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1 ations in relevant host environments remains arduous.
2  protein complexes and interactions has been arduous.
3 educing chemical loads in the environment is arduous.
4 e for fuel cell reactions, but still remains arduous.
5 cting high quality research is also becoming arduous.
6  with a remarkable therapeutic potential and arduous administration.
7 oaches to investigating mycolylation rely on arduous analytical methods that occur outside the contex
8 on of explosives still poses a largely unmet arduous analytical problem, making their detection an is
9 ructure in a single casting process has been arduous and alternative approaches are desired.
10 gorithm designed for RetSynth streamlines an arduous and complex process in metabolic engineering.
11 d into ZIF-8 frameworks, typically requiring arduous and complicated post synthesis approaches.
12 o becoming a clinical academic researcher is arduous and convoluted, with many hurdles.
13        The current drug discovery process is arduous and costly, and a majority of the drug candidate
14 herapies for such respiratory diseases is an arduous and expensive process.
15                      However, the process is arduous and for high-throughput applications needs to be
16 , these antibody-discovery methods are often arduous and identify only a few candidates from numerous
17                                    Given how arduous and lengthy this process can be, we sought to de
18 h the circulatory system is one of the least arduous and less invasive interventions; however, this a
19                              This process is arduous and requires large amounts of RNA.
20 e-determining factor in new research, may be arduous and slow.
21 ny benchtop characterization methods require arduous and time-consuming procedures, and multiple assa
22 or improving surgical planning but can be an arduous and time-consuming task.
23                        This procedure may be arduous and time-intensive, potentially impacting the pa
24                     Current HCV treatment is arduous and uptake is low, but new highly effective and
25 ver, the process of isolating these cells is arduous, and the rarity of CSCs makes it difficult to te
26 cident pathology to disease outcomes without arduous annotation.
27  and assessment difficult and its management arduous as many drugs commonly used to treat complicatio
28     Important real-world decisions are often arduous as they frequently involve sequences of choices,
29 nt of various strategies that facilitate the arduous Au(I)/Au(III) redox cycle.
30                        Practically, the most arduous barrier to be overcome was the separation of the
31 egant, the path to clinical reality has been arduous because of the challenge on delivery technologie
32 er, the process of simulating such models is arduous because unconventional force fields and particle
33 estigators' lenses for decades, prompting an arduous but persistent race to uncover the mystery of th
34 e need for matrix-matched standards or other arduous calibration protocols and procedures to mitigate
35 ratory for the first time in 2004 through an arduous campaign involving novel strategies and tactics,
36 tional reactivation of p53 pathway, although arduous, can potentially provide a broad-based strategy
37 ntrolling target gene expression is still an arduous challenge.
38                               Therefore, the arduous charging procedure of the reaction autoclave in
39 ue to the need for complex chiral tethers or arduous chromatography.
40 onitoring at Deception Island because of the arduous climatic conditions and its remote location.
41 ata quality can fluctuate greatly during the arduous collection process, particularly via serial-sect
42 earch problem, is a demanding task requiring arduous efforts and tuning a large number of hyper-param
43 on process in drug discovery campaigns is an arduous endeavour where the input of many medicinal chem
44 rops, transformation and regeneration remain arduous even after more than 30 years of technological a
45 rowsing of chromatin contacts, thus reducing arduous Hi-C analysis into an easy yet flexible pipeline
46 ormance in individuals who are working long, arduous hours with limited access to food in environment
47 tions in real communities typically requires arduous identification of interactions in complex food w
48                                Many years of arduous investigation and the development of novel prote
49 y discovery methods, which can often rely on arduous literature searches.
50 tly speed up and automate what is usually an arduous manual process.
51 urrent 2D-LC technology requires a series of arduous method development activities poorly suited for
52 most vdWHs reported so far are created by an arduous micromechanical exfoliation and manual restackin
53  Frequently, such synthetic endeavors entail arduous, multiple-step de novo synthetic routes.
54 ve color mixing, which obviates the need for arduous nano-synthesis and expands on the color abundanc
55  the marginalized patient population and the arduous nature of current treatments.
56 lls, where alternative approaches are either arduous or frequently ineffective.
57 s with nonconvex data, while DBSCAN requires arduous parameter tuning.
58 methods or bond-order force fields requiring arduous parametrization.
59 icles have illustrated the long and at times arduous paths that led to the discovery of the first tra
60  a conventional banded karyotype followed by arduous positional cloning projects.
61  efficiencies make those techniques still an arduous process in hPSCs.
62 ave long passed and have been replaced by an arduous process in which a drug is designed to target a
63                                    Given the arduous process of mechanistically interrogating single
64 and physicochemical properties is a slow and arduous process.
65 ntifying bacteria in natural specimens is an arduous process.
66 ical staff should be prepared for a lengthy, arduous rehabilitation process.
67 ors have been made possible by extensive and arduous research.
68 ensitivity, specificity, or requirements for arduous sample preparation or signal amplification proce
69 evant discoveries have relied heavily on the arduous, somewhat subjective process of manual microscop
70 ry structure of such protein complexes is an arduous task and usually requires the combination of mul
71  elucidation of their structures has been an arduous task as the metabolites are obtained in vanishin
72             This will avoid the increasingly arduous task of extensive screening of bacteria and othe
73 e restoration sector faces the important but arduous task of implementing programmes to meet these ob
74 ng switching and memory while mitigating the arduous task of nanoscale patterning.
75 ecific histone PTMs to gene expression is an arduous task requiring large amounts of highly purified
76 biological data from these experiments is an arduous task that demands close attention to many detail
77 write this autobiography, although it was an arduous task to describe my journey through science: fir
78 olecular I-motifs has been a challenging and arduous task using conventional NMR spectral assignment
79                                   This is an arduous task with modest reproducibility and inconsisten
80  oxidized perovskite films is found to be an arduous task, filling some of oxygen vacancies into SrCo
81 al quality issues in GO is a challenging and arduous task, given its growing size.
82 ed by the need to generate training data, an arduous task, particularly in three dimensions.
83 ractability of the microbiome will remain an arduous task.
84 ization can be time-consuming and overall an arduous task.
85 ative sleep while cared for in the ICU is an arduous task.
86 istribution and aggregate architecture is an arduous task.
87 rning these electron transfers represents an arduous task.
88 oping selective Kv1.3 inhibitors is still an arduous task.
89  to experts to perform such an essential yet arduous task.
90 fe sciences research and biotechnology is an arduous task.
91 ing this hypothesis, however, constitutes an arduous task.
92 tools capable of aiding pathologists in this arduous task.
93 to the larger collection of mutations remain arduous tasks.
94 es, where collecting clinical samples can be arduous, the number of taxa considered in any one study
95 tion of silyl anion intermediates, which are arduous to achieve by other means, allows for the synthe
96                      However, they have been arduous to catalog and typically studied only in particu
97                               However, it is arduous to isolate and characterize the multitude of LSF
98 n of available states, makes it increasingly arduous to reach equilibrium in that regime.
99 ifficult to isolate from natural sources and arduous to synthesize.
100 which does not require specialist, and often arduous, training to use.
101 dt's initial discovery, there was a long and arduous transformation of ideas and paradigms that event
102 re needed to support them through a long and arduous treatment process.
103 of 0.954 and is therefore comparable to more arduous typing systems, such as pulsed-field gel electro
104 /MS and MS/MS data can be time-consuming and arduous when analyzed manually.
105 e three-dimensional (3-D) morphology remains arduous when the neuron has complex arborization and lon
106  into clinical candidates remains costly and arduous without detailed knowledge of the target.
107                                         This arduous work has yielded results with far-reaching conse

 
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