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1 rs was determined by measurement of original Aroclors.
2 Three represent relatively unweathered Aroclors.
3 easured in the sediment were not detected in Aroclors.
4 East Chicago, IN and five original Monsanto Aroclors.
5 sent in above-trace quantities in commercial Aroclors.
6 ater than trace concentrations in commercial Aroclors.
7 levels in sediments and less than 0.0025% in Aroclors.
10 duced deletions in vivo in the mouse embryo; Aroclor 1221 and Aroclor 1260 induced deletions in yeast
12 es strongly resembled the OH-PCB profiles of Aroclors 1221, 1242, 1248, and 1254, yet 25% of OH-PCBs
13 PLA2 that are linked to different functions: Aroclor 1242 activates a calcium-independent PLA2 that r
16 AA release and O2- production in response to Aroclor 1242 were inhibited by bromoenol lactone (BEL),
17 hat are activated by the neutrophil stimuli, Aroclor 1242, a mixture of polychlorinated biphenyls, an
23 d placental anti-angiogenesis in response to Aroclor 1254 (A-1254), a mixture of polychlorinated biph
24 or 6 mg/kg/day of a commercial PCB mixture, Aroclor 1254 (A1254) by gavage from gestational day (GD)
26 stribution patterns indicate historic use of Aroclor 1254 as well as modern sources of non-Aroclor co
30 e effects of ecologically relevant levels of Aroclor 1254, a polychlorinated biphenyl (PCB) mixture,
31 nvestigated how exposure to Aroclor 1016 and Aroclor 1254, as well as a newly characterized non-Arocl
32 tive stress were influenced mainly by PB and Aroclor 1254, indicative of an oxidative damage response
33 rs (beta-naphthoflavone, phenobarbital (PB), Aroclor 1254, isoniazid, pregnenolone 16alpha-carbonitri
34 ent of PCB congeners in factors, relative to Aroclor 1254, suggested biotransformation (via cytochrom
38 ow), 0.70 (intermediate), or 1.05 (high) mug Aroclor 1254/g-body weight by gavage from 1 through 18 d
39 nated most hexa- and heptachlorobiphenyls in Aroclor 1260 (50 mug/mL) leading to losses of 51% and 20
40 high molecular weight formulations, such as Aroclor 1260 and PCBs 206, 208, and 209 produced during
44 responsible for extensive dechlorination of Aroclor 1260, and finally to the identification of a Deh
45 D14 dechlorinated the commercial PCB mixture-Aroclor 1260-mainly by removing flanked para- and doubly
48 B-209, which was manufactured at the site in Aroclor 1270 and 1271, was the most abundant congener in
52 ic chemicals with both legacy sources (e.g., Aroclors) and new sources (e.g., unintentional contamina
54 to report levels of OH-PCBs in sediment and Aroclors, and our discovery is significant because it is
55 highly weathered as to be unrecognizable as Aroclors, and thus have probably resided in the river fo
56 factors were probably originally related to Aroclors, but they are so highly weathered as to be unre
59 roclor 1254 as well as modern sources of non-Aroclor congeners associated with paint pigments and sur
60 L laboratory mesocosms containing weathered Aroclor-contaminated sediment from Baltimore Harbor, MD,
61 ilized Aroclors (gaseous PCBs) and unaltered Aroclors (dissolved PCBs) dominate in some samples, ongo
63 between schools and indicated the sources as Aroclors from building materials and individual PCBs ass
64 rization indicated that although volatilized Aroclors (gaseous PCBs) and unaltered Aroclors (dissolve
65 ociations of PCB congener distributions with Aroclors in most foods and found manufacturing byproduct
66 se commercial mixtures of PCBs, analogous to Aroclors in the United States) is reduced from 20- or 50
67 f non-Aroclor PCB congeners (</=0.20 wt % in Aroclor) in human serum collected from urban and rural a
69 r 1254, as well as a newly characterized non-Aroclor mixture that resembles the PCB profile found in
70 ons of polychlorinated biphenyls (PCBs) from Aroclor mixtures present in building materials explain t
72 olescents have significantly lower total non-Aroclor PCB concentrations than mothers in East Chicago
75 There are significant differences in non-Aroclor PCBs between East Chicago community and Columbus
78 PCBs) dominate in some samples, ongoing non-Aroclor sources such as paints/pigments (PCB 11) and coa
79 thesized that there are both Aroclor and non-Aroclor sources within a single school and that PCB conc
80 exhibited congener patterns consistent with Aroclor weathering, suggesting potential PCB metabolism
82 with high potency (EC50=1.4 microM), whereas Aroclors with either high or low chlorine composition sh