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6 r model suggests that the leading-head lever arm of a MVI dimer is uncoupled, in accord with the infe
7 secundigravidae who participated in the ISTp arm of a noninferiority trial in 4 West African countrie
8 of patients in the preemptive therapy (PET) arm of a randomized, controlled trial of PET versus valg
10 lar or complementary nucleobases on opposite arms of a chiral polyhydroxypyrrolidine while also ensur
11 igen-antibody structure in which the two Fab arms of a single antibody occupy the two arm regions of
12 in bacteria by unwinding the lagging-strand arm of abandoned DNA replication forks and reloading the
13 This finding was replicated in the placebo arm of ACE-IPF for those exposed to immunosuppression (h
15 en) who volunteered for the advanced imaging arm of ACRIN 6677, a substudy of the RTOG 0625 clinical
18 omal level, Tnt1 insertions occurred on both arms of all chromosomes, with insertion frequency negati
21 stributed decision making that exists in the arms of an octopus, we present a completely soft, stretc
22 ng penicillin allergy de-labeling into a new arm of antimicrobial stewardship programs (ASPs) has bec
23 her-infant pairs receiving all 3 recommended arms of antiretroviral prophylaxis or treatment (prenata
24 e present study, we amputate portions of the arms of Archaster typicus starfish, extract and separate
26 trioxide + prednisone), CALGB C9710 (single arm of ATRA + cytarabine + daunorubicin), Eastern Cooper
27 arubicin +/- prednisone), ALLG APML4 (single arm of ATRA + idarubicin + arsenic trioxide + prednisone
28 The studies included were ALLG APML3 (single arm of ATRA + idarubicin +/- prednisone), ALLG APML4 (si
32 The inclusion of metformin in the treatment arms of cancer clinical trials is based on improved surv
33 g of the intrinsically disordered C-terminal arm of CcdA to the toxin CcdB prevents CcdB from inhibit
35 s and autophagy are evolutionarily conserved arms of cell-autonomous immunity that restrict replicati
37 fection-based proteomics to identify pivotal arms of cellular signaling required for influenza virus
38 mutation; (b) the combined loss of the short arm of chromosome 1 and the long arm of chromosome 19, o
42 f the short arm of chromosome 1 and the long arm of chromosome 19, or 1p19q codeletion; and (c) methy
43 y-confirmed Parkinson's disease on the short arm of chromosome 20 (20pter-p12) and identify TMEM230 a
45 y and pathogenic variants affecting the long arm of chromosome 22 (22q) result in meningiomas in neur
46 haploid population mapped Rph1 to the short arm of chromosome 2H in a physical region of 1.3 megabas
48 domain containing genes, located on the long arm of chromosome 4, is expressed in a sharp peak during
49 se that is caused by a deletion in the short arm of chromosome 5 (5p) and has a variable clinical spe
50 ic disease caused by a deletion in the short arm of chromosome 5 (5p) with a variable clinical spectr
52 ation gave a rough map position on the upper arm of chromosome 5, and deep sequencing of DNA from the
53 the markers RM19291 and RM8072 on the short arm of chromosome 6, where a gene for resistance to BPH
54 eterozygosity for large portions of the long arm of chromosome 7, resulting in retention of only the
56 y of the CAN1 gene integrated onto the right arm of chromosome VIII did show expected increases or de
60 re in 8578 patients with T2DM in the placebo arm of DECLARE-TIMI 58 (Dapagliflozin Effect on Cardiova
61 6, or 12 months (group 2); or the reference arm of dose-adjusted VKA daily with a similar DAPT strat
63 lar cytotoxicity (ADCC) in vitro resulted in arming of effector cells in vivo, yet led to viral-decay
65 mab, an antibody binding to the dimerization arm of ErbB2, completely abolished the formation of cons
66 tfish (Ictalurus furcatus) from the northern arm of Eufaula Lake, a eutrophic multiuse impoundment in
68 of the genes encoding the predicted membrane arm of FHL-2 established surprisingly that the majority
71 ork-bound SSB loads PriA onto the duplex DNA arms of forks, suggesting a remodeling of PriA by SSB.
74 ur study reveals that NKT cells use distinct arms of glucose metabolism for their survival and functi
76 that the proposed strategy allowed the side arms of H(1)/H(2) to be sealed into the RNA sequence-pro
79 Mutant constructs for MuGENT require large arms of homology (>2000 bp) surrounding each genome edit
82 contribution of hyperactivation of the STAT3 arm of IL6 signaling on KRAS-driven lung tumorigenesis.
83 y circuit connecting the innate and adaptive arms of immunity are still ambiguous during experimental
84 The IL-17 receptor signaling and specific arms of immunity protect mice from long-term C. auris sk
86 TX3 is an essential component of the humoral arm of innate immunity, playing a nonredundant role in r
92 present much of the purpose of the catabolic arms of metabolism and then drive many anabolic pathways
96 ites on N(0) appear to be similar, and the C-arm of N provides a high flexibility and a propensity to
97 tachment of a GlcNAc on the alpha1,3 mannose arm of N-glycan is essential for FUT8-catalyzed core fuc
100 components of the planar cell polarity (PCP) arm of non-canonical Wnt signaling including VANGL1, VAN
101 Toward this end, the dangling phosphine arm of ((o-(Ph(2) P)C(6) H(4) )(3) )SbCl(2) AuCl (1) was
103 em represents one of the evolutionary oldest arms of our immune system and is commonly recognized as
105 pplying exclusions gave 39 publications in 3 arms of patient populations (adult, pediatric, and mixed
108 servational cohort studies and non-treatment arms of randomised controlled trials reporting proportio
109 e drug-coated balloon and drug-eluting stent arms of randomized clinical trials for both devices.
111 n type 1 receptor (AT1R) axis, a deleterious arm of RAS, unleashing its detrimental effects in diabet
113 RCA2 supports RAD51 loading on the regressed arms of reversed replication forks to protect them from
114 ing immunoprecipitation; ligation of the two arms of RNA duplexes via a linker; reverse transcription
115 HF in 8212 patients with T2DM in the placebo arm of SAVOR-TIMI 53 (Saxagliptin Assessment of Vascular
116 environment - both in terms of the afferent arm of sensation and the efferent arm of action - as a g
121 18991 study and 445 patients in the placebo arm of the 18071 study, were evaluated as reference coho
122 (EORTC), of 573 patients in the observation arm of the 18991 study and 445 patients in the placebo a
124 lphia (n = 77) and from the low tidal volume arm of the Acute Respiratory Distress Syndrome Network t
125 survive in an ocean of microbes without one arm of the adaptive immune defense suggests a high degre
127 tion of innate immune cells and the cellular arm of the adaptive immune system, via effects on antige
128 d a set of mutations that eliminated a major arm of the adaptive immune system-the MHC II pathway of
131 had received standard CPR in the amiodarone arm of the ALPS trial (Amiodarone, Lidocaine, or Placebo
132 2 diabetes mellitus from the Lipid Lowering Arm of the Anglo Scandinavian Cardiac Outcomes Trial (AS
134 tin, proteins, and antibodies, such as a Fab arm of the antibody Herceptin and a designed antibody De
135 electively interferes with an usher-specific arm of the BAM complex, revealing new details of the ush
136 To establish the physiological roles of this arm of the checkpoint, we analyzed separation of functio
138 lexus, midthigh, proximal calf, and midupper arm of the clinically more affected side using high-reso
139 Cry1 and Cry2, which abolishes the negative arm of the clock transcription-translation feedback loop
140 for re-engaging the positive transcriptional arm of the clock, as well as a potential route to manipu
141 hat, in wild-type parasites, the Manalpha1-6 arm of the conserved trimannosyl core may carry predomin
142 a marker for activation of the inflammatory arm of the contact system, is increased in a mouse model
143 ges histones and nucleosomal DNA through one arm of the core structure, composed of the Rsc8 SWIRM do
145 omimetic mutation in the flexible N-terminal arm of the CP increased BMV RNA replication and virion p
147 tein cofilin to stimulate the depolymerizing arm of the cycle, how PAK1 might trigger the polymerizin
150 s negatively regulated by the PERK-eIF2alpha arm of the endoplasmic reticulum UPR pathway, independen
151 oteostatic machinery and the IRE1-alpha-MKK4 arm of the endoplasmic-reticulum-stress-response pathway
152 major bleeding at 30 days in the bivalirudin arm of the EUROMAX trial did not translate into reduced
153 ocular glands contribute to resistance as an arm of the eye-associated lymphoid tissue and may also b
155 ti-human CD20 antibody (2H7), with the other arm of the FP an anti-chelated radiometal trap for a rad
159 ell response while increasing the regulatory arm of the immune response in animals models of autoimmu
161 ity because of the established role for this arm of the immune system in other gastrointestinal infla
162 ely focused on T lymphocytes, but the innate arm of the immune system might be similarly important.
164 Natural killer (NK) cells form an important arm of the innate immune system and function to combat a
165 complement alternative pathway is a powerful arm of the innate immune system that enhances diverse in
168 PKR-like endoplasmic reticulum kinase (PERK) arm of the Integrated Stress Response (ISR) is implicate
169 e-cell anatomical analysis reveals that each arm of the LPLC2 cross-shaped primary dendrites ramifies
174 istinct rule choices for the innate immunity arm of the model between younger and aging mice in respo
175 plained by reduced flux through the amidated arm of the NAD+ salvage pathway due to reduced sirtuin a
176 el domains is stabilized by the dimerization arm of the neighboring protomer, providing a structural
177 correlated with activation of the canonical arm of the NF-kappaB pathway, a major pathway linked to
179 demonstrate that inhibition of the oxidative arm of the pentose phosphate pathway (oxPPP) is required
181 ng in the activation of the antiinflammatory arm of the PI3K pathway that serves to educate CD4(+) Tr
182 MACE events were infrequent, with 2 in each arm of the planned invasive group and 1 in the planned n
184 -risk SMM patients included in the treatment arm of the QUIREDEX trial, and with longitudinal periphe
187 diagnosis rate observed in the intervention arm of the RHIVA2 randomised controlled trial done in Ha
188 1 dose of the study drug in the on-treatment arm of the ROCKET AF (Rivaroxaban Once-daily Oral Direct
189 cells indicates that IL-1 controls the late arm of the senescence secretome, which consists of proin
192 om an unexpected seroconverter in the 300-mg arm of the SSAT040 TMC278LA pharmacokinetic study for ri
195 of 303 patients were randomly assigned to an arm of the study at the time of interim analysis (Januar
197 the 12 participants in the active treatment arm of the SYCAMORE study, 11 (92%) were restarted on ad
198 circadian rhythm by stabilizing the negative arm of the transcription/translation feedback loop witho
199 orted procedural success rate in the CTO PCI arm of the trial was 77%, and the adjudicated success ra
201 tion did not allow the staff to be masked to arm of the trial; however, randomisation was done in bat
202 ed predicted tRNA-binding domain binds the T-arm of the tRNA for alanine with conserved lysine residu
204 lective pharmacologic activation of the ATF6 arm of the unfolded protein response (UPR) during reperf
206 the activating transcription factor 6 (ATF6) arm of the UPR in mitigating adverse outcomes associated
208 e R-like endoplasmic reticulum kinase (PERK) arm of the UPR in the regulation of skeletal muscle mass
210 lectively, our results suggest that the PERK arm of the UPR plays a pivotal role in the regulation of
212 RNA-like endoplasmic reticulum kinase (PERK) arm of the UPR was activated, as the expression of both
213 BP1), a major downstream target of IRE1alpha arm of the UPR, ameliorates muscle wasting in LLC tumor-
214 nal expression of genes directed by the PERK arm of the UPR, including genes involved in amino acid m
220 ent in the low- and high-intensity treatment arms of the Acute Renal Failure Trial Network and RENAL
221 respectively, according to the intervention arms of the acute respiratory distress syndrome network
224 ined neuronal tracer injections into various arms of the circuit through specific DA subpopulations t
225 Two waves propagating in the orthogonal arms of the cross may accumulate significantly different
226 s is known about the importance of these two arms of the defence for the ecology and evolution of pro
227 mab plus prompt and deferred laser treatment arms of the Diabetic Retinopathy Clinical Research Netwo
228 as hyperactivity, increased time in the open arms of the elevated plus maze and increased immobility
229 e preference, and decreased time in the open arms of the elevated plus maze relative to control mice.
230 sive stimuli and spent less time in the open arms of the elevated plus maze, indicating high levels o
231 n exaggerated activation of the proapoptotic arms of the endoplasmic reticulum stress response that i
232 osture impacts the muscle lengths and moment arms of the extrinsic finger muscles that cross the wris
237 The appropriate orchestration of different arms of the immune response is critical during viral inf
238 r hand, studies of the workings of different arms of the immune response, and their relative importan
239 insight into the interplay between different arms of the immune system and the role of ectoparasites
240 e susceptibility shed light on how different arms of the immune system are involved in three viral in
241 ) infection confirms the innate and adaptive arms of the immune system as drivers of viral evolution.
242 iding a better understanding of how multiple arms of the immune system cooperate to achieve an optima
243 tem, harnessing both the innate and adaptive arms of the immune system might produce superior tumour
244 (LNs), activate both the innate and adaptive arms of the immune system, and persist for a sufficient
245 training have been shown to benefit multiple arms of the immune system, we hypothesized that higher l
246 lhe40 in the circulating and tissue-resident arms of the immune system, with emphasis on recent work
251 okine that activates the innate and adaptive arms of the immune system; however, the administration o
253 Monocytes and macrophages represent critical arms of the innate immune system and are considered regu
255 ant growth forced a decision between the two arms of the maze, fans alone were able to influence grow
256 ge HER2-positive breast cancer in 2 of the 3 arms of the N9831 trial were assessed for STILs at an ac
258 erones by tau aggregates interferes with two arms of the proteostasis network, likely having profound
260 and 3-year mortality rates in both treatment arms of the RCT to identify patient groups that should b
262 ith atrial fibrillation from the 3 treatment arms of the RE-LY trial (Randomized Evaluation of Long-T
264 er, the use of an adaptor that links the two arms of the RNA duplex permits hiCLIP to unambiguously i
268 ycles of chemotherapy were completed on both arms of the study by approximately 50% of the patients.
270 ulated by both the MyD88- and TRIF-dependent arms of the TLR signaling pathway, 3) MyD88 splicing is
273 igned to either of the 2 active intervention arms of the trial showed similar CVD risk to those with
274 ge on PROMs was similar for patients in both arms of the trial, with no statistically significant dif
277 naling mechanisms and the role of individual arms of the UPR in the regulation of skeletal muscle mas
278 vel interplay between PERK and the XBP1-ATF6 arms of the UPR, whereby PERK attenuates the expression
281 e activating transcription factor 6-mediated arm of this response through Xbp1 and downstream activat
285 reased significantly more in the ranibizumab arm of this subgroup compared with the bevacizumab arm.
287 head domain and in flexing of the anticodon arm of tRNA suggests that they represent general strateg
288 ation of Bmal1, which abolishes the positive arm of TTFL, causes up-regulation of the c-MYC protein l
290 kidney function in the intensive BP lowering arm of two trials in CKD associated with higher risk of
291 who were screened regularly from the placebo arms of two large prostate cancer prevention trials (Pro
292 l-requiring enzyme 1/X-box binding protein 1 arm of UPR abolished the cell migration effect of CTB-KD
293 plex response and to function as an effector arm of vaccine-induced humoral adaptive antibacterial im
294 nterpentamer contacts mediated by N-terminal arms of VP2 capsid proteins, which result in the expansi
295 NB_ARC contigs showed identity with the long arm of wheat chromosome 6B confirming the introgression
298 were recruited, with 447 to the intervention arm, of which 346 (77.4%) were engagers and 130 (29.1%)
299 (5,790 in intervention arm; 7,104 in control arm), of whom 9,927 (77.0%) were contacted at least once
300 test, and entries and duration in the novel arm of Y maze test, with acute onset and various timecou