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1 -containing GABAA receptors, was shown to be anxiolytic.
2 t is maladaptive, excessive, repetitive, and anxiolytic.
3 activation is positively reinforcing and/or anxiolytic.
4 tect the urocortins, which are thought to be anxiolytic.
5 ng that inhibition of AT1R within the SFO is anxiolytic.
6 beta (ERbeta) agonists have been shown to be anxiolytic.
7 CE STATEMENT Within the BLA, NPY is potently anxiolytic.
8 opportunities to exploit PTP1B inhibitors as anxiolytics.
9 is an urgent need to develop novel and safe anxiolytics.
10 iety or prescriptions for antidepressants or anxiolytics.
11 with 3.6 (95% CI, 3.2-4.1) for sedatives and anxiolytics, 2.9 (95% CI, 2.3-3.5) for stimulants, and 2
12 bition of the cmA as a common denominator of anxiolytic action, with only OXT inducing large-scale co
13 h after injury, while it was devoid of clear anxiolytic actions and did not affect water-maze perform
17 tive emotional effects of stress and exerted anxiolytic actions without influencing hypothalamic-pitu
19 to the ventricles exerted antidepressant and anxiolytic activity along with an increase in hippocampa
20 e either striatal and limbic stereotypies or anxiolytic activity, thus outlining their potential to t
22 asingly recognized as an antinociceptive and anxiolytic agent, effects which may be mediated via oxyt
24 this dose shares some effects with existing anxiolytic agents in dampening response to emotional sti
31 evealed that compounds 7a,c,d,l,m,q,r,w show anxiolytic and antiamnestic activities without the unple
33 Cre:gamma2(f/f) mice mimicked the effects of anxiolytic and antidepressant drugs in a number of behav
36 In vivo, both MIA-690 and MR-409 induced anxiolytic and antidepressant-like effects, increased no
38 cretion and has potent anorectic, analgesic, anxiolytic and antidepressive-like effects in animal mod
39 ytocin (OXT) has been revealed as a profound anxiolytic and antistress factor of the brain, besides i
41 levating brain endocannabinoids (eCBs) share anxiolytic and fear extinction-facilitating properties w
42 as generated substantial interest due to its anxiolytic and fear-attenuating effects in rodents, whil
43 hat future work should control carefully for anxiolytic and gender effects, which could underlie inco
44 he possibility of two opposing circuits, one anxiolytic and one anxiogenic, within the BNST, the rela
46 he roots of Valeriana officinalis used as an anxiolytic and sedative and in the treatment of insomnia
51 anti-inflammatories, cardiovascular agents, anxiolytics and human indicators) in seafood samples.
52 oid psychotropics, including antidepressants/anxiolytics and sleep aids) in the 90 days postdiagnosis
58 D) are nowadays addressed by antidepressant, anxiolytic, and antipsychotic drugs, often administered
59 tility and appetite, and produce anticancer, anxiolytic, and neuroprotective efficacies via cannabino
60 e pharmaceuticals (i.e., antischizophrenics, anxiolytics, and antidepressants) in sludge from 40 repr
62 ceived prescriptions for antidepressants and anxiolytics, and more than six times as likely to have b
63 ions for benzodiazepines, Z-drugs, and other anxiolytics, and patients were followed for incident dem
67 Similarly, voluntary wheel running produces anxiolytic- and antidepressant-like effects in rodent mo
68 R subunit in the amygdala all induced robust anxiolytic- and antidepressant-like effects in several m
69 le for estradiol in mediating the protective anxiolytic- and antidepressant-like effects of testoster
70 estradiol pellet, and subsequent protective anxiolytic- and antidepressant-like effects of testoster
71 Enhancing endocannabinoid signaling produces anxiolytic- and antidepressant-like effects, but the neu
74 hether insulin-sensitizing strategies induce anxiolytic- and/or antidepressant-like activities and to
75 sion and are allosterically modulated by the anxiolytic, anticonvulsant, and sedative-hypnotic benzod
76 sized within the brain and act as endogenous anxiolytic, anticonvulsant, hypnotic, and sedative agent
77 important classes of clinical agents (e.g., anxiolytics, anticonvulsants, and general anesthetics) t
78 piandrosterone (DHEA) is a neurosteroid with anxiolytic, antidepressant, and antiglucocorticoid prope
79 with RS67333, similar to fluoxetine, induced anxiolytic/antidepressant-like activity and stimulated a
80 ronic treatment with GR125487 prevented both anxiolytic/antidepressant-like and neurogenic effects of
82 o corticosteroids, opioids, benzodiazepines, anxiolytics, antidepressants, beta-blockers, anaesthetic
83 ed pronounced cannabinoid receptor-dependent anxiolytic, antiinflammatory, and analgesic effects in m
84 e US prescription fills for antidepressants, anxiolytics, antipsychotics, opioids, and antiepileptics
85 task for escape, the elevated plus maze for anxiolytic/anxiogenic effects, place preference conditio
87 accompanied by improvements in cognitive and anxiolytic behavior and the normalization of changes in
89 low-wave oscillations offer an ameliorating, anxiolytic benefit on these brain networks following sle
92 (BNST) inhibitory microcircuit that silences anxiolytic BNST outputs to the ventral tegmental area an
93 ncome adults prescribed an antidepressant or anxiolytic by a primary care or non-MH professional and
94 )R-selective benzodiazepine site agonist and anxiolytic compound TP003 increases tonic currents and d
99 arallel in behaving animals and link them to anxiolytic drug action, novelty, and the metric for self
105 alidity mainly rests on the observation that anxiolytic drugs reduce rodent anxiety-like behavior.
111 molecular underpinnings of the MitoQ-driven anxiolytic effect and found that MitoQ treatment alters
115 receptors in the dBNST is necessary for the anxiolytic effect observed following optogenetic stimula
116 d activation of the rACC correlated with the anxiolytic effect of alprazolam (r(p) = .52; p = .04).
118 or and ongoing stress delays or prevents the anxiolytic effect of exercise without affecting exercise
120 re performed to estimate significance of the anxiolytic effect of lavender essential oil taken as sil
129 etermine whether intranasal OT has a general anxiolytic effect on the performance of rhesus monkeys t
130 ctivation of eEF2 within the PVN conveyed an anxiolytic effect supporting a role of OXT-induced eEF2
141 estigations of individual moderators of OT's anxiolytic effects (i.e. sex, genetic factors, and early
143 intra-mPFC infusion of RS67333 produced fast anxiolytic effects and increased DRN 5-HT cell firing.
144 ed rapid and long-lasting antidepressant and anxiolytic effects and that these effects are associated
147 tivate FGF receptors have antidepressant and anxiolytic effects in animal models, FGF ligands have a
148 ctivity could mediate acute exercise-induced anxiolytic effects in regards to amygdala reactivity, an
151 mice beta-catenin mediates pro-resilient and anxiolytic effects in the nucleus accumbens, a key brain
161 induce protein synthesis, which mediates the anxiolytic effects of OXT within the PVN and suggests th
164 brafish as a model organism for studying the anxiolytic effects of scopolamine, its mechanisms of act
166 FC completely blocked the antidepressant and anxiolytic effects of systemic ketamine in rodent models
170 In addition, exercise has been shown to have anxiolytic effects, further confounding interpretation o
171 ultiple reports of DHEA's antidepressant and anxiolytic effects, no research to date has examined the
172 spectively, has not produced the anticipated anxiolytic effects, our data show that targeted interfer
173 ese findings demonstrate that BHB exerts its anxiolytic effects, possibly by inhibiting systemic TNF-
174 se CT equivalent has positively reinforcing, anxiolytic effects, suggesting a role in grooming and af
194 exposure regimen that did not compromise the anxiolytic efficacy of CDP in control mice, the results
195 exposure to the EPM completed abolishes the anxiolytic efficacy of chlordiazepoxide (CDP; 15 mg/kg)
199 d of anxiety patients remain unresponsive to anxiolytics highlighting the need for more effective, me
201 Lef1 is required for the differentiation of anxiolytic hypothalamic neurons in zebrafish and mice, a
202 that 4 weeks of voluntary wheel running was anxiolytic in C57BL/6J mice and resulted in a shorter ti
203 Similar to humans, scopolamine acted as an anxiolytic in individual behavioural tests (novel approa
206 of 5 mug of DA improved working memory, was anxiolytic in the plus maze, and increased pain sensitiv
207 rcumstances, rather than acting as a general anxiolytic, in a highly translatable nonhuman model, the
210 ce that modulation of alpha5-GABAARs elicits anxiolytic-like actions, whereas our data do not provide
212 a broad antipsychotic-, antidepressant-, and anxiolytic-like activity, not eliciting motor impairment
214 gh affinity value (Ki = 0.27 nM) and for its anxiolytic-like and ability to relieve neuropathic painf
215 GABAA receptor subtype ligands endowed with anxiolytic-like and antihyperalgesic action or enhancer
219 ective agonist, elicited antidepressant- and anxiolytic-like behavioral effects in wild-type mice, wi
220 pal CA1 region displayed antidepressant- and anxiolytic-like behaviors associated with widespread enh
222 RS 67333 was found to produce a paradoxical anxiolytic-like effect similar to that produced by the 5
223 further characterized and exhibited improved anxiolytic-like effects in a mouse marble burying assay
224 oid 2-arachidonoyl-sn-glycerol (2-AG), exert anxiolytic-like effects in rodent models via 2-AG-depend
226 ntion and induced marked antidepressive- and anxiolytic-like effects in socially isolated mice with r
227 generated behavioral profiles indicative of anxiolytic-like effects in the EZM, which was apparent f
228 WH133 (0.3, 1 and 3 mg/kg, IP) also produced anxiolytic-like effects in TMT-stressed rats, which were
229 mplicate the Y(5) receptor in the long-term, anxiolytic-like effects of NPY in the BLA, consistent wi
230 al striatum produced antidepressant-like and anxiolytic-like effects on FST and NSFT respectively.
232 ific effects of THC such as memory deficits, anxiolytic-like effects, and social interaction are unde
234 spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms.
235 The peptide hormone oxytocin (OXT) exhibits anxiolytic-like properties in animals and humans, but wh
237 in the SmartCube behavioral assay and showed anxiolytic-like signatures following daily dose administ
240 s a clinically available, non-benzodiazepine anxiolytic medication that acts on both serotonin and do
241 s a clinically available, non-benzodiazepine anxiolytic medication that acts on serotonin and dopamin
242 nts had increased risk of antidepressant and anxiolytic medication use, while patients with mild AD o
245 erated because of patient anxiety, yet acute anxiolytic medications typically cause sedation and impa
246 ety to the point that intravenous anesthetic/anxiolytic medications were discontinued and cognitive t
248 europeptide Y (NPY) is a putative endogenous anxiolytic neurotransmitter that adaptively regulates re
252 neous colitis and, in stressed mice, induced anxiolytic or fear-reducing effects as measured on the e
255 epines (BZDs) represent the gold standard of anxiolytic pharmacotherapy; however, their clinical bene
256 orebrain in fb-A2AR KO mice also produced an anxiolytic phenotype in both the elevated plus maze and
258 c hormone, but surprisingly, have a profound anxiolytic phenotype when evaluated using multiple stres
259 Rit2 knockdown (Rit2-KD), mice displayed an anxiolytic phenotype, with no change in baseline locomot
261 GABAergic projections produced rewarding and anxiolytic phenotypes, which were also recapitulated by
263 er health care visits and antidepressant and anxiolytic prescriptions in 2015 as a function of gender
264 order health care visits, antidepressant and anxiolytic prescriptions, and hospitalization after a su
267 nociceptin may underlie its anti-alcohol and anxiolytic properties and identify the nociceptin recept
269 activates eEF2 also in neurons to exert its anxiolytic properties in the PVN, we performed in vivo a
270 E STATEMENT: Neuropeptide Y (NPY) has robust anxiolytic properties, and its levels are reduced in pat
273 dered beneficial to mental health due to its anxiolytic, prosocial and antistress effects, but eviden
276 ynaptic GABAARs could mediate the maintained anxiolytic response to EtOH in dependent individuals, ra
280 s in modulating anxiety, establish separable anxiolytic roles for different anterodorsal BNST project
283 s a more sensitive measure of the effects of anxiolytics than traditional spatiotemporal indices.
284 AH inhibitors may represent a novel class of anxiolytics that specifically target stress-induced anxi
288 d PTSD and women receiving antidepressant or anxiolytic treatment would be more likely to experience
292 fear vigilance is similar to that seen with anxiolytic treatments in the same cognitive paradigm.
295 ment were treatment naivety, anxiety, use of anxiolytics, use of antidepressants, use of opioids, rib
296 wn to have procognitive, antipsychotic-like, anxiolytic, weight-reducing, glucose-lowering, and wake-
299 ation of benzodiazepines, Z-drugs, and other anxiolytics with incident dementia in patients with affe