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1 ot cause B. burgdorferi 25015 to become more arthritogenic.
2 lting mutant rCB10T614P,A617E product became arthritogenic.
3 esulting mutant CB8P449T,E452A was no longer arthritogenic.
4 ing a role for DEL-1 in the induction of the arthritogenic Ab response.
5 a faecal bacterial strain that has exhibited arthritogenic activity in animal models and that favours
6 esponses to stimulation with a citrullinated arthritogenic aggrecan peptide were detected in RA patie
7 long-term modulation of T cells specific for arthritogenic Ags.
8                 These findings indicate that arthritogenic alphavirus infection drives a unique myelo
9 rthritis and polyarthralgia is a hallmark of arthritogenic alphavirus infections, with an exceptional
10  of vaccine design against multiple emerging arthritogenic alphavirus infections.
11  Furthermore, due to the explosive nature of arthritogenic alphavirus outbreaks and their recent expa
12              Chikungunya virus (CHIKV) is an arthritogenic alphavirus that causes both debilitating a
13              Chikungunya virus (CHIKV) is an arthritogenic alphavirus that causes debilitating muscul
14         Recent epidemics caused by CHIKV, an arthritogenic alphavirus, resulted in more than 8.5 mill
15 isease signs in mice infected with a related arthritogenic alphavirus, Ross River virus, but not in m
16 culture-adapted strains of Sindbis virus, an arthritogenic alphavirus.
17 f mice infected with Mayaro virus, a related arthritogenic alphavirus.
18  of new expression vectors for two Old World arthritogenic alphaviruses (Sindbis and Chikungunya viru
19                                              Arthritogenic alphaviruses are arboviruses (arthropod-bo
20                                         Most arthritogenic alphaviruses are currently limited to spec
21 ing antibodies that protect against multiple arthritogenic alphaviruses are elicited during natural i
22                                              Arthritogenic alphaviruses are globally distributed, mos
23                                              Arthritogenic alphaviruses are human pathogens maintaine
24  in a manner that is similar to the way that arthritogenic alphaviruses bind to the structurally unre
25          IMPORTANCE The globally distributed arthritogenic alphaviruses have infected millions of hum
26 or functions that affect the pathogenesis of arthritogenic alphaviruses have not been defined.
27                                              Arthritogenic alphaviruses including Ross River virus (R
28 gs shed light on how preexisting immunity to arthritogenic alphaviruses may affect secondary infectio
29 res to anticipate and mitigate the impact of arthritogenic alphaviruses on human health.
30          Mosquito inoculation of humans with arthritogenic alphaviruses results in a febrile syndrome
31 hritic infiltrates seen after infection with arthritogenic alphaviruses such as chikungunya virus.
32                                              Arthritogenic alphaviruses such as Ross River virus (RRV
33             Mxra8 is a receptor for multiple arthritogenic alphaviruses that cause debilitating acute
34  a member of a globally distributed group of arthritogenic alphaviruses that cause weeks to months of
35 a receptor for chikungunya (CHIKV) and other arthritogenic alphaviruses with mammalian hosts.
36 ments or vaccines are not available for most arthritogenic alphaviruses, and recently licensed vaccin
37 d Irf1 (-/-) mice with two distantly related arthritogenic alphaviruses, chikungunya virus (CHIKV) an
38 -1 in modulating pathogenesis of two related arthritogenic alphaviruses, chikungunya virus and Ross R
39                                              Arthritogenic alphaviruses, including chikungunya virus
40 es the tropism and pathogenesis for multiple arthritogenic alphaviruses, including chikungunya virus
41 butes to control of RRV infection.IMPORTANCE Arthritogenic alphaviruses, including Ross River virus (
42                                              Arthritogenic alphaviruses, including Ross River virus (
43                                              Arthritogenic alphaviruses, including Ross River virus (
44 ied receptor for several clinically relevant arthritogenic alphaviruses, its detailed role in the cel
45                                   Like other arthritogenic alphaviruses, mechanisms of CHIKV pathogen
46  understanding of the transmission cycles of arthritogenic alphaviruses, their vectors, epidemiology,
47 a subset of these inhibited multiple related arthritogenic alphaviruses.
48                 Mice were inoculated with an arthritogenic amount of S. aureus intravenously or by lo
49 eactive antibodies that protect against both arthritogenic and encephalitic alphaviruses have not bee
50                           While infection by arthritogenic and encephalitic alphaviruses results in d
51 e antiviral activity of mouse Ifitm3 against arthritogenic and encephalitic alphaviruses using cells
52 ntigen on the surface of cells infected with arthritogenic and encephalitic alphaviruses.
53 s, we define CHIKV epitopes conserved across arthritogenic and encephalitic viruses.
54 1A(low) T cells were tissue-invasive and pro-arthritogenic, and MRE11A reconstitution mitigated synov
55 itiate disease by helping B cells to produce arthritogenic anti-glucose-6-phosphate isomerase (anti-G
56 is and is induced by well-defined monoclonal arthritogenic antibodies and enhanced by injection of li
57 ital imaging to demonstrate that transfer of arthritogenic antibodies caused macromolecular vasoperme
58 not rely on identification of the initiating arthritogenic antigen.
59 /c mice expressing a TCR that recognizes the arthritogenic ATEGRVRVNSAYQDK peptide of human cartilage
60 not autoimmune disease models independent of arthritogenic autoantibodies.
61 ease by providing help to B cells to produce arthritogenic autoantibodies.
62 d found to be supported by the cotransfer of arthritogenic autoantibodies.
63 ction as antigen-presenting cells (APCs) for arthritogenic autoantigens found within inflamed joint t
64 both the inhibition and amplification of the arthritogenic B cell response.
65                    The mechanisms applied to arthritogenic B cells expressing antigen-specific B cell
66       In patients with rheumatoid arthritis, arthritogenic B cells often up-regulate Bcl(XL) expressi
67                                          The arthritogenic cells showed an enrichment for TCR variabl
68 is (RA); however, their specific role in key arthritogenic cells such as the synovial fibroblast (SF)
69 .315 protects mice against infection by both arthritogenic (chikungunya and Mayaro) and encephalitic
70 of the hybrids cross-reacted with either the arthritogenic CII 445-453 or murine CII.
71                               In these mice, arthritogenic cytokine may be produced by neutrophils th
72 une signals, including TLR4 agonists and the arthritogenic cytokine, IL-1beta, via an NFkappaB pathwa
73 can alter the spectrum of cells that produce arthritogenic cytokines.
74 verity of AA, despite responding well to the arthritogenic determinant within Bhsp65.
75  health and can cause lethal encephalitic or arthritogenic disease in humans and animals.
76 presentative alphavirus causing debilitating arthritogenic disease in humans.
77 nal antibody therapy that aborted lethal and arthritogenic disease in wild-type and immunocompromised
78 vectored viruses that primarily cause either arthritogenic disease or acute encephalitis.
79 Alphaviruses are a reemerging viral cause of arthritogenic disease.
80 at causes acute, subacute, and chronic human arthritogenic diseases and, in rare instances, can lead
81 tion of HCG was initiated 2 days prior to an arthritogenic dose of streptococcal cell wall (SCW) in n
82 W (3 microg/day), initiated 7 days before an arthritogenic dose of systemic SCW, virtually eliminated
83 in normal adult articular cartilage, and the arthritogenic epitope(s) remains intact in G1-containing
84 ntained within aa 84 to 113 is a potentially arthritogenic epitope.
85                             Tenascin-C is an arthritogenic extracellular matrix glycoprotein that is
86                            Processing of the arthritogenic glycosylated CII(259-273) epitope, which i
87 ar processing of CII for presentation of the arthritogenic glycosylated epitope CII(259-273) to CD4 T
88 enerated antigenic CII fragments bearing the arthritogenic glycosylated epitope, 2) the antigenic CII
89  and keratan sulfate (KS) side chains of the arthritogenic human proteoglycans are removed.
90                       Here, we show that the arthritogenic Igs act through both Fc receptors (in part
91 tilage proteoglycan aggrecan, is immunogenic/arthritogenic in BALB/c mice.
92  observations demonstrate that fibrinogen is arthritogenic in mice and that the pathogenesis of FIA i
93 e acute Lyme arthritis by enhancing an acute arthritogenic inflammatory response initiated by spiroch
94 n is induced in C57BL/6J mice by transfer of arthritogenic K/BxN serum and allowed to resolve.
95                                 Injection of arthritogenic K/BxN serum triggered robust arthritis in
96 d with distinct protocols and volumes of the arthritogenic K/BxN serum, and periodontal bone damage.
97 und hyperproliferation of synovial cells and arthritogenic lymphocytes and heightened the production
98 deglycosylated appropriately, can be used as arthritogenic material in BALB/c mice.
99 in FcgammaRIII-driven production of critical arthritogenic mediators including IL-1beta and CXCL2.
100 ificantly reduced serum levels of a panel of arthritogenic mediators, including chemokines such as MI
101 cell, together with enhanced availability of arthritogenic microbial antigens caused by microbial per
102              Chikungunya virus (CHIKV) is an arthritogenic mosquito-transmitted alphavirus that is un
103 y Th2 (IL-4 and IL-10) cytokines whereas the arthritogenic mutant rCB10 induced predominantly Th1 (IF
104       These viruses are classified as either arthritogenic or encephalitic based on their genetic rel
105                    Alphaviruses cause severe arthritogenic or encephalitic disease.
106            Dominant T-cell recognition of an arthritogenic OspA epitope is one way in which the immun
107 mplex (MHC) binding sites of the immunogenic/arthritogenic p135H sequence.
108 t that an alternative complement-independent arthritogenic pathway could be operative in the absence
109    Our results suggest an alternative to the arthritogenic peptide hypothesis.
110 DR10 shows that there could even be a single arthritogenic peptide; we now suggest a possible consens
111 ricted immune responses to self-antigens, or arthritogenic peptides, might drive immunopathology.
112 d from future researches involving potential arthritogenic peptides.
113 th, rather than a predilection for selecting arthritogenic peptides.
114 eful in determining whether HLA-B27 presents arthritogenic peptides.
115 ity of HLA-B27 confers an ability to present arthritogenic peptides.
116 leles displaying a binding site for similar "arthritogenic" peptides.
117 D4+ T cells expressing a TCR specific for an arthritogenic PG epitope is sufficient to trigger sponta
118 - mice are a promising model to evaluate the arthritogenic potential of human autoAbs.
119 SKG CD4 T cells marked their autoreactivity, arthritogenic potential, and ability to more readily dif
120 led to serve as an adjuvant in the immune or arthritogenic response to type II collagen in mice.
121                               However, their arthritogenic role remains undefined.
122 ually detectable synovitis after transfer of arthritogenic sera.
123 pleting mAb before and following transfer of arthritogenic serum and scored for clinical indications
124 e early inflammatory response to transferred arthritogenic serum from the K/BxN transgenic mouse.
125 ligand, lipopolysaccharide, concomitant with arthritogenic serum in IL-1 receptor-deficient mice resu
126  in K/BxN joint inflammation by transferring arthritogenic serum into a panel of genetically deficien
127 either partial or complete protection in the arthritogenic serum transfer and the more aggressive gen
128 diated arthritis, induced by the transfer of arthritogenic serum.
129           Furthermore, B cells isolated from arthritogenic splenocytes treated in vitro with anti-IL-
130  this study we have shown that activation of arthritogenic splenocytes with antigen and agonistic ant
131                     Syngeneic fibroblasts or arthritogenic splenocytes, engineered to express tsCR1 u
132                                           An arthritogenic strain of Subdoligranulum in the gut elici
133 hiMFV1 and the recently described phiMAV1 of arthritogenic strains of Mycoplasma arthritidis, along w
134 r sequencing (scTCR-Seq) to profile a highly arthritogenic subset of naive CD4+ T cells from BALB/c-Z
135 mosquitoes and known to cause a debilitating arthritogenic syndrome.
136                One of the cross-reactive and arthritogenic T cell epitopes (92GR/QVRVNSA/IY) is local
137                      The critical autoimmune/arthritogenic T cell epitopes of aggrecan are located in
138 ult proteoglycan inhibits the recognition of arthritogenic T cell epitopes, prevents the development
139      Fine epitope sequence recognition of an arthritogenic T cell hybridoma derived from p135H-primed
140 nique effects on priming of autoreactive and arthritogenic T cells, provides new insight for understa
141  mediating autoimmune arthritis, we isolated arthritogenic TCRs and characterized the self antigens t
142 ion and function resulting in suppression of arthritogenic Th17 cells and CIA.
143 s and differ from infections caused by other arthritogenic viruses, such as Ross River virus.

 
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