ライフサイエンスコーパス: apical cell

1 detectable within the two descendants of the apical cell.

2 l, a stalk cell, and a cytoplasmically dense apical cell.

3 a single stem cell known as the gametophore apical cell.

4 pment and each module develops from a single apical cell.

5 ctly positions the division plane in the bud apical cell.

6 (-/-) mice, but to a much lesser extent than apical cells.

7 e occurred at P9-P12 in basal and P12-P15 in apical cells.

8 bbles to deliver drugs into the cytoplasm of apical cells.

9 iction imposed on the daughters of the first apical cells.

10 milar between yeast and serum-induced hyphal apical cells.

11 in via repression of the neural ring fate in apical cells.

12 atens gametophyte, including the gametophore apical cells.

13 rity, a pattern that breaks at branching and apical cells.

14 e activity and expression with the number of apical cells.

15 such is crucial for the bursting pattern in apical cells.

16 spicuous inverted, pyramidal cell called the apical cell (AC), which is unidentified in angiosperms.

17 on was sufficient to drive subtle changes in apical cell adhesion and subcellular Yap translocation,

18 We propose that apextrin is involved in apical cell adhesion and that its high level of expressi

19 rophinin is a membrane protein that mediates apical cell adhesion between trophoblastic cells and lum

20 Our data defines apical cell-adhesion as the earliest known substrate for

21 gral structural and functional components of apical cell adhesions (tight junctions).

22 The ATML1 gene was first expressed in the apical cell after the first asymmetric division of the z

23 ter recovery of I(Ca) from inactivation than apical cells allowing them to support a higher AP freque

24 ote divides asymmetrically into an embryonic apical cell and a basal cell with mostly extra-embryonic

25 ing cell fate progression in the gametophore apical cell and found upregulation of cytokinin biosynth

26 suggested by Vernon and Meinke, in which the apical cell and its decendents normally suppress the emb

27 reas of the filament, namely the dome of the apical cell and the shanks of the central round cells.

28 We show that Boi is expressed in apical cells and exerts its suppressive effect on FSC pr

29 RABA4d are normally localized at the tip of apical cells and their localization is correlated with r

30 no PpCLE expression specifically marked the apical cells, and PpCLV1b and PpRPK2 expression initiall

31 gametophore apices, PpCLE3 expression marked apical cells, and PpCLV1b and PpRPK2 overlapped.

32 e were able to demonstrate directly that the apical cells are derived from a stratification of the em

33 cells generates polarity such that the outer apical cells are trophectoderm (TE) precursors and the i

34 but the mechanisms of their release from the apical cells are unknown.

35 helial cells rises with increasing projected apical cell area in a nonlinear fashion.

36 nodes linked by filaments that contract the apical cell area.

37 visions of the zygote, the decendents of the apical cell arrest.

38 Because citrate is released from root apical cells as the deprotonated anion, we used the patc

39 ive vesicle trafficking in the shanks of the apical cell, as inferred from the model.

40 redicted the site of branch formation in the apical cell at the onset of mitosis, which occurs one to

41 rentially regulated during development, with apical cells being more strongly dependent on experience

42 ry sky" pattern in which there was a lack of apical cell binding (hence, dark sky) but increased bind

43 [Ca(2+)](cyto) were seen in the dendrite and apical cell body, while relaxations of the carbachol-ind

44 erved that PMCA2 is rapidly delivered to the apical cell border from where it diffuses to the entire

45 reocilia membrane and is internalized at the apical cell border maintaining an estimated half-life of

46 )hHsp27 associated with basolateral, but not apical, cell borders in injured cells.

47 is integral to the tight junction (TJ), the apical cell-cell adhesion and a key regulator of the epi

48 f either N-cadherin or N-CAM otic cells lose apical cell-cell contact and their epithelial shape.

49 Apical cell-cell contact zones and actomyosin only later

50 cortical tension, but by dynamic linking of apical cell-cell contact zones to an already contractile

51 Sdt heterodimer is not only recruited to the apical cell-cell contacts by binding to Crb but depends

52 inherited apicobasal polarity, together with apical cell-cell interactions drive the morphological an

53 myosin IIB localized at the basal cortex and apical cell-cell junctions and promoted CD59 uptake from

54 DAPLE localizes to apical cell-cell junctions in the neuroepithelium, where

55 The length of the most apical cell-cell junctions was reduced, and basolateral

56 Tight junctions (TJs) are the most apical cell-cell junctions, and claudins, the recently i

57 t of apical-basal polarity, the formation of apical cell-cell junctions, and polarized secretion.

58 Apical cell-cell junctions, including adherens junctions

59 reatment was effective in both the basal and apical cell compartment, resulting in a notable reductio

60 crease in Ci(155) levels, nuclear migration, apical cell constriction and an acceleration of the furr

61 a G protein signaling pathway that promotes apical cell constriction during neurulation.

62 Rs instruct G proteins to promote collective apical cell constriction in the context of epithelial ti

63 nous and ROCK and that it elicited a wave of apical cell constriction that culminated in the formatio

64 ctions of neuroepithelial cells and promotes apical cell constriction via G-protein activation.

65 dependent morphogenetic events that includes apical cell constriction, localized alignment of groups

66 ct to promote stable myosin accumulation and apical cell constriction, loss-of-function phenotypes fo

67 a conserved mechanism for this kinase during apical cell constriction.

68 During gastrulation, Fog induces apical cell constrictions that drive the invagination of

69 d that repeated contraction and expansion of apical cell contacts affect these dynamics.

70 alance, repeatedly contracting and expanding apical cell contacts to organize the epithelium of the d

71 We found that shoot apical cells contain high levels of IAA and that IAA dec

72 In response to rings and patches of apical cell contractility, model epithelia smoothly defo

73 ateral cell cortex, and is excluded from the apical cell cortex of dividing cells.

74 ynamics and elevated cortical tension in the apical cell cortex of endoderm precursor cells.

75 nd preferentially recruit myosin-II to their apical cell cortex rather than to apical cap localisatio

76 Activation of the apical cell death caspase Dronc is necessary and suffici

77 dBruce does not block the activity of the apical cell death caspase Dronc or the proapoptotic Bcl-

78 autonomous induction of proliferation, of an apical cell death caspase.

79 GBE, by tracking cells and quantifying their apical cell deformation over time.

80 Hh is expressed in apical cells, distant from the FSC niche, and diffuses t

81 is no connection between phyllotaxis and the apical cell division pattern indicating a position-depen

82 otaxis (137.5 degrees angle) and an unlinked apical cell division pattern.

83 -based system which links phyllotaxis to the apical cell division pattern.

84 lli are composed of branching filaments with apical cell division, and some Coleochaete species have

85 a cultures of P. patens, growing by filament apical cell division, the proportion of apical (dividing

86 fication initiated exclusively from vertical apical cell divisions, both in 3D culture and in vivo.

87 also induced stratification through vertical apical cell divisions.

88 mplex and the rapid endocytic removal of the apical cell domain.

89 ologs as important regulators of gametophore apical cells downstream of cytokinin.

90 markers to follow the appearance and loss of apical cells during development.

91 on in a non-cell-autonomous manner to induce apical cell enlargement on both sides of their expressio

92 histocompatibility complex (MHC); one is the apical cell expressing both MHC classes I and II, and th

93 sine-1-phosphate (S1P)-dependent entosis and apical cell extrusion.

94 ryos display epidermal hyperplasia, but also apical cell extrusions, during which extruding outer ker

95 s, crb2b and crb3a, promote the formation of apical cell features: photoreceptor inner segments and c

96 PIN-mediated auxin transport regulates apical cell function, leaf initiation, leaf shape, and s

97 hypA or hypB function lead to a cessation of apical cell growth but activated isotropic growth and mi

98 The GUS-negative daughters of apical cells had a strong tendency to contribute primari

99 Apical cells have active mitotic cycles, whereas subapic

100 nsition from a tetrahedral to a wedge-shaped apical cell in the leaf meristem.

101 upported by our description of a tetrahedral apical cell in, to our knowledge, the oldest preserved f

102 In normal eyes, the antibody bound to apical cells in a mosaic pattern, with cells exhibiting

103 reeping body (the thallus), which grows from apical cells in an invaginated "notch." The genetic mech

104 At days 9 and 13, single apical cells in conjunctival epithelium stained with AB/

105 ly development but is then restricted to the apical cells in developing aggregates, which are thought

106 ytes, and the similarities in leaf and shoot apical cells in early diverging groups of ferns add supp

107 We propose that Hh diffuses from apical cells, including cap cells, and regulates the pro

108 Loss of crumbs function disrupts the apical cell junction belt and crumbs overexpression expa

109 trated at the lateral membranes close to the apical cell junction complexes.

110 Llgl1 regulates the formation of apical cell junctions and apicobasal polarity, and we in

111 DAPLE colocalized with MPDZ at apical cell junctions and bound directly to the PDZ3 dom

112 work, we show that NCAM2 is enriched at the apical cell junctions and is required for Nematostella e

113 e targeting of exogenous myc-tagged PMP22 to apical cell junctions in polarized epithelia and to anti

114 the PAR polarity complex (PAR3-PAR6-aPKC) at apical cell junctions leads to efficient assembly of the

115 Yap and the Hippo pathway kinases Lats1/2 at apical cell junctions to induce Yap phosphorylation and

116 (PSD95/DLG1/ZO-1) domain scaffold present at apical cell junctions whose mutation in humans is linked

117 larity complex recruits the protein DAPLE to apical cell junctions, which in turn triggers a two-pron

118 nopus neural plate, being enriched at medial apical cell junctions.

119 birth, ASGP mRNA was diffusely spread in the apical cell layer of both conjunctival and corneal epith

120 oteins that are expressed exclusively in the apical cell layer of the entire tadpole epidermis, which

121 MUC16 mRNA and protein localized to the apical cell layers of the cornea and to the suprabasal r

122 The GalNAc-T4 isoenzyme was found in the apical cell layers, whereas GalNAc-T2 was found in the s

123 ver a form of cell subdivision that abscises apical cell membrane and mediates neuron detachment from

124 e antibody (OE-1) that both localized to the apical cell membrane and significantly inhibited PMN tra

125 irus can infect via receptors located at the apical cell membrane but that the glycocalyx impedes int

126 he purpose of this study was to identify the apical cell membrane component and viral protein that me

127 the formation of inverted cysts, wherein the apical cell membrane faces the cyst exterior, and the ba

128 rming the requirement for SA residues on the apical cell membrane for efficient infectivity of SA-dep

129 studies, we detected endogenous sgk1 at the apical cell membrane of aldosterone-stimulated mpkCCD(c1

130 tein that is asymmetrically localized to the apical cell membrane of dividing cortical progenitor cel

131 ins 2 and 3 can selectively permeabilize the apical cell membrane of epithelial cells in culture to e

132 We track single toxin receptors on the apical cell membrane of MDCK cells with Eu-doped oxide n

133 ore, association of endogenous sgk1 with the apical cell membrane of mpkCCD(c14) cells could be modul

134 ordinated actomyosin dynamics contributes to apical cell membrane organization.

135 cell adhesion molecules, thus regulating the apical cell membrane remodeling and cytoskeletal dynamic

136 tein Cofilin, to regulate F-actin levels and apical cell membrane size, which are required for proper

137 racellular and intracellular surfaces of the apical cell membrane that activate apical Cl(-) conducta

138 at Cby facilitates basal body docking to the apical cell membrane through proper formation of ciliary

139 o examine the transmission of force from the apical cell membrane to the basal cell membrane.

140 PCP protein complexes fail to traffic to the apical cell membrane, although other aspects of apical-b

141 roplicae, a well-developed glycocalyx on the apical cell membrane, and a normal appearance of goblet

142 asal bodies mature but fail to dock with the apical cell membrane, are misorientated and almost compl

143 ropose that the association of sgk1 with the apical cell membrane, where it interacts with ENaC, is a

144 pigmented epithelium (PE), primarily in the apical cell membrane, with minimal extension to the prox

145 diffuse and localized to the basolateral and apical cell membrane.

146 ndogenous sgk1 is functionally active at the apical cell membrane.

147 availability of anionic phospholipids on the apical cell membrane.

148 cAMP-regulated chloride channel localized at apical cell membranes and exists in macromolecular compl

149 However, the expression of CFTR in apical cell membranes or its function as a Cl(-) channel

150 hways: (i) by direct cell-to-cell contact of apical cell membranes with EBV-infected lymphocytes; (ii

151 idney fluid output, expansion of caudal duct apical cell membranes, and occlusion of the caudal prone

152 It was revealed that the apical cells (MHC-positive) were recognized directly by

153 al surface to the rest of the cell or in the apical cell migration and tubulogenesis machinery.

154 However, neither marker accumulates in apical cells of Deltabrk1 filaments.

155 HCLE cultures, MUC16 protein was detected in apical cells of islands of stratified cells.

156 The apical cells of the archegonium, the canal cells, and th

157 Conversely, transgene expression in the apical cells of the colon positive for endogenous u-PAR

158 istry revealed that HCC was localized in the apical cells of the epithelium in the normal conjunctiva

159 Membrane-associated mucins present in the apical cells of the ocular surface epithelium (MUC1, -4,

160 Apical cells of the stratified cultures were the cells t

161 Apical cells of the stratified islands produced MUC16 an

162 ostatic ducts and somewhat less uniformly in apical cells of transition and central zone glands.

163 ds in the subcuticular cavity just above the apical cells of trichomes or emit them into the headspac

164 mponent of the crumbs pathway that regulates apical cell polarity and also may play a role in photore

165 -20 revealed functions in MT dynamics during apical cell polarity formation, spindle assembly, and ax

166 triggered downregulation of PARD6B, loss of apical cell polarity, disorganization of F-actin, and ac

167 reased microvilli density and maintenance of apical cell polarity.

168 n-myosin contraction, and results in loss of apical cell polarity.

169 e presence of a membrane mucin, MUC1, at the apical cell pole, beta-catenin at the apical-lateral mem

170 In a cry1 mutant, expansion of these apical cells proceeded unchecked, reaching rates as high

171 Further divisions of the apical cell produce a peltate trichome with one basal ce

172 Estimates of the density of the apical cell range from 1.004 to 1.085.

173 ay inherit the radial glial fibre, while the apical cell sequesters the majority of the Numb protein.

174 sarcomeres concomitantly impacts changes in apical cell shape and tissue geometry.

175 CRIB plays a critical role in the control of apical cell shape, as well as in the basoapical polariza

176 equired for SCRIB function in the control of apical cell shape.

177 We investigated the apical cell-shape changes that characterize amnioserosa

178 We find that apical cell shapes are abnormal in sdk mutants, suggesti

179 ng and extending tissue, causes the abnormal apical cell shapes in sdk mutant embryos.

180 of BPGM was concentrated exclusively in the apical cell side, in direct proximity to the maternal ci

181 n apical release of progeny virus, increased apical cell sloughing, apoptosis, and occasional syncyti

182 Individual cells in the two-apical-cell stage embryo responding to heat shock produc

183 by inducing genetic chimerism during the two-apical-cell stage of embryogenesis to determine if the o

184 e report that virus attachment to DAF on the apical cell surface activates Abl kinase, triggering Rac

185 but the mechanism by which changes near the apical cell surface affect changes along the entire apic

186 TPase subunits, showed colocalization at the apical cell surface and coassociation by immunoprecipita

187 of the ZA but is distributed over the entire apical cell surface and concentrated in the immediate vi

188 Virus binds to VLA-2 on the apical cell surface and moves rapidly to early endosomes

189 emonstrated that hSVCT1 was expressed at the apical cell surface and video rate measurements revealed

190 isms that restrict these determinants to the apical cell surface are unknown.

191 Expression was about sixfold greater on the apical cell surface as assessed biochemically by selecti

192 inding protein filamin A, potentially at the apical cell surface associated with the basal body.

193 centrated in actin-rich protrusions from the apical cell surface colocalized with the RNA-binding ret

194 It is proposed that the marginal zone of the apical cell surface contains a crumbs- and stardust-depe

195 in tubular fluid and anions anchored on the apical cell surface could determine whether a crystal bi

196 Nucleolin was enriched on the apical cell surface domain of A549 cells, and HPIV-3 int

197 piregulin (EREG) from the basolateral to the apical cell surface drives transformation.

198 e protein and chitin matrix packaging at the apical cell surface during development.

199 tilization tubule, a mating structure at the apical cell surface in gametes.

200 The apical cell surface is locally perturbed by atomic force

201 bble-like cysts that selectively incorporate apical cell surface markers.

202 p-ERK was localized at the apical cell surface of bronchiolar and alveolar type II

203 -1 is a transmembrane mucin expressed at the apical cell surface of mouse uterine epithelial cells (U

204 ass are preferentially exocytosed toward the apical cell surface of polarized cells, include antigens

205 ution of functional hSVCT1 expression at the apical cell surface of polarized epithelia and define an

206 In vivo, T-cadherin was detected on the apical cell surface of the chick intestinal epithelium.

207 receptor tyrosine phosphatase present on the apical cell surface of the glomerular podocyte.

208 t with defective recycling of megalin to the apical cell surface of the proximal tubules and thus dec

209 t of the mechanism of mucin removal from the apical cell surface of UEC.

210 stalline arrays of uroplakin proteins to the apical cell surface of urothelial umbrella cells.

211 g with ezrin and alpha(3)beta(1) integrin in apical cell surface protrusions.

212 of the F-actin cytoskeleton similarly affect apical cell surface remodeling and lumen formation.

213 th additional N-glycans redistributed to the apical cell surface similar to that of rat FcRn.

214 Efficient transduction of AEC from the apical cell surface supports the feasibility of using VS

215 ctive tract, and gut, requires a specialized apical cell surface that prevents adhesion.

216 s preferentially secreted RANTES through the apical cell surface thereby establishing a chemical grad

217 te proteins and enzymes that assemble at the apical cell surface to provide epithelial integrity and

218 glutinin from the trans-Golgi network to the apical cell surface was severely inhibited in cells over

219 ha- and gamma-ENaC subunits that reached the apical cell surface were considerably longer (t(12) > 24

220 tinal epithelial cells depends on DAF at the apical cell surface, and expression of human DAF on muri

221 its heterodimerization partner ErbB3, to the apical cell surface, effectively segregating the two rec

222 I) formed biofilms in close proximity to the apical cell surface, followed by invasion and destructio

223 Sec23 and Sec24CD, which traffic Crb to the apical cell surface, partially rescue border cell cluste

224 ion by binding to and sequestering Hh on the apical cell surface, thereby inhibiting Hh diffusion.

225 beta1-integrin on microprotrusions from the apical cell surface.

226 l and delivery sites at the periphery of the apical cell surface.

227 anosomes to mature and to associate with the apical cell surface.

228 l caused Polycystin-2 mislocalization to the apical cell surface.

229 ng that at least a portion is exposed on the apical cell surface.

230 ed for the efficient targeting of GCC to the apical cell surface.

231 onductance regulator chloride channel at the apical cell surface.

232 s that control the expression of ENaC at the apical cell surface.

233 e newly synthesized protein delivered to the apical cell surface.

234 ly synthesized endolyn were delivered to the apical cell surface.

235 ased the fluorescent labeling of ENaC at the apical cell surface.

236 ecting a set of force curves over the entire apical cell surface.

237 eta2 subunits accumulated selectively in the apical cell surface.

238 e necessary for sorting hemagglutinin to the apical cell surface.

239 or that there are inhibitory factors on the apical cell surface.

240 ic from the trans-Golgi network (TGN) to the apical cell surface.

241 of large patches (or plaques) at or near the apical cell surface.

242 ic of secretory proteins from the TGN to the apical cell surface.

243 teins from both viruses co-localizing at the apical cell surface.

244 ithelia that can withstand freshwater on the apical cell surface.

245 ng factor (DAF), a receptor expressed on the apical cell surface.

246 mbly zone that controls aECM assembly at the apical cell surface.

247 and V159G substitutions redirect EREG to the apical cell surface.

248 nisms to enter the cell through the lumenal (apical) cell surface.

249 TLR7, and TLR9) are mostly expressed on the apical cell surfaces of epithelial cells in the human tr

250 Syntaxin 1A is seen near the apical cell surfaces of human bronchial airway epitheliu

251 folding is characterized by constriction of apical cell surfaces, and the resulting cell shape chang

252 When applied to apical cell surfaces, wild type toxins elicited a brisk

253 atio, and periodicity in the organization of apical cell surfaces.

254 It was observed that in most EMTs, the apical cell tail is retracted cleanly from the lumen of

255 we find that Cdc42 is critical for limiting apical cell tension by antagonizing Rho activity at AJs.

256 o contributes, downstream of Rho1 to sustain apical cell tension.

257 egrity independent of its role in sustaining apical cell tension.

258 ears ago, coinciding with the development of apical cells that divide in three planes.

259 s in BRK1 being localized only in the tip of apical cells, the exclusive site of cell extension and d

260 In addition, SIK1 fails to partition the apical cell; thus, nuclei are not likely to arrest mitos

261 otic shocks are propagated globally from the apical cell tips, enabling fine-tuned cell volume regula

262 ), suggesting that the higher sensitivity of apical cells to salt is not related to either enhanced N

263 mediated accumulation of auxin in the medial-apical cells undergoing symmetry transition is required

264 The apical cells uniformly cover the surface of the tadpole

265 was the most important factor in determining apical cell uptake of lutein, with cookies and muffins e

266 Apical cells vary in length and number of nuclei, wherea

267 f an exogenous PME induces thickening of the apical cell wall and inhibits pollen tube growth.

268 es to the focused secretion of pectin to the apical cell wall and, thus, to the polarized growth of t

269 interference contrast (DIC), (2) changes in apical cell wall fluorescence in cells stained with prop

270 We obtained evidence that apical cell wall synthesis occurs through examining the

271 essation of elongation and thickening of the apical cell wall.

272 ch constitute the principal component of the apical cell wall.

273 at both types of media penetrate through the apical cell wall.

274 respond to osmotic stress by softening their apical cell walls, sustaining extension growth despite r

275 We predict that a tetrahedral leaf apical cell was likely ancestral in circinatophytes, des

276 The act7-4 root apical cells were not in straight files and contained ob

277 leaky; the intercellular spaces between the apical cells were penetrated by sulfosuccinimidyl-6-(bio

278 y tip growth that is restricted to the first apical cell, where turgor pressure, exocytosis and endoc

279 of actin is observed at the tip of wild-type apical cells, whereas in Deltabrk1, smaller, more distin

280 e cells and more numerous apoptotic condylar apical cells, while chondroprogenitors displayed higher

281 -dimensional (3D) growth: the acquisition of apical cells with the capacity to rotate the plane of ce