ライフサイエンスコーパス: aortic atherosclerosis

1 by TEMRI in 22 subjects (8 normals, 14 with aortic atherosclerosis).

2 esity, changes in plasma lipids, and reduced aortic atherosclerosis.

3 ensitivity, but also ameliorated significant aortic atherosclerosis.

4 nt (Ldlr-/-) C57BL/6 male mice had increased aortic atherosclerosis.

5 e in the elderly and in patients with severe aortic atherosclerosis.

6 ce developed significantly more diet-induced aortic atherosclerosis.

7 rol levels on a chow diet and develop severe aortic atherosclerosis.

8 <.001 for IgM) correlated with the extent of aortic atherosclerosis.

9 od pressure is independently associated with aortic atherosclerosis.

10 od may prove useful for the in vivo study of aortic atherosclerosis.

11 d for quantitative analysis of the extent of aortic atherosclerosis.

12 complementary information regarding thoracic aortic atherosclerosis.

13 s recently been associated with coronary and aortic atherosclerosis.

14 s noted in apoE(-/-) and LDLR(-/-) mice with aortic atherosclerosis.

15 paralleled the susceptibility to developing aortic atherosclerosis.

16 ty, glucose tolerance, hepatic steatosis and aortic atherosclerosis.

17 /PC-treated mice demonstrated no increase in aortic atherosclerosis (11 +/- 1% versus 10 +/- 4%, P=NS

18 e at 25 weeks demonstrated a 32% increase in aortic atherosclerosis (11 +/- 1% versus 15 +/- 4%, P=.0

19 FvQ/Q,ApoE-/- mice (n=8) had developed more aortic atherosclerosis (40+/-6% lesion area) compared wi

20 Predictors of type I outcomes were proximal aortic atherosclerosis, a history of neurologic disease,

21 sis and risk of being in the top quartile of aortic atherosclerosis after adjustment for the Framingh

22 deposits is an indicator of the presence of aortic atherosclerosis and an independent predictor of c

23 iation between atherosclerosis risk factors, aortic atherosclerosis and aortic valve abnormalities in

24 Early-life risk factor exposure increases aortic atherosclerosis and blood pressure in humans and

25 s used to assess independent associations of aortic atherosclerosis and cardiovascular events.

26 An atherogenic diet induced aortic atherosclerosis and exacerbated cerebral beta-amy

27 LCHP-fed mice developed more aortic atherosclerosis and had an impaired ability to ge

28 nant A-I(Milano)/PC prevented progression of aortic atherosclerosis and reduced lipid and macrophage

29 MaxV50 was strongly predictive of extent of aortic atherosclerosis and risk of being in the top quar

30 ivariate analysis, prior neurological event, aortic atherosclerosis, and duration of cardiopulmonary

31 oke were prior neurological event, diabetes, aortic atherosclerosis, and the combined end points of l

32 tly underestimated the severity of ascending aortic atherosclerosis, and this underestimation was mor

33 Atherosclerosis risk factors and proximal aortic atherosclerosis are independently associated with

34 MR imaging measures of aortic atherosclerosis are predictive of future adverse

35 A direct comparison of the severity of aortic atherosclerosis between female LDLr(-/-) and LDLr

36 heart failure, left ventricular hypertrophy, aortic atherosclerosis, bicaval venous cannulation, with

37 of beta-arrestin2 in ldlr(-/-) mice reduced aortic atherosclerosis by 40% and decreased the prevalen

38 , apoA-IMilano gene therapy (n = 15) reduced aortic atherosclerosis by 65% (p < 0.001) and plaque mac

39 up to 50%, whereas HL-S145G markedly reduced aortic atherosclerosis by up to 96% (p < 0.02) in both m

40 Finally, aortic atherosclerosis development was significantly low

41 s on the extent and severity of coronary and aortic atherosclerosis, even in the presence of a favora

42 tension, a major risk factor for stroke, and aortic atherosclerosis has not been determined in the ge

43 ations between atherosclerosis risk factors, aortic atherosclerosis (imaged by transesophageal echoca

44 thesis that apo A-I(Milano)/PC would inhibit aortic atherosclerosis in apo E-deficient mice.

45 CRP transgene expression causes accelerated aortic atherosclerosis in apoE-/- mice.

46 non-HDL-C, or on the development of proximal aortic atherosclerosis in C57Bl/6, apoE-KO, or LDLr-KO m

47 pid profile led to significantly lower (65%) aortic atherosclerosis in hABCA1-Tg mice.

48 associated with the presence or severity of aortic atherosclerosis in the general population.

49 E-/- mice developed considerably accelerated aortic atherosclerosis in the presence of a similar seru

50 OUTCOME MEASURES: Prevalence of coronary and aortic atherosclerosis in the US armed forces and by age

51 es the severity of asymptomatic coronary and aortic atherosclerosis in young people.

52 In control mice, from 20 to 25 weeks, aortic atherosclerosis increased by 59% (11 +/- 1% versu

53 The extent of aortic atherosclerosis increased from 2 to 3 mo and from

54 Quantitative morphometric analysis of the aortic atherosclerosis indicated that the transgenic ani

55 inical and pathologic evidence that thoracic aortic atherosclerosis is an important embolic source, d

56 his study was to investigate whether complex aortic atherosclerosis is associated with increased risk

57 In selected high-risk patients, aortic atherosclerosis is associated with increased risk

58 Aortic atherosclerosis may not be an independent risk fa

59 Measures of aortic atherosclerosis may provide heritable quantitativ

60 g history were independently associated with aortic atherosclerosis of any degree (P:</=0.001) and wi

61 d pressure variables associated with complex aortic atherosclerosis (protruding plaques >/=4 mm thick

62 presence of intracranial but not coronary or aortic atherosclerosis significantly increased the odds

63 serum lipoprotein levels and the presence of aortic atherosclerosis suggested that intrinsic alterati

64 an the unstable group and significantly less aortic atherosclerosis than each of the other 2 groups.

65 so lacked TLR4 or MyD88 demonstrated reduced aortic atherosclerosis that was associated with reductio

66 ible to identify perioperatively significant aortic atherosclerosis (using transesophageal echocardio

67 igh-fat feeding, pneumonitis was absent, but aortic atherosclerosis was 2- to 6-fold greater in beta3

68 Aortic atherosclerosis was almost completely prevented i

69 Aortic atherosclerosis was analyzed in low-density lipop

70 After 22 weeks of treatment, rank order of aortic atherosclerosis was control>vitamin E (with or wi

71 transplantation, at which time the extent of aortic atherosclerosis was determined.

72 ciation between blood pressure variables and aortic atherosclerosis was evaluated by multiple logisti

73 The association between genotype and aortic atherosclerosis was examined in 145 human aortas.

74 Aortic atherosclerosis was identified with Sudan IV stai

75 om the pro-atherogenic plasma lipid profile, aortic atherosclerosis was increased 10-fold in ABCA1-Tg

76 Advanced aortic atherosclerosis was induced in 18 rabbits by athe

77 The extent of aortic atherosclerosis was measured by planimetry of the

78 Aortic atherosclerosis was measured by quantifying mean

79 Aortic atherosclerosis was present in all mice on the hi

80 Despite decreased HDL, aortic atherosclerosis was significantly reduced (-35% t

81 edicting the top quartile of gender-specific aortic atherosclerosis were 0.57, 0.60, and 0.75 for mod

82 , however, SCD1 inhibition strongly promoted aortic atherosclerosis, which could not be reversed by d

83 -/-) mice were fed a western diet to develop aortic atherosclerosis with aortas then transplanted int