ライフサイエンスコーパス: arbor

1 effectors to sculpt the developing dendritic arbor.

2 or whether they spread across the dendritic arbor.

3 tic synapses formed throughout the dendritic arbor.

4 lized compartment within a complex dendritic arbor.

5 mechanism to sculpt the developing dendritic arbor.

6 nel interactions across the active dendritic arbor.

7 hrough their propagation across the neuronal arbor.

8 DB6 bipolar cells via a sparse outer axonal arbor.

9 first stable branch point in the developing arbor.

10 due to the elongated shape of the dendritic arbor.

11 HCN channels in the distal apical dendritic arbor.

12 to form the eventual mature, branched ductal arbor.

13 atively regulate the growth of the dendritic arbor.

14 receptors throughout the elaborate dendritic arbor.

15 tress by preventing loss of D1-MSN dendritic arbor.

16 f glutamatergic synapses-along the dendritic arbor.

17 in restricted areas in the forming dendritic arbor.

18 successful AP propagation across the axonal arbor.

19 emergence and leads to impoverished terminal arbors.

20 r immense, architecturally complex dendritic arbors.

21 ckdown on mTOR pathway activity and dendrite arbors.

22 receive synaptic inputs on extensive neurite arbors.

23 erminals onto staggeringly complex dendritic arbors.

24 to reveal the fine structure of mouse Muller arbors.

25 sible cue from a distance to shape dendritic arbors.

26 the selective removal of branches from axon arbors.

27 de to precisely target and pattern dendritic arbors.

28 tion and reconstruction of long-range axonal arbors.

29 FF RGCs lose complexity more rapidly than ON arbors.

30 tion of synaptic inputs and outputs on these arbors.

31 pression and promotes more complex dendritic arbors.

32 in part from the morphology of the dendritic arbors.

33 nd hippocampal neurons had smaller dendritic arbors.

34 asis during morphogenesis of large dendritic arbors.

35 neurons to form cell type-specific dendritic arbors.

36 al cells and the relative positions of their arbors.

37 wth in neurons with different-sized dendrite arbors.

38 ders (ASDs) are linked to abnormal dendritic arbors.

39 ent and the maintenance of established basal arbors.

40 of Rem2 reduced directionality of dendritic arbors.

41 tiple motor pools with overlapping dendritic arbors.

42 ynaptic communication over sprawling neurite arbors.

43 d that motor pools exhibit diverse dendritic arbors.

44 nd maintaining mitochondria throughout their arbors.

45 displayed stunted, poorly branched dendritic arbors.

46 st human- and animal-origin H2 viruses A/Ann Arbor/6/1960 (H2N2) (AA60) and A/swine/MO/4296424/06 (H2

47 mperature-sensitive master donor virus A/Ann Arbor/6/1960 and HA/NA gene segments from circulating vi

48 During serial passage of A/Ann Arbor/6/1960 at low temperatures to select the desired a

49 protein genes of the cold-adapted (ca) A/Ann Arbor/6/60 (H2N2) vaccine donor virus, which is the back

50 nfluenza A virus vaccine donor strain, A/Ann Arbor/6/60 ca (H2N2), the backbone of the licensed seaso

51 either the internal genes of the 1960 A/Ann Arbor/6/60 or the 1957 A/Leningrad/17/57 H2N2 viruses (i

52 y the Minnesota (MN) GVHD Risk Score and Ann Arbor (AA1/2) biomarker status.

53 ectrophysiological properties, for dendritic arbor anatomy as well as for short-term synaptic plastic

54 ection neuron with a nonstratified dendritic arbor and a descending axonal projection to tegmentum.

55 e, LASP2 exerts a distinct role in dendritic arbor and dendritic spine stabilization.

56 essive outcomes by reducing D1-MSN dendritic arbor and is sufficient to promote depressive-like behav

57 e describe new methods to apply quantitative arbor and network context to iteratively proofread and r

58 llings in and regression of the PC dendritic arbor and PC death) are likely to be primary and degener

59 n the theta range across the somatodendritic arbor and specific STA measurements were strongly relate

60 y arises from the structure of the dendritic arbor and the pattern of excitatory and inhibitory input

61 red for development of PVD and FLP dendritic arbors and can act as a diffusible cue from a distance t

62 rowth demands in neurons with large dendrite arbors and define Path as a founding member of this grow

63 demonstrate abnormal development of dendrite arbors and dendritic spines in newly generated dentate g

64 How information is organized across arbors and how local processing in neurites contributes

65 erneurons that form two stratified dendritic arbors and one stratified axonal arbor in the tectal neu

66 estigate the possible link between astrocyte arbors and presence of OPMs.

67 le methods for reconstructing 3-D microglial arbors and quantitatively mapping microglia activation s

68 Nes-cre Kdr(lox/-)) show decreased dendritic arbors and spines as well as a reduction in long-term po

69 oss caused progressive attrition of dendrite arbors and spines in Cornu Ammonis (CA)1 pyramidal neuro

70 nd molecular mechanisms that shape dendritic arbors and synaptic distribution, enabling J-RGC connect

71 acterized by a progressive loss of dendritic arbors and the emergence of impairments to learning-rela

72 tissue in the context of fully reconstructed arbors and to explore the spatial distribution of synapt

73 e literature (both national and local to Ann Arbor) and took into account coverage levels and effects

74 cant increases in striatum volume, dendritic arbor, and elevated excitatory synaptic markers in the c

75 ropean-American Lymphoma classification, Ann Arbor, and International Prognostic Index [IPI] scores)

76 omical arrangement of Muller cells and their arbors, and how these features arise in development.

77 Satb1 mutant mice, ooDSGC dendrites lack ON arbors, and the cells selectively lose ON responses.

78 Dendritic arbor architecture profoundly impacts neuronal connectiv

79 Axon arbor architecture, a major determinant of synaptic conn

80 Dendritic arbors are crucial for nervous system assembly, but the

81 chanisms that pattern and maintain dendritic arbors are key to understanding the principles that gove

82 Sensory dendrite arbors are patterned through cell-autonomously and non-c

83 The size and shape of dendritic arbors are prime determinants of neuronal connectivity a

84 tb2-RGCs and discovered that their dendritic arbors are relatively large and monostratified.

85 acterized, its effects on cortical dendritic arbors are still unknown.

86 re correctly partitioned onto a postsynaptic arbor, are incompletely understood.

87 nce cues, not molecularly distinct dendritic arbors, are a major determinant of dbd-A08a subcellular

88 nt regulates the morphology of the dendritic arbor, as well as the activity of the sensory neuron, in

89 gene permits extension of dendrite and axon arbors beyond these borders.

90 formation and was used by Abrupt to simplify arbor branching.

91 specifically in neurons with large dendrite arbors but not in other cells.

92 ude of synaptic inputs along their dendritic arbor, but how this highly heterogeneous population of s

93 ed at postsynaptic sites and along dendritic arbors, but whether this spatial arrangement affects the

94 e that delta-catenin regulates the dendritic arbor by coordinating the dynamics of individual dendrit

95 including the proper formation of dendritic arbors by forebrain neurons.

96 ial electron micrographs from which neuronal arbors can be reconstructed and synapses can be detected

97 AIVs) against clade 1 H5N1 viruses on an Ann Arbor cold-adapted (ca) backbone that induced long-term

98 nism is key to define and diversify dendrite arbor compartmentalization.

99 emonstrate a requirement for LPS in building arbor complexity and suggest a key role for pre-synaptic

100 Despite the reduction in axon arbor complexity seen in d-serine-treated animals, tecta

101 SPNs displayed reduced basal dendritic arbor complexity that was accompanied by chronic disturb

102 ls are critical in determining the dendritic arbor complexity, one of the possible ways being through

103 e required for spine stability and dendritic arbor complexity.

104 The architecture of dendritic arbors contributes to neuronal connectivity in the brain

105 The structure of axonal arbors controls how signals from individual neurons are

106 We found that regenerated arbors cover much less territory than uninjured neurons,

107 outposts during elaboration of the dendrite arbor creates a local system for guiding microtubule pol

108 The arbor densities are sorted into a number of clusters tha

109 ial distribution of the dendritic arbors, or arbor density, with reference to arbors of an abundant,

110 references (ON vs. OFF) varied across VG3-AC arbors depending on the laminar position of neurites, wi

111 A modification of the Ann Arbor descriptive terminology will be used for anatomic

112 However, the mechanisms of how dendritic arbors develop to promote functional and proper behavior

113 activity-regulated small GTPase Rem2 in both arbor development and the maintenance of established bas

114 hly detailed, quantitative analysis of basal arbor development that we believe has high utility both

115 anges in the structure of neuronal dendritic arbors disrupt proper circuit connectivity, which in tur

116 ut, while excitatory input did not vary with arbor distribution.

117 dcast as an unwavering binary pulse over its arbor, driving neurotransmission uniformly at release si

118 ity-dependent manner for sculpting dendritic arbors during early-use, critical period development of

119 axonal beta-actin mRNA translation disrupts arbor dynamics primarily by reducing new branch emergenc

120 to be critical for branch-specific dendritic arbor dynamics.

121 t retinal signaling is needed to support the arbor elaboration and synaptic connectivity of dLGN inte

122 nd by acting on neurons to enhance dendritic arbor elaboration.

123 d by acting on neurons to increase dendritic arbor elaboration.

124 tochemistry, we found that itch-sensing skin arbors exhibit free endings with extensive axonal branch

125 MVP2 arbors expand in Drosophila mutants null for fragile X m

126 s by Pesakou et al. tie daily cycles of axon arbor extension and retraction, mediated by Rho activity

127 retinal surface and evaluated the dendritic arbor extent and soma size of each cell according to its

128 At the morphological level, we find that TCA arbors fail to develop into discrete, concentrated patch

129 window at postnatal Days 6 to 9 when Muller arbors first colonize the synaptic layers beginning in s

130 uses the opposite outcome--reduced dendritic arbors following channelrhodopsin depolarization and exp

131 channelrhodopsin depolarization and expanded arbors following halorhodopsin hyperpolarization during

132 f synapses per connection, their overlapping arbors form ~8 million connections with ~37 million syna

133 ions in preventing the bundling of dendritic arbors from distinct neurons.

134 LS Clinic of the University of Michigan, Ann Arbor, from June 18, 2014, through May 26, 2016.

135 We found that the basal arbor grew substantially between postnatal day 7 (P7) an

136 cludes a period of exuberant branching where arbors grow in number, complexity, and field size.

137 cal T3 also dramatically increased dendritic arbor growth in neurons that had already reached a growt

138 system exhibit organ sparing at the level of arbor growth: Under nutrient stress, sensory dendrites p

139 mortality significantly increased as the Ann Arbor GVHD score increased.

140 the neurite connecting the cell body to the arbor - has a smaller volume.

141 Developing arbors have extensive acentrosomal microtubule dynamics,

142 ngs imply that neurons with larger dendritic arbors have improved encoding capabilities.

143 However, whether neurons with large dendrite arbors have specialized mechanisms to support their grow

144 nstrate that the density of YFP-labeled axon arbors hinders tracing of single axons to their point of

145 at the level of individual branches or whole arbors; however, no studies have attempted to quantify r

146 unmyelinated afferents that extend dendritic arbors hundreds of microns along the cochlear spiral, co

147 ion but then retracted and reorganized their arbor in a tangential direction away from the MZ soon af

148 ape the structure and function of the axonal arbor in mature sensory neurons in the main olfactory sy

149 that are prevalent throughout the dendritic arbor in neurons.

150 The development of the dendritic arbor in pyramidal neurons is critical for neural circui

151 ion neuron that forms a stratified dendritic arbor in the tectal neuropil and an axon that exits tect

152 d dendritic arbors and one stratified axonal arbor in the tectal neuropil.

153 s propagating along millimeter-length axonal arbors in cortical cultures with hundreds of microelectr

154 y of Mrgprd(+) nociceptors, while individual arbors in different locations are comparable in size.

155 By contrast, arbors in dLGN are compact (Krahe et al., 2011).

156 drites shows that the geography of dendritic arbors in relation to presynaptic partner terminals is a

157 amacrine cells that do not develop dendritic arbors in relation to the spatial positioning of such ho

158 approximately 110 min period, the dendritic arbor increases approximately 2.5-fold in size and migra

159 L) neuron, which extends elaborate dendritic arbors innervating the bases of taste hairs.

160 observed that some neurons segregated their arbors into input only and mixed input/output zones, tha

161 ital that, during development, the dendritic arbor is adequately formed to enable proper neural circu

162 Its spiny, highly branched dendritic arbor is bistratified, with dendrites restricted to the

163 The dendritic arbor is subject to continual activity-dependent remodel

164 w that the number of primary basal dendritic arbors is already established before eye opening, and th

165 Precise patterning of dendritic arbors is critical for the wiring and function of neural

166 The shape of their arbors is irregular but nonrandom, suggesting that local

167 cally assigned to the branches of remodeling arbors is not understood.

168 We show that the size of the dendritic arbors (its impedance load) strongly modulates the shape

169 Consistent with a repulsive role in arbor lamination, we observed complementary expression p

170 ells in vLGN versus dLGN had wider dendritic arbors, larger receptive fields, and fired with lower te

171 xperience has a modest net impact on overall arbor length (15%).

172 lacking gephyrin display increased dendritic arbor length and branching, increased spiny processes, d

173 Reduction of the dendritic arbor length and the lack of dendritic spines in the pyr

174 ed mice revealed that a net gain of only 15% arbor length could be attributed to visual experience; m

175 by the ON pathway, suggesting that their OFF arbor, like those of certain other ipRGCs, may receive e

176 Thus, VG3-AC arbors limit vertical and lateral integration of contras

177 While several known processes shape the arbor, little is known of those that govern dendrite bra

178 As arbors mature, they acquire excitatory and inhibitory sy

179 al Argus II Investigator Meeting held in Ann Arbor, MI in March 2015.

180 ants seen at the University of Michigan (Ann Arbor, MI, USA) provided plasma samples for measurement

181 versity of Michigan Rogel Cancer Center (Ann Arbor, MI, USA).

182 2011-2015; Truven Health Analytics Inc., Ann Arbor, Michigan) and the Nationwide Inpatient Sample (20

183 ansmission at a hypothetical hospital in Ann Arbor, Michigan, during a 1-year seasonal epidemic (June

184 logg Eye Center (University of Michigan, Ann Arbor, Michigan, USA) with a clinical diagnosis of an in

185 The urology departments in Ann Arbor, Michigan, USA, and Herlev and Gentofte, Copenhage

186 are practices in New York, New York, and Ann Arbor, Michigan.

187 transcriptional programs to create dendrite arbor morphological diversity for complex neuronal funct

188 Brn3c with Brn3a and Brn3b and the dendritic arbor morphologies and visual stimulus response properti

189 The arbor morphologies of brain microglia are important indi

190 ectional genetics, we describe the dendritic arbor morphologies of RGC types expressing Ret in combin

191 The arbor morphologies were quantified using Scorcioni's L-m

192 Dendritic arbor morphology is a key determinant of neuronal functi

193 Complete postganglionic arbors (n = 154) in the muscle wall were digitized and a

194 al integrity and complexity of the dendritic arbor of CA1 neurons that renders those cells permissive

195 The dendritic arbor of neurons constrains the pool of available synapt

196 Constructing the dendritic arbor of neurons requires dynamic movements of Golgi out

197 wers the development of the signal-receiving arbor of neurons that underlies neuronal network formati

198 ate synaptic integration along the dendritic arbor of pyramidal cells.

199 taset of 849 3D reconstructions of the basal arbor of pyramidal neurons collected across early postna

200 of neuronal TDP-43 granules in the dendritic arbor of rat hippocampal neurons.

201 aled that RNAs were delivered throughout the arbor of the sensory neuron, but that translation was en

202 ed to a small portion of the broad dendritic arbor of WF cells is sufficient to trigger dendritic spi

203 nile ganglion, which included the somata and arbors of all the neurons.

204 arbors, or arbor density, with reference to arbors of an abundant, well-defined interneuronal type.

205 sed complexity of apical and basal dendritic arbors of CA1 pyramidal neurons.

206 d to a reduced complexity of basal dendritic arbors of CA2 pyramidal neurons, but caused no alteratio

207 This activity colocalizes with arbors of commissural neurons, termed intertectal neuron

208 about the postnatal development of dendritic arbors of cortical pyramidal neurons and the influence o

209 of synaptic calcium signals along dendritic arbors of hippocampal neurons and relate this to measure

210 ruct the complete dendritic and local axonal arbors of identified corticogeniculate neurons in the ma

211 s of Golgi-stained brain sections, dendritic arbors of male hippocampal neurons are more complex than

212 cribe a method to map the location of axonal arbors of many individual neurons simultaneously via the

213 Dendritic and axonal arbors of many neuronal types exhibit self-avoidance, in

214 f this approach by reconstructing the axonal arbors of multiple neurons in the motor cortex across a

215 Although arbors of neighboring cells overlap extensively, imaging

216 Indeed, OFF arbors of ON-OFF RGCs lose complexity more rapidly than

217 Surprisingly, the central arbors of plantar paw and trunk innervating nociceptors

218 he skin to pattern the stereotypic dendritic arbors of PVD and FLP somatosensory neurons in Caenorhab

219 Dendritic arbors of retinal ganglion cells (RGCs) collect informat

220 of selective growth/elimination of dendritic arbors of RGCs driven by visual activity.

221 sider the relationship between the dendritic arbors of single VGluT3 cells and the distribution of th

222 rtebrate epidermal cells ensheath peripheral arbors of somatosensory neurons, including nociceptors,

223 Individual sympathetic axons formed complex arbors of varicose neurites within myenteric ganglia/pri

224 However, the arbors of very few long-range projection neurons have be

225 ses are distributed throughout the dendritic arbor, often hundreds of micrometers away from the soma.

226 s were found between maturation of dendritic arbors on the cellular level and the loss of diffusion a

227 in transition of the enigmatic NSC terminal arbor onto long cytoplasmic processes engaging with and

228 How a complex dendritic arbor optimizes this paucity of mRNAs opens several func

229 ndrite growth in neurons with small dendrite arbors or the animal overall.

230 ne the spatial distribution of the dendritic arbors, or arbor density, with reference to arbors of an

231 ites required for dendrite stabilization and arbor outgrowth.

232 ewer dendrite branches and shorter dendritic arbor over a 48 h imaging period.

233 Dendrite arbor pattern determines the functional characteristics

234 ing machine-learning-based quantification of arbor patterning with molecular-level tracking of cytosk

235 method detected 80.1 and 92.8% more centered arbor points, and 53.5 and 55.5% fewer spurious points t

236 highly accurate quantification of dendritic arbor position relative to neurites of other cells.

237 led and distributed throughout the dendritic arbor, potentially supporting a large learning capacity

238 tablished before eye opening, and that these arbors primarily grow through lengthening of dendritic s

239 terization of topological motifs in neuronal arbors provides a thorough description of local features

240 rphology, especially the shape of the axonal arbor, provides an essential descriptor of cell type and

241 n DG granule cells with simplified dendritic arbors, reduced dendritic spine density, and diminished

242 Arbor remodeling begins during the second postnatal week

243 s a multistaged process involving migration, arbor remodeling, and synapse formation.

244 adian rhythms in PDF accumulation and axonal arbor remodeling.

245 unipolar morphology with a single dendritic arbor restricted to the IPL.

246 bserved that the impairment of the dendritic arbor resulting from delta-catenin knockdown could be re

247 exclusively (i.e., approximately 100% of an arbor's varicose branches) to myenteric plexus ( approxi

248 l multiple mechanisms that shape a dendritic arbor.SIGNIFICANCE STATEMENT Visual perception begins in

249 Half decreased dendritic arbor size and Ca(2+) responses after dark and increased

250 Half increased dendrite arbor size and Ca(2+) responses following dark and decre

251 We then calculated the terminal arbor size and compared these measures with previously p

252 postsynaptic neuron without affecting total arbor size.

253 he retina with homogenous density, and their arbor sizes change little with eccentricity.

254 ed topographic variations in their dendritic arbor sizes.

255 Dendritic arbors spanned the length and/or width of vLGN and were

256 We find sublayer-specific arbor specializations within the inner plexiform layer (

257 in vivo, because Ndr2-null mutant mice show arbor-specific alterations of dendritic complexity in th

258 e stabilization of DG granule cell dendritic arbors, spines, and synapses, whereas it restricts the s

259 aking all patients into account, sex and Ann Arbor stage also seem to be DSS predictors.

260 on therapy, whereas DLBCL, MCL, and high Ann Arbor stage EMZL and FL were frequently treated with che

261 nts with primary OA-DLBCL were seen with Ann Arbor stage IE and TNM T2 disease.

262 ts with primary OA-DLBCL, 53 (93.0%) had Ann Arbor stage IE disease, and 4 (7.0%) had Ann Arbor stage

263 Localized Ann Arbor stage IE EMZL and FL were frequently treated with

264 Arbor stage IE disease, and 4 (7.0%) had Ann Arbor stage IIE disease.

265 5% confidence interval [CI], 1.26-2.33), Ann Arbor stage III or IV (HR, 1.79; 95% CI ,1.35-2.38), and

266 th previously untreated, advanced stage (Ann Arbor stage III or IV) follicular lymphoma of WHO histol

267 dy, patients aged 18 years or older with Ann Arbor stage III-IV follicular lymphoma were assigned 1:1

268 en taking all 100 patients into account, Ann Arbor stage was able to predict DSS (P = .01).

269 Most patients (76%) had Ann-Arbor stages III-IV and 96% of patients were treated wit

270 ctors included age (EMZL), sex (FL), and Ann Arbor staging classification (EMZL and FL).

271 = .04) in primary OA-DLBCL, whereas the Ann Arbor staging system was not.

272 h populations exhibited correlations between arbor stratification and aberrant inhibitory input, whil

273 TBI, we found marked Purkinje cell dendritic arbor structural abnormalities, which were comparable to

274 promote or restrict growth of the dendritic arbor; structural plasticity is achieved through a balan

275 ain system and suggest that regional central arbor structure could facilitate the "enlarged represent

276 Assessments of neurite arbor structure in vitro revealed CD2AP overexpression,

277 sed in neurons that extend complex dendritic arbors, such as Purkinje cells, targeted in SCA5 pathoge

278 th motor axon muscle targeting and dendritic arbor targeting, which are required for proper motor cir

279 pi, male neurons have more complex dendritic arbors than female neurons.

280 branching inside the nucleus and a dendritic arbor that differed from that of STN neurons without loc

281 MG postganglionics formed mixed, heterotypic arbors that coinnervated extensively (>15% of their vari

282 ligodendrocytes extend elaborate microtubule arbors that contact up to 50 axon segments per cell, the

283 this data set we measured the proportion of arbors that contained vesicles and the types of vesicles

284 elopment to increase the density of the TN1A arbors that interact with dendrites of the hg1 motoneuro

285 ere neurons form submicron synapses but have arbors that may span millimeters in length.

286 macrine cells (ACs) with elongated dendritic arbors that show orientation tuning.

287 lete neuronal morphologies, including axonal arbors that span substantial portions of the brain.

288 ns and individual thalamocortical axon (TCA) arbors that synapse with them.

289 ximizes the readiness of the entire neuronal arbor to respond to local cues.

290 positions, and their deployment of ramified arbors to cover specific neuropil territories to form a

291 inations, extend axons, and ramify dendritic arbors to establish functional circuitry.

292 erritories, whereas one expands its dendrite arbors to reach new partners.

293 that target the majority of their dendritic arbors to the scleral half or "Off" sublamina of the inn

294 Despite this extensive arbor, type II afferents are weakly activated by outer h

295 ilarities is capable of classifying neuronal arbor types as well as, or better than, traditional topo

296 Hospitalist Allied Research Program, and Ann Arbor Veterans Affairs/University of Michigan Patient Sa

297 The microglial arbors were reconstructed seamlessly using an automated

298 isturbances in maturation of their dendritic arbors, which further contribute to impaired cerebral gr

299 ossess myelinated distal dendritic tree-like arbors with excitable nodes of Ranvier at peripheral and

300 vered recurrent connections between neuronal arbors with mixed pre- and postsynaptic specializations.

301 elated to the restriction of their dendritic arbors within a single glomerulus (uniglomerular).

302 ndrite growth in neurons with large dendrite arbors without affecting dendrite growth in neurons with