ライフサイエンスコーパス: appreciate

1 alizability of results than most researchers appreciate.

2 ptor signalling is more common than hitherto appreciated.

3 tity and importance are just beginning to be appreciated.

4 sregulation is more pervasive than currently appreciated.

5 odeling at the division site than previously appreciated.

6 zes are considerably greater than previously appreciated.

7 pose a more serious threat than is currently appreciated.

8 act on targeted therapies has not been fully appreciated.

9 cy in the retinal color code than previously appreciated.

10 rgent biogeographic lineages than previously appreciated.

11 that explain why time poverty is often under appreciated.

12 ion in cultural and social evolution is well appreciated.

13 ctors that link these processes remain under-appreciated.

14 n, but its broader role in cognition is less appreciated.

15 ly equivalent cells is becoming increasingly appreciated.

16 re of hydroperoxide products than previously appreciated.

17 l tumorigenesis that has not been previously appreciated.

18 re extensive and predictable than previously appreciated.

19 of nerves within tumor tissues has long been appreciated.

20 a much broader tumor spectrum than currently appreciated.

21 te more to target recognition than is widely appreciated.

22 inding site of MraY that were not previously appreciated.

23 anism utilized by Nature which has yet to be appreciated.

24 activity in malignant cells than previously appreciated.

25 ers on interpreting data is not always fully appreciated.

26 rected reward-seeking behavior has been long appreciated.

27 ents and their enzymatic degradation is less appreciated.

28 gation remains somewhat overlooked and under-appreciated.

29 nching morphogenesis earlier than previously appreciated.

30 nsively, their chaotic behavior has not been appreciated.

31 he host response to infections has long been appreciated.

32 l placentation has remained remarkably under-appreciated.

33 in other areas of biology are not as widely appreciated.

34 tion were more heterogeneous than previously appreciated.

35 ects of heat stress responses not previously appreciated.

36 of A1 is more heterogeneous than previously appreciated.

37 Coinfections are more common than is often appreciated.

38 ntigen carriers inducing immune tolerance is appreciated.

39 on within natural populations than currently appreciated.

40 metabolic processes, are being increasingly appreciated.

41 more diverse and complex than was previously appreciated.

42 linical and genetic spectrums than currently appreciated.

43 er breakdown of oral tolerance than hitherto appreciated.

44 owever, such rules are less common and under-appreciated.

45 cet of these viruses that was not previously appreciated.

46 ancer are more prominent than was previously appreciated.

47 humans and Neanderthals than was previously appreciated.

48 innate immune response during infection was appreciated.

49 pathogen interactions is only recently being appreciated.

50 fore theropod flight evolved than previously appreciated.

51 augmentation approaches than was previously appreciated.

52 s in greater detail than has previously been appreciated.

53 ransient motions being larger than generally appreciated.

54 icated role in Shh signaling than previously appreciated.

55 r more ancient and conserved than previously appreciated.

56 rger role in health outcomes than previously appreciated.

57 nges of individual nucleotides-remains under-appreciated.

58 gulatory role in translation than previously appreciated.

59 m effects of early thymectomy are just being appreciated.

60 fficacy may be more widespread than has been appreciated.

61 higher risk of osteoporosis than previously appreciated.

62 increased attention, but little is known or appreciated about the effect of climate change on chroni

63 While well appreciated, almost all analyses of GWAS data consider r

64 outcome of a glycosylation reaction is well appreciated and documented.

65 ammadelta T cell development than previously appreciated and represents a critical checkpoint in the

66 migrants may be more common than previously appreciated and suggest the delineation of a hitherto po

67 l and exon-level coverage can be immediately appreciated and taken into consideration for further med

68 tes by HDAC6 is more complex than previously appreciated and that domains outside the tandem catalyti

69 n tumor progression than has been previously appreciated and that germline variation holds substantia

70 significantly more variable than previously appreciated and that they can impact species-specific T-

71 ons are more easily achieved than previously appreciated and that they occurred in past climate condi

72 ounding this phenomenon remains incompletely appreciated and understood, especially as applied to cli

73 ering may be more significant than currently appreciated, and a fuller understanding is needed for pr

74 heterogeneity in virus capsids may be under-appreciated, and also points to a nontraditional strateg

75 cause of heart failure (HF) than previously appreciated, and novel treatments for amyloidosis are em

76 be more prevalent in the ARC than previously appreciated, and play predominantly an anorectic role in

77 esenchymal cells within tumors has long been appreciated, and recent studies suggest molecular and fu

78 s significantly more diverse than originally appreciated, and that MbnH is most closely related to th

79 s of assay systems to measure ROS need to be appreciated, and the development of novel techniques/rea

80 ds during microbial keratitis is not readily appreciated, and treatment options do not address the co

81 However, less appreciated are the downsides of this endosymbiosis.

82 The habenula complex is appreciated as a critical regulator of motivated and pat

83 Lactate is now appreciated as a crucial energy source, major gluconeoge

84 Colorectal cancer (CRC) is increasingly appreciated as a heterogeneous disease, with factors suc

85 renin-angiotensin system (RAS) has long been appreciated as a major regulator of blood pressure, but

86 mplex environment within cells has long been appreciated as a major regulator of enzymatic activities

87 on of epigenetic information is increasingly appreciated as a potential driving mechanism in both dev

88 oxia-inducible transcription factor HIF-1 is appreciated as a promising target for cancer therapy.

89 In addition, glia are now increasingly appreciated as active regulators of numerous physiologic

90 tumor microenvironment (TME) is increasingly appreciated as an important determinant of cancer outcom

91 respiratory microbiota is increasingly being appreciated as an important mediator in the susceptibili

92 ribonucleoprotein (RNP) granules has become appreciated as an important regulator of RNA metabolism.

93 RBPs are increasingly appreciated as being essential for normal hematopoiesis,

94 phenotypic impact of rare variants is under-appreciated as gene function is normally studied in the

95 omain containing 5 (DEPDC5) are increasingly appreciated as one of the most common causes of inherite

96 the Chilean hazelnut (Gevuina avellana) are appreciated as snacks.

97 an earlier processing stage than previously appreciated, as even so-called monocular neurons in V1's

98 rphism in AMP genes than has previously been appreciated, as well as adaptive loss of AMP activity.

99 ell death in brain development has long been appreciated, but many basic questions remain, such as wh

100 compartmentation of cAMP signaling has been appreciated, but outside of dendritic synaptic regulatio

101 Aberrant metabolism of cancer cells is well appreciated, but the identification of cancer subsets wi

102 neities in the postischemic VT substrate not appreciated by any single modality alone.

103 Heather honey is highly appreciated by consumers for its sensorial profile, whic

104 Saffron is appreciated by its colour, taste, and aroma.

105 innate immune clearance in ways that are not appreciated by standard antibiotic testing and that meri

106 osition and quality of CGT, commodity widely appreciated by the consumers.

107 he organoleptic evaluation, F1 was also most appreciated by the tasting panel.

108 rimary mitochondrial dysfunction is an under-appreciated cause of cardiomyopathy, especially when car

109 suggest the delineation of a hitherto poorly-appreciated "Central Asian Flyway", which must funnel hu

110 With regards to the safety of this appreciated commodity, the control on the entire product

111 Biased signaling and other recently appreciated complexities of GPCR signaling thus appear t

112 essing and localization are previously under-appreciated contributors to the rapid evolution of funct

113 LV genome are more extensive than previously appreciated, covering 100% of the genome; contributions

114 ace a tremendous challenge in that we should appreciate differences in students' instructional needs

115 raction appears to be greater than generally appreciated, differs between patients with and without a

116 disappointing outcome, including failure to appreciate disease heterogeneity, inappropriate use of r

117 etween core ASD and comorbid symptoms-a less appreciated domain of heterogeneity in ASD.

118 Nevertheless, this fruit is very appreciated due to its sweet pulp (high sucrose content,

119 Nuts are highly appreciated due to their nutritional relevance and flavo

120 Genomes of the highly appreciated edible desert truffles Terfezia claveryi Cha

121 This paper discusses the less-appreciated fact that enrollment is often based on other

122 An under-appreciated factor in managing the water-food-energy (WF

123 Layering has been a long-appreciated feature of higher order mammalian brain stru

124 de in the reticular interstitium, a recently appreciated fluid-filled space within and between tissue

125 Control bread (20 g/kg salt) was the most appreciated, followed (greater than80% consumers) by bre

126 proteins in RNA virus replication have been appreciated for a decade, the equally important function

127 It has been appreciated for decades that optimal levels of dopamine

128 The complexity of heredity has been appreciated for decades: Many traits are controlled not

129 aba (Vell.) Berg) is a Brazilian berry, very appreciated for in natura consumption.

130 isia esculenta tree, is largely consumed and appreciated for its bittersweet taste; however, detailed

131 cha inchi (Plukenetia volubilis) oil (SI) is appreciated for its nutritional and sensorial characteri

132 rotenoids and antioxidant compounds, is well appreciated for its organoleptic characteristics.

133 myloid precursor protein (APP) has long been appreciated for its role in Alzheimer's disease (AD) pat

134 e Silhavy group, Mla has become increasingly appreciated for its role in bacterial cell envelope phys

135 for biosynthetic pathways, metabolism is now appreciated for its role in providing metabolites, small

136 It has been appreciated for many years that there is a strong associ

137 tabolites produced by soil bacteria has been appreciated for over a century, and advances in chemical

138 ity notes at the sensory analyses, and being appreciated for their body balance, less acidity, and fl

139 ceptor-G protein coupling, arrestins are now appreciated for their expanding repertoire of dynamic pr

140 both protein families are membrane scaffolds appreciated for their role in exosome formation, composi

141 Metabolites are increasingly appreciated for their roles as signaling molecules.

142 ultheria phillyreifolia and G. poeppigii are appreciated for their sweet taste and aroma.

143 s been realized by various means, applicably appreciated functionalities on the readout side of AFM-b

144 terogeneity within and between organs, while appreciated, has not been analyzed in detail.

145 ntegrated with the O(2) transport pathway to appreciate how local and systemic vascular control helps

146 We now can appreciate how multisensory integration can alter patter

147 itate proliferation; however, it is not well appreciated how this enables senescence bypass.

148 What is not widely appreciated, however, is how the use of such synthesized

149 It is seldom appreciated, however, that object constancies must also

150 stem in vaccine-induced protection is widely appreciated; however, our understanding of how antibody

151 To appreciate human-technology interaction in the clinical

152 t profile is substantially more complex than appreciated, identifying 38 novel exons and 241 novel tr

153 E-deficiency is much broader than previously appreciated; ii) neutralizing autoantibodies to type I i

154 much greater extent than has been previously appreciated, implicating phase separation as an evolutio

155 Role of chemokines is well appreciated in cancer, including OvCa.

156 This point is under-appreciated in current scientific and media discussions

157 Total loss of a and b wave of both were appreciated in electroretinography (ERG).

158 effects of tumorigenesis that are now being appreciated in epimorphic regeneration, including geneti

159 dus gonads are gastronomic delicacies widely appreciated in Europe.

160 Such functional diversity has been appreciated in gene expression studies, functional assay

161 effect of algorithm-augmented care was best appreciated in patients with lesions satisfying only 1 c

162 effect of algorithm-augmented care was best appreciated in patients with lesions satisfying only one

163 lacking RIPK1 and RIPK3, which has not been appreciated in prior studies.

164 napse function have also become increasingly appreciated in recent years.

165 acterial effects in vivo, far beyond what is appreciated in standard bacteriological susceptibility t

166 genes in MCI and AD that were not previously appreciated in terms of their indication of systems-wide

167 The present preclinical data, appreciated in the context of published 5-HTP clinical d

168 portance of CD4+ T helper (Th) cells is well appreciated in view of their essential role in the elici

169 e change) against the rate at which spending appreciates in value (e.g., through interest, learning,

170 f B cells in HIV-1 infection than previously appreciated, including antigen-inexperienced cells.

171 er repertoire of transcripts than previously appreciated, including HNRNPD and HNRNPDL, which are inv

172 se cardiovascular conditions than previously appreciated, including valvular heart disease.

173 However, it is appreciated increasingly that most chronic itch disorder

174 Burn injuries are under-appreciated injuries that are associated with substantia

175 velopmental trajectories provide a guide for appreciating interneuron diversity and argue that subtyp

176 velopmental trajectories provide a guide for appreciating interneuron diversity and argue that subtyp

177 Less appreciated is how the tropical Atlantic and Indian Ocea

178 Less appreciated is that the extent and free-energy cost of t

179 proper control of body metabolism, but less appreciated is that these cells naturally interact with

180 us female mutational processes; what is less appreciated is that they also reflect chromosome-level b

181 Less well-appreciated is the body of evidence demonstrating that s

182 vious component of starvation survival, less appreciated is the importance of the ability to recover

183 netically far more pervasive than previously appreciated; it is possible that the very first animals

184 y, and summarize a set of ideas that help us appreciate its physics in diverse circumstances.

185 on of body weight and energy balance is well appreciated, little is known about the transcription fac

186 ced T-cell plasticity, a factor increasingly appreciated, may partially explain these divergent resul

187 s evolution, highlighting a previously under-appreciated mechanism of genome expansion in archaea.

188 ed, these observations expose a so far under-appreciated mechanism of how cells of the immune system

189 The appreciated mechanism of protection by HA stalk-reactive

190 nd understanding these differences is key to appreciating metabolic diversity, and to attempts to eng

191 tinal microbiome and in contrast to its well-appreciated microbiome-dependent protective role in inte

192 d ongoing neuroplasticity with an arc toward appreciating neuron-glial interactions and the role that

193 Edible mushrooms constitute an appreciated nutritional source for humans due to their l

194 rC-ADC by identifying metastatic disease not appreciated on anatomic imaging, leading to changes in s

195 s great phenotypic variability, which can be appreciated only by examining multiple family members.

196 ue has been studied for decades, it has been appreciated only in the past 5 years that extensive arbo

197 specific amino acid stereoisomers have been appreciated only recently.

198 sity of regulatory information than has been appreciated previously, imposing constraints on regulato

199 d cell toolkit is more ancient than has been appreciated previously.

200 ities to combat influenza that have not been appreciated previously.

201 We focus on the under-appreciated property that many - perhaps most - collecti

202 We highlight the critical need to appreciate risk effects at each level in the chain of ev

203 A recently appreciated risk factor for HCC is the growing problem o

204 -associated microbiomes play an increasingly appreciated role in animal metabolism, immunity and heal

205 res present on the cell surface, have a well-appreciated role in human physiology, including sweeping

206 The most widely appreciated role of DNA is to encode protein, yet the ex

207 Here, we highlight recently appreciated roles for histone ubiquitination in DNA meth

208 In this review, we highlight more recently appreciated roles for lipids, particularly cholesterol a

209 of the miRNA has gained attention for newly appreciated roles in regulating target specificity and r

210 Despite the well-appreciated roles of intestinal microbiota in driving in

211 reservoir has important, and hitherto under-appreciated, roles in both within- and between-host vira

212 ls PPI to be a combination of the previously appreciated scaling of the startle response, as well as

213 97% of total volatiles, were associated with appreciated sensory properties, with alpha-pinene as the

214 horisations so that prescribers and patients appreciate shortcomings in the evidence about actual cli

215 ythms in inflammatory lung disease have been appreciated since ancient times.

216 The beauty of the eukaryotic cilium has been appreciated since electron microscopy first revealed its

217 es and their sequence conservation have been appreciated since mammalian genomes were first sequenced

218 ead and diverse L5 efferents than previously appreciated, suggesting a generalizable role for this co

219 h inflammatory pathologic conditions, we now appreciate that autophagic components participate in non

220 scination with cellular structures I came to appreciate that cells exhibit dynamism across all scales

221 s during the past few years, we have come to appreciate that typical Weyl semimetals host many Weyl p

222 Although it is well appreciated that antibiotics substantially alter the gut

223 It has become increasingly appreciated that autoimmune responses against neuronal c

224 While it is now appreciated that certain long noncoding RNAs (lncRNAs) h

225 It is increasingly appreciated that common analgesic mechanisms for these t

226 Furthermore, it is appreciated that endothelial adhesion molecules are heav

227 It has long been appreciated that genetic analysis of fetal or trophoblas

228 Although it is well appreciated that genetic studies of flowering time regul

229 It has long been appreciated that highly autoreactive BCRs are actively r

230 It is becoming widely appreciated that human perceptual decision making is sub

231 It is now appreciated that in addition to their role in humoral im

232 However, it is now appreciated that KRAS can promote the tumor growth via u

233 It's widely appreciated that liquid-liquid phase separation (LLPS) u

234 It is recently appreciated that many bacterial chemoreceptors have liga

235 It is now appreciated that pancreatic susceptibility gene alterati

236 It is well-appreciated that patients with documented penicillin all

237 It has been long appreciated that sex hormone receptors are expressed in

238 Recently, it has been increasingly appreciated that sex steroids also play an important rol

239 It is increasingly appreciated that some evolutionary questions can only be

240 It is widely appreciated that sympathetic stimulation of the heart in

241 More recently, it has been appreciated that T cells need to accommodate increased m

242 It is generally appreciated that terrestrialization required adaptive ch

243 It is widely appreciated that the functional capabilities of multisit

244 It is being increasingly appreciated that the immunomodulatory functions of PARP1

245 It is not widely appreciated that the ion-exchange process that creates t

246 Recently it has become appreciated that the problems should be addressed, and w

247 It is now widely appreciated that the spatial organization of the genome

248 It has long been appreciated that these changes in the cardiac ECM result

249 Over the past decade, it is now appreciated that these tumors are composed of numerous d

250 While it has long been appreciated that transcriptional pathways are dysregulat

251 encourages a context-sensitive approach that appreciates that individuals and groups can both matter.

252 atterns of social evolution as well as fully appreciate the biological implications of the switch fro

253 d to fully understand CM, it is essential to appreciate the complex relationship between the malarial

254 More recently, we have come to appreciate the critical interaction between the brain an

255 tices among chimpanzees, can help the author appreciate the distinctive character of this behaviour a

256 To appreciate the diverse roles of ADP-ribosylation across

257 To appreciate the diverse ways in which immunologists have

258 Since we are just beginning to appreciate the extent to which phenotypic variation due

259 ies are a warning that we may have failed to appreciate the full scale and pace of environmental degr

260 To fully appreciate the function and regulation of these neurotra

261 ill help the interpreting physician to fully appreciate the implications of the scintigraphic finding

262 As I look back I've come to appreciate the importance and joy that can come from bei

263 the success of microRNA (miRNA) research and appreciate the importance of posttranscriptional gene re

264 s in the study of complex disorders to fully appreciate the large biological heterogeneity present in

265 branes plays a key role on the road to fully appreciate the physiological functions of this fundament

266 infer glucose metabolism, it is relevant to appreciate the potential limitations of 2-FDG as a surro

267 er is expanding so that a broad audience can appreciate the profound influence these developments may

268 er scientific field does not appear to fully appreciate the remarkable fact that normal development i

269 based on a level of generality that fails to appreciate the specific conditions of the Mongol invasio

270 We are beginning to appreciate the surprising versatility of viral genomes a

271 ut to define these, the clinician must first appreciate the trajectory of a biomarker from bench to b

272 ile families reported significant harm, many appreciated the donation attempt.

273 Appreciating the contributions of Forest Transitions to

274 Appreciating the interactions within and between hierarc

275 search, many tribal communities in Oklahoma, appreciating the potential benefits of genomic research,

276 se of 2-FDG PET to infer glucose metabolism, appreciating the potential limitations of 2-FDG as a sur

277 Although apparently not previously appreciated, the caudal ARC showed a far greater density

278 importance of central melanocortins is well appreciated, the genetic program that establishes and ma

279 of volatile anesthetics have been growingly appreciated, the molecular mechanism has not been unders

280 oid-lysophospholipids have been increasingly appreciated, the signaling functions of eicosanoid-lysop

281 viruses provides the structure necessary to appreciate their biological diversity.

282 ent mechanisms in different contexts, and we appreciate their effort to assess whether the transmissi

283 We appreciate their general enthusiasm for our findings, bu

284 meric GluN1/2B/2D receptors are necessary to appreciate their physiological roles in neural circuit f

285 graphs are visualized in 3D space to better appreciate their sometimes large and complex topology, w

286 m overload on mitochondrial function is well appreciated, there has been little to no reports on the

287 y in controlling enzymatic processes is well appreciated, there is a current dearth in our understand

288 To appreciate this challenge, this would require finding te

289 tic disease modifier and highlights an under-appreciated time window for such therapeutic interventio

290 Lipid metabolism is increasingly being appreciated to affect immunoregulation, inflammation and

291 te epigenetic and signaling pathways are now appreciated to have instructive rather than bystander ro

292 The cerebellum is well appreciated to impart speed, smoothness, and precision t

293 Hypoxia and glycolysis have long been appreciated to promote immune cell activation.

294 Obesity is well-appreciated to result in poor cardiovascular and metabol

295 microbial expansin proteins may be an under-appreciated virulence factor for many pathogen species.

296 Users appreciated water trucking, especially compared to previ

297 , and cortical thickness in newborn voles to appreciate when differences in HC and LC offspring begin

298 ficant limitations which need to be properly appreciated when deciding how to best use them to guide

299 ic at the membrane interface than previously appreciated, which may be important for both its physiol

300 n neuropsychiatric disorders is increasingly appreciated, yet data from disease brains are conspicuou