ライフサイエンスコーパス: apoptotic

1 mitochondria, which is instrumental for the apoptotic action of the receptor.

2 sL has been previously implicated in the pro-apoptotic actions of E(2).

3 eceptor UNC5B on T428 residue, promoting its apoptotic activation and dopaminergic neuronal loss.

4 ABA-ergic synaptic markers, possibly via non-apoptotic activation of caspase 3 in neurons located wit

5 n, which is accompanied by YAP reduction and apoptotic activation.

6 yP-1-QU-NPs not only exhibited excellent pro-apoptotic activities but also presented strong inhibitor

7 Furthermore, CBD enhanced the pro-apoptotic activities of JNK1/2 and MAPK p38 signaling ca

8 V-1) latency reactivation depend on the anti-apoptotic activities of latency-associated transcript (L

9 roliferation, induced caspase 3/7 levels and apoptotic activity in PDXC and CCA cell lines.

10 ids as essential and sufficient for the anti-apoptotic activity of AnkG.

11 o investigate whether restoration of the pro-apoptotic activity of FOXO1 may be used as a new promisi

12 anslocation, is more significant for its pro-apoptotic activity than its ability to insert and to for

13 riodontitis-related histological damages and apoptotic activity were also significantly lower in the

14 expression, which is known to inhibit UNC5B apoptotic activity, promotes survival of PyST-expressing

15 nto host cells during infection and has anti-apoptotic activity.

16 The clinical translation of effective pro-apoptotic agents involves drug discovery studies (addres

17 -inducing factor (AIF) and co-localizes with apoptotic AIF.

18 pic signal transducer that promotes both pro-apoptotic and anti-proliferative signaling, and they hig

19 nicated via MSC-secreted cytokines; however, apoptotic and metabolically inactivated MSCs have more r

20 ygen species, as well as lower activation of apoptotic and necroptotic mediators, in 'active-phase' t

21 ore, both HgII and MeHg were found to induce apoptotic and necrotic cell death.

22 nt brain regions, and promotes activation of apoptotic and pyroptotic cell death pathways.

23 ed by suppression of IFN-mediated antiviral, apoptotic, and inflammatory functions, during natural RV

24 al investigations including cytotoxicity and apoptotic assays, and quantitative polymerase chain reac

25 (N-Bak mRNA), leading to suppression of pro-apoptotic BAK1 proteins and allowing neurons to reduce a

26 ion of mitochondrial permeabilization by pro-apoptotic BAX.

27 re in turn, it inhibits up-regulation of pro-apoptotic Bbc3 and Dab2ip.

28 tively, we provide a novel facet of the anti-apoptotic Bcl-2 by demonstrating that its phosphorylatio

29 ent functions of IRF3 and also on Bax, a pro-apoptotic Bcl-2 family protein, through a direct interac

30 Anti-apoptotic Bcl-2 family proteins are overexpressed in a w

31 hijack this mechanism by overexpressing anti-apoptotic BCL-2 family proteins to enforce cellular immo

32 are endogenous factors that can inhibit pro-apoptotic BCL-2 mitochondrial outer membrane translocati

33 ge checkpoint eliminates oocytes via the pro-apoptotic BCL-2 pathway members Puma, Noxa and Bax.

34 a general mechanism of sequestration of pro-apoptotic BCL-2 proteins into fibers by HN to inhibit MO

35 Pro-apoptotic BCL-2 proteins oligomerize at the mitochondria

36 he binding specificity of BH3 domains of pro-apoptotic BCL-2 proteins towards apoptotic suppressors.

37 apoptosis through interactions with the pro-apoptotic BCL-2 proteins.

38 Similar analyses show that anti-apoptotic BCL-x(L) does not form fibers with humanin.

39 of its molecular targets CDK2/5/9, and anti-apoptotic BCL-XL and BCL2 proteins.

40 ntestinal inflammation, the loss of the anti-apoptotic BCL2 family members BCL2 and BCL2L1 has no eff

41 unique cysteine (C55) in the groove of anti-apoptotic BFL-1 to selectively neutralize its oncogenic

42 In response to pro-apoptotic BH3-only protein signaling and pharmacological

43 es so primarily by reducing the level of pro-apoptotic BIM.

44 cription factor SLUG to directly repress pro-apoptotic BMF, limiting drug-induced apoptosis.

45 ndividuals rescued TIM-4 expression, cleared apoptotic bodies and restored a macrophage resolution ph

46 lasma membrane (microvesicles, oncosomes and apoptotic bodies).

47 n macrophages that enables the engulfment of apoptotic bodies, so-called efferocytosis.

48 er" transcripts that originate from engulfed apoptotic bodies, thus obscuring the true transcriptiona

49 a Brazilian isolate being almost exclusively apoptotic but occurring over a prolonged period that is

50 d media into the infarct border zone reduced apoptotic cardiomyocytes > 70% locally.

51 o inefficient efferocytosis, accumulation of apoptotic cardiomyocytes, and a larger myocardial scar.

52 L-265-treatment did reduce entrance into the apoptotic cascade in in vitro and in vivo models of oute

53 hrome c into the cytosol, which triggers the apoptotic cascade.

54 mediate compartment, where DR5 assembles pro-apoptotic caspase 8-activating complexes.

55 ls expressing activated oncogenes experience apoptotic caspase activation, and that Akt1 and dCIZ1 ar

56 ndings demonstrate how Shigella inhibits pro-apoptotic caspase activity, effectively delays coordinat

57 ogrammed cell death when the predominant pro-apoptotic caspase CED-3 is compromised.

58 ter time points than WT mice, but with fewer apoptotic (caspase-3(+) ) neutrophils.

59 es have revealed non-canonical activities of apoptotic caspases involving specific modulation of gene

60 However, how apoptotic caspases regulate GC B cell fate has not been

61 and human macrophages significantly impaired apoptotic cell (AC) engulfment.

62 ins, Yap/Taz also promoted the scavenging of apoptotic cell bodies and necrotic debris by PDA cells.

63 sted the role of inflammation, specifically, apoptotic cell clearance and complement activation in ki

64 Here, we examined the effect of blocking apoptotic cell clearance on anti-tumor immune response.

65 ctions such as blood pressure regulation(1), apoptotic cell clearance(2) and human oocyte development

66 gic signaling, including cancer progression, apoptotic cell clearance, inflammation, blood pressure r

67 ens, such as aflatoxin B(1) (AFB(1)), induce apoptotic cell death and the resulting cell debris stimu

68 reduced proliferation with no difference in apoptotic cell death between control and Ddr1(-/-) anima

69 Depleting ELP proteins promoted apoptotic cell death in an EGFR inhibition-dependent man

70 he unfolded protein response, and ultimately apoptotic cell death in breast and lung cancer cell line

71 The proportion of cortical cells undergoing apoptotic cell death increased, suggesting that cell dea

72 The induction of apoptotic cell death involved loss of mitochondrial oute

73 Regulation of apoptotic cell death is an important component in the co

74 Apoptotic cell death of the treated HeLa and BE(2)-C cel

75 Ferroptosis-an iron-dependent, non-apoptotic cell death process-is involved in various dege

76 As a cell undergoes apoptotic cell death, it experiences changes in morpholo

77 esult of downregulation of M1BP also induces apoptotic cell death, which can be significantly restore

78 ly, mitochondria also have a central role in apoptotic cell death.

79 totic cell death into immunologically silent apoptotic cell death.

80 ilization (MOMP) is a crucial event enabling apoptotic cell death.

81 cribe its biological activity and effects on apoptotic cell death.

82 l or, in the event of chronic damage, induce apoptotic cell death.

83 n of ER homeostasis; that failing, it drives apoptotic cell death.

84 new insights into how mitochondria regulate apoptotic cell death.

85 haperone protein BiP, inducing ER stress and apoptotic cell death.

86 tion in that leads to MESN-subtype-dependent apoptotic cell death.

87 This study investigated whether apoptotic cell engulfment in the murine lung impacts the

88 x morphogenetic event where expulsion of the apoptotic cell is accompanied by rearrangement of its im

89 much has been learnt about the mechanisms of apoptotic cell recognition and uptake, several key areas

90 that is activated in neighbor cells when the apoptotic cell relaxes shortly after injury.

91 Apoptotic cell uptake by lung alveolar macrophages suppr

92 formed after validating the disappearance of apoptotic cell-derived RNA sequences.

93 trated that Tregs were necessary for maximal apoptotic cell-directed enhancement of resolution, and a

94 ghbor cells form at their interface with the apoptotic cell.

95 Apoptotic cells and cell fragments, especially those pro

96 tion of polyreactive B cells that bound both apoptotic cells and commensal bacteria from healthy adul

97 more, 2-HOBA reduces inflammation and plaque apoptotic cells and promotes efferocytosis and features

98 portant for the elimination of pathogens and apoptotic cells and stimulation of the adaptive immune s

99 l for the phagocytosis of infectious agents, apoptotic cells and synapses.

100 g SFK signaling blocks both the expulsion of apoptotic cells and the rosette formation among their ne

101 These data advance the concept that apoptotic cells are not inert cells waiting for removal,

102 data implicate global protein aggregation in apoptotic cells as a mechanism that ensures the overlap

103 Epithelia can eliminate apoptotic cells by apical extrusion.

104 bute to severe asthma, but whether uptake of apoptotic cells by lung phagocytes might dampen house du

105 Clearance of apoptotic cells by macrophages prevents excessive inflam

106 The clearance of apoptotic cells by professional and non-professional pha

107 murine lung, myeloid phagocytes encountering apoptotic cells can deploy alphav integrin-mediated mech

108 ificities that may facilitate the removal of apoptotic cells during development and shape gut microbi

109 Expression of Rho in apoptotic cells enables them to secrete EGFs, which stim

110 Poor clearance of apoptotic cells has been suggested to contribute to seve

111 hibited by peritransplant infusions of donor apoptotic cells in combination with anti-CD40L and rapam

112 ls, fewer dividing cells, and an increase in apoptotic cells in KO mice.

113 Apoptotic cells in PBMCs and tissues increased during pe

114 sion of BCL2 in B cells could largely rescue apoptotic cells in the absence of Fbw7.

115 therosclerotic plaque is the accumulation of apoptotic cells in the necrotic core.

116 tide (termed Apo-15) that selectively stains apoptotic cells in vitro and in vivo in a calcium-indepe

117 How apoptotic cells mediate such diverse effects is not full

118 y, treatment of infected wild-type mice with apoptotic cells significantly increased GM-CSF productio

119 regulates phagocytosis of myelin debris and apoptotic cells that can accumulate and inhibit tissue r

120 stablished in the neighboring epithelium for apoptotic cells to be extruded.

121 Here we show that phagocytosis of apoptotic cells triggers a coordinated transcriptional p

122 Phagocytosis of apoptotic cells via the receptor MerTK is important for

123 However, the percentage of apoptotic cells was similar to conventional embryos.

124 In comparison with saline rats, many apoptotic cells were found in rats injected with 100 mug

125 ange in astrocytes, microglia, and number of apoptotic cells were found.

126 Apoptotic cells were infused into the lungs of mice chal

127 The most important number of apoptotic cells were observed in animals injected with 3

128 After intratracheal instillation, labeled apoptotic cells were observed in most CD11c(+)CD103(+) m

129 ammatory mediators, NF-kappaB expression and apoptotic cells when compared with the Con group, and th

130 lockade of MerTK resulted in accumulation of apoptotic cells within tumors and triggered a type I int

131 , activating mAbs increased the frequency of apoptotic cells without affecting proliferation.

132 that a therapeutic strategy combining donor apoptotic cells, anti-CD40L, and rapamycin effectively i

133 After exposure to apoptotic cells, the F4/80(+) MHCII(LO) subset significa

134 nds with high affinity to PS externalized by apoptotic cells, thereby hindering their interaction wit

135 ylserine (PS) receptors mediate clearance of apoptotic cells-efferocytosis-by recognizing the PS expo

136 clearance of pathogens, immune complex, and apoptotic cells.

137 ropagation also promotes apical extrusion of apoptotic cells.

138 xtracellular particles, such as pathogens or apoptotic cells.

139 or-mediated virus infection and clearance of apoptotic cells.

140 to promote resolution without administering apoptotic cells.

141 ell peritoneal macrophages after exposure to apoptotic cells.

142 encing after co-cultivating macrophages with apoptotic cells.

143 udy the mechanism of suppression elicited by apoptotic cells.

144 red to stimulate the phagocytic clearance of apoptotic cells; however, these therapies can cause off-

145 high doses of BrdU lead to the activation of apoptotic cellular events as evidenced by both terminal

146 The results show a strong apoptotic cellular response, whereby mechanical stimulat

147 TTC7A-deficiency is characterized by apoptotic colitis in milder cases with severe intestinal

148 ting TTC7A signaling in VEOIBD patients with apoptotic colitis.

149 their environment in search of pathogens or apoptotic corpses or debris.

150 hondria-derived signalling downstream of pro-apoptotic cues may also have non-lethal functions.

151 ntracellularly or extracellularly, producing apoptotic cytotoxicity or nonapoptotic effects, respecti

152 an anthracycline, doxorubicin (DOX), induces apoptotic death of cardiomyocytes by activating cyclin-d

153 ration, and thereby, promoting mitochondrial apoptotic death of early osteoclast progenitors.

154 amily of proteins required for mitochondrial apoptotic death.

155 further show that Rbm24 deficiency leads to apoptotic defects in mouse ocular tissue and downregulat

156 gesting that shared intrinsic properties are apoptotic determinants.

157 The apoptotic effect is mediated in large part by the gene i

158 AnkG is one of these anti-apoptotic effector proteins.

159 Apoptotic effects by P. zopfii GT-II were more pronounce

160 t of coregulators and subsequently different apoptotic effects on the antiestrogen-resistant breast c

161 binding site and produces anti-vascular and apoptotic effects.

162 twork formation occurs concurrently with the apoptotic elimination of a third of GABAergic interneuro

163 ents can become immune deficient and develop apoptotic enterocolitis, multiple intestinal atresia, an

164 Mcl1(DeltaIEC) mice might be used to study apoptotic enterocolopathy and inflammatory bowel disease

165 ases 1 and 2, enhanced activation of the pro-apoptotic enzymes caspase-3 and -7 and increased apoptos

166 teine proteases, which also includes the pro-apoptotic enzymes known as caspases.

167 In summary, we identified the anti-apoptotic evolutionary conserved lncRNA Sarrah, which is

168 nd is rescued by genetic blockade of the pro-apoptotic factor BAX.

169 cell cycle regulator (Ccnb1), and increased apoptotic factors (Aifm1 and Bcl2l10) in the colon compa

170 Expression of key apoptotic factors, Dronc (Tc12580), Dredd (Tcn-like, Tc0

171 pmental period hijacks this system to spread apoptotic factors, including complement protein C1q, to

172 c perturbations revealed that the neurogenic/apoptotic fate switch was mediated through cell-cycle re

173 g checkpoint before committing to a terminal apoptotic fate.

174 We evidence that pro-apoptotic fragment generated by caspase cleavage of MET

175 is injected locally to generate immunogenic apoptotic fragments/cells.

176 These results reveal a non-apoptotic function of endothelial caspase-9 which regula

177 nt phosphorylation of FOXO1 restored the pro-apoptotic function of FOXO1 in PCa.

178 Finally, the pro-apoptotic gene Baxwas necessary to generate the dimorphi

179 reased virus replication and inflammatory or apoptotic gene expression.

180 We query the anti-apoptotic genes BCL2L1 and MCL1, and the DNA damage repa

181 evelopmental stages by up-regulating the pro-apoptotic genes reaper and hid The apoptosis induced by

182 Instead of apoptotic genomic DNA, tumor-derived mitochondrial DNA t

183 rious mitochondrial proteins, including anti-apoptotic Hax1.

184 inated infection and midzonal hepatitis with apoptotic hepatocytes and minimal inflammatory reaction.

185 l downregulation and upregulation of the pro-apoptotic histone H2AX but clinically problematic due to

186 odology to characterize viable, necrotic and apoptotic human lymphoma U937 cells.

187 RNA Sarrah (ENSMUST00000140003) that is anti-apoptotic in cardiomyocytes.

188 roup exhibited a significant decrease in the apoptotic index and an increase in the proliferative ind

189 ificantly reduced the fragmentation rate and apoptotic index of blastocysts and increased their total

190 DOX-EDT-IONPs were found to be effective in apoptotic-induced GBM cell death (over 90%) within 48 h

191 overy, we undertook a multiplex screen of 80 apoptotic-inducing agents in paediatric AML pre-clinical

192 inhibition leads to CIC-DUX4 degradation and apoptotic induction.

193 ing peptide sequence (MCP-1 peptide) and the apoptotic KLAKLAK peptide were synthesized.

194 In the injured nerve, macrophages 'eat' apoptotic leukocytes, a process called efferocytosis, an

195 veral approaches, including the detection of apoptotic-like cell death, aflatoxin B(1) (AFB(1)) produ

196 the molecular level and inducing significant apoptotic-like cell death.

197 We show that apoptotic lymphocytes and macrophages release specific m

198 volves primarily genes for components of the apoptotic machinery.

199 ute fraction of cells showed activity of the apoptotic marker caspase-3.

200 showed increased expression of ER stress and apoptotic markers and increased expression of nuclear pr

201 ly following IR, reactive oxygen species and apoptotic markers were significantly decreased and laser

202 sed for cell body diameter, population size, apoptotic markers, and regeneration signaling.

203 ation, migration and increased expression of apoptotic markers.

204 at both heavy metals induce cell death by an apoptotic mechanism.

205 ults and revealing an important role for non-apoptotic mechanisms of cell death during neurodevelopme

206 involve these pathways by enhancing ROS and apoptotic mechanisms.

207 s abrogated in cells lacking Bak/Bax-two pro-apoptotic members of the Bcl-2 family of proteins requir

208 Anti-apoptotic members suppress cell death by deploying a sur

209 capture the critical BH3 alpha-helix of pro-apoptotic members.

210 Here we profiled the apoptotic metabolite secretome and determined its effect

211 Functionally, the apoptotic metabolite secretome induced specific gene pro

212 Mechanistically, the apoptotic metabolite secretome is not simply due to pass

213 Furthermore, a cocktail of apoptotic metabolites reduced disease severity in mouse

214 Using an apoptotic mimicry strategy, the C1-TcCalr association fa

215 , which depends on endosomes accumulating on apoptotic mitochondria.

216 In contrast, the apoptotic modulator drugs SMAC mimetics sensitized B-cel

217 tion by suppressing expression levels of pro-apoptotic molecules.

218 which in turn, leads to the blockage of key apoptotic molecules.

219 macrophages play a critical role in removing apoptotic/necrotic cells in inflammation and injury, a p

220 tellite glia in the DRG involved in clearing apoptotic neurons during development.

221 ittle is known about the mechanisms by which apoptotic neutrophils are cleared in infected tissues du

222 We also recovered more apoptotic neutrophils from RSV-infected cultures (>40%)

223 Apoptotic neutrophils further release epidermal growth f

224 s to all three forms (precursor, mature, and apoptotic) of apoptosis-inducing factor (AIF) and co-loc

225 gions characterized by low T(1) were rich in apoptotic or differentiating neuroblasts.

226 ulated genes were associated with metabolic, apoptotic or DNA repair pathways (including APBA3, PARP1

227 emale intestine, as well as higher number of apoptotic Paneth cells per crypt at 45I-30R (16.4% [7.1-

228 y mutations in genes affecting the extrinsic apoptotic pathway (FAS, FASL, CASP10).

229 L/HCQ co-delivery nanoparticles trigger anti-apoptotic pathway after repetitive intravenous administr

230 insects, the most speciose animal group, the apoptotic pathway has only been fully characterized in D

231 served domain identification to annotate the apoptotic pathway in A. pisum and found low caspase dive

232 Here, we studied the apoptotic pathway in the aphid Acyrthosiphon pisum, an i

233 lective inflammatory milieu within which the apoptotic pathway is a cardinal feature with potential t

234 protein interactions associated with the JNK apoptotic pathway, associations between lung development

235 aspase cascade, which mediates the intrinsic apoptotic pathway.

236 efore oxidizing the lipid and initiating the apoptotic pathway.

237 ressed all the effectors of the PTCH-induced apoptotic pathway.

238 system and eventually activate the intrinsic apoptotic pathway.

239 ignificant enrichment in immune, growth, and apoptotic pathways among the methylation-regulated genes

240 shed light on a novel approach to reactivate apoptotic pathways in advanced PCa and support targeting

241 ression and additionally by preactivated and apoptotic phenotypes.

242 tch to control the accessibility of the anti-apoptotic pocket.

243 Upon exposure to RUX, this apoptotic potential is restored, thereby sensitizing CD8

244 is characterized by decreased mitochondrial apoptotic priming as measured by BH3 profiling, both in

245 ew combinations of stimuli that maximize pro-apoptotic processes.

246 expression of genes that positivity regulate apoptotic processes.

247 them from traditional therapies that rely on apoptotic programmed cell death.

248 ed to a nucleotide-binding adaptor shared by apoptotic protease-activating factor-1, plant resistance

249 HIV also upregulates the anti-apoptotic protein BIRC5, which when blocked promotes dea

250 ications define a critical role for the anti-apoptotic protein MCL-1 as a driver of adaptive survival

251 BAX is a pro-apoptotic protein that transforms from a cytosolic monom

252 tagonistic motif (AVPI) to the inhibitors of apoptotic proteins (IAPs) enters cancer cells and normal

253 ytic' agent, ABT263, which inhibits the anti-apoptotic proteins BCL-2 and BCL-xL and selectively kill

254 teins Bax and Bak and by inhibiting the anti-apoptotic proteins Bcl-XL, Bcl-2 and Mcl-1.

255 osis that correlated with inhibition of anti-apoptotic proteins being sufficient to permeabilize mito

256 dependence on individual or subsets of anti-apoptotic proteins that could be effectively targeted by

257 BCL-2 inhibition drives sequestered pro-apoptotic proteins to MCL-1 and vice versa, explaining w

258 eration and downregulating the expression of apoptotic proteins.

259 ndent kinase inhibitors and upregulating pro-apoptotic proteins.

260 mage checkpoint activation, and an increased apoptotic rate.

261 ion levels resulted in significantly induced apoptotic rates during cisplatin treatment with stronges

262 gand (TRAIL; TNFSF10) receptor (TR) is a pro-apoptotic receptor whose contribution to chronic cholest

263 timmunization; i.e., 3 d after CMH started), apoptotic removal of infiltrated leukocytes during the r

264 istic upregulation of ATF3, and a subsequent apoptotic response in cancer cells.

265 ouble-strand break (DSB) DNA damage, and the apoptotic response is exacerbated by concomitant loss of

266 se to higher levels in sensitive cells, this apoptotic response occurred in p53-defective cells and c

267 the mechanism by which Npro antagonises the apoptotic response will help inform the development of r

268 ally upregulated as part of the shot-induced apoptotic response.

269 cisplatin-induced signalling, DNA-damage and apoptotic responses across a panel of human lung adenoca

270 that MRI-based functional imaging can detect apoptotic responses to MYCN-targeted small-molecule inhi

271 r suppressor mechanisms: the host stress and apoptotic responses.

272 emergence of techniques such as Detection of Apoptotic Retinal Cells and Adaptive Optics confocal Sca

273 We also report apparent non-apoptotic roles for CED-3 in promoting germ cell prolife

274 objective was to determine inflammatory and apoptotic roles of P. zopfii GT-II in cultured mammary e

275 iation in cellular progeny, leading to fetal apoptotic selection that ultimately improves the gamete

276 s nucleic acid fraction originates mainly in apoptotic, senescent and cancerous cells, this approach

277 Both mutations showed pro-apoptotic sensitization by reduced phosphorylation of BA

278 This is then followed by the activation of apoptotic signaling in the CECs, which is known to lead

279 ates pro-oxidative, pro-inflammatory and pro-apoptotic signaling mediated by inducible nitric oxide s

280 iptome analysis revealed that TFEB regulates apoptotic signaling pathways, especially apoptosis inhib

281 though cnidaria are known to contain complex apoptotic signaling pathways, similar to those in verteb

282 dentifies chemical inducers of mitochondrial apoptotic signaling, a mechanism of cell death.

283 hrough the upregulation of p53-dependent pro-apoptotic signaling.

284 d associations with immune response and anti-apoptotic signaling.

285 Apoptotic signalling downstream of MOMP involves cytochr

286 Many cellular stresses are transduced into apoptotic signals through modification or up-regulation

287 reduction of vascularization, and excessive apoptotic staining in unruptured poorly luteinized folli

288 as activation of cell cycle regulators, anti-apoptotic stimuli, metabolic aberrations, and their inte

289 n cell surface modulate their sensitivity to apoptotic stimuli, suggesting expression of Tn/STn may o

290 onic lethality of a mutant defective for the apoptotic suppressor ced-9/Bcl-2 implicating SEP-1 in ex

291 ains of pro-apoptotic BCL-2 proteins towards apoptotic suppressors.

292 ity of these cells to phagocytose myelin and apoptotic T cells.

293 ion of MOMP to levels that fail to reach the apoptotic threshold may paradoxically promote cancer-a p

294 Interestingly, BRB lowered the apoptotic threshold of ABT-199/Venetoclax, a promising B

295 ss, thereby distancing plasma cells from the apoptotic threshold, potentially explaining their high f

296 -3 (BH3) profiling to test the mitochondrial apoptotic threshold.

297 ast two different roles in bone remodelling: apoptotic trigger of the repair protocol, and electro-st

298 A4) are more sensitive to chemical and viral apoptotic triggers, cells lacking MISTRAV or expressing

299 In addition, the phagocytic clearance of apoptotic tumor cells (efferocytosis) enhances the immun

300 ine (PS) molecules exposed on the surface of apoptotic-tumor bodies, such as those induced by chemoth