNIFICANCE STATEMENT Anxiety disorders are characterized by a common symptom

129 Anxiety disorders are characterized by excessive attenti

130 Many anxiety disorders are characterized by generalization of

131 Anxiety disorders are common and often disabling.

132 Anxiety disorders are common, can result in lifelong suf

133 Anxiety disorders are common, complex psychiatric disord

134 Anxiety disorders are commonly associated with increased

135 Mood and anxiety disorders are complex heterogeneous syndromes th

136 Alcohol use disorder (AUD) and anxiety disorders are frequently comorbid and share mech

137 Animal models of anxiety disorders are important for elucidating neurobio

138 Childhood sleep and anxiety disorders are important predictors, as are clini

139 Anxiety disorders are infrequently recognized during rou

140 Anxiety disorders are the most common form of mental ill

141 Anxiety disorders are the most prevalent psychiatric dis

142 Anxiety disorders are the most prevalent psychiatric dis

143 Major depression and anxiety disorders are treated using selective serotonin

144 balance, which are dysfunctional in mood and anxiety disorders, are insensitive to alterations in are

145 d assessed parenting, child temperament, and anxiety disorders as contributors to the neural developm

146 orphism of the pathophysiology that leads to anxiety disorders, as well as to identify sex-specific e

147 ), generalised anxiety symptoms (Generalised Anxiety Disorder Assessment 7-item version), mental and

148 s improve depressive disorders and symptoms, anxiety disorders, attention-deficit hyperactivity disor

149 a key brain structure implicated in mood and anxiety disorders, based primarily on evidence from corr

150 for the onset of psychiatric disorders, with anxiety disorders being the most common and affecting as

151 were major depressive disorder, generalised anxiety disorder, bipolar disorder, neuroticism, mood in

152 traumatic stress disorder, addiction, social anxiety disorder, bipolar disorder, schizophrenia, and a

153 posure therapy is a first-line treatment for anxiety disorders but remains ineffective in a large pro

154 mpulsive disorder (OCD) and various types of anxiety disorders, but phenomenological overlap, high ra

155 ly involved in the etiology and treatment of anxiety disorders, but positron emission tomography (PET

156 dely used in the treatment of depression and anxiety disorders, but responsiveness is uncertain and s

157 ical agents for the treatment of generalised anxiety disorder by use of network analysis.

158 light the potential to enhance treatment for anxiety disorders by targeting an alternative neural mec

159 rder-relevant neural circuits in generalized anxiety disorder can be beneficially altered through mod

160 more prone to major depressive disorder and anxiety disorders compared to males.

161 y participants and individuals with mood and anxiety disorders completed an approach-avoidance go/no-

162 tely half of whom met criteria for a current anxiety disorder, completed a task measuring involuntary

163 More specifically, in adults with anxiety disorders, decreased fractional anisotropy (FA),

164 those with antisocial personality disorder, anxiety disorders, depressive disorders, and a history o

165 e-contingent music reward therapy for social anxiety disorder designed to reduce attention dwelling o

166 brain systems underlying the early risk for anxiety disorder development.

167 nction recall) and the number of co-occuring anxiety disorders diagnosed (etap2 = 0.137, P = .009 for

168 ility significantly decreased adjustment and anxiety disorder diagnoses among their children.

169 ersity, particularly those who later develop anxiety disorders, display additional engagement of neur

170 being considered as a novel therapeutic for anxiety disorders due to its ability to promote affiliat

171 esent potential options for the treatment of anxiety disorders due to their potent anxiolytic profile

172 n that dysregulated fear levels characterize anxiety disorders, examining the neural correlates of fe

173 Patients with social anxiety disorder exhibit increased attentional dwelling

174 hough both pediatric and adult patients with anxiety disorders exhibit similar neural responding to t

175 thy subjects compared with participants with anxiety disorders exhibited greater amygdala-ventromedia

176 ely adopted as a model system for stress and anxiety disorders, fear-conditioning research has not ye

177 Age moderated two sets of anxiety disorder findings.

178 dwide, is associated with acute anxiety, and anxiety disorders following regular use.

179 ales with a primary diagnosis of generalized anxiety disorder (GAD) and nonpsychiatric controls.

180 or depressive disorder (MDD) and generalized anxiety disorder (GAD) are highly prevalent and debilita

181 ermine whether panic disorder or generalized anxiety disorder (GAD) in pregnancy, or medications used

182 Generalized anxiety disorder (GAD) is a common and disabling illness

183 raumatic stress disorder (PTSD), generalized anxiety disorder (GAD), panic disorder (PD), and phobias

184 Health Questionnaire (PHQ-9) and Generalised Anxiety Disorder (GAD-7) scales were used to assess the

185 nxiety (measured by the two-item Generalised Anxiety Disorder [GAD]-2 anxiety scale), and post-trauma

186 scale), level of anxiety (7-item Generalized Anxiety Disorder; GAD-7), level of depression (9-item Pa

187 luded: posttraumatic stress disorder, social anxiety disorder, generalized anxiety disorder, panic di

188 for full or probable diagnoses of separation anxiety disorder, generalized anxiety disorder, social p

189 individuals with at least 1 of the following anxiety disorders: generalized anxiety disorder, social

190 d PNA were both indicative of depression and anxiety disorders, greater PNA was more strongly related

191 pes.SIGNIFICANCE STATEMENT Predisposition to anxiety disorders has both a neurodevelopmental and a ge

192 ased results demonstrated that children with anxiety disorders have significant reductions in uncinat

193 t six times as likely to have had a mood and anxiety disorder health care visit, more than three time

194 was to ascertain the prevalence of mood and anxiety disorder health care visits and antidepressant a

195 Outcome measures were mood and anxiety disorder health care visits, antidepressant and

196 hment, reoperation within 30 days, dementia, anxiety disorder, hearing difficulty, or history of drug

197 medication-for managing both OCD and non-OCD anxiety disorders in clinical settings.

198 This review examines the phenomenology of anxiety disorders in early life, highlighting developmen

199 ety disorders and the increased incidence in anxiety disorders in females during their reproductive y

200 y data show that maternal panic disorder, or anxiety disorders in general, increase the risk for adve

201 eat and inform the etiology and treatment of anxiety disorders in humans.

202 tment increases the likelihood of developing anxiety disorders in humans.

203 eased rates of major depressive disorder and anxiety disorders in one or more of these conditions.

204 ognitive training interventions in pediatric anxiety disorders in the domains of attention, interpret

205 herapeutic compounds to treat depression and anxiety disorders in women.

206 ay contribute to increased susceptibility to anxiety disorders in women.

207 rs of cognitive control in pediatric OCD and anxiety disorders, including before and after treatment.

208 r older who are not currently diagnosed with anxiety disorders, including pregnant and postpartum wom

209 r older who are not currently diagnosed with anxiety disorders, including pregnant and postpartum wom

210 and adult women not currently diagnosed with anxiety disorders, including pregnant or postpartum wome

211 ty, diabetes/hypertensive disorders, or mood/anxiety disorders, increases the risk for adverse neurod

212 Pediatric anxiety disorders involve greater capture of attention b

213 r treating posttraumatic stress disorder and anxiety disorders involving abnormal memories are emergi

214 Generalised anxiety disorder is a disease that can be associated wit

215 Generalized anxiety disorder is associated with hyperactivity in the

216 relevant for understanding pediatric OCD and anxiety disorders is cognitive control, given the diffic

217 A core feature of anxiety disorders is difficulty regulating fear, with ev

218 A common symptom of anxiety disorders is the overgeneralization of fear acro

219 At the core of anxiety disorders lies the tendency to generalize fear f

220 cohol or tobacco use disorder with past-year anxiety disorders, mood disorders, and posttraumatic str

221 ttentional processing in social anxiety, and anxiety disorders more broadly, have postulated an initi

222 Compared to patients with generalized anxiety disorder (n = 24) and healthy control subjects (

223 a genome-wide association study of Lifetime Anxiety Disorder (n(case) = 25 453, n(control) = 58 113)

224 is and self-report of physician diagnosis of anxiety disorder (N=224,330) as a secondary analysis.

225 M age=25.8+/-8.5; 67% female) with principal anxiety disorders (n=60) or no lifetime history of Axis

226 isruptive mood dysregulation disorder, N=52; anxiety disorder, N=42; attention deficit hyperactivity

227 nxiety disorder, social anxiety disorder, or anxiety disorder not otherwise specified, and 46 were ma

228 der with or without agoraphobia, generalized anxiety disorder, obsessive-compulsive disorder, or soci

229 ns, including posttraumatic stress disorder, anxiety disorders, obsessive-compulsive disorder, and su

230 -environmental reasons why hyperactivity and anxiety disorders occur at higher rates in deaf individu

231 ponse to unpredictable threats, pathological anxiety disorders occur when symptoms adversely affect d

232 feeding and eating disorders, schizophrenia, anxiety disorder, OCD, and most affective disorders also

233 History of anxiety disorder odds ratio = 3.7 (95% CI, 1.24-11.05; p

234 Patients with anxiety disorders often experience a relapse in symptoms

235 onal defiant disorder (OR 3.6, 1.4-9.4), any anxiety disorder (OR 2.9, 1.2-6.7), and autism spectrum

236 isorder, separation anxiety disorder, social anxiety disorder, or anxiety disorder not otherwise spec

237 iety disorder, specific phobias, generalized anxiety disorder, or separation anxiety and who received

238 the 16 patients had comorbid mood disorders, anxiety disorders, or both.

239 matic stress disorder, eating disorders, and anxiety disorders other than specific phobia, and was po

240 diagnosed as having specific phobia, social anxiety disorder, panic disorder with or without agoraph

241 sorder, social anxiety disorder, generalized anxiety disorder, panic disorder, and specific phobia.

242 ug 9, 2017, on the prevalence of depression, anxiety disorder, post-traumatic stress disorder, bipola

243 The data demonstrate that anxiety disorder-related alterations in prefrontal-limbi

244 In addition, individuals with generalized anxiety disorder relative to healthy participants showed

245 uring feedback, individuals with generalized anxiety disorder relative to healthy subjects showed a r

246 cognitive training treatments for pediatric anxiety disorders rely on accurate and reliable identifi

247 ertoire of effective treatments for mood and anxiety disorders represents a critical unmet need.

248 rnalizing conditions of major depression and anxiety disorders, risk was associated with low SA but w

249 Many patients with social anxiety disorder (SAD) experience inadequate symptom rel

250 Cognitive models posit that social anxiety disorder (SAD) is maintained by biased informati

251 ) and dopamine (DAT) in patients with social anxiety disorder (SAD).

252 g to the emergence and maintenance of social anxiety disorder (SAD).

253 nt with JNJ-42165279 in subjects with social anxiety disorder (SAD).

254 ate to high accuracy for adults (Generalized Anxiety Disorder scale: sensitivity, 70% to 97%; specifi

255 e diagnoses: depressive episode, generalised anxiety disorder, schizophrenia, bipolar type 1 disorder

256 activity disorder, autism spectrum disorder, anxiety disorders, seizures and epilepsy, and early-onse

257 ial in patients with anhedonia and a mood or anxiety disorder (selective KOR antagonist (JNJ-67953964

258 (ages 8-12); 52 met criteria for generalized anxiety disorder, separation anxiety disorder, social an

259 Behaviorally, individuals with generalized anxiety disorder showed impaired reinforcement-based dec

260 ightened autonomic drive, as seen in chronic anxiety disorders.SIGNIFICANCE STATEMENT The dialogue be

261 Childhood sleep and anxiety disorders significantly predicted 1.6-fold and 1

262 e show in the current report that only prior anxiety disorders significantly predicted PTSD in a mult

263 for generalized anxiety disorder, separation anxiety disorder, social anxiety disorder, or anxiety di

264 the following anxiety disorders: generalized anxiety disorder, social anxiety disorder, specific phob

265 of separation anxiety disorder, generalized anxiety disorder, social phobia, major depression, dysth

266 orders: generalized anxiety disorder, social anxiety disorder, specific phobia, and panic disorder.

267 onfirmed diagnoses of panic disorder, social anxiety disorder, specific phobias, generalized anxiety

268 Evidence-based interventions for anxiety disorders, such as cognitive behavioral therapy,

269 -onset obsessive-compulsive disorder and the anxiety disorders, suggest a broad and important role fo

270 ight nevertheless be a better model for some anxiety disorders than others.

271 absence of danger is a hallmark of disabling anxiety disorders that affect millions of people.

272 iology for sex differences in stress-related anxiety disorders that warrants further study.

273 depressant effects in patients with mood and anxiety disorders that were previously resistant to trea

274 ic phobia appeared the most, and generalized anxiety disorder the least, similar to induced anxiety.

275 ms between posttraumatic stress disorder and anxiety disorders, the latter has received less attentio

276 ic acid (GABA)) neurotransmitter circuits in anxiety disorders, the stress system has been directly i

277 plicated in sleep impairment and in mood and anxiety disorders: the default mode network and negative

278 similarities in the biological correlates of anxiety disorders, this study identified age differences

279 mechanisms that might contribute to fear and anxiety disorders transmission in clinically affected fa

280 and ayahuasca for the treatment of mood and anxiety disorders, trauma and stress-related disorders,

281 ERN can inform the choice between first-line anxiety disorder treatments and whether the ERN changes

282 medical records, and extracted data on mood/anxiety disorders until childbirth from the Care Registe

283 ctural neuroimaging studies of patients with anxiety disorders utilize adult samples, and the few stu

284 step towards improving our understanding of anxiety disorder vulnerability.

285 n variant heritability estimate for Lifetime Anxiety Disorder was 26%, and for Current Anxiety Sympto

286 1.5% (95% CI 22.64-40.38), the prevalence of anxiety disorders was 11% (95% CI 6.75-15.43), and the p

287 physiology of psychiatric conditions such as anxiety disorders, we know little about how individual d

288 her parental education and having a comorbid anxiety disorder were protective factors.

289 er, obsessive-compulsive disorder, or social anxiety disorder were randomly assigned by principal dia

290 METHOD: Forty patients with social anxiety disorder were randomly assigned to eight session

291 Anxiety disorders were assessed using the Mini-Internati

292 Pre-existing anxiety disorders were associated with more severe sympt

293 Five anxiety disorders were included: posttraumatic stress di

294 Comorbid anxiety disorders were more likely in psychosis spectrum

295 ychiatric disorders including depression and anxiety disorders, which often have a neurodevelopmental

296 nction in youths and adults with and without anxiety disorders while rating fear and memory of ambigu

297 evidence-based psychological treatments for anxiety disorders with less attrition.

298 = 326) included treatment-seeking youth with anxiety disorders, with disruptive mood dysregulation di

299 stigation of vmPFC safety signaling in other anxiety disorders, with potential implications for the d

300 atments is recommended for pediatric OCD and anxiety disorders, young patients often remain symptomat