ライフサイエンスコーパス: arbovirus

1 a medically important arthropod-borne virus (arbovirus).

2 ned, especially for arthropod-borne viruses (arboviruses).

3 sures acting on arthropod-borne RNA viruses (arboviruses).

4 st Nile virus, a globally-spreading zoonotic arbovirus.

5 pathogenesis associated with this reemerging arbovirus.

6 ssion for the biocontrol of Ae. aegypti-born arboviruses.

7 by which commensal microbes act on hosts and arboviruses.

8 e-off hypothesis may not be accurate for all arboviruses.

9 significant constraints on genetic change of arboviruses.

10 ntiviral defense in mosquitoes infected with arboviruses.

11 fer protection for Ae. aegypti against other arboviruses.

12 g globally without cross-reacting with other arboviruses.

13 ber of mosquito species are able to transmit arboviruses.

14 have important evolutionary implications for arboviruses.

15 or antiviral mechanism in arthropods against arboviruses.

16 and effect on mosquito vector competence for arboviruses.

17 ury associated with infection by neurotropic arboviruses.

18 y resembling that of other insect vectors of arboviruses.

19 ishmania, Bartonella bacilliformis, and some arboviruses.

20 n determining mosquito vector competence for arboviruses.

21 generate viral siRNAs when infected with RNA arboviruses.

22 alphaviruses and flaviviruses but not other arboviruses.

23 ose of potentially oncogenic, mosquito-borne arboviruses.

24 tor infection may constrain the evolution of arboviruses.

25 is a major vector of Zika, dengue, and other arboviruses.

26 e reservoirs and transmitters of hundreds of arboviruses.

27 uld potentially be extended to curtail other arboviruses.

28 al bacterium that promotes permissiveness to arboviruses.

29 dered these mosquitoes highly susceptible to arboviruses.

30 regulate the susceptibility of mosquitoes to arboviruses.

31 , with four of them being primary vectors of arboviruses.

32 y be useful to anticipate epidemic spread of arboviruses.

33 ed to assess the public health risk posed by arboviruses(3).

34 Chikungunya virus (CHIKV) is a reemerged arbovirus, a member of the Togaviridae family.

35 ion for the T/BG such as M. tuberculosis and arboviruses, a surprisingly high number of cases were as

36 des albopictus, a vector of dengue and other arboviruses, abolished the transmission capacity of deng

37 These results suggest that arbovirus adaptation and evolution is limited by obligat

38 expansion and vectorial capacity for various arboviruses affect an increasingly larger proportion of

39 Sindbis virus, an arbovirus and prototypic alphavirus having an inner prot

40 nuisance and an efficient vector of certain arboviruses and filarial nematodes.

41 ons for susceptibility to three encephalitic arboviruses and found that replication of Old World and

42 mosquitoes could prevent the transmission of arboviruses and other human parasites.

43 Arboviruses and plant tumour promoters are other possibl

44 anticipated changes in global climate on the arboviruses and the diseases they cause poses a signific

45 BG group included Creutzfeldt-Jakob disease, arbovirus, and Mycobacterium tuberculosis.

46 ntations differed according to the infecting arbovirus, and whether patients with dual infection had

47 ic and wild animals, but it is as vectors of arboviruses, and particularly arboviruses of domestic li

48 resource for characterizing human and animal arbovirus antibody responses at cohort scale.

49 Mosquito-borne arboviruses are a group of heterogeneous viruses that ar

50 Mosquito-borne arboviruses are a major source of human disease.

51 Consequently, although arboviruses are able to successfully adapt to diverse ce

52 These four arboviruses are endemic in overlapping regions due to th

53 Most alphaviruses and many other arboviruses are mosquito-borne and exhibit a broad host

54 As these arboviruses are multi-host, multi-vector systems, predic

55 evolution observed in natural populations of arboviruses are not necessarily due to the need for the

56 Arboviruses are transmitted by distantly related arthrop

57 Arboviruses are transmitted by mosquitoes and other arth

58 Arboviruses are transmitted by specific vectors, and the

59 Arboviruses are transmitted to vertebrate hosts by bitin

60 The evolutionary origins of arboviruses are unknown because their typical dual host

61 Domestic arthropod-borne viruses (arboviruses) are single-stranded RNA viruses, the most c

62 Zika virus is an arbovirus (arthropod-borne virus) and a member of the fa

63 Nevertheless, arboviruses (arthropod-borne viruses) are capable of inf

64 Arboviruses (arthropod-borne viruses) represent quintess

65 Millions of people are infected each year by arboviruses (arthropod-borne viruses) such as chikunguny

66 This defines such an arbovirus as something whose transmission should be prev

67 Zika virus (ZIKV) is an arbovirus belonging to the genus Flavivirus (family Flav

68 g dominant lethal genes, the introduction of arbovirus-blocking microbes into mosquito populations, a

69 rict in Laos to evaluate its potential as an arbovirus bridge vector.

70 vatic Ae. malayensis population to act as an arbovirus bridge vector.

71 rammes and thereby augment efforts to reduce arbovirus burden in human populations globally.

72 n cycles constrain the evolutionary rates of arboviruses but not their fitness for either host alone.

73 His interests (always primarily arboviruses but now also rodent-borne viruses and bat-bo

74 as evolved to become an efficient vector for arboviruses but the mechanisms of host-pathogen toleranc

75 Transmission of arboviruses by the bite of infected mosquitoes can poten

76 Thus, an arbovirus can evade the host antiviral response by induc

77 e broader question of whether other emerging arboviruses can cause similar neurotropic effects throug

78 Chikungunya virus (CHIKV) is an arbovirus capable of causing a severe and often debilita

79 -sense RNA viruses, are globally distributed arboviruses capable of causing rash, arthritis, encephal

80 Recently, the spread of other arboviruses carried by invasive Aedes spp., such as Chik

81 Arboviruses cause acute diseases that increasingly affec

82 Zika virus (ZIKV), a previously little known arbovirus, caused an unprecedented outbreak in Latin Ame

83 Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal inflammato

84 gue virus (DENV), a common and widely spread arbovirus, causes life-threatening diseases, such as den

85 by Venezuelan equine encephalitis virus, an arbovirus causing neurological disease in humans and equ

86 PORTANCE Dengue virus is the most widespread arbovirus, causing an estimated 390 million dengue infec

87 Similar to infections caused by other arboviruses, CHIKV infections are most commonly detected

88 the mosquito vector is widespread and other arboviruses circulate endemically.

89 A promising candidate for arbovirus control and prevention relies on the introduct

90 ng Wolbachia strains are promising tools for arbovirus control, particularly as they have the potenti

91 Arboviruses cycle between, and replicate in, both invert

92 Arthropod-borne viruses (arboviruses) cycle between hosts in two widely separated

93 sease vectors because it transmits two major arboviruses, dengue and yellow fever, which cause signif

94 llness, including infections with two common arboviruses, dengue virus and chikungunya virus.

95 The period of highest arbovirus discovery coincided with a comprehensive progr

96 Dengue is the most prevalent human arbovirus disease in the world.

97 One strategy to reduce arbovirus disease is to reduce the mosquito's ability to

98 Mosquitoes transmit Plasmodium and certain arboviruses during blood feeding, when they are injected

99 that mosquitoes could be exposed to multiple arboviruses during one feeding episode.

100 case report data are essential to understand arbovirus dynamics, including spread and evolution of ar

101 des aegypti, an invasive mosquito vector for arboviruses (e.g. dengue, zika and yellow fever).

102 Arbovirus emergence in the human population typically re

103 and global expansion of A. aegypti promoted arbovirus emergence not solely through increased vector-

104 To investigate whether arboviruses encounter bottlenecks during dissemination i

105 Yellow Fever (YF) is an arbovirus endemic in tropical regions of South America a

106 Chikungunya virus (CHIKV) is an emerging arbovirus, endemic in many parts of the world, that is s

107 West Nile virus (WNV)-a mosquito-borne arbovirus-entered the USA through New York City in 1999

108 dynamics that might assist in understanding arbovirus epidemics.IMPORTANCE Arbovirus infections in B

109 ese findings have important implications for arbovirus evolution and will help elucidate the viral fa

110 These results support the hypothesis that arbovirus evolution may be constrained by alternating ho

111 rade-off hypothesis, the current paradigm of arbovirus evolution, proposes that cycling between verte

112 separately or in concert shape the course of arbovirus evolution.

113 and is caused by bluetongue virus (BTV), an arbovirus existing in nature in at least 26 distinct ser

114 different host environments, mosquito-borne arboviruses exploit sophisticated approaches, including

115 esting for different applications new to the arbovirus field.

116 of 25 vector-pathogen interactions involving arboviruses, filarial worms, bacteria, and malaria paras

117 stern equine encephalitis virus (WEEV) is an arbovirus from the genus Alphavirus, family Togaviridae,

118 determinants that facilitate transmission of arboviruses from a vector to a host.

119 Accordingly, freeing arboviruses from alternate replication via specializatio

120 a comprehensive array of medically important arboviruses from the Alphavirus, Flavivirus, and Bunyavi

121 gunya virus (ChikV), a reemerging pathogenic arbovirus, has been made by attenuating wild-type (WT) v

122 er links between climate change and emerging arboviruses have become more pressing.

123 Chikungunya virus (CHIKV) and related arboviruses have been responsible for large epidemic out

124 us infection in mosquitoes and suggests that arboviruses have evolved mechanisms to avoid stimulating

125 Arboviruses have made unexpected reappearances in recent

126 nges in the epidemiology of Culicoides-borne arboviruses have occurred since 1998, including the emer

127 Arthropod-borne viruses (arboviruses) have a long history of emerging to infect h

128 ugh this information is important to compare arbovirus/host interactions in different classes of arbo

129 ivirus: Flaviviridae) is the most widespread arbovirus in the world.

130 insight into ZIKV can be found by evaluating arboviruses in domestic animals, of which there are at l

131 y is both induced by and restricts disparate arboviruses in Drosophila intestines, providing insight

132 ing and has become the main vector for human arboviruses in Europe.

133 pectrum antiviral property of IFITMs against arboviruses in foreskin cells.

134 induced on viral infection to restrict human arboviruses in insects.

135 recipient in Brazil and the re-emergence of arboviruses in many areas of the world dictate the need

136 relation between apoptosis and resistance to arboviruses in mosquitoes, there is no direct evidence t

137 major role in the antiviral response against arboviruses in mosquitoes.

138 sight into the emergence and re-emergence of arboviruses in nature and an avenue for disease preventi

139 e drawn attention toward other cocirculating arboviruses in South America.

140 unprecedented outbreaks of Culicoides-borne arboviruses in southern Europe has been a significant po

141 (ZIKV) is an emerging arthropod-borne virus (arbovirus) in the genus Flavivirus that has caused a wid

142 oes are a persistent human foe, transmitting arboviruses including dengue when they feed on human blo

143 habits of cetaceans, immunologic exposure to arboviruses including West Nile virus and Eastern equine

144 Aedes aegypti is vector of many arboviruses including Zika, dengue, yellow fever, West N

145 Arthropod-borne viruses (arboviruses), including those vectored by mosquitoes, ha

146 Global arboviruses, including dengue virus, Zika virus, and chi

147 The Aedes aegypti mosquito transmits arboviruses, including dengue, chikungunya, and Zika vir

148 pe flies are refractory to oral infection by arboviruses, including Sindbis virus and vesicular stoma

149 sponse and whether this is effective against arboviruses, including those with double-stranded RNA (d

150 Abundance of two key vectors of several arboviruses, including WNV, Culex tarsalis and the Culex

151 in vectors for dengue virus (DENV) and other arboviruses, including Zika virus (ZIKV).

152 take a blood meal is not known; however, an arbovirus-infected mosquito can inoculate extravascular

153 However, apoptosis is rarely seen in arbovirus-infected mosquito cells, raising questions abo

154 Aedes aegypti are vectors for several arboviruses infecting hundreds of millions of people ann

155 vice; 201 (14%) had symptoms consistent with arbovirus infection and sufficient samples for diagnosti

156 d the effect of stimulating apoptosis during arbovirus infection by infecting Aedes aegypti mosquitoe

157 Dengue is the most common arbovirus infection globally, but its burden is poorly q

158 itt's lymphoma, and symptoms compatible with arbovirus infection have been seen immediately before th

159 that apoptosis is a powerful defense against arbovirus infection in mosquitoes and suggests that arbo

160 andidate for the prophylaxis or treatment of arbovirus infection in vulnerable populations, such as p

161 Since March 2016, CHIKV is the arbovirus infection most frequently diagnosed in Rio de

162 ly outbreak, nor that concurrent exposure to arbovirus infection or vaccination modified risk.

163 Patients positive for arbovirus infection presented with a broad range of CNS

164 Typical manifestations of arbovirus infection range from no symptoms, to meningiti

165 samples from 100 fatal cases with suspected arbovirus infection were tested for CHIKV, dengue (DENV)

166 et of genes that is rapidly transcribed upon arbovirus infection, including components of antiviral p

167 GN are expressed in several early targets of arbovirus infection, including dendritic cells (DCs) and

168 missive to and allow systemic and persistent arbovirus infection.

169 accine (TDV) against the world's most common arbovirus infection.

170 ry route through which mosquitoes acquire an arbovirus infection.

171 A unique facet of arthropod-borne virus (arbovirus) infection is that the pathogens are orally ac

172 le drugs that have the potential to mitigate arbovirus infections and disease, yet this has not been

173 understanding arbovirus epidemics.IMPORTANCE Arbovirus infections in Brazil, including yellow fever,

174 women and children from Zika virus and other arbovirus infections is essential to preventing the deva

175 tides, similar to the viRNAs produced during arbovirus infections of mosquitoes.

176 Arbovirus infections varied by location and time of year

177 ission, and its interrelationship with other arbovirus infections.

178 could facilitate strategies for controlling arbovirus infections.

179 review recent progress on symbiotic microbe-arbovirus interactions and summarize the molecular mecha

180 ile virus (WNV), the world's most widespread arbovirus, invaded the United States in 1999 and rapidly

181 in developed countries, and various endemic arboviruses is essential.

182 nvestigation of HS binding by this and other arboviruses is warranted.

183 ution in the laboratory, but like many other arboviruses, it evolves at a relatively slow rate in the

184 It is caused by an arbovirus known as bluetongue virus (BTV).

185 Culicoides midges are important vectors of arboviruses, known to transmit pathogens of humans and l

186 t have been submitted for WNV testing to the Arbovirus Laboratories of the Wadsworth Center.

187 We grouped patients according to their arbovirus laboratory diagnosis and then compared demogra

188 The arbovirus life cycle involves viral transfer between a v

189 Arboviruses like dengue virus, yellow fever virus, and W

190 Here, we present an overview of the domestic arboviruses listed above and describe the modalities emp

191 Arthropod-borne viruses (arboviruses) mainly infect people via direct spillover f

192 Alphaviruses represent a diverse set of arboviruses, many of which are important pathogens.

193 In theory, cross species transfers by arboviruses may be constrained by their alternating infe

194 ons among arthropod vectors, microbiota, and arboviruses may offer new strategies for the prevention

195 ses, and in many cases mosquito-cell-derived arboviruses more efficiently infect DCs than viruses der

196 Our data highlight the complexity of arbovirus mutation-fitness dynamics and suggest that int

197 laria but are believed to transmit one known arbovirus, o'nyong-nyong virus, whereas Aedes mosquitoes

198 ican horse sickness virus (AHSV) is a lethal arbovirus of equids that is transmitted between hosts pr

199 Zika virus (ZIKV), an arbovirus of global concern, remodels intracellular memb

200 gue virus (BTV) is an economically important arbovirus of ruminants that is transmitted by Culicoides

201 Schmallenberg virus (SBV) is an emerging arbovirus of ruminants that spread in Europe between 201

202 achment receptors for Sindbis (SB) virus, an arbovirus of the Alphavirus genus.

203 is an emerging mosquito-borne (Aedes genus) arbovirus of the Flaviviridae family.

204 outbreaks of bluetongue virus in Europe, an arbovirus of wild and domestic ruminants also transmitte

205 as vectors of arboviruses, and particularly arboviruses of domestic livestock, that they achieve the

206 Aedes aegypti mosquitoes vector several arboviruses of global health significance, including den

207 Many emerging arboviruses of global public health importance, such as

208 Culicoides-borne arboviruses of livestock impair animal health, livestock

209 are abundant hematophagous flies that vector arboviruses of veterinary and medical importance.

210 Quaranfil virus (QRFV) is an unclassified arbovirus originally isolated from children with mild fe

211 No arboviruses other than dengue were identified.

212 ear, and were not always aligned with annual arbovirus outbreak seasons in different regions of the c

213 Increased frequency of arbovirus outbreaks in the last 10 years represents an i

214 molecules for arthropod-borne viruses, (ii) arbovirus particles produced in and delivered by arthrop

215 n vivo virus-host model system for exploring arbovirus pathogenesis and provides the first evidence f

216 While barriers limiting arbovirus population diversity have been observed in mos

217 bstantial evidence of temperature effects on arbovirus replication and dissemination inside mosquitoe

218 w for the first time that midge cells target arbovirus replication by mounting an antiviral RNAi resp

219 Our study reveals that blood meals enhance arbovirus replication in mosquitoes through activation o

220 To determine whether apoptosis can influence arbovirus replication in mosquitoes, we manipulated apop

221 ommon antiparasitic drug atovaquone inhibits arbovirus replication through intracellular nucleotide d

222 cific inhibitors both significantly impaired arbovirus replication.

223 As a result, low priority was given to arbovirus research investment and related public health

224 and important carriers of human malaria and arbovirus, respectively.

225 Chikungunya virus (CHIKV) is a reemerging arbovirus responsible for outbreaks of infection through

226 Arbovirus RNA detection by RT-PCR should be part of the

227 ification of coinfections, although targeted arbovirus screening may be sufficient in the current ZIK

228 Arboviruses seem to be associated with case clusters of

229 teroids, were more likely to have a positive arbovirus serology, were more likely to have a positive

230 enomes (referred to as 'replicons') from the arbovirus Sindbis [2].

231 We report that the Arbovirus Sindbis can be used to deliver high levels of

232 dering urban areas may provide a gateway for arbovirus spillback from humans to wildlife.

233 immunity could provide new tools to control arbovirus spread.

234 The continuing emergence of arboviruses such as chikungunya virus requires thoughtfu

235 Aedes mosquito-borne arboviruses such as dengue virus (DENV), Zika virus (ZIK

236 In particular, it is unclear why arboviruses such as dengue virus show substantial geneti

237 It is widely held that arboviruses such as the alphavirus Sindbis virus gain en

238 Arboviruses such as yellow fever virus (YFV) are transmi

239 dynamics, including spread and evolution of arboviruses such as Zika, dengue and chikungunya viruses

240 the Americas of VEEV and other encephalitic arboviruses, such as eastern equine encephalitis virus a

241 13], almost a year before it was detected by arbovirus surveillance program.

242 However, in some mosquitoes, arboviruses survive antiviral RNA interference (RNAi) an

243 ce ecological understanding of these complex arbovirus systems.

244 for the Reoviridae family, is a nonenveloped arbovirus that causes hemorrhagic disease in ruminants.

245 us (ZIKV) is a neurotropic and neurovirulent arbovirus that has severe detrimental impact on the deve

246 Rift Valley fever virus (RVFV) is an arbovirus that is classified as a select agent, an emerg

247 provides a unique opportunity to observe an arbovirus that is in decline and to better understand wh

248 Zika virus (ZIKV) is yet another arbovirus that is rapidly emerging on a global scale, on

249 virus (CHIKV) is a mosquito-borne arthralgia arbovirus that is reemergent in sub-Saharan Africa and S

250 Chikungunya virus is an emerging arbovirus that is widespread in tropical regions and is

251 yaviridae) is composed of a diverse group of arboviruses that cause disease syndromes ranging from mi

252 albopictus is a competent vector of several arboviruses that has spread throughout the United States

253 ti is the principal mosquito vector for many arboviruses that increasingly infect millions of people

254 infecting both mammals and insects just like arboviruses that use insect vectors to infect plants.

255 Alphaviruses are arthropod-borne viruses (arboviruses) that include a number of important human an

256 For other pathogens such as the arboviruses, the focus has been on prevention by vector

257 or, the susceptibility of disease vectors to arboviruses, the immunological control of infection in d

258 culation of Mayaro virus (MAYV), an emerging arbovirus threat, is essential for risk assessment but c

259 Arthropod-borne viruses (arboviruses) threaten the health of humans, livestock, a

260 viously uncharacterized mechanism used by an arbovirus to manipulate host immunity.

261 aracterized by the efficiency of an ingested arbovirus to replicate and become infectious in the mosq

262 This ability of arboviruses to infect arthropods and vertebrates is usua

263 is virus (LCMV), or the sand fly-transmitted arbovirus Toscana virus (TOSV).

264 ational exposure risk of mosquito biting and arbovirus transmission among outdoor worker populations

265 lls in investigations of the cell biology of arbovirus transmission and entry into mammalian hosts.

266 Understanding the role of the vector in arbovirus transmission has provided critical practical a

267 ntively 2 months before the beginning of the arbovirus transmission season.

268 tebrate viremia is a critical determinant of arbovirus transmission, geographic spread, and disease s

269 BTV is an arbovirus transmitted between its ruminant hosts by Culi

270 minants caused by bluetongue virus (BTV), an arbovirus transmitted by Culicoides.

271 AYV), causative agent of Mayaro Fever, is an arbovirus transmitted by Haemagogus mosquitoes.

272 Chikungunya, a re-emerging arbovirus transmitted to humans by Aedes aegypti and Ae.

273 Bluetongue virus (BTV) is an arbovirus transmitted to livestock by midges of the Culi

274 Other arboviruses transmitted by Ae. aegypti include the 2 fla

275 explosive nature of arthropod-borne viruses (arboviruses) transmitted by Aedes spp. mosquitoes(1,2).

276 ke viruses that undergo direct transmission, arboviruses utilize an arthropod vector (e.g., mosquitos

277 Implications for arbovirus vector competence in mosquitoes are discussed.

278 ere is no direct evidence tying apoptosis to arbovirus vector competence.

279 The mosquito Aedes aegypti is a major arbovirus vector native to Africa that invaded most of t

280 Aedes albopictus, another highly invasive arbovirus vector that has only been implicated in one co

281 nt-induced speciation, as well as control of arbovirus vectors and agricultural pests, the bacterial

282 onger (22 nucleotides) than those from other arbovirus vectors and mapped at highest frequency to the

283 resenting the two most significant genera of arbovirus vectors that infect people, were tested.

284 e small regulatory RNA pathways of the major arbovirus vectors, Ae. aegypti and Cx. pipiens, are evol

285 iviral RNAi between the two major classes of arbovirus vectors, and our data broadens our understandi

286 us/host interactions in different classes of arbovirus vectos.

287 n addition, there is only one other NT human arbovirus (Venezuelan equine encephalitis virus), which

288 re major transmission vectors for pathogenic arboviruses, viral infection has little impact on mosqui

289 ptides derived from all known vertebrate and arboviruses (VirScan).

290 ially important for arthropod-borne viruses (arboviruses) which belong to at least three virus famili

291 mount of genetic diversity compared to other arboviruses, which has been linked to increased virulenc

292 Aedes aegypti transmit pathogenic arboviruses while the mosquito itself tolerates the infe

293 n of vector range, the diagnosis of domestic arboviruses will become an increasingly important task f

294 Chikungunya virus (CHIKV) is an arbovirus with a high potential to spread globally.

295 Recoded arboviruses with a bias toward phylum-specific expressio

296 Theileria, and Anaplasma species, identifies arboviruses with the potential to transmit to humans.

297 Rift Valley fever virus (RVFV) is an arbovirus within the Bunyaviridae family capable of caus

298 renewed interest in monitoring and modeling arboviruses within mosquito vectors.

299 Dengue virus is the most common arbovirus worldwide and represents a significant public

300 Since 2015, the arthropod-borne viruses (arboviruses) Zika and chikungunya have spread across the