ライフサイエンスコーパス: apical surface

1 Aurora B has a role in the formation of the apical surface.

2 diate fusion of transcytotic vesicles at the apical surface.

3 y, decreasing the amount of NKCC2 at the TAL apical surface.

4 the stereocilia that project from the cells' apical surface.

5 otein VAMP3, and they co-localize at the TAL apical surface.

6 ed bacteria are trafficked to and across the apical surface.

7 microvilli to become motile over the dorsal/apical surface.

8 they co-localize in discrete domains at the apical surface.

9 he proper positioning of motile cilia on the apical surface.

10 sition of the substrate protein on the GroEL apical surface.

11 gth of the gut and do not share a continuous apical surface.

12 entify the mechanisms that target Dia to the apical surface.

13 s insufficient to reroute this mutant to the apical surface.

14 f a primary cilium, the kinocilium, at their apical surface.

15 e with ciliated and nonciliated cells on its apical surface.

16 e together with these foci toward the future apical surface.

17 corresponding hinge areas of the urothelial apical surface.

18 ed network of ciliary basal bodies below the apical surface.

19 e by which uroplakins were inserted into the apical surface.

20 n decreased the association of sgk1 with the apical surface.

21 mechanotransduction organelle located on the apical surface.

22 ly to the circumference of the cell near its apical surface.

23 comitans when the bacteria were added to the apical surface.

24 al domains and assemble junctions near their apical surface.

25 tor H regulates complement activation on the apical surface.

26 racterized by effacement and blebbing of its apical surface.

27 ically inhibited nuclear movement toward the apical surface.

28 into foci and for foci to accumulate at the apical surface.

29 e hair bundle that protrudes from the cell's apical surface.

30 a brush border containing microvilli on the apical surface.

31 e furrow, most re-establish contact with the apical surface.

32 ial plaques) covering >90% of the urothelial apical surface.

33 issorted CAR from recycling endosomes to the apical surface.

34 the G(M1), integrin, microvillus-containing apical surface.

35 phase plates oriented perpendicularly to the apical surface.

36 t that CAIV may have a role in buffering the apical surface.

37 to maintain cytoskeletal flexibility at the apical surface.

38 tribute to the antiadhesive character of the apical surface.

39 tion of extracellular vesicle cargoes to the apical surface.

40 without altering beta-ENaC expression at the apical surface.

41 mit reshaping of actomyosin networks and the apical surface.

42 nctions enables S. flexneri invasion via the apical surface.

43 without altering beta-ENaC expression at the apical surface.

44 with the basolateral surface compared to the apical surface.

45 , either close to or in association with the apical surface.

46 relocalize proteins from the cytosol to the apical surface.

47 a large pre-apical compartment (PAC) to the apical surface.

48 e primary cilium at the abneural edge of the apical surface.

49 es its constitutive exocytic delivery to the apical surface.

50 transferring MeV to HAE when applied to the apical surface.

51 ce to cell membrane, causing an expansion of apical surfaces.

52 cal tension without substantial shrinking of apical surfaces.

53 derm is driven by the pulsed constriction of apical surfaces.

54 ctivated GPCR (Oxgr1) increased on the PP-IC apical surface, allowing paracrine delivery of alpha-KG

55 ized trafficking of podocalyxin to the early apical surface--an important event in vascular lumenogen

56 ystem creates microaerobic conditions at the apical surface and aerobic conditions at the basolateral

57 bules, endolyn is variously localized to the apical surface and endosomal/lysosomal compartments.

58 uid absorption to prevent dehydration of the apical surface and increased cilia beating in these epit

59 actin-filament-rich structures at the dorsal-apical surface and induces structures with greater actin

60 Transcellular dendrites scanned the M-cell apical surface and the gut luminal content; they were ab

61 ecular mechanisms by which NKCC2 reaches the apical surface and their role in renal function and main

62 lium (RPE), anomalously expressed CAR at the apical surface and was highly susceptible to adenovirus

63 The remnant then moves along the apical surface and, once proximal to the centrosome at t

64 Sbf localizes to tubular, apical surfaces and associates with Rab35, where it prom

65 undred actin filaments that arise from their apical surfaces and that bear the mechanotransduction ap

66 d cell-cell adhesions had nuclei with curved apical surfaces and variable heights.

67 e PfCHT1) are both localized on the ookinete apical surface, and both are present in micronemes.

68 lateral surface than after adsorption to the apical surface, and it was dependent on JAM-A.

69 to alter the geometry of cell shapes at the apical surface, and that cell shape then determines the

70 totic spindle, mispositioning of the nascent apical surface, and ultimately, the formation of aberran

71 ivering fusiform vesicles, as well as at the apical surface; and 4) the hinge-associated MAL may play

72 regulate the presence of microvilli on their apical surface are largely unknown.

73 echanisms targeting membrane proteins to the apical surface are still poorly understood.

74 s, amnioserosa cells undergo oscillations in apical surface area.

75 essed in epidermal cells and secreted to the apical surface as a putative component of the embryonic

76 characterize forces driving emergence of an apical surface as single nascent cells are added to a ve

77 g process involving the de novo formation of apical surface at secondary lumina, and that radial inte

78 RSV was shed exclusively from the apical surface at titers consistent with those in airway

79 ed basolateral proteins such as VSV-G to the apical surface, but do not cause mis-sorting of membrane

80 es establish efficient infection through the apical surface, but efficient spread and apical release

81 Depletion of extracellular Ca(2+) at the apical surface, but not basolateral surface, also preven

82 myosin (NMY-2Colon, two colonsGFP) at their apical surfaces, but in either sax-7(eq1) or hmr-1(RNAi)

83 signaling involved in planar polarity at the apical surface can influence position-dependent AZ prope

84 in VDCs under microaerobic conditions at the apical surface, compared to results under aerobic condit

85 n and neurogenesis was shifted away from the apical surface, consistent with increased pro-proliferat

86 e hypothesized that NKCC2 endocytosis at the apical surface depends on dynamin-2 and clathrin.

87 demonstrate that Wg is endocytosed from the apical surface devoid of DFz2 via a dynamin-independent

88 Stresses applied via integrins at the apical surface directly displaced podosomes near the bas

89 suggested crowding from cell division at the apical surface drives basalward motion.

90 hat line the intestinal tract, remodel their apical surface during differentiation to form a brush bo

91 tiguous duct that largely separates from the apical surface during PAC fusion.

92 gesting that ClpA can rotate around the ClpP apical surface during processive steps of translocation

93 ffic of vesicles to locations of lengthening apical surface during single-celled tubule development.

94 ximal to the centrosome at the center of the apical surface, enables cilium formation.

95 align at metaphase in the long length of the apical surface except in cells undergoing unequal cleava

96 finding that Rfx2 cell-autonomously controls apical surface expansion in nascent MCCs.

97 naling lead to inverted polarity so that the apical surfaces face the surrounding ECM.

98 gate how dying cells specifically indent the apical surface, finding that apical actomyosin cables co

99 /Rab35 appears to prefigure and organize the apical surface for efficient Myosin function.

100 tereociliary bundles that project from their apical surface, forming a characteristic graded 'stairca

101 pparently significantly lower remains at the apical surface, from where its uptake occurs.

102 nocilia, or bind directly to the hair cells' apical surface if cilia are absent [MZovl injected with

103 ltiple pericentrin-stained centrioles at the apical surface, (ii) expression of transcription factor

104 ring cell division to correctly position the apical surface in a growing epithelial structure.

105 ells undergo epithelialization and create an apical surface in contact with a cavity, a fundamental e

106 e cell periphery in early embryos and at the apical surface in pharyngeal and intestinal epithelial c

107 During mitosis, Pins is mislocalized to the apical surface in the absence of Par3 or by inhibition o

108 tself sufficient to reroute a protein to the apical surface in the presence of a strong basolateral s

109 Their apical surface, in contact with aqueous humor is hexagon

110 lation to the amount of virus applied to the apical surface, indicating transcytosis efficiency was c

111 rteporfin, a nuclear Yap inhibitor, restored apical surface integrity, normalized proliferation, atte

112 old) reduction in HSV-1 released through the apical surface into the extracellular environment.

113 f the SG epithelium, loss of AdamTS-A causes apical surface irregularities and cell elongation defect

114 toreceptor outer segments (POSs) and the RPE apical surface is compromised.

115 , optic vesicle cells shorten, drawing their apical surfaces laterally relative to the basal lamina,

116 oss NCI-H441 lung epithelial cell layers and apical surface liquid (ASL) volumes are coupled to dexam

117 hil elastase and myeloperoxidase activity in apical surface media than in media with mock-infected ai

118 ), sub-clones were assessed for growth rate, apical surface morphology, epithelial barrier function a

119 e conclude that cAMP stimulates steady-state apical surface NKCC2 by stimulating exocytic insertion a

120 Confocal imaging of apical surface NKCC2 in isolated perfused TALs confirmed

121 NKCC2 endocytosis and maintain steady-state apical surface NKCC2 in native THALs.

122 cted modules: "NPHP1-4-8" functioning at the apical surface, "NPHP5-6" at centrosomes, and "MKS" link

123 accumulation of V-ATPase proton pumps at the apical surface of A-ICs in KO mice compared to controls.

124 minoglycan hyaluronic acid is present on the apical surface of airway epithelial cells.

125 lament-rich mechanosensory structures at the apical surface of auditory and vestibular hair cells.

126 Par6B localizes to the apical surface of Caco-2 cysts and is required to recrui

127 bule-based structures that protrude from the apical surface of cells to mediate motility, transport,

128 le information on cortex organization at the apical surface of cells.

129 pic actin bundles are seen across the entire apical surface of cells.

130 hich are observed at excessive levels at the apical surface of CF airway epithelial cells.

131 were expressed at 32 receptors/mum(2) on the apical surface of choroid plexus epithelial cells.

132 ryos, we show that GAS2L2 is abundant at the apical surface of ciliated cells, where it localizes wit

133 ted in exposure of terminal galactose on the apical surface of conducting airway epithelial cells, as

134 the prevention of bacterial adherence to the apical surface of corneal epithelial cells and suggest t

135 ad decreased ependymal cells and Mpp5 at the apical surface of cortical ventricular zone compared wit

136 Static adhesion assays showed that the apical surface of differentiated HCLE cells expressing M

137 As the apical surface of differentiating epithelial cells is cr

138 gration - the movement of nuclei towards the apical surface of dividing epithelial cells - is mechani

139 ture showed the HS binding site to be at the apical surface of E2, with variants affecting the electr

140 At the apical surface of each hair cell, the proteins display p

141 raphy of kidney showed F-Dapa binding to the apical surface of early proximal tubules.

142 positioning them in direct contact with the apical surface of either intercalated or principal cells

143 t in the endothelial glycocalyx covering the apical surface of endothelial cells.

144 to transport LPL from the basolateral to the apical surface of endothelial cells.

145 ween SIgA and CD71 or CD71 and Tgase2 at the apical surface of enterocytes in biopsy samples and mono

146 GPAT3 was abundantly expressed in the apical surface of enterocytes in the small intestine.

147 mation beneath the infecting bacteria on the apical surface of enterocytes.

148 in and localize to cell junction area at the apical surface of epithelia.

149 ne-associated mucins, MUC1 and MUC16, on the apical surface of epithelial cells and that both mucins

150 te that microtubule alignment underneath the apical surface of epithelial cells follows cell shape.

151 the actin core of nascent microvilli on the apical surface of epithelial cells underlies their motil

152 the delivery of polymeric IgA and IgM to the apical surface of epithelial cells via transcytosis.

153 The immune defense is initiated at the apical surface of epithelial cells where the N-terminal

154 at that tensile forces are stored across the apical surface of epithelial cells, and anillin promotes

155 s associated with myosin accumulation at the apical surface of epithelial cells, as seen in the verte

156 d DUOX protein specifically localized to the apical surface of epithelial cells.

157 chored proteins (GPI-APs) are located at the apical surface of epithelial cells.

158 motes ENaC biogenesis and trafficking to the apical surface of epithelial cells.

159 immunoglobulins from the basolateral to the apical surface of epithelial cells.

160 This encodes a chloride ion channel on the apical surface of epithelial cells.

161 F5) of gp41 or to cardiolipin (IS4) onto the apical surface of epithelial monolayers prior to inocula

162 ent to HEp-2 cells, is not detectable at the apical surface of HAE cell cultures where RSV enters.

163 t the second ion channel is expressed at the apical surface of hair cells and that it contains the Pi

164 stereociliary bundles that project from the apical surface of hair cells within the cochlea.

165 as immature stereocilia and kinocilia on the apical surface of hair cells.

166 Moreover, since the CSF flows along the apical surface of hindbrain progenitors not expressing W

167 mary receptor; however, AAV2.5T binds to the apical surface of human airway epithelia at higher level

168 ed out by exposing sera and SIVmac251 to the apical surface of human endometrial carcinoma (HEC-1A) c

169 cretory duct begins as buds of chitin at the apical surface of individual secretory cells.

170 tidase (CD73) is expressed abundantly on the apical surface of intestinal epithelial cells (IECs) and

171 ed in the appearance of hCFTR protein at the apical surface of intestinal glands in Cftr-/- hCFTR-G54

172 tein homologues (PfRhs) are expressed at the apical surface of invasive merozoites and have divergent

173 r cluster transmembrane glycoproteins at the apical surface of ionocytes.

174 amics of single MRV virions and ISVPs at the apical surface of live polarized Madin-Darby canine kidn

175 e and the localization of active cSrc at the apical surface of luminal epithelial cells during lactat

176 usly unappreciated actomyosin network at the apical surface of Madin-Darby canine kidney cells.

177 The apical surface of mammalian bladder urothelium is covere

178 IP8, ZIP14 transporters are localized on the apical surface of MDCK-ZIP cells; and 6) like ZIP8, ZIP1

179 of stereociliary bundle (hair bundle) on the apical surface of mechanosensory hair cells (HCs) dictat

180 al expression of biglycan and decorin on the apical surface of MEE, combined with the evidence that t

181 e (55 mmHg for 50 ms) at 26 degrees C to the apical surface of mouse and human nasal epithelial cells

182 nstrate polarized expression of C5aR1 on the apical surface of mouse embryonic neural progenitor cell

183 tethered mucin glycoprotein expressed on the apical surface of mucosal epithelial cells.

184 s in basal body migration and docking to the apical surface of multiciliated cells (MCCs).

185 ts reveal impaired basal body docking to the apical surface of multiciliated cells.

186 Megalin localizes to the apical surface of multiple epithelia, where it participa

187 t that initially locates peripherally at the apical surface of one of the daughter cells.

188 nstrate that these interactions occur at the apical surface of polarized airway tissues.

189 cay-accelerating factor (DAF or CD55) at the apical surface of polarized Caco-2 cells results in rapi

190 t binding of P. aeruginosa aggregates to the apical surface of polarized cells led to the striking fo

191 P-gp in each case is localized on the apical surface of polarized cells.

192 or the first time to visualize events at the apical surface of polarized cells.

193 Microvilli are membrane extensions on the apical surface of polarized epithelia, such as intestina

194 sorting signals that direct proteins to the apical surface of polarized epithelial cells are complex

195 We now show that CD317 is expressed at the apical surface of polarized epithelial cells, where it i

196 and N-formyl-Met-Leu-Phe application to the apical surface of polarized gut epithelial cells resulte

197 ally enter through and are released from the apical surface of polarized human endothelial monolayers

198 MUC1 is efficiently delivered to the apical surface of polarized Madin-Darby canine kidney (M

199 apical proteins take different routes to the apical surface of polarized Madin-Darby canine kidney ce

200 the ability of the bacteria to adhere to the apical surface of polarized T84 epithelial cells was mea

201 l stimulation, such as fluid flow across the apical surface of renal epithelial cells.

202 al infection, reovirus was released from the apical surface of respiratory epithelia and did not disr

203 n to photoreceptor inner segments and to the apical surface of retinal pigment epithelial cells where

204 of the noninhibitory antibody RV6-25 on the apical surface of RV VP6 head domain does not obstruct t

205 ate a contractile myosin II network near the apical surface of supporting cells.

206 tic U937 cells adhered at 4 degrees C to the apical surface of the AECs subjected to ER stress by a m

207 ated myosin light chain were enriched at the apical surface of the airway epithelium during monopodia

208 -derived hydrogen peroxide released from the apical surface of the airway epithelium.

209 bubble suspension was added to buffer at the apical surface of the bladder model before being exposed

210 nsitive hair bundle which protrudes from the apical surface of the cell into a narrow fluid-filled sp

211 ational; the position of basal bodies on the apical surface of the cell.

212 ded to an increase in ENaC expression at the apical surface of the cells and was not present when an

213 (PMCA2), which transports calcium across the apical surface of the cells into milk.

214 s a unique microglial subset residing on the apical surface of the choroid plexus epithelium.

215 evealed that RhoA and AQP2 accumulate at the apical surface of the collecting duct.

216 viruses, respectively, were detected on the apical surface of the culture with different cellular tr

217 -lipoxygenase activity, is secreted from the apical surface of the epithelial barrier and establishes

218 tion step is the detachment of PMNs from the apical surface of the epithelium and their subsequent re

219 The apical surface of the epithelium constitutes the first p

220 m, Upd forms a concentration gradient on the apical surface of the follicular epithelium with a peak

221 ells delaminates from and migrates along the apical surface of the glandular epithelium toward the pr

222 ons that collaborate to build the functional apical surface of the intestinal epithelium in vivo.

223 molecular function of Ezrin in building the apical surface of the intestinal epithelium was not clea

224 rements to develop a mechanical model of the apical surface of the neuroepithelium that incorporates

225 their terminal mitosis, they detach from the apical surface of the neuroepithelium.

226 s demonstrate that traveling waves along the apical surface of the organ of Corti, the reticular lami

227 rase active-site residues are located at the apical surface of the passenger, at the entrance of a la

228 ng potential that approximates the OS to the apical surface of the RPE to facilitate phagocytosis.

229 stereociliary bundles that project from the apical surface of the sensory hair cells.

230 ls in the hair bundles that project from the apical surface of the sensory hair cells.

231 however, about how forces produced near the apical surface of the tissue are transmitted within indi

232 e is positioned away from the nucleus at the apical surface of the ventricular zone of the cerebral c

233 On the apical surface of these renal epithelia, aldosterone inc

234 rylated by S6K1 and abnormally decorates the apical surface of Tsc1-mutant cells with E-cadherin and

235 children and has a selective tropism for the apical surface of well-differentiated human airway epith

236 Computationally 'unrolling' the apical surface of wild-type trachea and the hindgut reve

237 Apical surfaces of cells and their nuclei in monolayers

238 e core PCP protein Vangl2 is detected at the apical surfaces of cells at the blastopore lip, and it f

239 erin-like protein expressed primarily on the apical surfaces of ciliated airway epithelial cells.

240 of aquaporin 1 unexpectedly appeared at the apical surfaces of CLIC4-suppressed RPE cells, together

241 ter heart development, a lumen forms between apical surfaces of contralateral cardioblasts (CBs).

242 Different matrix factors assemble on the apical surfaces of each vulva cell type, with clear dist

243 (LET-4 and EGG-6) that are expressed on the apical surfaces of epidermal cells and some tubular epit

244 n the mouse inner ear, GPSM2 is localized to apical surfaces of hair cells and supporting cells and i

245 membranous yet extracytoplasmic niche on the apical surfaces of host epithelial cells, a process that

246 of juvenile animals localized EsGal1 to the apical surfaces of light-organ epithelia and surrounding

247 d orientation of this polarity such that the apical surfaces of neighboring cells all point toward th

248 short and static MV in confluent cells, the apical surfaces of nonconfluent epithelial cells (ECs) f

249 chondroitin sulfate proteoglycans (CSPGs) on apical surfaces of palatal medial edge epithelial (MEE)

250 When applied to apical surfaces of polarized epithelial cells in monolay

251 Addition of fibronectin to the apical surfaces of polarized T84 cell monolayers augment

252 Apical surfaces of proliferating epithelial sheets have

253 lpha and their localization primarily to the apical surfaces of RPE cells.

254 the modified microvilli projecting from the apical surfaces of the sensory hair cells of the inner e

255 d that Dragon localized predominantly to the apical surfaces of tubular epithelial cells in the thick

256 at are arranged in maze-like patterns on the apical surfaces of zebrafish skin cells.

257 aces of this cluster, but does not reach the apical surface or penetrate into the cluster.

258 FMNL3 and RhoJ are concentrated at the early apical surface, or AMIS, and regulate the formation of r

259 hat must maintain great flexibility at their apical surface; our results suggest that CRIPs function

260 f parasite specific proteins, termed rhoptry apical surface proteins (RASP) that cap the extremity of

261 Here, we identify new roles for two apical surface proteins - Cadherin 99C (Cad99C) and Stra

262 ubule-based directed movement of a subset of apical surface proteins.

263 scopy showed that virions were surrounded by apical surface protrusions and that virus was present in

264 marily expressed in the cytoplasm and at the apical surface rather than in the mitochondria and that

265 Trafficking of NKCC2 to the apical surface regulates NKCC2-mediated NaCl absorption

266 a previously unrecognized driving force for apical surface remodeling and maturation during epitheli

267 Our data suggested that TMPRSS2, an apical surface serine protease, may have a normal role i

268 resulting nonthrombogenic and nonimmunogenic apical surface significantly delays the onset of rejecti

269 oximal tubules, with greater uptake from the apical surface than from the basolateral surface.

270 t, suggesting a protective adaptation of the apical surface that is normally exposed to bile.

271 After transcytosis to the apical surface, the extracellular, ligand-binding portio

272 , harbor two specialized elaborations of the apical surface, the hair bundle and the cuticular plate.

273 al cells with a specialized structure at the apical surface, the mechanosensitive hair bundle.

274 s DLG-1 within adherens junctions and at the apical surface, thereby generating arcade cell polarity.

275 al cells build arrays of microvilli on their apical surface to increase membrane scaffolding capacity

276 nvolves relocalization of the virus from the apical surface to intercellular tight junctions.

277 pylobacter endosome intracellularly from the apical surface to the basolateral surface occurred over

278 Golgi-dependent transport of virus from the apical surface to the extracellular medium was significa

279 e a majority of their HA onto their ciliated apical surfaces to form a heavy chain hyaluronan (HC-HA)

280 emed to be triggered by changes to astrocyte apical-surface topography in response to nanoroughness.

281 Rather, cortical tension at the apical surface translates into planar division orientati

282 rete HIV virions from the basolateral to the apical surface via polymeric Ig receptor (pIgR)-mediated

283 e of TECs was exposed to serum than when the apical surface was exposed.

284 Hexagonality of the apical surface was maintained by the interaction between

285 tachment of M. genitalium to the host cell's apical surface was observed directly and confirmed using

286 Again, beta-ENaC expression at the apical surface was unaltered by either of these manipula

287 he presence of HCO(3)(-), was greater on the apical surface, was reduced on the apical side by ACTZ,

288 y precipitation from basal culture medium or apical surface wash were characterized by nanoparticle t

289 rdinated action of myosin VI and CLCa at the apical surface where these proteins are essential for fi

290 + microglial cells were localized to the RPE apical surface where they participated in the phagocytos

291 basal side (where DNA is synthesized) to the apical surface (where mitosis takes place); such nuclear

292 n from the interendothelial cell area to the apical surface, where JAM-A played a role as a leukocyte

293 n increased the association of sgk1 with the apical surface, whereas methyl-beta-cyclodextrin decreas

294 midbrain neuroepithelium are flat with large apical surfaces, whereas lateral cells are taller and un

295 microvilli and maximize their numbers on the apical surface, which together serve to increase the fun

296 translocation of the cell body away from the apical surface while morphologically rounded up in M pha

297 and that progeny virus is released from the apical surface with little apparent gross cytopathology.

298 ilayers with filters and inoculated on their apical surfaces with 10(6) colony-forming unit bacteria,

299 ion, leading to inappropriate positioning of apical surfaces within the cyst.

300 bly is primed by centrosome migration to the apical surface, yet surprisingly little is known about t