ライフサイエンスコーパス: appreciably

1 oes not alter the six-helix bundle structure appreciably.

2 adjustments did not change the associations appreciably.

3 enantiomerization, alkylation at C5 slows it appreciably.

4 ation occurring in sewers, do not accumulate appreciably.

5 t did not appear to alter these observations appreciably.

6 r registrations did not change these results appreciably.

7 with either of these changes was not altered appreciably.

8 tes causes the rate of DNA synthesis to slow appreciably.

9 Meanwhile, the refractive index also changes appreciably.

10 esting that major CH4 sources did not change appreciably.

11 layer by 2 nanometers changes the reflection appreciably.

12 hannel responses or neurotransmitter release appreciably.

13 ersons with early diagnosis did not increase appreciably (35% in 2012 vs 37% in 2015; P = .08).

14 rates among eligible patients did not change appreciably (93.7% versus 94.1% from first quarter 2011

15 sly before the motors can load the substrate appreciably (a second regime of frictional slippage).

16 Furthermore transgenic SYT-alpha does not appreciably accumulate in nonpeptidergic neurons in vivo

17 s that allow the solute molecules to diffuse appreciably across the cross section of the flow before

18 ults reveal that the S3a helix does not move appreciably across the membrane in association with gati

19 ase IIIalpha-XRCC1, which completes BER, was appreciably active only at concentrations that led to nu

20 nging the size distribution of hosts did not appreciably affect aggregation.

21 ion by expression in different hosts did not appreciably affect antigenicity or overall immunogenicit

22 of the tumor, because injection site did not appreciably affect CD8 T cell priming in tumor-free mice

23 d, variations in cosmic ray intensity do not appreciably affect climate through nucleation in the pre

24 se wild-type male, the Y chromosome does not appreciably affect dosage compensation.

25 Loss of gene function does not appreciably affect endogenous gene expression.

26 r STT3B-OST activity, by themselves, did not appreciably affect HSV-1 function (plaque-forming units,

27 IL-22 antibody did not appreciably affect IRI but increased IL-22R1 transcripti

28 The near absence of rNMPs did not, however, appreciably affect mtDNA copy number or the levels of mt

29 vival of SMA mice by replacement and did not appreciably affect survival when used to deplete SMN.

30 ions of the FAMEs and n-alkanes, but did not appreciably affect the aromatic compounds.

31 Rab5, however, did not appreciably affect the PM localization or function of th

32 ctivation-induced cytidine deaminase did not appreciably affect the survival of these animals, sugges

33 ures traditionally used for HA and FA do not appreciably affect their binding characteristics.

34 Although activation of the IGF-IR did not appreciably affect their growth, it did promote migratio

35 1 Type-1 receptors (0-4 microg, s.c.) didn't appreciably affect these behaviors.

36 ing of acid-base equivalents, they could not appreciably affect transport rates of NBCe1 or other tra

37 This process is not appreciably affected by a suppression of autophagy, prev

38 BOADICEA and IBIS predictive scores were not appreciably affected by limiting input data to family hi

39 d (iii) labeling of intact organisms was not appreciably affected by proteinase K (PK) treatment.

40 Neither compound appreciably affected STAT1 or STAT5 DNA-binding activiti

41 other cytokinin signaling elements were not appreciably affected.

42 replication in primary rhCD4 T cells without appreciably affecting antigenicity or antibody-mediated

43 ingle predicted gD TEV protease site without appreciably affecting its replication characteristics.

44 nductivity relative to pristine PbSe without appreciably affecting the power factor.

45 fects are localized to the A1 domain without appreciably affecting the structure and dynamics of othe

46 nd caused regression of existing NV, without appreciably affecting vasculogenesis or retinal revascul

47 HRs did not change appreciably after further adjustment for lipid, inflamma

48 ugh most histone modifications do not change appreciably after genotoxic stress, H3K9Ac and H3K56Ac a

49 s and surface characteristics did not change appreciably after treatments at pH 3 for 2h, pH 6.5 for

50 peptides that lacked the Nt17 domain did not appreciably aggregate on or insert into lipid membranes.

51 genesis by the carbon monoxide poisoning was appreciably alleviated by early treatment of hyperbaric

52 e only in cancer registries does not seem to appreciably alter measures of performance.

53 Previous USPSTF recommendations did not appreciably alter prostate cancer screening.

54 Usp14 inhibition did not appreciably alter protein synthesis and only partially d

55 val and Tweedie trim-and-fill method did not appreciably alter results.

56 ocardial infarction during follow-up did not appreciably alter results.

57 ight and childhood lifestyle factors did not appreciably alter results.

58 Coexpression of MCPyV tLT did not appreciably alter the phenotype driven by either sT or s

59 icity, and time since seroconversion did not appreciably alter the results.

60 otype, and failed ARHGAP6 expression did not appreciably alter the severity of enamel defects when AM

61 tingly, mutation of the IRM sequence did not appreciably alter the subcellular trafficking of IRAP.

62 negative on skin prick testing, and were not appreciably altered by the effect modifiers, apart from

63 d [Ca2+]SR, suggesting that SR volume is not appreciably altered in HF.

64 However, plasma S1P levels were not appreciably altered in mice that were thrombocytopenic,

65 No potential mediators appreciably altered the magnitude or significance of sle

66 tal conditions, axonal microtubules were not appreciably altered with regard to their sensitivity to

67 ted traits per unit inbreeding, did not vary appreciably among populations or with time.

68 The pattern of mutation burden varies appreciably among racial groups.

69 irtual Reality (iVR) technology has improved appreciably and affords a relatively straightforward met

70 hern and southeastern basin do not desiccate appreciably and that extensive areas experience an incre

71 The procedure times did not change appreciably as compared with historical controls.

72 ear, semiflexible polymer chains that do not appreciably associate with one another under the conditi

73 hain n-3 PUFAs were neither consistently nor appreciably associated with change in body weight or wai

74 tion or intensity of menstrual flow were not appreciably associated with fecundability.

75 ted, polyunsaturated, and trans-fat were not appreciably associated with UL incidence.

76 takes of total fat and fat subtypes were not appreciably associated with UL risk overall, although st

77 the amplitude of global Ca2+ waves increased appreciably at lower temperatures, probably as a result

78 y photolysis, whereas chlorination could not appreciably attenuate the observed GR activity.

79 ysteine supplementation in vitro and in vivo appreciably augmented vaccine responses.

80 our more flexible model often fits the data appreciably better than the single inverse gamma distrib

81 Variants of the rule were not appreciably better.

82 ed by various Candida species did not change appreciably between 2004 and 2007, and the rate of antif

83 ation of oncologists' services will increase appreciably between 2005 and 2020; this will be driven p

84 contrast, serotype diversity did not differ appreciably between colonizing and AC-causing pneumococc

85 ms between these compartments did not differ appreciably between DF(-) and DF(+) stools.

86 of functional IP(3)R within clusters differ appreciably between different puff sites, and we investi

87 (ie, frequency and location) did not differ appreciably between methods.

88 f IPD caused by specific NVTs did not differ appreciably between risk groups in the postvaccination p

89 d, if control strategies could reduce dengue appreciably, billions of dollars could be saved globally

90 s UPR-regulated transcription factor did not appreciably bind the ifnb1 promoter.

91 For instance, JNK1 and JNK2 do not appreciably bind to any D-sites other than their cognate

92 n DKK-1 with picomolar affinities yet do not appreciably bind to DKK2 or DKK4.

93 but those who did hold a growth mindset were appreciably buffered against the deleterious effects of

94 advanced prostate cancer risk did not differ appreciably by age, family history of prostate cancer, s

95 In general, sensitivity did not change appreciably by endemic infection status, even after adju

96 urrence of a recurrent MI and did not differ appreciably by HF type.

97 of gate interconversion will not be affected appreciably by large viscogens, such as macromolecules f

98 Results did not vary appreciably by past or current use, days per week of use

99 ents with cystic fibrosis (CF) does not vary appreciably by socioeconomic status (SES), disparities w

100 This association did not differ appreciably by stage, menopausal status, body mass index

101 .60 (range, 0.55-0.68), which did not differ appreciably by study design, sample size, participants'

102 t that cargo transport may not be influenced appreciably by the combined action of multiple kinesins.

103 We show that the fraction of traits altered appreciably by the deletion of a gene is minute for most

104 This risk did not vary appreciably by tumor stage, size, hormone receptor expre

105 after 28 weeks of therapy, did not otherwise appreciably change ALP and overt proof-of-concept was no

106 genetic factors in co-twin analyses did not appreciably change estimates.

107 Analytic adjustments did not appreciably change IDU prevalence estimates due to subop

108 diabetes status and other covariates did not appreciably change the associations.

109 Further adjustment for weight change did not appreciably change the interactions for fasting insulin

110 In contrast, low levels of ICP0 did not appreciably change the levels of histones on the viral g

111 sults in faster radiative decay but does not appreciably change the overall emission intensity becaus

112 results obtained during the ICU stay did not appreciably change the predictive accuracy of this test

113 he substrate within the active site does not appreciably change upon Schiff base formation.

114 Findings were not appreciably changed after accounting for competing death

115 PDUFA deadlines have appreciably changed the approval decisions of the FDA.

116 Here, we show that Y. pestis does not appreciably cleave A2AP in a Pla-dependent manner in the

117 y, which demonstrate these cyclophanes to be appreciably comparable to the diketophosphanyl systems c

118 itions where the resulting aggregates do not appreciably condense.

119 ied prunes and peanuts were the only samples appreciably contaminated, 14.7-124.3 and 10.0-42.9mug/kg

120 -isotope labeling and show that PDH does not appreciably contribute to acetyl-CoA synthesis, tricarbo

121 ate that differences between individual gels appreciably contribute to CA variation.

122 arasite, it is unclear if glucose metabolism appreciably contributes to the acetyl-CoA pools required

123 nded well to tones; neighboring neurons were appreciably cotuned, and preferred frequencies adhered t

124 how that internal and global motions are not appreciably coupled in this single-domain protein.

125 We also found that a candidate drug did not appreciably cross the mutant BBB.

126 support NC-like structure formation, did not appreciably decrease luciferase expression, indicating t

127 nterfering ion of high concentration did not appreciably deplete, the second electrolysis step may be

128 s the receptor with high affinity and can be appreciably depleted by receptor binding, then negative

129 RFC does not appreciably destabilize the closed state of PCNA.

130 M87 is widely expressed, while M1 is appreciably detected only in adult spinal cord.

131 The results did not appreciably differ by the type or dose of LES consumed,

132 In particular, the effective dose is not appreciably different from those obtained with other hyp

133 the points where two SWNTs cross do not show appreciably different HET kinetics relative to the sidew

134 The electrode double layer capacity is not appreciably diminished by the adsorbed ferrocenated nano

135 aximum gating charge (Q(max)) (33%), without appreciably diminishing the physical number of channels

136 Thermal processing did not appreciably disrupt tomato cells, and therefore only led

137 ss of the Drosophila homolog CG1826 (dBTBD9) appreciably disrupts sleep with concomitant increases in

138 hotocycle while a mutation of Met93 does not appreciably disturb the formation of the light-excited s

139 but it is well accepted that pathogenesis is appreciably driven by a hyperactive immune response.

140 stiff springs (so that they did not shorten appreciably during the simulations), force relaxed with

141 e of HCO3 (-) into the carboxysome would not appreciably enhance energetic efficiency.

142 nomolar and micromolar Ca(2+) concentration, appreciably enhanced actin filament severing caused by H

143 riggered large scale endocytosis and did not appreciably escape the endosomal compartments in the 1-h

144 an atom of a heavy element in a compound can appreciably, even drastically, alter the NMR shifts of t

145 he concentration of trans-stilbene, [t-Stb], appreciably exceeds the concentration of adventitious wa

146 estimates for short-term pollutant averages appreciably, except for time-activity patterns, which st

147 lasmically truncated DC-SIGN in microdomains appreciably exchanged with like molecules in other micro

148 In concert, these studies have appreciably expanded our understanding of the compositio

149 y maturation were normal, and PIK3IP1 is not appreciably expressed in germinal center B cells.

150 yranosides as triols, axial 4-O-acylation is appreciably faster than O-acylation of the primary 6-hyd

151 results show that the ABLM + DNA reaction is appreciably faster, has a different kinetic isotope effe

152 predicted that dendritic filtering does not appreciably favor one synaptic class over another.

153 ities whose way of life may not have changed appreciably for centuries.

154 ted analyses, median spending did not differ appreciably for participants who experienced negative co

155 1) at 30 through 31 weeks but did not change appreciably for those born at less than 25 weeks.

156 ry structure of the RIIbeta tetramer differs appreciably from our model of the RIalpha tetramer, conf

157 if disease prevalence in the sample differs appreciably from the background population prevalence.

158 ific El Nino events on global climate differ appreciably from those associated with eastern Pacific E

159 ng its very strong LHb inputs, do not differ appreciably from those of the ventral tegmental area (VT

160 Uptake was appreciably higher for rural compared with urban dweller

161 smoking, risk for nonaffective psychosis is appreciably higher in the smoking member.

162 normous number of patients for tuberculosis, appreciably higher than has been previously recognised.

163 and Wales among people aged 25-50 years were appreciably higher than in the comparator group.

164 itions per 100 survivors; these numbers were appreciably higher than those in the control cohort (227

165 f Health Roadmap Initiative, aims to improve appreciably how PROs are selected and assessed in clinic

166 nd occupation did not influence the patterns appreciably; however, stronger gradients for adiposity w

167 y substrates with P1-Arg, -Lys, or -Met were appreciably hydrolyzed.

168 an active site NPP4 mutant, neither of which appreciably hydrolyzes Ap3A, have no effect on platelet

169 to different k(op) values or, at least, not appreciably if the k(op) values are different.

170 Infused cells did not appreciably impact acute or chronic viral replication.

171 n and lipid composition of exosomes does not appreciably impact exosomes' rate of clearance and biodi

172 imulus, and suggests that amiloride does not appreciably impact responses to nonsodium salts at the b

173 the main (Y181 only) HIV-1 lineages did not appreciably impact RT activity or function.

174 postinfection lung bacterial burden did not appreciably impact the kinetics of competence induction.

175 ponses in subject 00015, vaccination did not appreciably impair his ability to contain viremia at lev

176 om temperature-sensitive hsp70-2 mutants was appreciably impaired.

177 alysis of BNP and C-reactive protein did not appreciably improve risk prediction over the model that

178 Their outlook has not appreciably improved in decades.

179 ased in 34 patients on CR and did not change appreciably in 36 on SD.

180 or GrpE co-chaperone interaction is affected appreciably in all of the mutations except for R56A.

181 id ART initiation among 10-14-year-olds rose appreciably in countries with earlier treatment expansio

182 id ART initiation among 10-14-year-olds rose appreciably in countries with earlier treatment expansio

183 ersons younger than 40 years of age but rose appreciably in frequency with age.

184 T cells in the epidermis that did not change appreciably in numbers following IL-23 injection.

185 are key design features [4, 6, 8], they vary appreciably in overall shape and hook dimensions.

186 4-electron LCuH hexamers does not dissociate appreciably in solution, although their hydride ligands

187 stability of TnaC-tRNA(2)(Pro) was increased appreciably in strains deficient in RRF and RF3 or defic

188 n the dyadic cleft during each beat, but not appreciably in the cytosol.

189 The hindlimb of theropod dinosaurs changed appreciably in the lineage leading to extant birds, beco

190 is stable for weeks with ability to perform appreciably in wide pH (3-6) and temperature range (25-6

191 dy, the sputter rate was found to not change appreciably in x, y, or z, and the cellular material was

192 tion, the flagellin-expressing virus did not appreciably increase DC surface expression of the costim

193 instead favoring cooperative behaviors that appreciably increase the carrying capacity of the popula

194 n the presence of fructose or xylose did not appreciably increase their production.

195 7 degrees C min(-1)) to 30 degrees C did not appreciably increase turbidity or droplet diameter (d ap

196 ures below the PIT followed by rapid cooling appreciably increased droplet size and turbidity (thermo

197 these study design elements has overall not appreciably increased over the past decade, except in pr

198 nked coumarin derivative (22) that exhibited appreciably increased potency (GI50 5.4 +/- 0.1 nM), but

199 tatus in Europeans may be associated with an appreciably increased risk of HCC development.

200 lene tetrahydrofolate reductase gene (MTHFR) appreciably increases homocysteine levels, so "Mendelian

201 HPCAL1 did not appreciably influence the ability of WT PHOX2B to transa

202 3) Clinical outcomes appear most appreciably influenced by patient behaviors and surgical

203 refutes the hypothesis that COP seep methane appreciably influences carbon dioxide dynamics.

204 .9 microM, of which 7 of 9 molecules did not appreciably inhibit FV membrane binding and were thus sp

205 hat the local protein environment can either appreciably inhibit or accelerate the reaction of single

206 ermediate to the hafnocene oxamidide was not appreciably inhibited by carbon monoxide and support a p

207 Knockdown of FAK appreciably inhibited class I-mediated phosphorylation o

208 stic studies led us to discover that FTY-720 appreciably inhibited nuclear factor of activated T-cell

209 e studies to demonstrate that mVP40 does not appreciably insert into the hydrocarbon region of anioni

210 In both cases, HSP60 does not appreciably interact with Bax.

211 n ten centimetres, whose orbits do not decay appreciably inward over 4.5 billion years, contribute at

212 ty rate of human H5N1 influenza infection is appreciably less than the figure of approximately 60% th

213 ion of heat dissipation, while GBs of MoS(2) appreciably localize heating in the device.

214 products upon light irradiation, tend to be appreciably longer in MWCNT/8 than in SWCNT/8.

215 odies (5.1-15uM); the 24 others examined are appreciably lower (most <= 2.6uM).

216 The ratio of (240)Pu/(239)Pu was appreciably lower for sediment samples compared to the a

217 than 150 degrees with organic liquids having appreciably lower surface tensions than that of water-ar

218 emperature swings, and regeneration energies appreciably lower than achievable with state-of-the-art

219 say complexity and the resolution thereof is appreciably lower than the reconstructions being assesse

220 entative therapies to CABG patients does not appreciably lower the risk of VTE.

221 inesins, multiple myosin complexes move with appreciably lower velocities than a single-myosin molecu

222 The observed associations were not appreciably modified by region, baseline age or the leng

223 The associations were largely not appreciably modified by several breast cancer risk facto

224 between serum UA and the primary outcome was appreciably modified by sex (P-interaction = 0.007).

225 en LComega3PUFAs and incident asthma was not appreciably modified by sex, race, BMI, smoking status,

226 and Dkk4 transgenic mice showed a subtly but appreciably modified claw phenotype.

227 by the nanostructured surface, which in turn appreciably modifies gamma(SL).

228 in hepatocytes and complete PACE4 KO did not appreciably modify plasma HDL levels or EL activity.

229 status, and selenium supplementation did not appreciably modify these results.

230 ommunity are at risk for HF (Stages A or B), appreciably more compared with previous reports in young

231 isostructural system (P3(Si)) is shown to be appreciably more selective for hydrogen evolution.

232 Moreover, the CI chemosensor was appreciably more sensitive to FU than to their common in

233 -dimethylformamide, in which SBU adducts are appreciably more stable and compact.

234 respiration rates within the plume were not appreciably more than 1 micromolar oxygen per day.

235 paths in the in vitro motility assay became appreciably more winding in both the presence and absenc

236 module pair CCPs 12-13 does not bind heparin appreciably, notwithstanding previous suggestions to the

237 bound oxide molecules that do not dissociate appreciably on energetic ion bombardment.

238 nts lacking both pathways are unable to grow appreciably on ethylamine.

239 nverts to a conventional partial agonist and appreciably opens the channel in the absence of a positi

240 iagnosis, rates of survival have not changed appreciably over 30 years.

241 f glaucoma patients nationwide will increase appreciably over the coming years reflecting the increas

242 the mass of emerging insects did not change appreciably over the mining gradient.

243 Wing-spot patterns had not changed appreciably over time on three of the islands (two large

244 tion, the rate of initial follow-up improved appreciably over time.

245 unctions are such that the L(o) state is not appreciably populated in the pure phospholipid, at any t

246 ng that basal levels of urate in mice do not appreciably protect against oxidative damage and neuroto

247 s, can function to control infection without appreciably recognizing mature virions.

248 dual signal transduction inhibitors does not appreciably reduce tumor invasion, because these pathway

249 However, a glycan attached at position 476 appreciably reduced both VWF binding and proteolysis.

250 the inlet of a charged solid-state nanopore, appreciably reducing the charge density of the NP as it

251 se R (PKR), MTAP44, and particularly viperin appreciably restricted BUNV replication.

252 is acknowledged that donor cells are neither appreciably retained nor meaningfully contribute to tiss

253 The biosensors were appreciably selective with respect to the nucleobase mis

254 SA) and Mycobacterium tuberculosis (Mtb) are appreciably sensitive to changes in the intracellular ox

255 Critical slowing down starts growing appreciably several years before the Disneyland outbreak

256 ses and that cochlear amplification does not appreciably sharpen frequency tuning for cochlear region

257 larly, the time course of the signal did not appreciably shift in time or shape.

258 particle concentrations have been declining appreciably since 2010/11 due to the use of diesel parti

259 he cognitive model of depression has evolved appreciably since its first formulation over 40 years ag

260 ity within the aged alpha-pinene SOA remains appreciably slow even at 80% RH, resulting in hindered p

261 Cofactor formation was also appreciably slower than the rates reported for other enz

262 While Gluc is already appreciably small for a luciferase, a reduction in size

263 e predict MRJ states with densities that are appreciably smaller than is conventionally thought to be

264 When the proteins are appreciably smaller than the nanopore, an opposite recti

265 cal volatilization, and contaminants did not appreciably sorb into cross-linked polyethylene (PEX) pi

266 dine, s(2)U(34), and pseudouridine, Psi(39), appreciably stabilized the interaction of the anticodon

267 It is, however, appreciably stabilized upon binding to integrins.

268 aster formation, which however did not alter appreciably the rate of cell proliferation.

269 d "negative placebo effects," can contribute appreciably to a variety of medical symptoms and adverse

270 etic variation among populations contributes appreciably to differences in gene expression phenotypes

271 lter has been hypothesized to not contribute appreciably to hydrophobic organic compound (HOC) partit

272 her treatment-related toxicities contributed appreciably to overall mortality.

273 iac fibroblasts did not appear to contribute appreciably to regeneration of cardiac endothelium.

274 rodomains near the membrane that contributed appreciably to resting Ca(2+) in astrocytes.

275 tander T-cell activation does not contribute appreciably to the CD8(+) CD44(hi) pool.

276 d" FVIII products are unlikely to contribute appreciably to the inhibitor incidence in African Americ

277 , suggests that MSO spikes do not contribute appreciably to the neurophonic.

278 l other, larger inversions do not contribute appreciably to the phenotype.

279 ator of cardiovascular adaptation contribute appreciably to the reduced risk of preeclampsia in subse

280 conditions under which vibrations contribute appreciably to the stresses in the follicle remain uncle

281 h cell proliferation is likely to contribute appreciably to the total energy budget of the embryo.

282 Furthermore, although ANS did not bind appreciably to the WT holoenzyme, incubation of metal-de

283 ng carcinoma cells (A549), but they were not appreciably toxic toward endothelial cells (HUVECs).

284 1A to synthesize ubiquitin chains, it is not appreciably ubiquitinated.

285 Surface water chemistry did not change appreciably until several kilometers into the urban envi

286 sting membrane potentials, and only activate appreciably upon depolarization.

287 alococcoides and vcrA concentrations did not appreciably vary.

288 Appreciably, we provide insights into the distinct micro

289 y in determining UCEIS scores did not change appreciably when a video was presented with clinical det

290 to the potential of mean force do not change appreciably when the molecules are stretched in explicit

291 anging distance, the protein does not adsorb appreciably, while a decreasing peak area with increasin

292 ed cells without diluting the captured cells appreciably, while maintaining viability (the viability

293 Dlp protein core does not, however, interact appreciably with either Hh or an Hh:Ihog complex.

294 high loads, motor switching rates increased appreciably with load.

295 The efficiency of alkylation varied appreciably with substituents in the carboxylic acids.

296 the AUCs for type 2 diabetes did not improve appreciably with the addition of genetic markers into co

297 binary, in that only one cell type interacts appreciably with the boundary.

298 e find that the indirect bandgap size varies appreciably with the stacking configuration: it shows th

299 acts with the single strand template but not appreciably with the template strand of the DNA stem gre

300 n of the study, the nitrite signal decreased appreciably with time.