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1 nzo[h]quinazoline 7a-e as mixed analogues of archetypal 1,8-bis(dimethylamino)naphthalene ("proton sp
3 role-based systems on surfaces, we chose the archetypal 5,10,15-tris(pentafluorophenyl)corrole [H(3)(
4 tive representatives, including McClintock's archetypal Ac mobile genetic element, in many eukaryotic
8 collagen (Shc) proteins have been considered archetypal adaptors of epidermal growth factor receptor
9 case study, ABICAM simulated exposures of an archetypal adult and toddler over 24 h to diethyl phthal
10 better than Lewis acids as catalysts for the archetypal aldol cyclotrimerization of indanone (2) in a
12 Net, a comprehensive framework that combines archetypal analysis and manifold learning to provide a r
14 ,236,239 publications, and to apply a robust archetypal analysis to profile scientists across four ca
16 form of peptides and proteins represents an archetypal and widely accessible structure consisting of
17 o-EM) structures of Ca(v)1.1 in complex with archetypal antagonistic drugs, nifedipine, diltiazem, an
18 of recombinant TbPTR1 and inhibition by the archetypal antifolate methotrexate have been characteriz
20 vator of transcription (Tat) protein uses an archetypal arginine-rich motif (ARM) to recruit the host
22 asymmetric induction from 28 to 78% ee in an archetypal asymmetric allylation employing BINAP (L*) as
25 study analyzed GWAS data from a selection of archetypal autoimmune diseases among 138511 individuals
26 Familial Mediterranean fever (FMF) is an archetypal autoinflammatory disorder, which is autosomal
29 on a membrane-bound structural model of the archetypal bacterial VGSC, NaChBac in a closed pore conf
32 sm, we show that although autoxidation in an archetypal biogenic VOC system becomes more competitive
35 to identify transient reactive species of an archetypal C-H amination reaction catalyzed by a dirhodi
36 c phenotypes in the intestinal epithelium-an archetypal canonical, Wnt pathway-dependent, rapidly sel
38 nsisting of module 12, shown here to have an archetypal CCP structure, and module 13, which is unique
42 orks diverge significantly from those of the archetypal cis-AT type systems represent a new paradigm
44 Here we show that excitatory inputs to major archetypal classes of neocortical inhibitory neurons, fa
46 rge regions of genetic homogeneity among the archetypal clonal lineages, reflecting the relatively fe
60 resonant soft X-ray scattering, we study the archetypal cuprate La(2-x)Sr(x)CuO(4) (LSCO) over a broa
62 tivation of receptor-bound JAK2, based on an archetypal cytokine receptor, the growth hormone recepto
63 y to the differential effect of DELLA on the archetypal defense hormones salicylic acid (SA) and jasm
64 Pluripotent cells can be captured via the archetypal derivation of embryonic stem cells or via som
67 oscope tip polarizes an ultrathin film of an archetypal dielectric SrTiO(3) via flexoelectricity, whi
71 of the avalanche distributions vis-a-vis the archetypal dislocation mechanisms in face-centered cubic
73 mplexity RNA-binding sequences as well as an archetypal disordered RNP, fused in sarcoma, as model sy
75 Here we report thermal dust emission from an archetypal early Universe star-forming galaxy, A1689-zD1
76 but more recent AFM work suggested that the archetypal EcoKI protein went through an additional dime
81 us diseases of childhood, once thought to be archetypal environmental diseases, actually may be among
86 chain in a transverse magnetic field is the archetypal example of a system that undergoes a transiti
88 in macaque primary visual cortex, V1, as an archetypal example of cortical feature selectivity and d
89 essing; or (ii) decision-formation, using an archetypal example of global perception, coherent motion
90 ontrol network of teleost fishes presents an archetypal example of how a vertebrate nervous system pr
93 are demonstrated using a 4-site model and an archetypal example of the para-benzene ring and are show
96 o-dimensional, terephthalate linkers, is the archetypal example: both functionalized and elongated li
98 lastoderm and the vertebrate neural tube are archetypal examples of morphogen-patterned tissues that
100 diate acetaminophen-induced liver injury, an archetypal experimental model of sterile cell death and
102 conserved protein structure consists of the archetypal F-BAR domain linked to an SH3 domain by an in
106 lfonates (GSs) are a large and well-explored archetypal family of hydrogen-bonded organic host framew
111 a common active-site structure vis-a-vis the archetypal galactose 6-oxidase from Fusarium graminearum
112 utation is the first identified cause of the archetypal generalized photosensitive epilepsy syndrome,
114 We investigated topographic evolution in the archetypal glacial landscape of Fiordland, New Zealand,
116 ophage cell lines (HL-60; RAW 264.7) to kill archetypal Gram-positive (Staphylococcus aureus), Gram-n
118 (white-eyes, Zosteropidae) that contains an archetypal "great speciator." Our analyses show that the
123 in the case of Mus81-Eme1, is as good as the archetypal HJ resolvase RuvC in single turnover kinetic
128 monomeric polyglutamine is twofold: It is an archetypal IDP sequence and its aggregation is associate
129 nalyses, we interpret the phase behaviour of archetypal IDP sequences and demonstrate the rational de
130 ative studies of conformational ensembles of archetypal IDP sequences such as polyglutamine and glyci
133 Here we demonstrate that inhibition of the archetypal innate immune receptor CD11b/CD18 prevents pr
134 imer prompted us test the hypothesis that an archetypal integral membrane desaturase from Saccharomyc
135 lum Ca(2+) stores, fuelling speculation that archetypal intracellular Ca(2+) channels are the primary
136 y do some cells express small numbers of the archetypal intracellular Ca(2+) channels, IP(3)R and RyR
137 protein and RNA components stabilize various archetypal intracellular condensates-including the nucle
138 h calculation of phase diagrams for a set of archetypal intrinsically disordered low-complexity domai
141 rk has shown that the Tar-Tar(*) complex, an archetypal kissing loop, can form without Mg(2+), so lon
142 r carcinoma (HCC) genomes and elucidated two archetypal L1-mediated mechanisms enabling tumorigenesis
143 aviour of common boron starting materials as archetypal Lewis acids such that common routes to organo
146 ed polysaccharide utilization loci, with the archetypal locus sus (for starch utilisation system) enc
148 ate this through numerical simulations of an archetypal low-Reynolds-number swimmer, the "squirmer."
150 o reductase family 1 member A1 (AKR1A1), the archetypal mammalian SNO-CoA reductase, as a primary med
155 study, we identify a putative proto-MHC with archetypal markers in the most basal branch of Metazoans
156 rmula: see text] and [Formula: see text]O as archetypal materials for rock and ice, respectively, at
159 s requires the intramembrane UbiA enzyme, an archetypal member of a superfamily of prenyltransferases
162 nostatin, a clinical anticancer drug, is the archetypal member of the chromoprotein family of enediyn
163 el OMP assembly, the expression of cpxP, the archetypal member of the cpx regulon, was upregulated in
167 se permease (LacY) of Escherichia coli is an archetypal member of the major facilitator superfamily o
168 ell biology, that bluetongue virus (BTV), an archetypal member of the Reoviridae, utilizes the late e
169 membrane protein bacteriorhodopsin (bR), an archetypal member of the rhodopsin photoreceptor family,
172 occus aureus Sortase A protein (SrtA) is the archetypal member of the Sortase family and is activated
173 otein (Int) from bacteriophage lambda is the archetypal member of the tyrosine recombinase family, a
175 y for electrogenic NH(4)(+) transport in two archetypal members of the family, the transporters AmtB
177 data demonstrate a novel role for LTi cells, archetypal members of the innate lymphoid cell family, i
178 n the superconductivity of TaSe2, one of the archetypal members of the large family of layered dichal
179 a numerical analysis using dimensions for an archetypal merozoite to predict the respective contribut
182 ve reported previously that macrophages, the archetypal migratory cells, use the protease- and podoso
183 lass-A G-protein-coupled receptors and their archetypal model, rhodopsin, such as the apparent breaki
184 iagnose the source of these problems in four archetypal models and propose a density-dependent formul
185 echanisms and adsorption properties of three archetypal MOFs, namely MIL-100, ZIF-8 and HKUST-1.
189 operative than that found previously for the archetypal molten globule, alpha-lactalbumin (alpha-LA);
190 spectroscopic studies of compound 1 and the archetypal Molybdenum Blue (MB) wheel, {Mo(150)}, identi
193 terior brain regions, as compared to HC: (1) Archetypal MPDs (60% of MPDs) had increased frontal and
196 ith DEPDC5 mutations share features with the archetypal mTORopathy, tuberous sclerosis, raising the p
198 gories on the firm foundation of genes-as an archetypal natural kind-may be fundamentally flawed beca
199 Tourette's syndrome is widely regarded as an archetypal neurodevelopmental disorder of central, motor
200 and structures of such intermediates for the archetypal non-heme Fe(II) and alpha-ketoglutarate-depen
201 than expensive "designer" theophylline, the archetypal non-selective phosphodiesterase inhibitor.
202 beta(2)-adrenergic receptor (beta(2)AR), the archetypal nonvisual heptahelical receptor, as a model t
205 We highlight not only how it constitutes an archetypal object recognition system but also how it may
206 d-stress fluids and develop a nascent set of archetypal operations that can be performed with embedde
211 ny differences that might exist between this archetypal pair of atoms, and thereby to test the fundam
214 fullerenes is unprecedented, in part because archetypal PDIs are also electron deficient, making dyad
218 of unique CHD2 variants (3/36 cases) in the archetypal photosensitive epilepsy syndrome, eyelid myoc
220 synthase and establishing ESK1/TBL29 as the archetypal plant polysaccharide O-acetyltransferase, we
221 active metabolites of the widely distributed archetypal polycyclic aromatic hydrocarbon, benzo[a]pyre
223 ture and properties of excited states in the archetypal polythiophene are investigated via aggregates
224 we screened a peptide library, based on the archetypal pore-former melittin, for loss-of-function va
225 Nucleoside O-glycosylation represents an archetypal problem in chemical selectivity, inasmuch as
226 iquid droplet bound by surface tension is an archetypal problem in the study of the equilibrium shape
227 nd callosal projection neurons (CPN) are the archetypal projection neurons of the corticospinal tract
230 nic structure of excess electrons in liquids-archetypal quantum solutes-have been largely restricted
231 h structural bioinformatics, we generated an archetypal quaternary structural model of an ion channel
232 partly due to the conspicuous signatures of archetypal raised-leg postures in the accelerometer data
234 )ppGpp synthesis, and RNA binding unites two archetypal regulatory paradigms within a single protein.
236 bio-sciences, by developing tools to address archetypal representation and user interaction issues in
239 simplest, biologically relevant proteins and archetypal RNA molecules are sufficient for driving the
242 fluid flow and diffusion appropriate to the archetypal "rotational streaming" of algal species such
243 show that SsgB, a subfamily of SALPs, is the archetypal SALP that is functionally conserved in all sp
245 em realizes a laser-actuated analogue to the archetypal semiconductor spintronic device, the Datta-Da
247 the same as that of the previously reported archetypal sequence (type I) with only Y24EEL phosphoryl
248 ects of side chains using simulations of two archetypal sequences with amino acid compositions that a
250 Because platelets are anucleate and contain archetypal signal transduction machinery, they are ideal
251 evolutionary time frame coalesced to form an archetypal signaling pathway in bilateria that was expan
253 okalaemic periodic paralysis (hypoPP) is the archetypal skeletal muscle channelopathy caused by dysfu
254 f non-faceted, crystalline microspheroids of archetypal small molecular materials used in organic ele
255 llect high-quality binding responses for the archetypal small molecule inhibitors JM-2987 and TAK-779
257 oic acid, and 2,3-dihydroxybutanoic acid are archetypal specialty chemicals used in the synthesis of
258 n detected outside the galactic plane of the archetypal starburst galaxy M82 (refs 4 and 5), but so f
259 ar to be ideally modeled and analyzed by one archetypal statistical framework - the Graphical Probabi
260 ultrafast dynamics of quasi-particles in an archetypal strongly correlated charge-transfer insulator
261 these concepts with realistic studies of two archetypal strongly correlated materials, and corroborat
264 a solid-electrolyte inductive effect in the archetypal superionic lithium-ion conductor Li(10)Ge(1-x
267 onstrated by application of the method to an archetypal system involving a synthetic tripeptide known
268 honeycomb lattice provides a two-dimensional archetypal system to explore novel phenomena of geometri
271 related pathologies under the control of the archetypal T(H)2 cytokine interleukin-4 (IL-4) and was a
274 looping mediated by the Lac repressor is an archetypal test case for modeling protein and DNA flexib
277 not well understood and, paradoxically, the archetypal TNF-induced nuclear factor NFkappaB is anti-a
279 or cAMP-binding protein (CREB), which is the archetypal transcription factor binding to CRE, decrease
285 ly pathways, one of which is followed by the archetypal trimeric beta-barrel OMPs, OmpF and LamB, and
288 the restriction endonuclease activity of the archetypal Type I RM enzyme, EcoKI, in vitro indicating
289 RY, a process about 40 times faster than the archetypal tyrosine-Z oxidation in photosystem II, are d
290 igher (>tenfold) than those obtained with an archetypal ubiquitous promoter in a mouse model of hemop
292 from global indoor and outdoor averages, via archetypal urban and indoor settings, to 3646 real-world
293 d MMP-1(E200A) - an active-site mutant of an archetypal vertebrate collagenase - at increasing temper
295 ere proposed for the electronic detection of archetypal volatile anesthetic molecules such as diethyl
296 Despite sharing a common architecture with archetypal voltage-gated ion channels (VGICs), hyperpola