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1 the basolateral side and secrete them at the apical membrane.
2 tubules and stretching and stiffening of the apical membrane.
3 icking pathways, including polar delivery to apical membrane.
4 xpressed at the basolateral membrane and the apical membrane.
5 KC/Cdc42 polarity complex to localize to the apical membrane.
6 cells and MTOC function is reassigned to the apical membrane.
7 ses the basolateral membrane en route to the apical membrane.
8 tabolism and normal GLUT5 trafficking to the apical membrane.
9 g at AREs and carrier vesicle docking at the apical membrane.
10 tween intracellular storage vesicles and the apical membrane.
11 riggers a reduction in CFTR abundance at the apical membrane.
12 recruitment of Yrt restricts the size of the apical membrane.
13 gulates the levels and asymmetry of D at the apical membrane.
14 e small GTPase Rab11a before arriving at the apical membrane.
15 al and CF donor lungs, CTSB localized to the apical membrane.
16 lops distal appendages that anchor it to the apical membrane.
17 teins that would normally be targeted to the apical membrane.
18 , as well as physically anchoring Dia to the apical membrane.
19 basal to apical, forming the midbody at the apical membrane.
20 lular distribution of the channel toward the apical membrane.
21 umber, shape and positioning relative to the apical membrane.
22 of vesicles from their storage areas to the apical membrane.
23 cient and distinct restriction of Dia to the apical membrane.
24 junctions and promoted CD59 uptake from the apical membrane.
25 zrin to continually bias its function to the apical membrane.
26 e migrating centrosome onto the lateral then apical membrane.
27 he rate at which ENaC was retrieved from the apical membrane.
28 ial for bile acid-dependent bile flow at the apical membrane.
29 ed JAM-A moved to the brain endothelial cell apical membrane.
30 was required to restrict its function to the apical membrane.
31 PDZK1 in the stabilization of NaPi-2c in the apical membrane.
32 GPR91 was expressed in RPE but only in the apical membrane.
33 alization using a specific marker of the RPE apical membrane.
34 nfirmed the formation of inclusions from the apical membrane.
35 the proton pumping V-ATPase located in their apical membrane.
36 esulted in accumulation of inclusions at the apical membrane.
37 complexes preferentially takes place at the apical membrane.
38 ansporter A1 and promoted its trafficking to apical membrane.
39 ) transport by altering ENaC activity in the apical membrane.
40 2 translocation from storage vesicles to the apical membrane.
41 imulates the NKCC1 co-transporter at the CPE apical membrane.
42 ches develop bubble-like cysts with enlarged apical membranes.
43 cell retained tight junctions and segregated apical membranes.
44 lateral membranes and the basolateral to the apical membranes.
45 trols anion secretion across epithelial cell apical membranes.
46 ional claudin molecules such as claudin-4 at apical membranes.
48 x in epithelial cells, excludes Lgl from the apical membrane, a crucial step in the establishment of
49 the proton pumping V-ATPase located in their apical membrane, a process that is activated by luminal
50 tion is part of a process that controls AQP2 apical membrane abundance in a vasopressin-dependent man
51 A2B purinergic P1 receptors induced V-ATPase apical membrane accumulation in medullary A-ICs but not
55 the Plasmodium falciparum vaccine candidate apical membrane Ag-1 (AMA1) in HIV-infected and uninfect
57 cation of the proton pump, HK-ATPase, to the apical membrane along with activation of apical chloride
58 tionally, Moe mutant cells lost Crb from the apical membrane and accumulated excess Crb at the MZ, su
59 g partner of EXC-9, is also localized to the apical membrane and affects apical actin placement and R
60 s open in response to ATP stimulation at the apical membrane and allow K(+) flux to the airway surfac
61 s active Cdc42 accumulates at the developing apical membrane and cell-cell contacts, independently of
62 of the sub-cellular components including the apical membrane and cytoplasm of the cell at the tissue
63 e stiffness of the intact, living urothelial apical membrane and found it to be highly deformable, ev
66 sms leading to myosin II accumulation at the apical membrane and its exclusion from other membranes a
67 gel beads allowing superficial access to the apical membrane and making the model more physiological.
68 X-809 treatment increased CFTR levels at the apical membrane and reduced its association with the end
69 acidified resorption compartment between the apical membrane and the bone surface to solubilize hydro
70 nslocation to the renal proximal tubule cell apical membrane and the internalization of Na(+)-H(+) ex
71 required to maintain the organization of the apical membrane and the physiological activity of the la
72 that Cad99C serves as a link between the SG apical membrane and the secreted apical ECM component(s)
74 s and cytoplasm in undifferentiated cells to apical membranes and microvilli in differentiated monola
75 ecting sequestration of GUCY2C to intestinal apical membranes and segregation of mucosal and systemic
76 amined by quantifying recovered BCG from the apical, membrane and basolateral fractions over time.
77 The active form of mDia1 localized to the apical membrane, and introduction of an active form of m
78 and displaced from M025alpha and NCC at the apical membrane, and redistributes to dense punctate str
79 he expression of FLVCR was restricted to the apical membrane, and the expression of BCRP and PCFT was
82 centrosomes and nuclei move near the future apical membranes, and the postmitotic centrosomes lose a
83 smembrane conductance regulator (CFTR) is an apical membrane anion channel that is widely expressed i
85 host outer membrane and serve as ligands for apical membrane antigen (AMA) family surface proteins di
87 iparum vaccine candidate antigens, including apical membrane antigen 1 (AMA-1), circumsporozoite prot
88 e that is based on the 3D7 clone sequence of apical membrane antigen 1 (AMA1) and formulated in Adjuv
89 ), cysteine-rich protective antigen (CyRPA), apical membrane antigen 1 (AMA1) and rhoptry neck protei
90 A), a blood-stage candidate vaccine based on apical membrane antigen 1 (AMA1) from the 3D7 strain of
96 mic domain of the essential invasion adhesin apical membrane antigen 1 (AMA1) regulates erythrocyte i
97 at includes a type I membrane protein called apical membrane antigen 1 (AMA1) to invade host cells.
98 ), erythrocyte binding antigen 175 (EBA175), apical membrane antigen 1 (AMA1), and parasite lysate.
99 rotein 2 (RON2) to the hydrophobic groove of apical membrane antigen 1 (AMA1), triggering junction fo
101 orts, and that changes in antibody levels to Apical Membrane Antigen 1 suggested a decrease in transm
103 e antigens from the P. falciparum 3D7 clone (apical membrane antigen 1, AMA1-3D7; merozoite surface p
106 umsporozoite protein, liver-stage antigen-1, apical membrane antigen-1, and merozoite surface protein
108 umsporozoite protein, liver-stage antigen 1, apical-membrane antigen 1 (AMA-1), and merozoite surface
109 Steady-state surface NKCC2 levels in the apical membrane are maintained by a balance between exoc
111 initial vascular cords of endothelial cells, apical membranes are established and become cleared of c
112 Drosophila ovarian follicle cell epithelium, apical membranes are specified by Crumbs (Crb), Stardust
114 s on trafficking to, and insertion into, the apical membrane, as well as on phosphorylation of conser
115 Cad99C or SAS causes a dramatic increase in apical membrane at the expense of other membrane domains
116 ivation increased renal proximal tubule cell apical membrane AT2R protein (P<0.001) without changing
119 arity by recruiting polarity proteins to the apical membrane, but how a change in protein localizatio
120 tightly packed arrays of microvilli in their apical membrane, but the fate of these microvilli is rel
124 4 revealed the presence of subdomains on the apical membrane characterized by extensive exocytosis.
125 otease-activated receptor 2 activates airway apical membrane chloride permeability and increases cili
126 low-level nitric oxide production, increases apical membrane Cl(-) permeability approximately 3-5-fol
127 t the HAT-7 cells were polarized with a high apical membrane CO2 permeability and vigorous basolatera
128 arized acini lipids were more ordered at the apical membranes compared to basal membranes, and that a
129 nal crypt enterocytes PDK1 distributes to an apical membrane compartment comprising plasma membrane a
131 mice that anchoring of the centrosome to the apical membrane controls the mechanical properties of co
132 ll as repressing Yki by recruiting Ex to the apical membrane, Crb promotes phosphorylation-dependent
133 ting beta(Heavy)-Spectrin and MyosinV to the apical membrane, Crumbs maintains the Rab6-, Rab11- and
134 mental studies, however, have focused on the apical membrane, despite the fact that ion transport acr
135 also known as Mpp5), a core component of the apical membrane-determining CRB complex in the nephron.
137 1(+) vesicles containing PCP proteins to the apical membrane during the initiation of planar cell pol
139 b, a selective EGFR inhibitor, enhanced AQP2 apical membrane expression in collecting duct principal
140 hydrolase virulence factor that reduces the apical membrane expression of ABC transporters such as t
143 oteins are important in epithelial polarity, apical membrane formation, and tight junction (TJ) assem
144 s like the hair bundle and ensuring that the apical membrane forms appropriately around the stereocil
145 increase or decrease ENaC expression at the apical membrane; forskolin increased the association of
148 multaneously targeting PI3K and Tiam1 to the apical membrane has a synergistic effect on membrane rem
149 or (FcRn) located at the brush border of the apical membrane has been implicated as the "receptor" me
150 Crumbs (Crb) is a conserved determinant of apical membrane identity that regulates epithelial morph
151 d to tight junctions, is sufficient to alter apical membrane identity through its interactions with p
153 al recycling endosomes (ARE) and reaches the apical membrane in a microtubule- and Rab11-dependent ma
154 pressed at the ATP release site, such as the apical membrane in airway epithelial cells; (3) the phar
155 ssigned to non-centrosomal sites such as the apical membrane in epithelial cells, the nuclear envelop
156 urthermore, Kuzbanian is not enriched at the apical membrane in i mp mutants, accumulating instead in
160 from the tight junction but relocated to the apical membrane in renal epithelial cells because of dim
164 H/K-ATPase-rich tubulovesicles (TVs) toward apical membranes in response to histamine stimulation vi
165 ectively, in maturation and targeting to the apical membrane, in polarized Madin-Darby Canine Kidney
167 eting of apical endosomes to the midbody and apical membrane initiation site (AMIS) during lumenogene
168 urface and initiating its transcytosis to an apical membrane initiation site for lumen formation.
170 rtures are formed by fusion of the basal and apical membranes into a tunnel that spans the height of
171 ent of MTOC function from centrosomes to the apical membrane is associated with a physical hand-off o
174 initially developed normally, but the cell's apical membrane lifted away from the cuticular plate, an
176 he role of AP-2 in the maintenance of proper apical membrane lipid and cell wall composition is furth
178 Furthermore, knockdown of PHLPP altered the apical membrane localization of aPKCs and reduced the fo
179 ly reduced colocalization of KCNN4c with the apical membrane marker wheat germ agglutinin in T84WT ce
180 n caused by defective anion transport at the apical membrane may contribute to the excessive and pers
181 osomal microtubules, and its delivery to the apical membrane mediated by the small GTPase rab11a.
182 cking component mislocalizes the same set of apical membrane molecules basolaterally, including the p
185 oteins are more effectively processed to the apical membrane of airway epithelia than human DeltaF508
186 cretory sorting of the auxin carrier PIN2 to apical membrane of Arabidopsis root epithelial cells.
187 es bile secretion and other functions at the apical membrane of biliary epithelial cells (i.e., chola
190 tubules, distal convoluted tubules, and the apical membrane of collecting duct A-type intercalated c
191 In functional studies, hTf uptake across the apical membrane of cultured PT epithelial cell (PTEC) mo
192 ast to wild-type Ncc, which localized to the apical membrane of distal convoluted tubule cells, T58M
194 tl) and Dachsous (HyDs) that localize at the apical membrane of ectodermal epithelial cells and are p
199 tial for the stability of myelin, and at the apical membrane of epithelial cells, where it has a crit
200 DUOX2), a hydrogen-peroxide generator at the apical membrane of gastrointestinal epithelia, is up-reg
201 roinflammatory P2Y14 receptor located on the apical membrane of ICs or ablation of the gene encoding
202 egulation by GPCRs that are expressed at the apical membrane of intestinal and airway epithelia.
203 ts with MVID lacked MYO5B at the base of the apical membrane of intestinal cells; instead MYO5B was i
205 Unlike in the DCT, OSR1 remains at the TAL apical membrane of KO mice where it is accompanied by an
207 imary cilia, which are positioned within the apical membrane of neuroepithelial progenitors, we hypot
208 ssociated with a multiprotein complex at the apical membrane of normal mouse cholangiocytes, with pro
212 al disease by binding ganglioside GM1 on the apical membrane of polarized intestinal epithelial cells
213 with clathrin, but not with caveolin, at the apical membrane of PTECs, which determines clathrin-medi
215 lial sodium channel (ENaC) is present in the apical membrane of sodium-absorbing vertebrate epithelia
216 omolecular complex within lipid rafts at the apical membrane of surface and glandular airway epitheli
217 arrier to CO(2) resides in the umbrella cell apical membrane of the bladder with its dense array of u
218 increased the ROMK channel intensity in the apical membrane of the collecting tubule in Romk1(+/+),
219 c lines showed that Cftr is localized to the apical membrane of the epithelial cells in KV during lum
220 tood, nonheme iron is transported across the apical membrane of the intestinal enterocyte by divalent
221 ely activate type 2 chloride channels in the apical membrane of the intestinal epithelial cells leadi
222 unctional SGLT2 transporters detected in the apical membrane of the proximal tubule but not detected
224 P) 2B1 (OATP-B; SLCO2B1) is expressed in the apical membrane of the small intestine and the hepatocyt
225 regulatory molecule, Cab39/MO25alpha, at the apical membrane of the thick ascending limb (TAL) and di
226 stry, aquaporin 2 was concentrated along the apical membrane of tubular cells with ET but not PA, and
227 ns were released from or associated with the apical membranes of ciliated, nonciliated, and mucin-sec
228 cission midbody remnants are observed at the apical membranes of daughter cells and are much more abu
229 kidney tissue showed expression of 24p3R in apical membranes of distal tubules and collecting ducts,
230 y normal localization, PIN2 is depleted from apical membranes of epidermal cells and shows basal to a
231 membrane conductance regulator (CFTR) at the apical membranes of epithelial cells have not yet been f
232 g assembly before they are inserted into the apical membranes of epithelial cells, and maximal activi
233 f PC2 channel function from a preparation of apical membranes of human syncytiotrophoblast (PC2hst) r
236 2 is expressed in several tissues, including apical membranes of small intestinal epithelial cells.
237 in is reduced 23%, NHE2 remains localized to apical membranes of surface epithelium, and NHE1 protein
239 iltered by the kidney, binds to SGLT2 in the apical membranes of the early proximal tubule, and is su
240 d cellular mechanism to create and model the apical membranes of the two fundamental types of photore
242 ing Cdc42 clustering, by tethering it to the apical membrane or lowering its diffusion, restores norm
243 e cell surface, but fails to localize at the apical membrane patch specialized for fusion and fails t
244 ss of the shell generated by adhesion of the apical membrane patches to the pore rim and the apparent
245 in the facilitated iodide efflux across the apical membrane (PDS), the organification of iodide with
246 ndings, we propose a trafficking pathway for apical membrane polarity and lumen morphogenesis that im
247 daptor protein 1 (AP-1)-dependent intestinal apical membrane polarity and polarity-dependent localiza
249 , this network regulates lateral mobility of apical membrane probes such as integrins or epidermal gr
250 ested this model using the Toxoplasma gondii apical membrane protein 1 (TgAMA1), which binds to aldol
254 in-based adhesion complexes to remodel their apical membrane protrusions into organized functional ar
255 of the endothelium through the formation of apical membrane protrusions that embrace adherent leukoc
256 reduced pendrin's relative abundance in the apical membrane region and pendrin abundance per cell wh
257 abundance and its relative abundance in the apical membrane region over a wide range in serum potass
261 rupts the anchorage of the centrosome to the apical membrane, resulting in the disorganization of mic
262 The mis-localization of receptors to the apical membrane results in ectopic BMP signaling in the
263 ll-attached patch recording on the hair-cell apical membrane revealed, after BAPTA treatment or durin
264 ngly, patch clamp studies on cortical tubule apical membranes revealed that mTOR inhibition markedly
266 of a novel, Moesin- and PI(4,5)P(2)-enriched apical membrane sac containing microvilli-like structure
268 re, we scrutinized the elastic properties of apical membranes separated from living cells and attache
269 bacterial adherence, from basolateral to the apical membrane sides in a microtubule- and Stim1-depend
271 Loss of this regulation results in increased apical membrane size with scattered apical recycling end
274 'bare zone', a microvilli-free sub-region of apical membrane specified by the Insc-LGN-Galphai protei
275 del intestinal epithelium, the conversion of apical membrane sphingomyelin to ceramide by exogenous b
276 ppeared more dispersed, and the intensity of apical membrane staining for AQP2 was reduced significan
277 n array of microvilli that serves to amplify apical membrane surface area and increase functional cap
278 letal polarization to control the developing apical membrane surface during blood vessel tubulogenesi
280 th receptors was significantly faster in the apical membrane than in the basal membrane, suggesting d
282 nge factor that is recruited by ezrin to the apical membrane, that is enriched at a marginal zone api
283 s TRPV4 trafficking and translocation to the apical membrane, the PKC-dependent pathway increases the
284 nating abscission with delamination from the apical membrane; timing of neurogenesis and its indirect
285 have evolved unique structures to expand the apical membrane to accommodate the phototransduction mac
288 n of syntaxin 2 and 5' nucleotidase from the apical membrane to subapical puncta, whereas multidrug r
289 orphogenesis and plays a role in linking the apical membrane to the underlying ezrin-containing cytos
290 caused localization of intestinal SR-B1 from apical membranes to intracellular organelles and reduced
292 rt and further define the classical model of apical membrane traffic at the tip of elongating pollen
296 e (KHK), as well as GLUT5 trafficking to the apical membrane via the Ras-related protein-in-brain 11
297 r Cl(-) /HCO3(-) exchange via SLC26A6 at the apical membrane were able to support a HCO3(-) -rich sec
298 than threefold brighter than the surrounding apical membrane when the densities of fluorescently labe
299 ts in dividing cells become localized to the apical membrane, which becomes highly enriched in microt
300 roscopy examination revealed that hepatocyte apical membrane with microvilli substantially extended i