ライフサイエンスコーパス: approach

1 sport practice by means of a new "correction approach".

2 signalling may provide an immunotherapeutic approach.

3 in order to help identify the highest yield approach.

4 ensitivity, it remains a costly and invasive approach.

5 g a Bayesian Metric Multidimensional Scaling Approach.

6 t 6 months after enrollment using a landmark approach.

7 ted exon skipping is a promising therapeutic approach.

8 when it is advantageous to use the FLOW-MAP approach.

9 e inter-individual heterogeneity with either approach.

10 n of the protein corona using an immunoassay approach.

11 binding obtained using a crystal engineering approach.

12 aced on the necessity of a multidisciplinary approach.

13 ing a synergistic experimental-computational approach.

14 ing a low-cost, fast and accurate diagnostic approach.

15 ous architectural components in the authors' approach.

16 ools developed using our RNA-As-Graphs (RAG) approach.

17 ts coupled to a novel bioinformatic analysis approach.

18 al use and call for different Treg depletion approaches.

19 ons of the available colocalization analysis approaches.

20 nt conditions and require peculiar synthetic approaches.

21 analyses with mid/high-throughput culturing approaches.

22 ortality were compared using competing risks approaches.

23 or probiotics might offer better therapeutic approaches.

24 imited studies on interspecific grafting and approaches.

25 nical trials and offers direction for future approaches.

26 compared to 20-30% error when using current approaches.

27 the need to fill data gaps using read-across approaches.

28 icult to achieve by conventional fabrication approaches.

29 of novel substrates by combining additional approaches.

30 Using this approach, a wide array of polycyclizations are achieved,

31 s distinguish 2 categories of predictive HTE approaches: a "risk-modeling" approach, wherein a multiv

32 rogate of noble gas MRI and to validate this approach across a wide range of lung diseases.

33 The efficient ligand-based design approach adopted demonstrates its versatility in generat

34 In this project, we demonstrate a novel approach aimed at protecting islets before Tx in nonhuma

35 therapeutic targets and putative therapeutic approaches aimed at resolving detrimental myeloid cell r

36 Therapeutic approaches aiming to destabilize MYCN protein, such as s

37 gether, these computational and experimental approaches allow assessment of critical microenvironment

38 ble Isotope Labeling in Cell culture (SILAC) approaches allow measurement of protein dynamics, includ

39 In addition, the approach allows exquisite control over the patterned sub

40 This approach also allows easy phase transfer of the PQDs fro

41 Our approach and results thus contribute to a deeper underst

42 asia (PanIN), along with several biochemical approaches and immunofluorescence microscopy analyses, w

43 search pipelines that broaden evidence-based approaches and the pathobiology of these novel events.

44 Current diagnostic approaches are based on discordant measures, suffer from

45 However, current approaches are entirely data driven and agnostic to evol

46 Current approaches are mainly focused on searching for statistic

47 ase remains poor, and thus novel therapeutic approaches are needed.

48 We show that whereas spatial approaches are relatively common, spatial replication is

49 ruses and support further evaluation of this approach as a potential addition to Ebola vaccine develo

50 Among the myriad of approaches attempted to engineer solid organs, 3D biopri

51 By contrast, sleep deprivation studies using approaches avoiding novelty-induced arousal (i.e., gentl

52 In this study, we designed an experimental approach based on potentiometric titrations to determine

53 Instead we recommend a topographic approach based upon OCT probability maps and a 10-2 VF.

54 Approaches based on compacted de Bruijn graphs to identi

55 index reaction(s), as well as an algorithmic approach, based on cross-reactivity studies, in patients

56 d in 10.3% of these patients, and a Bayesian approach (BeviMed(4)) identified multiple new candidate

57 n the data, quantified in modern statistical approaches by the likelihood function.

58 e basis of these results, we devise a simple approach, called UVHis-PAGE, that uses metal ion-loaded

59 Here, we show that this toughness design approach can be applied to synthetic adhesives.

60 on of sponge cakes and demonstrates how this approach can be used to improve the sensory perception o

61 The study showed how the developed approach can be used to study the heterogeneous properti

62 ough extensive simulations, showing that our approach can deliver accurate estimates of selection coe

63 We demonstrate which stages of the approach can extract meaningful information, and also de

64 imaged with (18)F-FAC PET to assess if this approach can monitor the effect of an immunomodulatory d

65 has been hindered by a lack of experimental approaches capable of detecting and quantifying lateral

66 Given the robustness of the approach, CARP would be particularly suitable for dissec

67 All of these covalent labeling approaches combine to constitute a problem-solving toolb

68 us environments through a full spectrometric approach combined with a simulation and data fitting met

69 Our approach combines serial affinity purification, live cel

70 total hip arthroplasty, an anterior surgical approach compared with a posterior or lateral surgical a

71 f things) and maintenance of anonymity, this approach could ultimately facilitate near-real-time diag

72 no-engineering and biomaterial encapsulation approach, could therefore offer key advantages for clini

73 Existing approaches describe the fusion of cell aggregates by ana

74 We then introduce a new approach designed specifically to find radically distrib

75 2D and detail how we and others are applying approaches developed for T2D to the study of heterogenei

76 ul means to prevent LD progression, but this approach did not reduce brain glycogen or LBs to levels

77 Pharmacologic and probiotic approaches directed towards specific TLR2 signaling proc

78 Moreover, as this approach does not depend on the use of agents like lucif

79 Current approaches either identify driver genes on the basis of

80 Our approach endows soliton microcombs with integrated, ultr

81 This approach enumerates five domains of evaluation-(1) medic

82 Using a training-testing approach, epigenome-wide CpGs associated with asthma wer

83 Further, we demonstrate our approach experimentally on a superconducting quantum pro

84 Here, we developed a piecewise approach for all-atom steered molecular dynamics simulat

85 RD spectroscopy is a noninvasive, label-free approach for assessing conformational changes in recepto

86 ry relevant clinical setting and a realistic approach for assessing potential therapeutics.

87 This work provides a promising approach for constructing reaction-based chemosensors us

88 rential expression analysis is a widely used approach for detecting genomic biomarkers.

89 We demonstrate the power of this approach for detection applications by quantifying a bro

90 The applicability of this approach for drug delivery, bioimaging, and cell targeti

91 rt-led process for developing a standardized approach for establishing benchmarks for relevant outcom

92 se altering CTCF sites and provides a simple approach for functionally annotating the regulatory cons

93 show the value of model-guided design as an approach for generating useful DNA parts.

94 Here, we present a novel approach for in situ extraction of organic compounds fro

95 odulation of reward learning may be a viable approach for novel interventions in bipolar disorder.

96 is and transport, but the main computational approach for predicting metabolic network fluxes, flux b

97 In this study, we describe a new approach for preparing islets that enhances islet functi

98 Urine diversion has been proposed as an approach for producing renewable fertilizers and reducin

99 plicability of an untargeted, activity-based approach for SCRA detection in OF.

100 strating that thermal imaging is a promising approach for the clinical assessment of lesion activity

101 escribe a novel high throughput, micro-macro approach for the identification and efficient design of

102 The proposed method was seen to be a useful approach for the quantification and identification of po

103 epresent a mechanistically novel therapeutic approach for the treatment of affective and stress-relat

104 . aeruginosa behavior, and may inspire novel approaches for controlling P. aeruginosa infections.

105 his understanding may lead to new targets or approaches for drug development or treatment regimens th

106 the development of scientific and regulatory approaches for evaluating bioactivity.

107 Current approaches for handling the so-called missingness have c

108 e the potential for personalized therapeutic approaches for slowing clinical progression of AD.

109 Currently no approaches for using in vitro data to anticipate such in

110 dation or inducing memory extinction are two approaches for weakening maladaptive memories in disorde

111 one can exploit using a crystal engineering approach, for example, the design of novel dynamic funct

112 Plant breeding would benefit from borrowing approaches found useful in other disciplines.

113 These approaches frequently propose high proportions of nonfor

114 ally manufactured outputs, toward integrated approaches from a design perspective is critically devel

115 On the basis of simulations, this approach has been argued to be safe for post hoc tailori

116 This approach has been successfully applied to spin, supercon

117 This approach has been used for the better part of a century;

118 gies in graphene using top-down lithographic approaches has proven to be challenging due to poor stru

119 ian systems at the organism level-a top-down approach-has led to definition of unifying properties, a

120 ew, we summarize how different spectroscopic approaches have shed light on various aspects of these e

121 ere, we introduce a bespoke machine-learning approach, hierarchical statistical mechanical modeling (

122 We believe this new approach holds tremendous promise in reproducibly resolv

123 .8%) participants reported SSTI in Household Approach households, while 23 of 236 (9.7%) participants

124 ) participants reported SSTI in Personalized Approach households; difference in proportions -1.1% (95

125 This approach identified Endothelial differentiation-related

126 ress this, we develop Cyclum, an autoencoder approach identifying circular trajectories in the gene e

127 We hypothesized that this approach improves BPD risk assessment, particularly in e

128 Using a highly novel gene therapy approach in a canine, rapid atrial pacing model of AF, w

129 portions of the cervix using a transvaginal approach in eight postmenopausal and 25 premenopausal wo

130 emory Th17 cells may be a viable therapeutic approach in the treatment of age-related dry eye disease

131 ized such models by adopting a nonparametric approach in which group-level response trends for logari

132 such investigations have taken a 'black box' approach in which the internal structure of themodel use

133 s study sought to explore various analytical approaches in assessing total ischemic and bleeding even

134 red clinical trials have tested immune-based approaches in childhood cancers, few have been guided by

135 eotide-based drug platforms, focusing on key approaches - including chemical modification, bioconjuga

136 trate the practical utility of an integrated approach, including size exclusion chromatography with m

137 ion areas could benefit from this convenient approach, including the use of versatile, reduced-format

138 ess has been largely neglected by historical approaches independently and solely focusing on reaching

139 This symbiont-mediated RNAi approach is a tool for studying bee functional genomics

140 The approach is based on convolutional neural networks (CNNs

141 traditional antibody-based immunoassays, our approach is capable of monitoring in-situ activity of LA

142 ed to cell segmentation problems before, our approach is fundamentally innovative in that it also use

143 This approach is generalizable and can be applied to many mul

144 However, this therapeutic approach is often limited by the extent of CAR-T cell ex

145 Although regulatory approval of this approach is still pending, preparing the healthcare syst

146 the widely used days-per-degree sensitivity approach is subject to methodological issues that can ge

147 f bulk chemicals via a metabolic engineering approach it is necessary to better characterize both the

148 This approach makes customizable multiplex ultrasensitive ELI

149 This approach makes use of a reactive linker to form cyclic p

150 eased with increasing MoS(2)/clay ratios and approached maximum values of 0.09 and 0.06 nm/s in the b

151 Such an approach may be a general principle applicable to design

152 es, we further demonstrated that the present approach may be broadly applicable to proteins undergoin

153 The iTBS-gamma tACS approach may be potentially useful in rehabilitative set

154 The existing approaches may each have some severe limitations.

155 In a simplistic sense, such an approach mimics the modes of activation and control in e

156 Using this approach, myoblasts were phenotypically identified by th

157 n prior findings while avoiding the overused approach of assuming nothing.

158 may eventually be targeted in a personalized approach of chronic low-grade inflammation.

159 Sweden has taken a unique approach of not implementing strict closures, instead ur

160 y supported treatment guidelines, a stepwise approach of pelvic floor physical therapy and cognitive

161 The approach of performing regularisation as an add-on layer

162 However, these approaches often do not incorporate local environmental

163 iScore ranks among the top scoring approaches on the CAPRI score set (13 targets) when comp

164 We tested our proposed approach over two benchmark datasets.

165 artificial intelligence system for brain MRI approached overall top one, top two, and top three diffe

166 However, new sequencing approaches, particularly whole-genome sequencing (WGS),

167 5% in anode reversibility will require fresh approaches, perhaps borrowed from other fields.

168 an integrative crystallographic and chemical approach places quantitative constraints on mush pile th

169 axis and limb formation, thus validating our approach; plus, many other candidate RA target genes wer

170 del that can predict the lambdamax using our approach presented in our prior studies, we selected a s

171 variability using a multivariate data-driven approach (principal component analysis) on an extensive

172 Moreover, nanoscaffold-based approaches promote significant axonal growth and functio

173 This approach provides a new way to evaluate and constrain co

174 This approach results in the accurate identification of hundr

175 traditional neutral cobalt(I) catalysts and approach rhodium catalysts in activity are reported here

176 We call this approach "Scientific Regret Minimization" (SRM), as it f

177 The combined in vivo approaches showed that increased cerebral infiltration o

178 benefit from these integrative, multi-omics approaches since the kidney biopsy, blood and urine samp

179 However, the demonstrated approaches still require that the object is trapped at t

180 Xplorer, which uses a graph-based clustering approach streamlined by the integration of non-trivial s

181 animals compared to rodents, rendering this approach suboptimal for treatment of the global brain le

182 We discuss approaches such as neurostimulation and pharmacological

183 The ACA approach takes a step toward maximizing the capabilities

184 ctivity of p97 in real time via an NMR-based approach that allows us to follow the steps that couple

185 Here we develop a consistent metabolic approach that combines two complementary carbon accounts

186 Additionally, we find that an equation-free approach that does not presume a specific stock-recruitm

187 We present an approach that enables sensitive OA detection in presympt

188 By taking a comparative approach that exploits Drosophila neurogenetics, our res

189 ster Of Clusters Analysis (COCA) is one such approach that has been widely applied in the context of

190 Using a trait-based approach that incorporated genomic and phenotypic inform

191 The multi-target approach that is exemplified by these types of strategie

192 "litmus test" will be whether computational approaches that are successfully identifying groups of p

193 and sustainable resource management requires approaches that manage bodily excreta within coupled hum

194 hysalis and their hosts in the Neotropics to approach the tick-host relationships using a network-bas

195 ion states is generally high and remarkably, approaches the maximum possible power for this inference

196 Using this approach, the conventional three dimensional MR scalar i

197 Here we approach this problem by adapting the random-dot motion

198 We have approached this problem in mouse retina by analysing the

199 cs, showing an improvement of skill over LIM approaches, thus opening an avenue for environmental ris

200 sformation algorithm to provide an effective approach to achieving 3D sub-diffraction-limit informati

201 We propose an approach to allow one to increase the sensitivity of the

202 t G-CSFR blockade as a promising therapeutic approach to attenuate renal IRI.

203 etic therapy and immunotherapy an attractive approach to circumvent the limitations of immunotherapy

204 With a tailored architecture and an ensemble approach to CNN parameter interpretation, we show that o

205 irected immunotherapy, providing a promising approach to combinatorial immunotherapy for cancer.

206 omains, thus highlighting the ability of our approach to deliver insights into chromatin organization

207 tes (ADCs) developed as a targeted treatment approach to deliver toxins directly to cancer cells are

208 , we apply a high-resolution, pressure-based approach to describe how two fishes, bluegill sunfish (L

209 Overall, this systematic approach to drug repurposing lays the groundwork to stre

210 ugh their phenolic moiety represents a novel approach to enediyne ADC creation, while the pharmacolog

211 Moreover, a general approach to engender endogenous patient-specific cellula

212 We applied this approach to examine how a fungal pathogen affected the a

213 nority variants, and support the use of this approach to examine the impacts of minority HIV variants

214 dance, highlighting the applicability of our approach to facilitate image-based pooled CRISPR screens

215 e versatility of the enzyme, providing a new approach to facilitate novel applications.

216 Here, we applied a systems biology approach to gain deeper insights into the PCSK6 role in

217 c atypical forms of diabetes is an important approach to gaining insight and suggest that an insulin

218 s, the latter permitting a radiation chimera approach to help identify the CCL17 responding cell type

219 Objective: To develop an approach to identify additional AF-related genes by inte

220 hromatin accessibility mapping is a powerful approach to identify potential regulatory elements.

221 Here, we developed a machine-learning approach to identify small molecules that broadly correc

222 iciency and provides a prospective technical approach to improve the charge density, which could push

223 the dentate gyrus is a potential adjunctive approach to improve therapeutic efficacy of SSRI antidep

224 composition (DDD), an operator approximation approach to infer a continuous distribution map between

225 study revealed the potential of a structural approach to inform clinical efforts in targeting KRAS-G1

226 ical services to individuals is not a viable approach to meeting the mental health needs of a populat

227 The conventional pharmacological approach to mild asthma has long relied on reliever ther

228 Here, we present an approach to modulate extruded inks at the point of print

229 assays (IDAs) offer a unique and innovative approach to molecular sensing.

230 tumour cohort and develop a machine learning approach to molecularly classify and characterize tumour

231 ngs for COVID-19 vaccine development and our approach to optimizing for safety and efficacy.

232 What does a formal approach to population health science teach us about COV

233 on monitoring (MRM)-based targeted proteomic approach to quantify systemically the changes in express

234 This approach to quantifying reactivation risks will enable e

235 e have developed a transient-directing-group approach to reductive Heck hydroarylation of alkenyl ben

236 risk groups, necessitating an individualized approach to risk stratification.

237 We propose a sequential approach to sampling from the joint features population

238 using a deconvolved, confocal line scanning approach to score the distribution of the tsO45 mutant o

239 In summary, we introduce a novel statistical approach to systematically evaluate deleterious DNMs in

240 nd extensively characterized a head-specific approach to TBI in Drosophila, a powerful genetic system

241 colleagues take on an intensive experimental approach to test whether one potential stressor-limited

242 tion of pathogenesis and outline a practical approach to the evaluation of patients with suspected au

243 Here an alternative approach to the existing selective reverse INEPT FESTA (

244 As a proof of principle, we applied this approach to the malaria-causing parasite Plasmodium falc

245 An efficient synthetic approach to the tricyclic 1,7a-dihydro-1,3a-ethano-inden

246 ry domain, we used a genetic sparse labeling approach to track SGNs and found no differences compared

247 Kirigami structures provide a promising approach to transform flat films into 3D complex structu

248 Immunotherapy has emerged as a promising approach to treat cancer, however, its efficacy in highl

249 is emerging as a safe and effective targeted approach to treating many types of cancer.

250 Furthermore, we have used different approaches to analyze the differences between the parent

251 study, we integrate a number of experimental approaches to build a model that provides insights into

252 Here, we used quantitative kinetic approaches to determine the transient kinetics of recogn

253 mediates CD95 signaling, we applied genetic approaches to dissect the roles of caspase-8 in cell dea

254 te pH, and it used experimental and modeling approaches to elucidate such impacts in flow-electrode c

255 the interaction between LMA and electrolyte, approaches to enable operation of LMA in practical condi

256 f of concept for the repurposing of existing approaches to enable rapidly scalable epidemiologic data

257 iscern, calling for additional complementary approaches to establish functionality.

258 delivery, from internal genetic engineering approaches to external encapsulation and modification, a

259 used natural product and synthetic chemistry approaches to generate libraries of compounds, with some

260 iew ongoing challenges and discuss potential approaches to help advance the promotion of women in the

261 fy people at risk for AKI and to develop new approaches to improve AKI outcomes.

262 en immunosuppressive drugs and antimicrobial approaches to infection control.

263 Evaluating for non-pharmacologic approaches to managing symptoms and asthma-related cough

264 t, optimization, and applications of optical approaches to measure the spatial and temporal profiles

265 Applying synthetic signaling approaches to plants offers the promise of mitigating th

266 itical review and highlight several emerging approaches to promote tumor retention and limit systemic

267 Approaches to prostate cancer screening, diagnosis, surv

268 perimental and molecular dynamics simulation approaches to reveal a detailed mechanism.

269 n (AHA) diet recommendations and the Dietary Approaches to Stop Hypertension (DASH) with the risk of

270 y DEHP and emphasize the value of multiomics approaches to study microbiome-host interactions followi

271 Current approaches to synthesize pai-conjugated polymers (CPs) a

272 Population genomics offers innovative approaches to test hypotheses related to the source and

273 has resisted conventional structural-biology approaches, to obtain atomic models of multiple protein

274 Our approach uses two independent adaptive evolution steps t

275 e advantages, and potential pitfalls, of the approach using a birth-death model with both synthetic a

276 Anchovies were found to respond to approaching visual looming stimuli at expansion rates th

277 t lack of third-line treatment options, this approach warrants consideration in the clinical manageme

278 A multi-analytical approach was adopted, combining non-invasive techniques,

279 ompared with a posterior or lateral surgical approach was associated with a small but statistically s

280 In this study, an integrated approach was developed to map the epitope/paratope of PD

281 A novel approach was employed to quantify and value nitrogen red

282 Non-inferiority of the Personalized Approach was established for the primary outcome 3-month

283 The SPS/ETD approach was implemented on an Orbitrap Tribrid mass spe

284 Our integrative approach was predictive of IA (area under the receiver o

285 l tissue perioperatively, and a conservative approach was taken.

286 NMR metabolomics approach was used to distinguish fresh and thawed Atlant

287 Using a machine learning approach, we built gene expression-based models to predi

288 Through this approach, we find that cholesterol in the target membran

289 Using a high-throughput approach, we have directly identified specific metabolit

290 To demonstrate the feasibility of this approach, we have used the antihistamine agent loratadin

291 To illustrate the approach, we investigated structural brain-behavior asso

292 Here, using a phylogenetic comparative approach, we study the evolution of the thermal sensitiv

293 Here, using molecular dynamics simulation approaches, we found that both OTUB1 and OTUB2 display a

294 Using genetic and pharmacological approaches, we show that depletion of the hyaluronic aci

295 trimental effects across all tested modeling approaches when metabolite time course data were missing

296 riation in benefit, and an "effect-modeling" approach, wherein a model is developed on RCT data by in

297 predictive HTE approaches: a "risk-modeling" approach, wherein a multivariable model predicts the ris

298 This approach will be widely applicable to all families of po

299 n urgent need to complement this traditional approach with experiments that probe proteins in a T-dep

300 y an independent committee using an adaptive approach with interim analyses.