ライフサイエンスコーパス: aortic dissection

1 delayed aortic repair ("complicated chronic aortic dissections").

2 regnancy (such as acute coronary syndrome or aortic dissection).

3 topathy, and complications (endocarditis and aortic dissection).

4 tic dissection, 5% have a history of a prior aortic dissection.

5 ology, risk factors, and molecular nature of aortic dissection.

6 fy true and false lumina on CT angiograms of aortic dissection.

7 patients undergoing surgery for acute type A aortic dissection.

8 4.7-21.9) and 3.4 (CI: 1.3-8.8) for chronic aortic dissection.

9 structural components of the aortic wall to aortic dissection.

10 ut none in patients with a family history of aortic dissection.

11 bility of the aortic wall to Ang II-mediated aortic dissection.

12 ment for dilated ascending aortas to prevent aortic dissection.

13 n patients with Marfan syndrome who suffered aortic dissection.

14 represents a therapeutic concept for type B aortic dissection.

15 a new potential biomarker for TAA and acute aortic dissection.

16 significant treatable risk factor for acute aortic dissection.

17 valve (BAV) disease, with increased risk of aortic dissection.

18 aortic dissection, and 114 with acute type B aortic dissection.

19 , 39 years) had a first-degree relative with aortic dissection.

20 onsidered for an aortic operation to prevent aortic dissection.

21 cular the aorta, to prevent life-threatening aortic dissection.

22 ive clinical tool for the detection of acute aortic dissection.

23 es to assist in the early detection of acute aortic dissection.

24 aspinal muscles occurring after acute type A aortic dissection.

25 dex > or = 2.5 cm/m2 are at highest risk for aortic dissection.

26 he hospital among patients with type B acute aortic dissection.

27 comes of medical management for acute type B aortic dissection.

28 proximal aorta dilatation, which can lead to aortic dissection.

29 ic diameter thresholds without occurrence of aortic dissection.

30 rited arrhythmia syndrome, and aortopathy or aortic dissection.

31 ic remodelling after TEVAR in chronic Type B aortic dissection.

32 ents after an initially uncomplicated type-B aortic dissection.

33 athological mechanical mechanisms underlying aortic dissection.

34 tribute to risk for presenting with an acute aortic dissection.

35 cending thoracic aorta, leading to ascending aortic dissections.

36 ay be protective in the prevention of type B aortic dissections.

37 ocus 16p13.1 predispose individuals to acute aortic dissections.

38 tients who underwent acute or chronic type B aortic dissections.

39 r (TEVAR) is used in the treatment of type B aortic dissections.

40 nction mutations in MYLK are associated with aortic dissections.

41 disorders, including aneurysmal disease and aortic dissections.

42 , and development of thoracic and suprarenal aortic dissections.

43 Endocarditis (4.5% versus 2.5%, P=0.037) and aortic dissections (0.5% versus 0%, P<0.001) occurred mo

44 ortic aneurysms (TAA), 2701 (24%) descending aortic dissections, 1033 (9%) thoracic aortic ruptures,

45 Of those with spontaneous aortic dissections, 18 of 19 (95%) had an associated car

46 romes in the International Registry of Acute Aortic Dissection (1996-2011) were evaluated to examine

47 Of 2538 patients with acute aortic dissection, 2430 (95.7%) were identified by 1 or

48 opathy (3, 8%), myocarditis related (3, 8%), aortic dissection (3, 8%), and idiopathic left ventricul

49 had type A aortic dissection, 53 had type B aortic dissection, 35 had intramural aortic hematoma, 18

50 Among those suffering acute aortic dissection, 5% have a history of a prior aortic d

51 In chronic (after 6 weeks) type B aortic dissection, 5-year survival of 60% to 80% was exp

52 events, 54 patients had 59 thoracoabdominal aortic dissections (52 incident events: 6/100 000, 95% c

53 y-one patients (13%) had AAS: 125 had type A aortic dissection, 53 had type B aortic dissection, 35 h

54 of affected individuals presented with acute aortic dissections (63%) at relatively young ages (mean

55 The main cause of death was aortic dissection (9 of 15; 60%), which occurred at mild

56 rgery to transfer patients with acute type A aortic dissection-a catastrophic disease that requires p

57 is urgently needed for acute Stanford type A aortic dissection (AAAD) patients due to its high mortal

58 Primary presentation was acute aortic dissection (AAD) in 36% (77% type A, 23% type B)

59 ding aorta that occasionally leads to type A aortic dissection (AAD).

60 The outcome of patients with acute type B aortic dissection (ABAD) is strongly related to their cl

61 demonstrated that an indication of TEVAR for aortic dissection (acute P = 0.000212; chronic P = 0.006

62 Improved medical care after initial aortic dissection (AD) has led to increased survivorship

63 The epidemiology of aortic dissection (AD) has not been well described among

64 Aortic dissection (AD) is a life-threatening emergency.

65 Aortic dissection (AD) is the most common acute conditio

66 lity from thoracic aortic aneurysm (TAA) and aortic dissection (AD) with the aim of identifying assoc

67 ndovascular aortic repair (TEVAR) for type B aortic dissection (AD).

68 rexpression and tested the susceptibility to aortic dissection after angiotensin II (Ang II) infusion

69 Iatrogenic aortic dissection after interventional procedures is inf

70 ract obstruction, unexplained hypoxemia, and aortic dissection, among others, can all be reliably per

71 (80% survival at 60 years), aortic risk (23% aortic dissection and 18% preventive aortic surgery), an

72 Patients with aortic dissection and active endocarditis were excluded.

73 rs of mortality, including family history of aortic dissection and age, can be included in an Aortopa

74 s (FQs) to cardiac adverse events, including aortic dissection and aneurysm.

75 Indomethacin prevented death from abdominal aortic dissection and decreased incidence of aortic diss

76 partum complications, the prevalence of both aortic dissection and elective aortic surgery during lon

77 Aortic dissection and intramural haematoma comprise an a

78 eurysm taking CCBs display increased risk of aortic dissection and need for aortic surgery, compared

79 Case series have described aortic dissection and rupture in pregnancy.

80 subsequent life-threatening complications of aortic dissection and rupture.

81 d women with Turner syndrome are at risk for aortic dissection and rupture.

82 en, 52.4 years; range, 35.0-77.0 years) with aortic dissection and spinal (n = 4), renal (n = 7), mes

83 y clinical parameters associated with type B aortic dissection and to develop a risk model to predict

84 cy setting, 365 patients suspected of having aortic dissection and/or other aortic disorders underwen

85 4/80- macrophage accumulation selectively in aortic dissections and not in aortas from Il6-/- mice.

86 Aortic events (aortic surgery or aortic dissection) and deaths were evaluated during the

87 cic aortic aneurysm, 195 with chronic type B aortic dissection, and 114 with acute type B aortic diss

88 ic aortic root surgery, 5 experienced type A aortic dissection, and 12 died (noncardiovascular causes

89 is (including need for aortic valve surgery, aortic dissection, and all-cause mortality).

90 mplications, including aortic valve surgery, aortic dissection, and all-cause mortality.

91 iac output that required mechanical support, aortic dissection, and annular rupture; technical compli

92 s for thoracic aortic aneurysm, acute type B aortic dissection, and chronic type B aortic dissection,

93 s for thoracic aortic aneurysm, acute type B aortic dissection, and chronic type B aortic dissection,

94 l hematoma (IMH) is an important subgroup of aortic dissection, and controversy surrounds appropriate

95 licated in the pathology of aortic aneurysm, aortic dissection, and more recently, vascular dementia.

96 te for coronary disease, pulmonary embolism, aortic dissection, and other thoracic disease.

97 nonrobust evidence for management of type B aortic dissection, and that literature results were larg

98 a virus infection affects susceptibility for aortic dissection, and whether this risk can be attenuat

99 ctin, cause thoracic aortic aneurysms, acute aortic dissections, and occlusive vascular diseases.

100 revious aneurysm surgery, splenectomy, acute aortic dissection, aneurysm type, older age, and history

101 Aortic dissection (AoD) is a serious complication of tho

102 change in aortic regurgitation; the time to aortic dissection, aortic-root surgery, or death; somati

103 gencies (ruptured abdominal aortic aneurysm, aortic dissection, appendicitis, perforated esophagus, p

104 .22) for ruptured abdominal aortic aneurysm, aortic dissection, appendicitis, perforated esophagus, p

105 AAS, including aortic dissection (approximately 90% of cases) and intra

106 Acute aortic dissections are a preventable cause of sudden dea

107 Triggering events for acute aortic dissections are incompletely understood.

108 Acute type A aortic dissections are often treated with prosthetic rep

109 Ruptured aortic aneurysm and aortic dissections are potentially preventable disorders

110 Thoracic aortic dissection, ascending aortic aneurysm, and aortic

111 Aortic dissections associate with medial degeneration, t

112 gnostic tools and management of acute type A aortic dissection (ATAAD) have undergone substantial evo

113 y was to compare the results of acute type A aortic dissection (ATAAD) repair before and after implem

114 sociation between admission for acute type A aortic dissection (ATAAD) to the University of Michigan

115 vascular era, the management of acute type B aortic dissection (ATBAD) is undergoing dramatic changes

116 y had not undergone aortic surgery or had an aortic dissection before their first visit.

117 had chronic type A, and 3 had chronic type B aortic dissections before surgery.

118 olled in the International Registry of Acute Aortic Dissection between 1996 and 2003 and who survived

119 olled in the International Registry of Acute Aortic Dissection between 1996 and 2005 (mean age, 60.8

120 beneficiaries diagnosed with an acute type A aortic dissection between 1999 and 2014 who (1) were tra

121 who have thoracic aortic aneurysms or acute aortic dissections but who do not have syndromic feature

122 fects outcomes in patients with acute type A aortic dissection, but reliable quantitative data are la

123 aortic dissection and decreased incidence of aortic dissection by as high as 40%.

124 logic aortic growth and decrease the risk of aortic dissection by decreasing hemodynamic stress.

125 gically repaired immediately, whereas type B aortic dissection can be treated medically.

126 educe the risk of aortic dissection However, aortic dissection can occur in Turner syndrome without c

127 rd University since the establishment of the aortic dissection classification 50 years ago.

128 Aortic dissection, commonly type B, occurs in an appreci

129 who died of COVID-19 after open repair of an aortic dissection, complicated by hypoxic respiratory fa

130 ed the IRAD (International Registry of Acute Aortic Dissection) database to examine the clinical prof

131 The 3-year rates of aortic-root surgery, aortic dissection, death, and a composite of these event

132 In acute aortic dissection, delays exist between presentation and

133 An aortic dissection detection (ADD) risk score of 0 to 3 w

134 l for pretest probability assessment was the aortic dissection detection risk score (ADD-RS, 0-3) per

135 Delays in acute aortic dissection diagnosis occurred in female patients;

136 ssection or the combined end point of type B aortic dissection, distal aortic surgery, and death.

137 Nine patients developed new distal aortic dissections during follow-up.

138 patients discharged alive with acute type B aortic dissection enrolled in the International Registry

139 c surgery are at substantial risk for type B aortic dissection, even when the descending aorta is onl

140 ort from the International Registry of Acute Aortic Dissection examines this hypothesis.

141 The probability of aortic dissection extension to the supra-aortic vessels

142 ntry by means of balloon fenestration of the aortic dissection flap.

143 ld be considered in patients with a thoracic aortic dissection, followed by cascade screening of fami

144 nts with acute uncomplicated Stanford type-B aortic dissection, followed over a median of 850 (interq

145 olled in the International Registry of Acute Aortic Dissection from 1996 to 2009.

146 l thoracic aortic aneurysms leading to acute aortic dissections (FTAAD).

147 genetic testing of known hereditary thoracic aortic dissection genes should be considered in patients

148 olled in the International Registry of Acute Aortic Dissection had cardiac surgery before dissection,

149 Patent false lumen in aortic dissection has been associated with poor prognosi

150 hrombosis of the false lumen in type B acute aortic dissection has been found to predict outcomes.

151 ker therapy was associated with fewer type B aortic dissections (hazard ratio: 0.3; 95% confidence in

152 tions appears to markedly reduce the risk of aortic dissection However, aortic dissection can occur i

153 acin administration reduces rate of onset of aortic dissection in a murine model of the condition.

154 risk model, the 10-year occurrence of type B aortic dissection in low-, moderate-, and high-risk pati

155 collaborating societies address the risk of aortic dissection in patients with bicuspid aortic valve

156 Data on outcomes after Stanford type A aortic dissection in patients with Marfan syndrome are l

157 nd to develop a risk model to predict type B aortic dissection in patients with Marfan syndrome.

158 The risk for type B aortic dissection in the same population was 0.5 events/

159 izing the surgical treatment of acute type A aortic dissection in the United States.

160 ion is close to the remaining risk of type A aortic dissection in this population, which underlines t

161 own whether aortic dilatation precedes acute aortic dissection in TS and, if so, what specific diamet

162 Cardiovascular anomalies and risk for aortic dissection in Turner syndrome are strongly linked

163 Aortic dissection in Turner syndrome occurs in young ind

164 rome is the most common established cause of aortic dissection in young women, but has received littl

165 termined incidence and outcomes of all acute aortic dissections in a population of 92 728 in Oxfordsh

166 thoracic aorta occurs after TEVAR for type B aortic dissections in patients with thoracic FLT and FLP

167 T) and p.S1759P (c.5275T>C), segregated with aortic dissections in two families with a maximum LOD sc

168 Comprehensive search for aortic dissections in undiagnosed bicuspid valves reveal

169 additional patients, allowing estimation of aortic dissection incidence in bicuspid valve patients i

170 Aortic dissection incidences for patients 50 years or ol

171 tention has turned to the 'variant forms' of aortic dissection: intramural hematoma and penetrating a

172 Aortic dissections involving the descending aorta are a

173 olled in the International Registry of Acute Aortic Dissection (IRAD) between 1996 and 2003.

174 olled in the International Registry of Acute Aortic Dissection (IRAD) between 1996 and 2003.

175 olled in the International Registry of Acute Aortic Dissection (IRAD) between 1996 and January 2007 w

176 ty using the International Registry of Acute Aortic Dissection (IRAD).

177 Acute type A aortic dissection is a lethal condition requiring emerge

178 Aortic dissection is a life-threatening condition, which

179 Acute aortic dissection is a preventable life-threatening cond

180 Thoracic aortic dissection is an emergent life-threatening condit

181 Medical management for acute type B aortic dissection is associated acceptable outcomes.

182 nitially uncomplicated acute Stanford type-B aortic dissection is associated with a high rate of late

183 The risk of type B aortic dissection is close to the remaining risk of type

184 The risk for aortic dissection is greatly increased in young women wi

185 The risk for aortic dissection is increased among relatively young wo

186 Risk for acute aortic dissection is increased by more than 100-fold in

187 High IFM in chronic Type B aortic dissection is linked to improved aortic remodelli

188 plicated acute, subacute, and chronic type B aortic dissection is managed with close image monitoring

189 eening for genetic variants causing thoracic aortic dissection is not currently performed for patient

190 The incidence of aortic dissection is significantly increased in individu

191 Aortic dissection is the most devastating complication o

192 A new appraisal of the management of acute aortic dissection is timely because of recent developmen

193 eometry of the thoracic aorta is affected by aortic dissection, leading to an increase in diameter th

194 IVUS assessment of IFM in chronic Type B aortic dissection might be helpful in identifying patien

195 complicated" and uncomplicated" acute type A aortic dissection, might help predict individual risk as

196 ome sequencing of 240 patients with thoracic aortic dissection (n=235) or rupture (n=5) and 258 contr

197 eg, endovascular stenting, for acute type B aortic dissection need to be compared with these results

198 m cardiogenic shock on day 50 after a type A aortic dissection, not related to treatment.

199 Aortic dissection occurred in 2 of 416 patients; inciden

200 No aortic dissection occurred.

201 During approximately 3 years of follow-up, aortic dissections occurred in 3 women with TS, for an a

202 Between 1998 and 2013, 54 type B aortic dissections occurred in 600 patients with Marfan

203 Three type A aortic dissections occurred in this population during th

204 graphy <2 years before and within 12 h after aortic dissection onset.

205 ascending aortic diameter was <55 mm before aortic dissection onset.

206 ndograft during follow-up after acute type A aortic dissection open repair.

207 pothetical diagnoses have emerged: either an aortic dissection or an atrial myxoma.

208 Finally, imaging of a patient with aortic dissection or aneurysm will be discussed, as its

209 No woman experienced aortic dissection or required cardiac surgery during pre

210 iated with a significantly increased risk of aortic dissection or rupture (incidence rate ratio, 4.0;

211 rent strategies to assess the future risk of aortic dissection or rupture are based primarily on moni

212 n 4 933 697 women, we identified 36 cases of aortic dissection or rupture during the pregnancy or pos

213 The risk of aortic dissection or rupture is elevated during pregnanc

214 hich is generally silent but can precipitate aortic dissection or rupture with devastating and often

215 ition in that it places patients at risk for aortic dissection or rupture.

216 Our outcome was a composite of aortic dissection or rupture.

217 inical condition that can cause death due to aortic dissection or rupture.

218 follow-up period of 2.7 years, there were no aortic dissections or deaths, but 16 of 83 (19%) patient

219 Aortic dissections originating in the ascending aorta an

220 ation of patients with BAV, the incidence of aortic dissection over a mean of 16 years of follow-up w

221 However, few studies of acute aortic dissection patients and aortic size exist.

222 presentations and prompt transport of acute aortic dissection patients could reduce crucial time var

223 Acute aortic dissection patients enrolled in the International

224 We used data from our registry of acute aortic dissection patients to better understand the rela

225 ersus 11 to 13 (aortic aneurysm) and 2 to 3 (aortic dissections) per 100 000 person-years among contr

226 risk for possible aortic dissection (proven aortic dissection plus death of unknown cause, 0.7 event

227 al: 61% [n=101]; P=0.5), 25 for acute type A aortic dissection (porcine: 32% [n=8]; mechanical: 68% [

228 ed using the International Registry of Acute Aortic Dissection pre-operative prediction model.

229 majority of patients with acute type A acute aortic dissection present with aortic diameters <5.5 cm

230 A total of 140 patients with stable type B aortic dissection previously randomized to optimal medic

231 s/1,000 patient-years) and risk for possible aortic dissection (proven aortic dissection plus death o

232 reports have identified retrograde ascending aortic dissection (rAAD) as a potentially lethal complic

233 cipated in the International Turner Syndrome Aortic Dissection Registry.

234 ng complications, such as annulus rupture or aortic dissection, remained stable over time, whereas ra

235 ently, the optimal treatment of acute type B aortic dissection remains controversial.

236 ndovascular aortic repair (TEVAR) in chronic aortic dissection remains controversial.

237 Risk of sudden death or aortic dissection remains low in patients with Marfan sy

238 Aortic dissection remains the most common aortic catastr

239 ntify patients with complicated acute type B aortic dissection requiring urgent aortic repair.

240 type B aortic dissection, and chronic type B aortic dissection, respectively.

241 type B aortic dissection, and chronic type B aortic dissection, respectively.

242 isciplinary panel in the treatment of type B aortic dissection reviewed available literature to devel

243 nd Marfan syndrome have been associated with aortic dissection risk, but it is unknown whether the pr

244 ilatation of the aortic wall and can lead to aortic dissection, rupture, and other life-threatening c

245 The classification proposed that type A aortic dissection should be surgically repaired immediat

246 f subacute (2 to 6 weeks after onset) type B aortic dissection showed an early mortality rate of 2.8%

247 fically with non-familial, sporadic thoracic aortic dissection (STAD) and compared them to the genoty

248 four instances of pulmonary embolism, three aortic dissections (Stanford type A), three myocardial i

249 -compliant retrospective study to assess all aortic dissection studies performed at the University of

250 of lysyl oxidases in turkeys and rats causes aortic dissections, support the conclusion that rare gen

251 and management of patients with type A acute aortic dissection (TAAAD).

252 Thoracic aortic aneurysms and acute aortic dissections (TAADs) occur as a result of genetica

253 Thoracic aortic dissection (TAD) is an aggressive vascular diseas

254 Stanford Type B acute aortic dissection (TB-AAD) spares the ascending aorta an

255 dard for treating acute uncomplicated type B aortic dissection (TBAD) has been aggressive medical the

256 a on thoracic aortic aneurysms (TAA), type B aortic dissections (TBAD), and traumatic aortic injuries

257 Prevalence of previous aortic dissection tended to be higher in males than fema

258 t diameter prior to or at the time of type A aortic dissection tended to be smaller in patients carry

259 In this study of survivors of type B aortic dissection, TEVAR in addition to optimal medical

260 For acute (first 2 weeks) type B aortic dissection, the pooled early mortality rate was 6

261 s in abdominal aortic aneurysms and thoracic aortic dissections to thrombosis in stenotic arteries fo

262 centers on 2 continents reviewed their acute aortic dissection type A databases, which contained 1,82

263 Aortic dissection type A is a disease with high mortalit

264 to the multicenter German Registry for Acute Aortic Dissection Type A were analyzed.

265 rolled in GERAADA (German Registry for Acute Aortic Dissection Type A) who underwent surgery between

266 Among 1324 consecutive patients with aortic dissection type A, 74 with Marfan syndrome (58% m

267 rols (1:10 for aortic aneurysm and 1:100 for aortic dissection) using the Danish nationwide administr

268 ve care unit, myocardial infarction, stroke, aortic dissection, valve thrombosis, endocarditis, and u

269 The incidence of aortic dissection was 0.06%.

270 The odds ratio of RTAD for an acute aortic dissection was 10.0 (CI: 4.7-21.9) and 3.4 (CI: 1

271 The Stanford classification of aortic dissection was described in 1970.

272 In the more than 250 years since thoracic aortic dissection was first described, much has been lea

273 No infective endocarditis or aortic dissection was found.

274 daily oral administration) to mice in which aortic dissection was induced using beta-aminopropionitr

275 Presentation with aortic dissection was more common for NS-TAA than MFS or

276 Aortic dissection was observed in 1.6% of pregnancies.

277 No aortic dissection was observed in Marfan syndrome patien

278 The long-term incidence of thoracic aortic dissection was significantly higher in patients w

279 Aortic dissection was suspected clinically, so the patie

280 Event rate (death/aortic dissection) was 0.17%/y.

281 2007, through December 31, 2013, for type B aortic dissection were analyzed.

282 Risk factors for death and aortic dissection were identified by Cox proportional ha

283 Independent variables associated with type B aortic dissection were prior prophylactic aortic surgery

284 New cases of endocarditis and aortic dissection were recorded.

285 Rates of aortic dissection were similar between women and men.

286 with the confirmed diagnosis of acute type B aortic dissection were studied.

287 2014, 40.5% of patients with an acute type A aortic dissection were transferred, and 51.9% received s

288 and May 2008, 251 patients with acute type A aortic dissection were treated, including 36 (14.3%) wit

289 Residual and new aortic dissections were the leading cause of death.

290 s (CNS hemorrhage, sudden cardiac death, and aortic dissection) were observed.

291 mice was sufficient to cause Ang II-mediated aortic dissection, which was never observed in wild-type

292 The number of patients with confirmed acute aortic dissection who presented with 1 or more of 12 pro

293 of a patient presenting with an acute type A aortic dissection who presented with bilateral lower ext

294 We examined 201 patients with type B acute aortic dissection who were enrolled in the International

295 tially reduced in patients with acute type A aortic dissection who were rerouted to high-volume hospi

296 re at high-volume hospitals for acute type A aortic dissections will lower mortality.

297 characterized by presentation with an acute aortic dissection with little to no enlargement of the a

298 eated type B, were discharged after an acute aortic dissection with patent false lumen.

299 Aortic dissection with persistent patent false lumen car

300 yocardial infarction, pulmonary embolus, and aortic dissection, with an eye to improving emergency de